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The map label for this gene is yacK [C]

Identifier: 114330725

GI number: 114330725

Start: 717225

End: 718217

Strand: Reverse

Name: yacK [C]

Synonym: Neut_0710

Alternate gene names: 114330725

Gene position: 718217-717225 (Counterclockwise)

Preceding gene: 114330726

Following gene: 114330721

Centisome position: 26.99

GC content: 48.84

Gene sequence:

>993_bases
ATGTATACAAAAAACAGCTATCCATTCTTATGGTCATATCCGATTTTGTTTGTTTTTCTGCTTCTGCTGGTGGCATCTTT
TTCAGTACAAGCCAGGGACACACAAGAGTACTGGATCGCCGCAGAAAAGACAGATTGGAATTATGCGCCATCTGGCGGAA
ATCTGATCAACCCCGAAAATGGTCTGGGTGTCTACGGAAACACATTGGTTTACACCAAATATCGCTATATCGGTTATACC
GACAACAGTTACTCTCAACCTATATCTCAGCCTGAATGGATGGGAATTCTAGGTCCCACCATCCGCGCAGTAGTGGGCGA
TATCATCAAGGTCCATTTTCTGAACAACACTGATCTGCCACTTTCAATACACCCTCATGGCGTGATGTATAACAAGGATA
ATGAAGGTGCTGATGGTGGTGCGGGCGGCAGTATTCCTCCGGGTGGACGCTACACTTATACCTGGGTCGTTGATCGGGAT
GCCGGCCCCGGTCCGGATGACCCCTCATCCATTGTCTGGCTCTATCACTCGCATGTCATGGCAGAACACGAAATCAACCT
GGGGTTAATCGGAACCATCATTGTCACCGCTGCTAATAAAGCGCGTTCGAATAGAGGCCCTATTCCACGCGATGTGGATC
AGGAGTTTATCGCGCTATACATGATATTCAACGAAGAAAATGATGAGGAAAGTGGCCTGAAACATACGATCAATGGCCGG
ATTTTCGGCAATCTGTCTGGCTTTGAAACTACACGTGGCCAGCGTGTTCGCTGGCATCTGATCGCACTGGGCAATGAAGT
GGATAACCACACAGTACATTGGCATGGGCAGACCGTGCTGGATAATGGTCGCCGAACTGACGTAATCGAGATCATGCCTG
CCAGCATGCGATCTGTTGACATGGTTCCCCGTTCACCAGGCAACTGGTTATTCCACTGCCACGTCAACGATCATATGATG
GCTGGAATGTCCACCCGCTGGCTGGTGAAATAG

Upstream 100 bases:

>100_bases
TTTTGAGATTGTGTTTAACGTAGTGAGGCAACACAGATCATTTTTCAGAGGATCCCTAACAGCGTCATGCATTGAGAGCA
AACTAAAAGAGAGTCCATCC

Downstream 100 bases:

>100_bases
TAGAAGGCTCCCGTTTTTACAGGGGGCCTTGAATCAGAATGATCCTGCGGGTAGATCAATTGAGCTTTTTCGATGCAAAG
TACCAGATCAGATATAAATA

Product: ferroxidase

Products: NA

Alternate protein names: Multicopper Oxidase Family Protein; Multicopper Oxidase

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MYTKNSYPFLWSYPILFVFLLLLVASFSVQARDTQEYWIAAEKTDWNYAPSGGNLINPENGLGVYGNTLVYTKYRYIGYT
DNSYSQPISQPEWMGILGPTIRAVVGDIIKVHFLNNTDLPLSIHPHGVMYNKDNEGADGGAGGSIPPGGRYTYTWVVDRD
AGPGPDDPSSIVWLYHSHVMAEHEINLGLIGTIIVTAANKARSNRGPIPRDVDQEFIALYMIFNEENDEESGLKHTINGR
IFGNLSGFETTRGQRVRWHLIALGNEVDNHTVHWHGQTVLDNGRRTDVIEIMPASMRSVDMVPRSPGNWLFHCHVNDHMM
AGMSTRWLVK

Sequences:

>Translated_330_residues
MYTKNSYPFLWSYPILFVFLLLLVASFSVQARDTQEYWIAAEKTDWNYAPSGGNLINPENGLGVYGNTLVYTKYRYIGYT
DNSYSQPISQPEWMGILGPTIRAVVGDIIKVHFLNNTDLPLSIHPHGVMYNKDNEGADGGAGGSIPPGGRYTYTWVVDRD
AGPGPDDPSSIVWLYHSHVMAEHEINLGLIGTIIVTAANKARSNRGPIPRDVDQEFIALYMIFNEENDEESGLKHTINGR
IFGNLSGFETTRGQRVRWHLIALGNEVDNHTVHWHGQTVLDNGRRTDVIEIMPASMRSVDMVPRSPGNWLFHCHVNDHMM
AGMSTRWLVK
>Mature_330_residues
MYTKNSYPFLWSYPILFVFLLLLVASFSVQARDTQEYWIAAEKTDWNYAPSGGNLINPENGLGVYGNTLVYTKYRYIGYT
DNSYSQPISQPEWMGILGPTIRAVVGDIIKVHFLNNTDLPLSIHPHGVMYNKDNEGADGGAGGSIPPGGRYTYTWVVDRD
AGPGPDDPSSIVWLYHSHVMAEHEINLGLIGTIIVTAANKARSNRGPIPRDVDQEFIALYMIFNEENDEESGLKHTINGR
IFGNLSGFETTRGQRVRWHLIALGNEVDNHTVHWHGQTVLDNGRRTDVIEIMPASMRSVDMVPRSPGNWLFHCHVNDHMM
AGMSTRWLVK

Specific function: Probable periplasmic copper oxidase [C]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI281485618, Length=359, Percent_Identity=36.7688022284123, Blast_Score=235, Evalue=3e-62,
Organism=Homo sapiens, GI195947365, Length=359, Percent_Identity=36.7688022284123, Blast_Score=235, Evalue=4e-62,
Organism=Homo sapiens, GI148886707, Length=359, Percent_Identity=34.2618384401114, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI4557485, Length=359, Percent_Identity=29.5264623955432, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI7662254, Length=338, Percent_Identity=34.0236686390533, Blast_Score=181, Evalue=9e-46,
Organism=Homo sapiens, GI105990535, Length=325, Percent_Identity=30.4615384615385, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI4503647, Length=341, Percent_Identity=29.3255131964809, Blast_Score=142, Evalue=5e-34,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 37107; Mature: 37107

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00079 MULTICOPPER_OXIDASE1 ; PS00080 MULTICOPPER_OXIDASE2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTKNSYPFLWSYPILFVFLLLLVASFSVQARDTQEYWIAAEKTDWNYAPSGGNLINPEN
CCCCCCCCEEEHHHHHHHHHHHHHHCCCEEECCCCEEEEEEECCCCCCCCCCCCCCCCCC
GLGVYGNTLVYTKYRYIGYTDNSYSQPISQPEWMGILGPTIRAVVGDIIKVHFLNNTDLP
CCEECCCEEEEEEEEEEEECCCCCCCCCCCCCCEEECCHHHHHHHCCEEEEEEECCCCCE
LSIHPHGVMYNKDNEGADGGAGGSIPPGGRYTYTWVVDRDAGPGPDDPSSIVWLYHSHVM
EEECCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEECEEE
AEHEINLGLIGTIIVTAANKARSNRGPIPRDVDQEFIALYMIFNEENDEESGLKHTINGR
EECCCCCEEEEEEEEEECHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEECCE
IFGNLSGFETTRGQRVRWHLIALGNEVDNHTVHWHGQTVLDNGRRTDVIEIMPASMRSVD
EEECCCCCCCCCCCEEEEEEEEECCCCCCCEEEECCCEEECCCCCCEEEEECCCCCCEEE
MVPRSPGNWLFHCHVNDHMMAGMSTRWLVK
CCCCCCCCEEEEEEECCCEECCCCEEEEEC
>Mature Secondary Structure
MYTKNSYPFLWSYPILFVFLLLLVASFSVQARDTQEYWIAAEKTDWNYAPSGGNLINPEN
CCCCCCCCEEEHHHHHHHHHHHHHHCCCEEECCCCEEEEEEECCCCCCCCCCCCCCCCCC
GLGVYGNTLVYTKYRYIGYTDNSYSQPISQPEWMGILGPTIRAVVGDIIKVHFLNNTDLP
CCEECCCEEEEEEEEEEEECCCCCCCCCCCCCCEEECCHHHHHHHCCEEEEEEECCCCCE
LSIHPHGVMYNKDNEGADGGAGGSIPPGGRYTYTWVVDRDAGPGPDDPSSIVWLYHSHVM
EEECCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEECEEE
AEHEINLGLIGTIIVTAANKARSNRGPIPRDVDQEFIALYMIFNEENDEESGLKHTINGR
EECCCCCEEEEEEEEEECHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEECCE
IFGNLSGFETTRGQRVRWHLIALGNEVDNHTVHWHGQTVLDNGRRTDVIEIMPASMRSVD
EEECCCCCCCCCCCEEEEEEEEECCCCCCCEEEECCCEEECCCCCCEEEEECCCCCCEEE
MVPRSPGNWLFHCHVNDHMMAGMSTRWLVK
CCCCCCCCEEEEEEECCCEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA