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The map label for this gene is thrB

Identifier: 114330788

GI number: 114330788

Start: 792598

End: 793548

Strand: Reverse

Name: thrB

Synonym: Neut_0775

Alternate gene names: 114330788

Gene position: 793548-792598 (Counterclockwise)

Preceding gene: 114330789

Following gene: 114330787

Centisome position: 29.82

GC content: 47.63

Gene sequence:

>951_bases
ATGTCTGTTTTCACCCCGGTTACCAAAAAGCAACTTGCCGTCTGGCTGCAGAATTACTCACTTGGATCACTGACTGATTT
GCAGGGTATTTCATCCGGAATCGAAAATACCAATTATTTTGTTACCACGACACAAGGCAAATTTATTCTCACTCTGTTCG
AGAAGCTAACCAGCACTGAATTGCCCTTTTATCTCAATCTGATGGCGTATCTCTCCGAGCAGGGTATTCCCTGCCCCAAA
CCTATTGAATCACAAGATCACGCTTTGCTAGGTACTCTCAATGGCAAACCGGCCTCTATTGTGAGCTTTCTACCCGGGCA
ATCCATGACACAAATCAGAGAAGAACAATGTGCACAGGTCGGAGAAATACTCGCCAAAATGCACCTGGCAGGACTAAACT
ACAATGGTAAAAACAGAAACCCGCGCGGACTGGATTGGTGGCAAACTGCTGCTGGAACAGTCATGCCCTTCCTTTCCCGC
TCGGAGCAAAGCCTGCTCGATGAGGAGTTGCAATTCCAGATAAAGCAGCGCACAACCAACCTTCCTCAAGGCATTATCCA
TGCCGATCTTTTCCGTGATAACGTTTTATTTACATCCACCGGCATTGGCGGAATTATCGACTTCTACTTTGCCTGTAATG
ATGCTTTACTATACGATCTGGCTATTACTGCAAACGACTGGTGTACGCTTGGGGACGGCGTAATGGACAAAGCGCGCATG
CATGCCCTCGTGAAGGCCTACCAGGCCGCCCGACCATTAACAGCGGAAGAATACCCTGCCTGGCCTGCTATGCTACGGGC
AGGTGCACTGCGTTTTTGGTTATCACGTCTATATGACTATTATCTGCCTCGCCCGGGTGAGTTGACACATAAAAAGGATC
CAGAATACTTCAGAAAAATTCTGGAATATCATCTGACCAATCCGAGTGTACTACCCTCTCTTCAGGCTTGA

Upstream 100 bases:

>100_bases
CTTTTGAGCAAGATTCACCGGAACCTGAGCGATCTCCAGTAAACTTGCTGGTTTATTTGCCATCCCATCCTTTACAAACT
GCCTTTTCAGTACTTCATTC

Downstream 100 bases:

>100_bases
AGCCAAACAGATTATCGTTATCCTTTTCACATACGCTCTATAAACAATTAAAATTCTGGCCGGGCGTACTTTAATTACTG
GAGAAATACGATGGAAGCAC

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSVFTPVTKKQLAVWLQNYSLGSLTDLQGISSGIENTNYFVTTTQGKFILTLFEKLTSTELPFYLNLMAYLSEQGIPCPK
PIESQDHALLGTLNGKPASIVSFLPGQSMTQIREEQCAQVGEILAKMHLAGLNYNGKNRNPRGLDWWQTAAGTVMPFLSR
SEQSLLDEELQFQIKQRTTNLPQGIIHADLFRDNVLFTSTGIGGIIDFYFACNDALLYDLAITANDWCTLGDGVMDKARM
HALVKAYQAARPLTAEEYPAWPAMLRAGALRFWLSRLYDYYLPRPGELTHKKDPEYFRKILEYHLTNPSVLPSLQA

Sequences:

>Translated_316_residues
MSVFTPVTKKQLAVWLQNYSLGSLTDLQGISSGIENTNYFVTTTQGKFILTLFEKLTSTELPFYLNLMAYLSEQGIPCPK
PIESQDHALLGTLNGKPASIVSFLPGQSMTQIREEQCAQVGEILAKMHLAGLNYNGKNRNPRGLDWWQTAAGTVMPFLSR
SEQSLLDEELQFQIKQRTTNLPQGIIHADLFRDNVLFTSTGIGGIIDFYFACNDALLYDLAITANDWCTLGDGVMDKARM
HALVKAYQAARPLTAEEYPAWPAMLRAGALRFWLSRLYDYYLPRPGELTHKKDPEYFRKILEYHLTNPSVLPSLQA
>Mature_315_residues
SVFTPVTKKQLAVWLQNYSLGSLTDLQGISSGIENTNYFVTTTQGKFILTLFEKLTSTELPFYLNLMAYLSEQGIPCPKP
IESQDHALLGTLNGKPASIVSFLPGQSMTQIREEQCAQVGEILAKMHLAGLNYNGKNRNPRGLDWWQTAAGTVMPFLSRS
EQSLLDEELQFQIKQRTTNLPQGIIHADLFRDNVLFTSTGIGGIIDFYFACNDALLYDLAITANDWCTLGDGVMDKARMH
ALVKAYQAARPLTAEEYPAWPAMLRAGALRFWLSRLYDYYLPRPGELTHKKDPEYFRKILEYHLTNPSVLPSLQA

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KHSE_NITEC (Q0AHY7)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747010.1
- ProteinModelPortal:   Q0AHY7
- SMR:   Q0AHY7
- STRING:   Q0AHY7
- GeneID:   4272964
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0775
- NMPDR:   fig|335283.3.peg.2378
- eggNOG:   COG2334
- HOGENOM:   HBG309377
- OMA:   ADLFRDN
- ProtClustDB:   PRK05231
- BioCyc:   NEUT335283:NEUT_0775-MONOMER
- HAMAP:   MF_00301
- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009
- TIGRFAMs:   TIGR00938

Pfam domain/function: PF01636 APH; SSF56112 Kinase_like

EC number: =2.7.1.39

Molecular weight: Translated: 35554; Mature: 35423

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFTPVTKKQLAVWLQNYSLGSLTDLQGISSGIENTNYFVTTTQGKFILTLFEKLTSTE
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCC
LPFYLNLMAYLSEQGIPCPKPIESQDHALLGTLNGKPASIVSFLPGQSMTQIREEQCAQV
CCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHH
GEILAKMHLAGLNYNGKNRNPRGLDWWQTAAGTVMPFLSRSEQSLLDEELQFQIKQRTTN
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
LPQGIIHADLFRDNVLFTSTGIGGIIDFYFACNDALLYDLAITANDWCTLGDGVMDKARM
CCCHHHHHHHHHCCEEEEECCCHHHHHHHHHCCCEEEEEEEEECCCCEECCCHHHHHHHH
HALVKAYQAARPLTAEEYPAWPAMLRAGALRFWLSRLYDYYLPRPGELTHKKDPEYFRKI
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LEYHLTNPSVLPSLQA
HHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SVFTPVTKKQLAVWLQNYSLGSLTDLQGISSGIENTNYFVTTTQGKFILTLFEKLTSTE
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCC
LPFYLNLMAYLSEQGIPCPKPIESQDHALLGTLNGKPASIVSFLPGQSMTQIREEQCAQV
CCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHH
GEILAKMHLAGLNYNGKNRNPRGLDWWQTAAGTVMPFLSRSEQSLLDEELQFQIKQRTTN
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
LPQGIIHADLFRDNVLFTSTGIGGIIDFYFACNDALLYDLAITANDWCTLGDGVMDKARM
CCCHHHHHHHHHCCEEEEECCCHHHHHHHHHCCCEEEEEEEEECCCCEECCCHHHHHHHH
HALVKAYQAARPLTAEEYPAWPAMLRAGALRFWLSRLYDYYLPRPGELTHKKDPEYFRKI
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LEYHLTNPSVLPSLQA
HHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA