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The map label for this gene is yfcB [C]

Identifier: 114330608

GI number: 114330608

Start: 600371

End: 601291

Strand: Reverse

Name: yfcB [C]

Synonym: Neut_0593

Alternate gene names: 114330608

Gene position: 601291-600371 (Counterclockwise)

Preceding gene: 114330612

Following gene: 114330601

Centisome position: 22.6

GC content: 47.67

Gene sequence:

>921_bases
ATGACTTATACCAGACAGCCCAATAACACTACCATCCTCCAGGCAGGGGAAGAATTGCGCACCTTGCGTGATTTGTTGCG
TTTTGCAGTAAGCTATTTCAACCGATCCGATCTTTTCCTGGGACACGGTCTGCCGACTGCTTATGATGAAGCAGCGCTTC
TGATTATGCACGCACTGTATCTGAACGCTGATCAGCTGGATCTTTTTATGGATGCCATGCTTACATACAATGAGCGTGAT
CAGGTTCTCCGTATCATTGAACGACGTGCCAGGGAAAAAATACCGGTTGCCTATCTGACGCACGAAGCCTGGCTGGGTGA
TTTTAATTTCTATGTTGATGAACGTGTCATCATACCGCGTTCATTTATTGCTGAATTGCTACATGATCGCCTGTCTCCCT
GGGTAATAGATCCACATGACATCAATTCAGCACTTGATTTATGCACTGGCTCCGGCTGTCTCGCCATTTTACTGGCACAC
GCCTTTGAGCAGGCACAAATCGATGCTGTGGATATTTCTTCCGATGCACTGGACGTGGCATCCATAAATATCAGAAATTA
TGATCTGATGAACCGGATCAACCTGATCCATGCGGATCTTTTCACCAGGCTGCAAGGTAAAAGATACGATCTAATCATCA
GTAATCCTCCCTATGTCAATGCTGTATCCATGGCAATGCTCCCTGAAGAATATCGCCACGAACCCGCTATCGCCCTGGCA
GGCGGACTTGATGGGCTGGATATTGTTCACCGAATTCTCAGAGAAGCAGCCGACCATCTGACCGAAAACGGCTTGCTGAT
CATGGAAATCGGCCACAATCAAGCCGAAATCGAGCAAGCATTTCCCCAGCTGTCCTGTACCTGGTTGGAAGCCAGTGCAG
GAGATCAGTTTCTTCTAATGGTGAGACGATGCGACTTGTAA

Upstream 100 bases:

>100_bases
ATGAAATACTCATCTTCTGCCTGAACCGGCACCCGGATAACCTGTACTTTCATCAGTTTTTTTATGCTAAATTGCTTTCC
GGAGAAACTCGGATTGAATC

Downstream 100 bases:

>100_bases
GCGTAGAAAGGAATTTGTCTGGAAGCGAGCTAACTGATCAGCGCCAGTAATCGTTCGACTTCTGTATCGACCAGCTCCAG
CCACATACCGCGCTTAAGTC

Product: N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTYTRQPNNTTILQAGEELRTLRDLLRFAVSYFNRSDLFLGHGLPTAYDEAALLIMHALYLNADQLDLFMDAMLTYNERD
QVLRIIERRAREKIPVAYLTHEAWLGDFNFYVDERVIIPRSFIAELLHDRLSPWVIDPHDINSALDLCTGSGCLAILLAH
AFEQAQIDAVDISSDALDVASINIRNYDLMNRINLIHADLFTRLQGKRYDLIISNPPYVNAVSMAMLPEEYRHEPAIALA
GGLDGLDIVHRILREAADHLTENGLLIMEIGHNQAEIEQAFPQLSCTWLEASAGDQFLLMVRRCDL

Sequences:

>Translated_306_residues
MTYTRQPNNTTILQAGEELRTLRDLLRFAVSYFNRSDLFLGHGLPTAYDEAALLIMHALYLNADQLDLFMDAMLTYNERD
QVLRIIERRAREKIPVAYLTHEAWLGDFNFYVDERVIIPRSFIAELLHDRLSPWVIDPHDINSALDLCTGSGCLAILLAH
AFEQAQIDAVDISSDALDVASINIRNYDLMNRINLIHADLFTRLQGKRYDLIISNPPYVNAVSMAMLPEEYRHEPAIALA
GGLDGLDIVHRILREAADHLTENGLLIMEIGHNQAEIEQAFPQLSCTWLEASAGDQFLLMVRRCDL
>Mature_305_residues
TYTRQPNNTTILQAGEELRTLRDLLRFAVSYFNRSDLFLGHGLPTAYDEAALLIMHALYLNADQLDLFMDAMLTYNERDQ
VLRIIERRAREKIPVAYLTHEAWLGDFNFYVDERVIIPRSFIAELLHDRLSPWVIDPHDINSALDLCTGSGCLAILLAHA
FEQAQIDAVDISSDALDVASINIRNYDLMNRINLIHADLFTRLQGKRYDLIISNPPYVNAVSMAMLPEEYRHEPAIALAG
GLDGLDIVHRILREAADHLTENGLLIMEIGHNQAEIEQAFPQLSCTWLEASAGDQFLLMVRRCDL

Specific function: Unknown

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705409, Length=270, Percent_Identity=27.7777777777778, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI87082085, Length=291, Percent_Identity=44.3298969072165, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI1787463, Length=258, Percent_Identity=29.8449612403101, Blast_Score=95, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24582226, Length=200, Percent_Identity=32, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR017127
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 34777; Mature: 34646

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYTRQPNNTTILQAGEELRTLRDLLRFAVSYFNRSDLFLGHGLPTAYDEAALLIMHALY
CCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHH
LNADQLDLFMDAMLTYNERDQVLRIIERRAREKIPVAYLTHEAWLGDFNFYVDERVIIPR
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCEEEECCEEECCH
SFIAELLHDRLSPWVIDPHDINSALDLCTGSGCLAILLAHAFEQAQIDAVDISSDALDVA
HHHHHHHHHHCCCCEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEECCCCCEEEE
SINIRNYDLMNRINLIHADLFTRLQGKRYDLIISNPPYVNAVSMAMLPEEYRHEPAIALA
EEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHCCHHHCCCCCEEEE
GGLDGLDIVHRILREAADHLTENGLLIMEIGHNQAEIEQAFPQLSCTWLEASAGDQFLLM
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCEEEEEECCCCCCEEEE
VRRCDL
EECCCC
>Mature Secondary Structure 
TYTRQPNNTTILQAGEELRTLRDLLRFAVSYFNRSDLFLGHGLPTAYDEAALLIMHALY
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHH
LNADQLDLFMDAMLTYNERDQVLRIIERRAREKIPVAYLTHEAWLGDFNFYVDERVIIPR
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCEEEECCEEECCH
SFIAELLHDRLSPWVIDPHDINSALDLCTGSGCLAILLAHAFEQAQIDAVDISSDALDVA
HHHHHHHHHHCCCCEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEECCCCCEEEE
SINIRNYDLMNRINLIHADLFTRLQGKRYDLIISNPPYVNAVSMAMLPEEYRHEPAIALA
EEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHCCHHHCCCCCEEEE
GGLDGLDIVHRILREAADHLTENGLLIMEIGHNQAEIEQAFPQLSCTWLEASAGDQFLLM
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCEEEEEECCCCCCEEEE
VRRCDL
EECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]