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The map label for this gene is lolE [C]

Identifier: 114330645

GI number: 114330645

Start: 641004

End: 642215

Strand: Reverse

Name: lolE [C]

Synonym: Neut_0630

Alternate gene names: 114330645

Gene position: 642215-641004 (Counterclockwise)

Preceding gene: 114330649

Following gene: 114330642

Centisome position: 24.13

GC content: 47.19

Gene sequence:

>1212_bases
ATGTTTAAACTTGCATTACGTAATATTTTTCGACAGAAAATACACACGCTTATGACGCTGGCTGCAGTCATCACCGGGGT
TACCGGTATCATTCTGGCTGGGGGGTGGATACAGGATATCTACGTGCAGTTGGGTGAAGCACTCATTCATTCACAAAGCG
GGCACTTACAGGTTTATCGCCAAGGATATTTTGCAGCCGGCTCACGCTCTCCAGAAAAGTTTTTAATGGATTTTCCTGAT
GCGCTTAAACAACACATCACCAGTCATCCAGAAATTAAGCAGGTGATGGCACGACTCAATTTTTCCGGCTTGCTGAATAA
TGGCAGGAGTGATTTGCCGATTATTGGTGAGGGTGTGGAGCCTGAGCTGGAAGCAGAATTGGGTAGTTCTGTACGTATCG
CAGCAGGACGGCAGCTAAATGACAGCGACACATTCGGCATTCTGTTGGGAAAGGGTGTCGCACAGGCACTACAGCTAAAA
CCGGGAGACCCCGTAACACTTCTGGTCAACACACTTGATGGGGCACTCAATAGCCTGGATTTTCAGGTAACTGGTATTTT
TCAGAGTTTCTCCAATGATTTTGATGCGCGCGCAGTCAGAATTCCCCTCGCTGCTGCACAAGAGTTGCTCGGCACCGGAG
GGGTTAATGCACTCGTTATTTCACTGCAACATACTGAAGAAACTGATCAGGTTGCGGCACAATTGAAGCAATGGCTGGAT
TCATCCGAGCTGGAAATCAAAACCTGGGTGGAACTGAATGATTTTTACGAAAAAACGGTGGAATTGTACAAGGGACAATT
TGGTGTGCTGCAGCTCATCATTCTGATTATGGTGCTGCTCAGTGTTGCCAACAGTGTCAATATGAGCATTTTCGAGCGTG
TCGGAGAATTCGGCACAATGATGGCCTTGGGAAATCGCAGTGATCAGGTATTCTGGTTGATCATCAGTGAAAATTTGCTG
CTGGGATTAATCGGTGGTGGCCTGGGGATTTATATGGGAATACTGCTGGCCATAATTATTTCCGCCATTGGTATCCCCAT
GCCCCCTCCTCCCAATGCAGATATTGGCTATATTGCTCACATCCAGATTGTACCTTCTGTTCTGCTACTGGCATTAGGTA
CTGGTTTTATTGCTACCGTGCTGGCGTCAATACTCCCAGCCAGGCATGTCTCACGCGTACCAGTCGTTGATGCGTTACGG
CAAAATATATAG

Upstream 100 bases:

>100_bases
GAAATGATCAGGACTTTATTACTGCTCTCAAACCAGTAACTATTCACTCTCTCCCAAAAAATGATGCTTGTCCTGACCCT
GACAACCTCTTCGTCGCACC

Downstream 100 bases:

>100_bases
GTGTAAAATTTTTTGACAATCAATTCCTGTTGCCACAACAAACCTTTTGCTTTGTGAACGCGAGGGATAAAAAATCCAGC
GTTGTCGTAACAATATGAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MFKLALRNIFRQKIHTLMTLAAVITGVTGIILAGGWIQDIYVQLGEALIHSQSGHLQVYRQGYFAAGSRSPEKFLMDFPD
ALKQHITSHPEIKQVMARLNFSGLLNNGRSDLPIIGEGVEPELEAELGSSVRIAAGRQLNDSDTFGILLGKGVAQALQLK
PGDPVTLLVNTLDGALNSLDFQVTGIFQSFSNDFDARAVRIPLAAAQELLGTGGVNALVISLQHTEETDQVAAQLKQWLD
SSELEIKTWVELNDFYEKTVELYKGQFGVLQLIILIMVLLSVANSVNMSIFERVGEFGTMMALGNRSDQVFWLIISENLL
LGLIGGGLGIYMGILLAIIISAIGIPMPPPPNADIGYIAHIQIVPSVLLLALGTGFIATVLASILPARHVSRVPVVDALR
QNI

Sequences:

>Translated_403_residues
MFKLALRNIFRQKIHTLMTLAAVITGVTGIILAGGWIQDIYVQLGEALIHSQSGHLQVYRQGYFAAGSRSPEKFLMDFPD
ALKQHITSHPEIKQVMARLNFSGLLNNGRSDLPIIGEGVEPELEAELGSSVRIAAGRQLNDSDTFGILLGKGVAQALQLK
PGDPVTLLVNTLDGALNSLDFQVTGIFQSFSNDFDARAVRIPLAAAQELLGTGGVNALVISLQHTEETDQVAAQLKQWLD
SSELEIKTWVELNDFYEKTVELYKGQFGVLQLIILIMVLLSVANSVNMSIFERVGEFGTMMALGNRSDQVFWLIISENLL
LGLIGGGLGIYMGILLAIIISAIGIPMPPPPNADIGYIAHIQIVPSVLLLALGTGFIATVLASILPARHVSRVPVVDALR
QNI
>Mature_403_residues
MFKLALRNIFRQKIHTLMTLAAVITGVTGIILAGGWIQDIYVQLGEALIHSQSGHLQVYRQGYFAAGSRSPEKFLMDFPD
ALKQHITSHPEIKQVMARLNFSGLLNNGRSDLPIIGEGVEPELEAELGSSVRIAAGRQLNDSDTFGILLGKGVAQALQLK
PGDPVTLLVNTLDGALNSLDFQVTGIFQSFSNDFDARAVRIPLAAAQELLGTGGVNALVISLQHTEETDQVAAQLKQWLD
SSELEIKTWVELNDFYEKTVELYKGQFGVLQLIILIMVLLSVANSVNMSIFERVGEFGTMMALGNRSDQVFWLIISENLL
LGLIGGGLGIYMGILLAIIISAIGIPMPPPPNADIGYIAHIQIVPSVLLLALGTGFIATVLASILPARHVSRVPVVDALR
QNI

Specific function: Part Of An ATP-Dependent Transport System Lolcde Responsible For The Release Of Lipoproteins Targeted To The Outer Membrane From The Inner Membrane. Such A Release Is Dependent Of The Sorting-Signal (Absence Of An Asp At Position 2 Of The Mature Lipoprot

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=268, Percent_Identity=22.7611940298507, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43624; Mature: 43624

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKLALRNIFRQKIHTLMTLAAVITGVTGIILAGGWIQDIYVQLGEALIHSQSGHLQVYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEE
QGYFAAGSRSPEKFLMDFPDALKQHITSHPEIKQVMARLNFSGLLNNGRSDLPIIGEGVE
CCEEECCCCCHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCHHHHHCCCCCCCCEECCCCC
PELEAELGSSVRIAAGRQLNDSDTFGILLGKGVAQALQLKPGDPVTLLVNTLDGALNSLD
CHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCC
FQVTGIFQSFSNDFDARAVRIPLAAAQELLGTGGVNALVISLQHTEETDQVAAQLKQWLD
EEEHHHHHHHCCCCCCCEEEECHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHCC
SSELEIKTWVELNDFYEKTVELYKGQFGVLQLIILIMVLLSVANSVNMSIFERVGEFGTM
CCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
MALGNRSDQVFWLIISENLLLGLIGGGLGIYMGILLAIIISAIGIPMPPPPNADIGYIAH
HHCCCCCCCEEEEEEECCEEEHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEH
IQIVPSVLLLALGTGFIATVLASILPARHVSRVPVVDALRQNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure
MFKLALRNIFRQKIHTLMTLAAVITGVTGIILAGGWIQDIYVQLGEALIHSQSGHLQVYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEE
QGYFAAGSRSPEKFLMDFPDALKQHITSHPEIKQVMARLNFSGLLNNGRSDLPIIGEGVE
CCEEECCCCCHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCHHHHHCCCCCCCCEECCCCC
PELEAELGSSVRIAAGRQLNDSDTFGILLGKGVAQALQLKPGDPVTLLVNTLDGALNSLD
CHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCC
FQVTGIFQSFSNDFDARAVRIPLAAAQELLGTGGVNALVISLQHTEETDQVAAQLKQWLD
EEEHHHHHHHCCCCCCCEEEECHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHCC
SSELEIKTWVELNDFYEKTVELYKGQFGVLQLIILIMVLLSVANSVNMSIFERVGEFGTM
CCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
MALGNRSDQVFWLIISENLLLGLIGGGLGIYMGILLAIIISAIGIPMPPPPNADIGYIAH
HHCCCCCCCEEEEEEECCEEEHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEH
IQIVPSVLLLALGTGFIATVLASILPARHVSRVPVVDALRQNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]