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The map label for this gene is hslV

Identifier: 114330627

GI number: 114330627

Start: 623420

End: 623941

Strand: Reverse

Name: hslV

Synonym: Neut_0612

Alternate gene names: 114330627

Gene position: 623941-623420 (Counterclockwise)

Preceding gene: 114330628

Following gene: 114330626

Centisome position: 23.45

GC content: 56.32

Gene sequence:

>522_bases
ATGACCACGATAGTATCAGTCCGGCGCGGCCGGCAAGTAGCATTGGGTGGAGATGGCCAGGTCACGCTTGGCGCAGTCGT
TGCTAAAGCCAGTGCACGCAAGGTACGCAGGCTTTATCACGACAAGGTTCTTGCGGGATTTGCAGGCGGCACGGCCGATG
CATTCACGCTATTTGAACGCTTTGAAGCCAAACTGGAAAAACATCAGGGACATCTCTTGCGCTCTGCAGTCGAACTTGCC
AAGGACTGGCGTACTGACCGTATCCTGCGTCGCCTGGAAGCGATGCTGGTAGTGGCCGATCATGAAGCCACTCTCATCAT
CACAGGAGCAGGCGACGTCATTGAACCGGAACAAGGGCTAGCGGCTATCGGGAGTGGTGGCGCCTATGCGCAGGCGGCTG
CACGTGCACTGCTGGAAAATACTAATCTGGGCCCTGCCGAGACCGTTGCCAAGGCGCTGACCATCGCCGGTGATATCTGC
ATCTATACCAATCAGGTGCATGTCATTGAGCAGCTCGATTAA

Upstream 100 bases:

>100_bases
CTGCTTGAAGACAGCCCCTCTTCTGGCGACATCTGCACCCGTAACTGAATCTCGTTATAAAACGGCGTTATAATCGTTTT
TTTAGCCAAATACAAAAAAT

Downstream 100 bases:

>100_bases
CACCAGGAATTAATCCAAGCCAGGAAAACCTATCATGTCACATATGACGCCACAGGAAATTGTCCACGAACTGGACAAAC
ATATCATCGGGCAGGAAGCC

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MTTIVSVRRGRQVALGGDGQVTLGAVVAKASARKVRRLYHDKVLAGFAGGTADAFTLFERFEAKLEKHQGHLLRSAVELA
KDWRTDRILRRLEAMLVVADHEATLIITGAGDVIEPEQGLAAIGSGGAYAQAAARALLENTNLGPAETVAKALTIAGDIC
IYTNQVHVIEQLD

Sequences:

>Translated_173_residues
MTTIVSVRRGRQVALGGDGQVTLGAVVAKASARKVRRLYHDKVLAGFAGGTADAFTLFERFEAKLEKHQGHLLRSAVELA
KDWRTDRILRRLEAMLVVADHEATLIITGAGDVIEPEQGLAAIGSGGAYAQAAARALLENTNLGPAETVAKALTIAGDIC
IYTNQVHVIEQLD
>Mature_172_residues
TTIVSVRRGRQVALGGDGQVTLGAVVAKASARKVRRLYHDKVLAGFAGGTADAFTLFERFEAKLEKHQGHLLRSAVELAK
DWRTDRILRRLEAMLVVADHEATLIITGAGDVIEPEQGLAAIGSGGAYAQAAARALLENTNLGPAETVAKALTIAGDICI
YTNQVHVIEQLD

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=172, Percent_Identity=72.0930232558139, Blast_Score=253, Evalue=7e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_NITEC (Q0AD36)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746849.1
- ProteinModelPortal:   Q0AD36
- SMR:   Q0AD36
- STRING:   Q0AD36
- MEROPS:   T01.006
- GeneID:   4272506
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0612
- NMPDR:   fig|335283.3.peg.1485
- eggNOG:   COG5405
- HOGENOM:   HBG288822
- OMA:   AADICVY
- PhylomeDB:   Q0AD36
- ProtClustDB:   PRK05456
- BioCyc:   NEUT335283:NEUT_0612-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.- [C]

Molecular weight: Translated: 18441; Mature: 18310

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: ACT_SITE 2-2

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIVSVRRGRQVALGGDGQVTLGAVVAKASARKVRRLYHDKVLAGFAGGTADAFTLFER
CCCEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FEAKLEKHQGHLLRSAVELAKDWRTDRILRRLEAMLVVADHEATLIITGAGDVIEPEQGL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEECCCEEEEEECCCCCCCCCCCC
AAIGSGGAYAQAAARALLENTNLGPAETVAKALTIAGDICIYTNQVHVIEQLD
EEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCEEEEEECC
>Mature Secondary Structure 
TTIVSVRRGRQVALGGDGQVTLGAVVAKASARKVRRLYHDKVLAGFAGGTADAFTLFER
CCEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FEAKLEKHQGHLLRSAVELAKDWRTDRILRRLEAMLVVADHEATLIITGAGDVIEPEQGL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEECCCEEEEEECCCCCCCCCCCC
AAIGSGGAYAQAAARALLENTNLGPAETVAKALTIAGDICIYTNQVHVIEQLD
EEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA