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The map label for this gene is aspS

Identifier: 114330631

GI number: 114330631

Start: 625782

End: 627563

Strand: Reverse

Name: aspS

Synonym: Neut_0616

Alternate gene names: 114330631

Gene position: 627563-625782 (Counterclockwise)

Preceding gene: 114330632

Following gene: 114330630

Centisome position: 23.58

GC content: 52.53

Gene sequence:

>1782_bases
ATGCGTACTGACTATTGCGGCGCCATCAACACACGTCATCTGGGTAGAACAATTACTTTATGCGGCTGGGTACATCGCCG
GCGTGATCATGGTGGGGTTATTTTTATTGACCTGCGCGACCGCGAGGGAATCGTTCAGATTGTTTGTGATCCTGATAATG
TTGCAGCTTTCCCGATTGCAGAAAAAATCCGTAATGAATTTGTGCTGGAAATTACCGGCCTGGTACGCCATCGTCCCGAG
GGGACAGTCAACCGGGGGATTCCCAGCGGGGAAATCGAAGTATTGGTCAGCACTATCGAAATTTTAAATCCTTCGCTCAC
TCCCCCGTTCCAGATGGATGATGACAATCTGAGCGAAGCGATACGATTGGAATACCGTTATCTGGATTTGCGCCGCCCGG
CGATGCAACACAACATCCGGTTGCGGCACAAGGTCACCATGGCGACACGCGTATTCCTGGATCAGCACGGCTTTATCGAC
GTGGAAACGCCAATGCTGACCAAATCCACGCCGGAAGGCGCGCGTGATTATCTGGTACCTTCGCGCGTCAACGTTGGCTG
TTTTTTTGCACTGCCACAATCTCCGCAACTGTTCAAGCAGCTACTGATGGTGTCCGGGTTCGATCGCTACTATCAGATTA
CCCGCTGCTTCCGGGACGAAGATCTGCGTGCAGACCGCCAGCCAGAATTTACCCAGATTGATATTGAAACCTCTTTTCTG
CAAGAAAATGACATCATGGATCTGATGGAGGACATGATCCGCCGCCTGTTTGCTGATGTGATCAATGTCAGCTTGCCCGA
CCCCTTCCCCCGGATCAGTTATGCTGACGCCATGTTCCGCTACGGATCAGACAAGCCAGATCTGCGGGTGCCACTGGAAC
TGACAGAGCTGACTGATCTGATGCAGGACGTACCTTTCCAGGTATTCCGCGATGCTGCACAAAAACCGGGTGGGCGAGTC
GCCGCACTACGTGTTCCTGGTGGTGGGGAGCTGTCCCGCAAGGAGATCGATGAGTACACCCGGTTTGTCGGCATTTACGG
AGCAAAAGGTCTGGCCTATATCAAGATTAATGACCTGACCAAAGGTATGGAGGGATTGCAATCCCCTATCCTGAAATTCC
TGCCCGAGCCTGTCGTGCAATCGATGCTCGAACGCACTCAGGCACAGAATGGTGATCTGGTATTTTTTGGTGCGGACAAG
GTCAAAACTGTTAACGATGCCTTGGGCGCATTACGGGTCAAAATCGGGCATGAACGCGGTCTGGCCACAAATTTGTGGCA
ACCTTTGTGGGTCGTGGATTTCCCAATGTTCGAGTGGGACGAAGAAGAAAAACGCTGGCAGGCCTTACATCACCCCTTCA
CCGCTCCCAGCCAGGGGCATGAGGATTTCCTGGCAACCGATCCGGGCAAGGCACTTTCCAGGGCATATGACATGGTATTG
AACGGCATGGAAATTGGCGGTGGGTCAATCCGTATTCACCGGCAGGATGTACAAAGCAAGGTATTCCAGGCATTGAACAT
AGCGGATGACGAAGCAAAACTGAAATTCGGCTTTCTGCTGGATGCCCTGCAATACGGCGCCCCACCGCATGGCGGCATAG
CCTTTGGTCTTGATCGTATCGTTGCCATGATGACCGGTACAGATTCTATCCGCGATGTGATTGCTTTCCCCAAAACACAA
CGCGCTCAATGTCTGCTGACGCAGGCACCCAGTACCGTCGAGGAGAAACAATTGCGGGAGCTGCATATCCGTCTGCGAAA
GACCGATATCACAACCGATTAG

Upstream 100 bases:

>100_bases
ACAACCACCGTGCCGTCTGCGCCTGCTACAGACTAGCAGGATTTTTACACAGCAAGGTTATCTGAACCGTTTTTTCATTC
AATCAACATTAACGTCACTT

Downstream 100 bases:

