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The map label for this gene is ppnK

Identifier: 114330781

GI number: 114330781

Start: 784264

End: 785154

Strand: Reverse

Name: ppnK

Synonym: Neut_0768

Alternate gene names: 114330781

Gene position: 785154-784264 (Counterclockwise)

Preceding gene: 114330787

Following gene: 114330780

Centisome position: 29.51

GC content: 46.91

Gene sequence:

>891_bases
ATGGGCAGCACTTTATTCAAAACAATCGCATTGATCGGGAAACACAAAAATCCCGATATCATGACGCCTCTGCTGAATCT
GGCAGAATATCTGACTGATCGGGGCACCAGCGTGGTACTGGATGATTTAACAGCCGCGCATATTGGCAAAAACCAATATC
CCGTAGTGGCTCTGGAAGAAATCGGCAGACAGGCTGATCTTGCAATTGTGCTGGGGGGAGATGGCACCATGCTTAATATT
GCTCGTACACTTGTTCCATTTAGTGTTCCGTTGATCGGTATCAATCAGGGCAGATTAGGATTTCTGACAGATCTTACAGT
CGATACCATGTATGCAACCCTGAATGACATGCTAGCGGGCCAATTTATTGTAGAGAACAGGATGCTGCTCACCACCGAAG
TCACACGTCATGGGGAAAGCGTCTTTAAAGAACTGGCTTTCAACGATGTAGTGCTTCATCGCGGCATCAGCAGTGGCATG
ATCGAGCTTGAGGTCCATATCAATGGAGAATATGTTTATTCTTTAAGATCAGATGGCCTCATTATTGCAACCCCTACCGG
ATCAACAGCCTATGCACTTTCCTCCGGTGGGCCGATCCTGCACCCAGGACTCAACCTGATGATATTGGTTCCTGTCTGTC
CGCATACACTTAGCAACCGTCCGATCGTAATCGGTGCAGATGCAGTCATTGAAATCAAAATTCATTATACAACTGAGACA
AAGATCTATACAGATAGCCATTCCTGGTTTGATCTGGGCGAGCATGACAGAGTACTGGTTCGGCGCTGTCCGGAAACAAT
AAAACTTCTGCATCCCGTCCATCACAGTTACTACCGTATGCTGCGGGAAAAACTCGGTTGGAGCAGCATCCTTCAGAAAA
ATAGCCGTTAG

Upstream 100 bases:

>100_bases
AGGCTACGGTAATATCCAGTACTTACAATCACTTGAATTCATCCTGATCACCTGCAGCAGGAATCCGGATATTTTTACTG
TTCCACCTCCCTTTTCATAC

Downstream 100 bases:

>100_bases
TATCCATCCATGTTGCAAAACCTATCTATTCAGAATTTCGTTATAGTTGATTACATTGATCTGCTCTTCAAACCCGGTTT
TACCGTTCTGACAGGTGAAA

Product: NAD(+)/NADH kinase family protein

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MGSTLFKTIALIGKHKNPDIMTPLLNLAEYLTDRGTSVVLDDLTAAHIGKNQYPVVALEEIGRQADLAIVLGGDGTMLNI
ARTLVPFSVPLIGINQGRLGFLTDLTVDTMYATLNDMLAGQFIVENRMLLTTEVTRHGESVFKELAFNDVVLHRGISSGM
IELEVHINGEYVYSLRSDGLIIATPTGSTAYALSSGGPILHPGLNLMILVPVCPHTLSNRPIVIGADAVIEIKIHYTTET
KIYTDSHSWFDLGEHDRVLVRRCPETIKLLHPVHHSYYRMLREKLGWSSILQKNSR

Sequences:

>Translated_296_residues
MGSTLFKTIALIGKHKNPDIMTPLLNLAEYLTDRGTSVVLDDLTAAHIGKNQYPVVALEEIGRQADLAIVLGGDGTMLNI
ARTLVPFSVPLIGINQGRLGFLTDLTVDTMYATLNDMLAGQFIVENRMLLTTEVTRHGESVFKELAFNDVVLHRGISSGM
IELEVHINGEYVYSLRSDGLIIATPTGSTAYALSSGGPILHPGLNLMILVPVCPHTLSNRPIVIGADAVIEIKIHYTTET
KIYTDSHSWFDLGEHDRVLVRRCPETIKLLHPVHHSYYRMLREKLGWSSILQKNSR
>Mature_295_residues
GSTLFKTIALIGKHKNPDIMTPLLNLAEYLTDRGTSVVLDDLTAAHIGKNQYPVVALEEIGRQADLAIVLGGDGTMLNIA
RTLVPFSVPLIGINQGRLGFLTDLTVDTMYATLNDMLAGQFIVENRMLLTTEVTRHGESVFKELAFNDVVLHRGISSGMI
ELEVHINGEYVYSLRSDGLIIATPTGSTAYALSSGGPILHPGLNLMILVPVCPHTLSNRPIVIGADAVIEIKIHYTTETK
IYTDSHSWFDLGEHDRVLVRRCPETIKLLHPVHHSYYRMLREKLGWSSILQKNSR

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family

Homologues:

Organism=Homo sapiens, GI55743112, Length=294, Percent_Identity=28.2312925170068, Blast_Score=99, Evalue=6e-21,
Organism=Escherichia coli, GI1788968, Length=287, Percent_Identity=43.9024390243902, Blast_Score=236, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6320794, Length=276, Percent_Identity=26.4492753623188, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6325068, Length=217, Percent_Identity=32.258064516129, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6322509, Length=247, Percent_Identity=27.5303643724696, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28573826, Length=281, Percent_Identity=28.1138790035587, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI161077047, Length=281, Percent_Identity=28.1138790035587, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI28573828, Length=281, Percent_Identity=28.1138790035587, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI28573832, Length=281, Percent_Identity=28.1138790035587, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI28573830, Length=281, Percent_Identity=28.1138790035587, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI281363323, Length=244, Percent_Identity=28.6885245901639, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281363321, Length=244, Percent_Identity=28.6885245901639, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20129957, Length=244, Percent_Identity=28.6885245901639, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24653422, Length=244, Percent_Identity=28.6885245901639, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24653424, Length=244, Percent_Identity=28.6885245901639, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPNK_NITEC (Q0AHZ4)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747003.1
- ProteinModelPortal:   Q0AHZ4
- SMR:   Q0AHZ4
- STRING:   Q0AHZ4
- GeneID:   4272992
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0768
- NMPDR:   fig|335283.3.peg.2385
- eggNOG:   COG0061
- HOGENOM:   HBG713904
- OMA:   FESFMID
- PhylomeDB:   Q0AHZ4
- ProtClustDB:   PRK02155
- BioCyc:   NEUT335283:NEUT_0768-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00361
- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504
- Gene3D:   G3DSA:2.60.200.30
- Gene3D:   G3DSA:3.40.50.10330
- PANTHER:   PTHR20275

Pfam domain/function: PF01513 NAD_kinase; SSF111331 ATP-NAD_kinase_PpnK-typ

EC number: =2.7.1.23

Molecular weight: Translated: 32706; Mature: 32575

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSTLFKTIALIGKHKNPDIMTPLLNLAEYLTDRGTSVVLDDLTAAHIGKNQYPVVALEE
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCCCCCEEEHHH
IGRQADLAIVLGGDGTMLNIARTLVPFSVPLIGINQGRLGFLTDLTVDTMYATLNDMLAG
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHC
QFIVENRMLLTTEVTRHGESVFKELAFNDVVLHRGISSGMIELEVHINGEYVYSLRSDGL
EEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEECCCCE
IIATPTGSTAYALSSGGPILHPGLNLMILVPVCPHTLSNRPIVIGADAVIEIKIHYTTET
EEEECCCCEEEEECCCCCEEECCCCEEEEEEECCCCCCCCCEEEECCEEEEEEEEEEECE
KIYTDSHSWFDLGEHDRVLVRRCPETIKLLHPVHHSYYRMLREKLGWSSILQKNSR
EEEECCCCEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
>Mature Secondary Structure 
GSTLFKTIALIGKHKNPDIMTPLLNLAEYLTDRGTSVVLDDLTAAHIGKNQYPVVALEE
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCCCCCEEEHHH
IGRQADLAIVLGGDGTMLNIARTLVPFSVPLIGINQGRLGFLTDLTVDTMYATLNDMLAG
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHC
QFIVENRMLLTTEVTRHGESVFKELAFNDVVLHRGISSGMIELEVHINGEYVYSLRSDGL
EEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEECCCCE
IIATPTGSTAYALSSGGPILHPGLNLMILVPVCPHTLSNRPIVIGADAVIEIKIHYTTET
EEEECCCCEEEEECCCCCEEECCCCEEEEEEECCCCCCCCCEEEECCEEEEEEEEEEECE
KIYTDSHSWFDLGEHDRVLVRRCPETIKLLHPVHHSYYRMLREKLGWSSILQKNSR
EEEECCCCEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA