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The map label for this gene is hxuC [H]

Identifier: 114330731

GI number: 114330731

Start: 722636

End: 724729

Strand: Reverse

Name: hxuC [H]

Synonym: Neut_0716

Alternate gene names: 114330731

Gene position: 724729-722636 (Counterclockwise)

Preceding gene: 114330732

Following gene: 114330728

Centisome position: 27.23

GC content: 50.14

Gene sequence:

>2094_bases
ATGTCACCGAGATGCAAGCATTATCCAGCCGCACTCAACATTTTTTATTTTGCAATCATCATGGCTGTATCGATGCTTTC
TAATGCTGTTCATGCACAGACAACATCAGCTGGCACAAAATCTGAAAGTAGGCTGGCTTCCGCTGACTTGAAGGAAATCA
CCGTTACCGCTACCCGCACCAGTCGAAAGGTAAGCGAAGTGCCCGAATCAGTCAGTGTGGTCGATACCGAGCAGATACGG
ACCCGGCAAGCAGCTGATATAGGAGATGTCCTCCGTTACCTGCCTAACGTTGAACTGGGTGGTGGGCCGCGCAATCTGGG
CCTTAGTCCGGTCATGCGCGGCATGGGGGATGATCGCATCCTGTTCCTGCTGGATGGTGCCAGACAGGATTTCAACCGTG
GTCACAATGCCCGCATCTTTACCGACCCTAGTCTGCTCAAGCGCGTGGATGTCATGCGCGGGCCGGCTTCCACCGTATGG
GGCAGTGGCGCGCTCGGTGGCGTTATCTCCTTAACCACGCTGGATGCAACCGATCTGCTGCGTTCCGGTGAGCGTTTCGG
CATGAAAGTTCGAGGGGGATTCCAGAGCATGAACGAGCAATATATTCCCGGCATCAGTGCTTACGGGCTGGTTGGAGAAC
AATTCGATTATCTGCTTGATTTTTCCTACCGTAATGCAGCCGACGATATCCGTCACGGCGACGGCTCCAAACTACAAAAC
TCCCGCTTTGAATCCTATGCCAGTCTGGCCAAATTTAACTGGACACCAGGCGATCATCGCTTCACATTTTCTGCACAAAC
GTTCGATCAGGCCGGTAAAGTACCTTCCAACCCGCAAGCCGCTTCTACGGCCAACACACTGGTAGATCGGGATACCGAGC
AGCGCAACTATACACTGCGCTATCGTTATGAAAATGTGGATAATGCCTGGCTCAATCCTGAAGTACTGGTCTACCACAAT
ACTACCTACAGTCTCGAGAAACGGTTATTTGACCGGCGGCGCGATGAAACTGATTTCTCCACGACCGGCATCAATGCACG
CAACAGCTCGCGCCTTGAGCTGAACAGTTTTACAACCCAATTAATTACCTATGGCGTTGATTATTTTCATAATGAAGCTA
AAGGCAAACGCAATGGCGCCACACGACCGGAATTCCCCCGGGGCGAAGCAGATGTCGTTGGCCTGTATTTGCAGGATGAA
ATCACGTTGTGGGAACGATTGTCACTCATTCCTGGTATACGTTGGGATTATTTCAGCAGTAAGGCAGATGGCATATCCGT
CAGCTCCAATCAAAATGATCGCGTCAATTTCAAGCTTGGTGGACTGCTTAAGGTAACTGAATGGTTCTCAATCACTGGTG
GCTACAGCGAAGCATTTCGCGCACCGACACTAGGCGAACTGTTTACGACCGGTACACATTTCACTTGTGGACCAAGGTGT
TCCAATCTGTTTACCCCCAATCCCGATCTTAAACCGGAAACTGCCTTCAATAAGGAAATTGGCGCACGCATACAAAAATC
GAATCTGCTGTTTGAAAACGATCAACTGACGATGCGCGGAACTTATTTCCATAATAAGGTTAAAAATTTCGTTGATCTGA
TGGTTGATTTTGTCTTTCGCCCGGTTCCTGGCAACCCAGGCAGAGGCGGCACCACAACCAGTGACAATGTACATGATGCC
CTGCTGAAAGGATTCGAAATAGAGACCAGCTATGCGGCGAAATATAGCTACACCGGCTTCTCCTACGCTCAGACCCGGGG
TCACAACCGGACGAGTGGCGGGGTATTGTCCAATGTTCAGCCAGATAAATGGATTGTAATGGCCGGGTTAAATTGGCCAA
CTCATGATCTTTCCCTGGGCTGGCGCAGCAGTATTGTCAGTGCACAACATCGTGTACCAACAGGTGGAACCCCGACACCT
GGCTATACACTGCATGATCTAACATTAACCTGGCTGCCACAAAACGGCCCGGCTAAAGGGTTACGTTTTGATTTTGGAAT
CGACAATCTGACTGACAAGGATTATCGCCGTCACCTCAACGTGTTGAAAGATCCGGGACGCAACTACAAACTGGCTGTTT
CATATCAATTCTGA

Upstream 100 bases:

>100_bases
CTAAAAACATTACCGTGGCAACAAAAACCGCTGTTCCAGCCAGCCAGCCAGCACTACGCCAGCCAGCCAGAAATTACTCA
TTTCTGGAGGAAGTATTTTT

Downstream 100 bases:

>100_bases
TTCGTGCTATCCAGCTTTGTTCATGTAGGGACTTGAATCTGAATTGTGTGGCAGGTTACAGCAGCTGTTCAATATCACTG
GCCGGTGATTCCGGCTTATC

Product: TonB-dependent heme/hemoglobin receptor family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 697; Mature: 696

Protein sequence:

>697_residues
MSPRCKHYPAALNIFYFAIIMAVSMLSNAVHAQTTSAGTKSESRLASADLKEITVTATRTSRKVSEVPESVSVVDTEQIR
TRQAADIGDVLRYLPNVELGGGPRNLGLSPVMRGMGDDRILFLLDGARQDFNRGHNARIFTDPSLLKRVDVMRGPASTVW
GSGALGGVISLTTLDATDLLRSGERFGMKVRGGFQSMNEQYIPGISAYGLVGEQFDYLLDFSYRNAADDIRHGDGSKLQN
SRFESYASLAKFNWTPGDHRFTFSAQTFDQAGKVPSNPQAASTANTLVDRDTEQRNYTLRYRYENVDNAWLNPEVLVYHN
TTYSLEKRLFDRRRDETDFSTTGINARNSSRLELNSFTTQLITYGVDYFHNEAKGKRNGATRPEFPRGEADVVGLYLQDE
ITLWERLSLIPGIRWDYFSSKADGISVSSNQNDRVNFKLGGLLKVTEWFSITGGYSEAFRAPTLGELFTTGTHFTCGPRC
SNLFTPNPDLKPETAFNKEIGARIQKSNLLFENDQLTMRGTYFHNKVKNFVDLMVDFVFRPVPGNPGRGGTTTSDNVHDA
LLKGFEIETSYAAKYSYTGFSYAQTRGHNRTSGGVLSNVQPDKWIVMAGLNWPTHDLSLGWRSSIVSAQHRVPTGGTPTP
GYTLHDLTLTWLPQNGPAKGLRFDFGIDNLTDKDYRRHLNVLKDPGRNYKLAVSYQF

Sequences:

>Translated_697_residues
MSPRCKHYPAALNIFYFAIIMAVSMLSNAVHAQTTSAGTKSESRLASADLKEITVTATRTSRKVSEVPESVSVVDTEQIR
TRQAADIGDVLRYLPNVELGGGPRNLGLSPVMRGMGDDRILFLLDGARQDFNRGHNARIFTDPSLLKRVDVMRGPASTVW
GSGALGGVISLTTLDATDLLRSGERFGMKVRGGFQSMNEQYIPGISAYGLVGEQFDYLLDFSYRNAADDIRHGDGSKLQN
SRFESYASLAKFNWTPGDHRFTFSAQTFDQAGKVPSNPQAASTANTLVDRDTEQRNYTLRYRYENVDNAWLNPEVLVYHN
TTYSLEKRLFDRRRDETDFSTTGINARNSSRLELNSFTTQLITYGVDYFHNEAKGKRNGATRPEFPRGEADVVGLYLQDE
ITLWERLSLIPGIRWDYFSSKADGISVSSNQNDRVNFKLGGLLKVTEWFSITGGYSEAFRAPTLGELFTTGTHFTCGPRC
SNLFTPNPDLKPETAFNKEIGARIQKSNLLFENDQLTMRGTYFHNKVKNFVDLMVDFVFRPVPGNPGRGGTTTSDNVHDA
LLKGFEIETSYAAKYSYTGFSYAQTRGHNRTSGGVLSNVQPDKWIVMAGLNWPTHDLSLGWRSSIVSAQHRVPTGGTPTP
GYTLHDLTLTWLPQNGPAKGLRFDFGIDNLTDKDYRRHLNVLKDPGRNYKLAVSYQF
>Mature_696_residues
SPRCKHYPAALNIFYFAIIMAVSMLSNAVHAQTTSAGTKSESRLASADLKEITVTATRTSRKVSEVPESVSVVDTEQIRT
RQAADIGDVLRYLPNVELGGGPRNLGLSPVMRGMGDDRILFLLDGARQDFNRGHNARIFTDPSLLKRVDVMRGPASTVWG
SGALGGVISLTTLDATDLLRSGERFGMKVRGGFQSMNEQYIPGISAYGLVGEQFDYLLDFSYRNAADDIRHGDGSKLQNS
RFESYASLAKFNWTPGDHRFTFSAQTFDQAGKVPSNPQAASTANTLVDRDTEQRNYTLRYRYENVDNAWLNPEVLVYHNT
TYSLEKRLFDRRRDETDFSTTGINARNSSRLELNSFTTQLITYGVDYFHNEAKGKRNGATRPEFPRGEADVVGLYLQDEI
TLWERLSLIPGIRWDYFSSKADGISVSSNQNDRVNFKLGGLLKVTEWFSITGGYSEAFRAPTLGELFTTGTHFTCGPRCS
NLFTPNPDLKPETAFNKEIGARIQKSNLLFENDQLTMRGTYFHNKVKNFVDLMVDFVFRPVPGNPGRGGTTTSDNVHDAL
LKGFEIETSYAAKYSYTGFSYAQTRGHNRTSGGVLSNVQPDKWIVMAGLNWPTHDLSLGWRSSIVSAQHRVPTGGTPTPG
YTLHDLTLTWLPQNGPAKGLRFDFGIDNLTDKDYRRHLNVLKDPGRNYKLAVSYQF

Specific function: Required for utilization of free heme at low concentrations [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=715, Percent_Identity=23.2167832167832, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1786798, Length=747, Percent_Identity=23.2931726907631, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790405, Length=160, Percent_Identity=32.5, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786344, Length=269, Percent_Identity=24.5353159851301, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR011276
- InterPro:   IPR010949
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 77845; Mature: 77714

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRCKHYPAALNIFYFAIIMAVSMLSNAVHAQTTSAGTKSESRLASADLKEITVTATRT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEEEEECCC
SRKVSEVPESVSVVDTEQIRTRQAADIGDVLRYLPNVELGGGPRNLGLSPVMRGMGDDRI
HHHHHHCCCCCEEEEHHHHHHHHHCCHHHHHHHCCCCEECCCCCCCCHHHHHHCCCCCEE
LFLLDGARQDFNRGHNARIFTDPSLLKRVDVMRGPASTVWGSGALGGVISLTTLDATDLL
EEEECCCHHHHCCCCCCEEEECHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHH
RSGERFGMKVRGGFQSMNEQYIPGISAYGLVGEQFDYLLDFSYRNAADDIRHGDGSKLQN
HCCHHCCEEEECCHHHCCHHCCCCCHHHCCCHHHHHHHEECCCCCCHHHHCCCCCCCHHH
SRFESYASLAKFNWTPGDHRFTFSAQTFDQAGKVPSNPQAASTANTLVDRDTEQRNYTLR
HHHHHHHHHHHCCCCCCCCEEEEEHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCEEE
YRYENVDNAWLNPEVLVYHNTTYSLEKRLFDRRRDETDFSTTGINARNSSRLELNSFTTQ
EEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHH
LITYGVDYFHNEAKGKRNGATRPEFPRGEADVVGLYLQDEITLWERLSLIPGIRWDYFSS
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCC
KADGISVSSNQNDRVNFKLGGLLKVTEWFSITGGYSEAFRAPTLGELFTTGTHFTCGPRC
CCCCEEECCCCCCEEEEEECCEEEEEEEEEECCCHHHHHCCCCHHHHHHCCCCEECCCCC
SNLFTPNPDLKPETAFNKEIGARIQKSNLLFENDQLTMRGTYFHNKVKNFVDLMVDFVFR
CCCCCCCCCCCCCCHHCHHHHCEEECCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHHEE
PVPGNPGRGGTTTSDNVHDALLKGFEIETSYAAKYSYTGFSYAQTRGHNRTSGGVLSNVQ
CCCCCCCCCCCCCCCCHHHHHHCCCEEECCEEEEEECCCCHHHHHCCCCCCCCCCCCCCC
PDKWIVMAGLNWPTHDLSLGWRSSIVSAQHRVPTGGTPTPGYTLHDLTLTWLPQNGPAKG
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCCC
LRFDFGIDNLTDKDYRRHLNVLKDPGRNYKLAVSYQF
CEEECCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECC
>Mature Secondary Structure 
SPRCKHYPAALNIFYFAIIMAVSMLSNAVHAQTTSAGTKSESRLASADLKEITVTATRT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEEEEECCC
SRKVSEVPESVSVVDTEQIRTRQAADIGDVLRYLPNVELGGGPRNLGLSPVMRGMGDDRI
HHHHHHCCCCCEEEEHHHHHHHHHCCHHHHHHHCCCCEECCCCCCCCHHHHHHCCCCCEE
LFLLDGARQDFNRGHNARIFTDPSLLKRVDVMRGPASTVWGSGALGGVISLTTLDATDLL
EEEECCCHHHHCCCCCCEEEECHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHH
RSGERFGMKVRGGFQSMNEQYIPGISAYGLVGEQFDYLLDFSYRNAADDIRHGDGSKLQN
HCCHHCCEEEECCHHHCCHHCCCCCHHHCCCHHHHHHHEECCCCCCHHHHCCCCCCCHHH
SRFESYASLAKFNWTPGDHRFTFSAQTFDQAGKVPSNPQAASTANTLVDRDTEQRNYTLR
HHHHHHHHHHHCCCCCCCCEEEEEHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCEEE
YRYENVDNAWLNPEVLVYHNTTYSLEKRLFDRRRDETDFSTTGINARNSSRLELNSFTTQ
EEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHH
LITYGVDYFHNEAKGKRNGATRPEFPRGEADVVGLYLQDEITLWERLSLIPGIRWDYFSS
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCC
KADGISVSSNQNDRVNFKLGGLLKVTEWFSITGGYSEAFRAPTLGELFTTGTHFTCGPRC
CCCCEEECCCCCCEEEEEECCEEEEEEEEEECCCHHHHHCCCCHHHHHHCCCCEECCCCC
SNLFTPNPDLKPETAFNKEIGARIQKSNLLFENDQLTMRGTYFHNKVKNFVDLMVDFVFR
CCCCCCCCCCCCCCHHCHHHHCEEECCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHHEE
PVPGNPGRGGTTTSDNVHDALLKGFEIETSYAAKYSYTGFSYAQTRGHNRTSGGVLSNVQ
CCCCCCCCCCCCCCCCHHHHHHCCCEEECCEEEEEECCCCHHHHHCCCCCCCCCCCCCCC
PDKWIVMAGLNWPTHDLSLGWRSSIVSAQHRVPTGGTPTPGYTLHDLTLTWLPQNGPAKG
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCCC
LRFDFGIDNLTDKDYRRHLNVLKDPGRNYKLAVSYQF
CEEECCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751272 [H]