>100_bases
CTGGATTTGTCTGTTGCAAGTCTACAAAATACCCATATCTGTTCTGGTCGTTATCCACACGGTCGATCTGCGGGTGTTGC
TGTTGGAACGCGCTGACCAC

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MRTDYCGAINTRHLGRTITLCGWVHRRRDHGGVIFIDLRDREGIVQIVCDPDNVAAFPIAEKIRNEFVLEITGLVRHRPE
GTVNRGIPSGEIEVLVSTIEILNPSLTPPFQMDDDNLSEAIRLEYRYLDLRRPAMQHNIRLRHKVTMATRVFLDQHGFID
VETPMLTKSTPEGARDYLVPSRVNVGCFFALPQSPQLFKQLLMVSGFDRYYQITRCFRDEDLRADRQPEFTQIDIETSFL
QENDIMDLMEDMIRRLFADVINVSLPDPFPRISYADAMFRYGSDKPDLRVPLELTELTDLMQDVPFQVFRDAAQKPGGRV
AALRVPGGGELSRKEIDEYTRFVGIYGAKGLAYIKINDLTKGMEGLQSPILKFLPEPVVQSMLERTQAQNGDLVFFGADK
VKTVNDALGALRVKIGHERGLATNLWQPLWVVDFPMFEWDEEEKRWQALHHPFTAPSQGHEDFLATDPGKALSRAYDMVL
NGMEIGGGSIRIHRQDVQSKVFQALNIADDEAKLKFGFLLDALQYGAPPHGGIAFGLDRIVAMMTGTDSIRDVIAFPKTQ
RAQCLLTQAPSTVEEKQLRELHIRLRKTDITTD

Sequences:

>Translated_593_residues
MRTDYCGAINTRHLGRTITLCGWVHRRRDHGGVIFIDLRDREGIVQIVCDPDNVAAFPIAEKIRNEFVLEITGLVRHRPE
GTVNRGIPSGEIEVLVSTIEILNPSLTPPFQMDDDNLSEAIRLEYRYLDLRRPAMQHNIRLRHKVTMATRVFLDQHGFID
VETPMLTKSTPEGARDYLVPSRVNVGCFFALPQSPQLFKQLLMVSGFDRYYQITRCFRDEDLRADRQPEFTQIDIETSFL
QENDIMDLMEDMIRRLFADVINVSLPDPFPRISYADAMFRYGSDKPDLRVPLELTELTDLMQDVPFQVFRDAAQKPGGRV
AALRVPGGGELSRKEIDEYTRFVGIYGAKGLAYIKINDLTKGMEGLQSPILKFLPEPVVQSMLERTQAQNGDLVFFGADK
VKTVNDALGALRVKIGHERGLATNLWQPLWVVDFPMFEWDEEEKRWQALHHPFTAPSQGHEDFLATDPGKALSRAYDMVL
NGMEIGGGSIRIHRQDVQSKVFQALNIADDEAKLKFGFLLDALQYGAPPHGGIAFGLDRIVAMMTGTDSIRDVIAFPKTQ
RAQCLLTQAPSTVEEKQLRELHIRLRKTDITTD
>Mature_593_residues
MRTDYCGAINTRHLGRTITLCGWVHRRRDHGGVIFIDLRDREGIVQIVCDPDNVAAFPIAEKIRNEFVLEITGLVRHRPE
GTVNRGIPSGEIEVLVSTIEILNPSLTPPFQMDDDNLSEAIRLEYRYLDLRRPAMQHNIRLRHKVTMATRVFLDQHGFID
VETPMLTKSTPEGARDYLVPSRVNVGCFFALPQSPQLFKQLLMVSGFDRYYQITRCFRDEDLRADRQPEFTQIDIETSFL
QENDIMDLMEDMIRRLFADVINVSLPDPFPRISYADAMFRYGSDKPDLRVPLELTELTDLMQDVPFQVFRDAAQKPGGRV
AALRVPGGGELSRKEIDEYTRFVGIYGAKGLAYIKINDLTKGMEGLQSPILKFLPEPVVQSMLERTQAQNGDLVFFGADK
VKTVNDALGALRVKIGHERGLATNLWQPLWVVDFPMFEWDEEEKRWQALHHPFTAPSQGHEDFLATDPGKALSRAYDMVL
NGMEIGGGSIRIHRQDVQSKVFQALNIADDEAKLKFGFLLDALQYGAPPHGGIAFGLDRIVAMMTGTDSIRDVIAFPKTQ
RAQCLLTQAPSTVEEKQLRELHIRLRKTDITTD

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI40789249, Length=602, Percent_Identity=41.8604651162791, Blast_Score=450, Evalue=1e-126,
Organism=Homo sapiens, GI194272210, Length=243, Percent_Identity=26.3374485596708, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI5031815, Length=243, Percent_Identity=26.3374485596708, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI45439306, Length=317, Percent_Identity=26.813880126183, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1788173, Length=588, Percent_Identity=58.3333333333333, Blast_Score=717, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=268, Percent_Identity=25, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1789256, Length=276, Percent_Identity=23.9130434782609, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32566633, Length=604, Percent_Identity=36.4238410596026, Blast_Score=340, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI71994340, Length=295, Percent_Identity=24.406779661017, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17535925, Length=295, Percent_Identity=24.406779661017, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17535927, Length=295, Percent_Identity=24.406779661017, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71984122, Length=290, Percent_Identity=25.5172413793103, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17551876, Length=280, Percent_Identity=23.2142857142857, Blast_Score=76, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6325153, Length=632, Percent_Identity=33.2278481012658, Blast_Score=292, Evalue=9e-80,
Organism=Saccharomyces cerevisiae, GI6320242, Length=277, Percent_Identity=27.4368231046931, Blast_Score=88, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321807, Length=297, Percent_Identity=26.5993265993266, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6323011, Length=270, Percent_Identity=25.5555555555556, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24584738, Length=599, Percent_Identity=36.7278797996661, Blast_Score=360, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24640849, Length=243, Percent_Identity=28.3950617283951, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640851, Length=243, Percent_Identity=28.3950617283951, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17136276, Length=239, Percent_Identity=27.1966527196653, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI19921528, Length=280, Percent_Identity=25.7142857142857, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYD_NITEC (Q0AIE4)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746853.1
- ProteinModelPortal:   Q0AIE4
- SMR:   Q0AIE4
- STRING:   Q0AIE4
- GeneID:   4272511
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0616
- NMPDR:   fig|335283.3.peg.1489
- eggNOG:   COG0173
- HOGENOM:   HBG396032
- OMA:   AFPKTQQ
- PhylomeDB:   Q0AIE4
- ProtClustDB:   PRK00476
- BioCyc:   NEUT335283:NEUT_0616-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00044_B
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:3.30.1360.30
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF5
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00459

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 67312; Mature: 67312

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTDYCGAINTRHLGRTITLCGWVHRRRDHGGVIFIDLRDREGIVQIVCDPDNVAAFPIA
CCCCCCCCCCCHHCCCEEHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCEECHHH
EKIRNEFVLEITGLVRHRPEGTVNRGIPSGEIEVLVSTIEILNPSLTPPFQMDDDNLSEA
HHHHHHHEEEEHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
IRLEYRYLDLRRPAMQHNIRLRHKVTMATRVFLDQHGFIDVETPMLTKSTPEGARDYLVP
HHHHHHHHHHCCHHHHCCCEEEEEHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHCCCC
SRVNVGCFFALPQSPQLFKQLLMVSGFDRYYQITRCFRDEDLRADRQPEFTQIDIETSFL
CCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHH
QENDIMDLMEDMIRRLFADVINVSLPDPFPRISYADAMFRYGSDKPDLRVPLELTELTDL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCEEECEEHHHHHHH
MQDVPFQVFRDAAQKPGGRVAALRVPGGGELSRKEIDEYTRFVGIYGAKGLAYIKINDLT
HHHCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHEEECCCCEEEEEECCHH
KGMEGLQSPILKFLPEPVVQSMLERTQAQNGDLVFFGADKVKTVNDALGALRVKIGHERG
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHEEEEECCCCC
LATNLWQPLWVVDFPMFEWDEEEKRWQALHHPFTAPSQGHEDFLATDPGKALSRAYDMVL
CHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
NGMEIGGGSIRIHRQDVQSKVFQALNIADDEAKLKFGFLLDALQYGAPPHGGIAFGLDRI
CCEEECCCEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VAMMTGTDSIRDVIAFPKTQRAQCLLTQAPSTVEEKQLRELHIRLRKTDITTD
HHHHCCCHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHEECCCCCC
>Mature Secondary Structure
MRTDYCGAINTRHLGRTITLCGWVHRRRDHGGVIFIDLRDREGIVQIVCDPDNVAAFPIA
CCCCCCCCCCCHHCCCEEHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCEECHHH
EKIRNEFVLEITGLVRHRPEGTVNRGIPSGEIEVLVSTIEILNPSLTPPFQMDDDNLSEA
HHHHHHHEEEEHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
IRLEYRYLDLRRPAMQHNIRLRHKVTMATRVFLDQHGFIDVETPMLTKSTPEGARDYLVP
HHHHHHHHHHCCHHHHCCCEEEEEHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHCCCC
SRVNVGCFFALPQSPQLFKQLLMVSGFDRYYQITRCFRDEDLRADRQPEFTQIDIETSFL
CCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHH
QENDIMDLMEDMIRRLFADVINVSLPDPFPRISYADAMFRYGSDKPDLRVPLELTELTDL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCEEECEEHHHHHHH
MQDVPFQVFRDAAQKPGGRVAALRVPGGGELSRKEIDEYTRFVGIYGAKGLAYIKINDLT
HHHCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHEEECCCCEEEEEECCHH
KGMEGLQSPILKFLPEPVVQSMLERTQAQNGDLVFFGADKVKTVNDALGALRVKIGHERG
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHEEEEECCCCC
LATNLWQPLWVVDFPMFEWDEEEKRWQALHHPFTAPSQGHEDFLATDPGKALSRAYDMVL
CHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
NGMEIGGGSIRIHRQDVQSKVFQALNIADDEAKLKFGFLLDALQYGAPPHGGIAFGLDRI
CCEEECCCEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VAMMTGTDSIRDVIAFPKTQRAQCLLTQAPSTVEEKQLRELHIRLRKTDITTD
HHHHCCCHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA