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The map label for this gene is fabD [H]

Identifier: 114330489

GI number: 114330489

Start: 484430

End: 485368

Strand: Reverse

Name: fabD [H]

Synonym: Neut_0469

Alternate gene names: 114330489

Gene position: 485368-484430 (Counterclockwise)

Preceding gene: 114330490

Following gene: 114330488

Centisome position: 18.24

GC content: 48.35

Gene sequence:

>939_bases
ATGAAGATTGCTTTTATTTTTCCCGGGCAGGGATCTCAGTCAGTCGGTATGATGGATGGTTATTCAGAACTTCCATCAAT
ACGTGAGACGTTCAATGAAGCATCAGATATTCTGCAACAGGATCTGTGGTCGTTAGCCAGTAACGGACCAGCAGACACTT
TGAATCTCACAACCAATACCCAGCCTGTCATGTTAACCGCTGACGTGGCCATCTACCGTGCATGGCAGCAGGCAGGAGGT
ACCCAACCACATTATCTGGCCGGTCATAGTCTTGGCGAATATGCTGCGCTGGTAGCTGCCGAATCGCTTAGTTTGGGTGA
TGCCCTGAAATTGGTTCGTCATCGCGCAGAAGTCATGCAAGAAACTGTTCCCGAAGGAACAGGAGGCATGGCAGCCATTG
TCGGGCTGGATAATGACACCATTTCTTCAGTATGCGCTGAAGTAATAAATATGCTGCCAGATACATCACTGGAACCAGCG
AACTTCAATGCCCCAGGCCAGGTCGTCATCGCTGGCCATTCTCAGGCAATTGCACAAGCAGTAACACTCGCAAAATCAAA
AGGAGCAAAACTGGCGGTTATACTGCCAATGAGTATTCCTTCACACTGCTCACTCATGCAACCAGCAGCCGAGAAATTTG
CACTTCTGCTGGAAAAAATCACATTCCAACCTCCCCGGATTCCTGTTTTGCACAACGTCGATGTCCAGCAGCACCCAGAA
ATAGCTTCTATTCGTGAGATACTTGCGCACCAGCTCGATAATCCGGTTCGCTGGACAGAGACAATTCAAGCCCTTGCGGG
ACTAGGTGTAAGACATGTTGTGGAGTGTGGTCCAGGCAAAGTGTTATCCGGACTGACGCGACGCATTGATAAGAATCTGG
AGAATATTGCACTAACTGATTCTAACTCCTTTCTCAAAACGGTAGGAACGTTGAAATAG

Upstream 100 bases:

>100_bases
GGCAGTTCGAGACGGGCGTGTCCAGTCAGGCCAGCATGTTGTGCTGGAAGGTGTGGGAGGTGGATTCACCTGGGGATCAG
TTCTGGTACGCTGGTAAAAC

Downstream 100 bases:

>100_bases
TACGTCAGTAATACATCATTAGAAATAACCCTTCCATCAATTCATAAACTCTCGGAATGATACTGGAACATAAAATTACA
CTGGTAACAGGAGCGAGTCG

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKIAFIFPGQGSQSVGMMDGYSELPSIRETFNEASDILQQDLWSLASNGPADTLNLTTNTQPVMLTADVAIYRAWQQAGG
TQPHYLAGHSLGEYAALVAAESLSLGDALKLVRHRAEVMQETVPEGTGGMAAIVGLDNDTISSVCAEVINMLPDTSLEPA
NFNAPGQVVIAGHSQAIAQAVTLAKSKGAKLAVILPMSIPSHCSLMQPAAEKFALLLEKITFQPPRIPVLHNVDVQQHPE
IASIREILAHQLDNPVRWTETIQALAGLGVRHVVECGPGKVLSGLTRRIDKNLENIALTDSNSFLKTVGTLK

Sequences:

>Translated_312_residues
MKIAFIFPGQGSQSVGMMDGYSELPSIRETFNEASDILQQDLWSLASNGPADTLNLTTNTQPVMLTADVAIYRAWQQAGG
TQPHYLAGHSLGEYAALVAAESLSLGDALKLVRHRAEVMQETVPEGTGGMAAIVGLDNDTISSVCAEVINMLPDTSLEPA
NFNAPGQVVIAGHSQAIAQAVTLAKSKGAKLAVILPMSIPSHCSLMQPAAEKFALLLEKITFQPPRIPVLHNVDVQQHPE
IASIREILAHQLDNPVRWTETIQALAGLGVRHVVECGPGKVLSGLTRRIDKNLENIALTDSNSFLKTVGTLK
>Mature_312_residues
MKIAFIFPGQGSQSVGMMDGYSELPSIRETFNEASDILQQDLWSLASNGPADTLNLTTNTQPVMLTADVAIYRAWQQAGG
TQPHYLAGHSLGEYAALVAAESLSLGDALKLVRHRAEVMQETVPEGTGGMAAIVGLDNDTISSVCAEVINMLPDTSLEPA
NFNAPGQVVIAGHSQAIAQAVTLAKSKGAKLAVILPMSIPSHCSLMQPAAEKFALLLEKITFQPPRIPVLHNVDVQQHPE
IASIREILAHQLDNPVRWTETIQALAGLGVRHVVECGPGKVLSGLTRRIDKNLENIALTDSNSFLKTVGTLK

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=30.8970099667774, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=37.6146788990826, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787334, Length=304, Percent_Identity=51.9736842105263, Blast_Score=310, Evalue=9e-86,
Organism=Caenorhabditis elegans, GI71984332, Length=271, Percent_Identity=28.7822878228782, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=299, Percent_Identity=27.4247491638796, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=31.2292358803987, Blast_Score=133, Evalue=1e-31,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33326; Mature: 33326

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAFIFPGQGSQSVGMMDGYSELPSIRETFNEASDILQQDLWSLASNGPADTLNLTTNT
CEEEEEECCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
QPVMLTADVAIYRAWQQAGGTQPHYLAGHSLGEYAALVAAESLSLGDALKLVRHRAEVMQ
CCEEEEHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ETVPEGTGGMAAIVGLDNDTISSVCAEVINMLPDTSLEPANFNAPGQVVIAGHSQAIAQA
HHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCHHHHHHH
VTLAKSKGAKLAVILPMSIPSHCSLMQPAAEKFALLLEKITFQPPRIPVLHNVDVQQHPE
HHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCC
IASIREILAHQLDNPVRWTETIQALAGLGVRHVVECGPGKVLSGLTRRIDKNLENIALTD
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHCCHHHEEEEC
SNSFLKTVGTLK
CCHHHHHHCCCC
>Mature Secondary Structure
MKIAFIFPGQGSQSVGMMDGYSELPSIRETFNEASDILQQDLWSLASNGPADTLNLTTNT
CEEEEEECCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
QPVMLTADVAIYRAWQQAGGTQPHYLAGHSLGEYAALVAAESLSLGDALKLVRHRAEVMQ
CCEEEEHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ETVPEGTGGMAAIVGLDNDTISSVCAEVINMLPDTSLEPANFNAPGQVVIAGHSQAIAQA
HHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCHHHHHHH
VTLAKSKGAKLAVILPMSIPSHCSLMQPAAEKFALLLEKITFQPPRIPVLHNVDVQQHPE
HHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCC
IASIREILAHQLDNPVRWTETIQALAGLGVRHVVECGPGKVLSGLTRRIDKNLENIALTD
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHCCHHHEEEEC
SNSFLKTVGTLK
CCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]