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The map label for this gene is ntrY [H]

Identifier: 114330409

GI number: 114330409

Start: 392936

End: 395110

Strand: Reverse

Name: ntrY [H]

Synonym: Neut_0388

Alternate gene names: 114330409

Gene position: 395110-392936 (Counterclockwise)

Preceding gene: 114330410

Following gene: 114330408

Centisome position: 14.85

GC content: 48.92

Gene sequence:

>2175_bases
ATGAAATACGTTATTTTCGTTGTCGCAGGATTAAGTACCATTATGCTATTCCTGCTGGCCTCAGCCGGAGCCAATACCGA
ATTTTTTGAACGCCATTACCGCTGGCTGATTGTCAGCATCGTAATTTTTCTGCTGCTCTTGATTGGAATCGTTGGATTTC
TACTCGGACGATTACGGCGCAGACTCAAGACTGGTGTATTCGGTTCAAAGTTGGCACTGCGGCTTCTGATGGTTTTTTCC
CTGATGGCCATTCTGCCCGGCGCGCTGGTGTATGGTATTTCAGTACAGTTTCTGGGAAAAAGTATTGAATCCTGGTTTGA
TGTCAAAGTGGATCGCGCACTGGAAGGTGGACTAACGCTGGGGCAAACGATACTGGATAACCTGCTGGAGGAATTGCAGA
AAAAGGCGCGGGCCGCCGCAATTGATCTGGCTGAACCGTCATCATTTCCTTTGACCGTTTTGAATCAGCTTCTAATTCAA
TCACAAATACAGGAAGCTACCCTGTTCAACCAGGATGGAAAGGTCATCGCCTTTACCGGTTTGGATGATACCGTATTGTT
TCCCGAAATCCCCAATACAGAAGCGATGCGGCGCATCCGGATGCAGAGGGATTACAGTGCGGTCGAAACACTCGCGAATA
ACACGCTGTATCTGCGAGTACTTGTTCCAGTCAACATACTAAGCGCCAACGAAGATATCCGAGTACTACAGGTACTGCAA
CGGGTGCCGCAATCCATCGCACACAACGCGGAAATCGTTCAGGCTGGCTTTAGTGATTATCAGGAATTAATGCTGTCTCG
TCAGGGATTGACTCGGCTGTACAGCGTAACATTGACCCTGGCCTTGTTGCTTGCTCTGTTTTCCGCACTGGCCGGTGCAT
TTCTGATCAGCGAAAAATTAAGCGCGCCACTGGGGTCATTGGCAGAAGGAACACGCGCCGTAGCTCAGGGTGATTTCAGC
CGGCGACACCAGATTCACAGTACCGATGAATTCGGTATCTTGACTGAATCATTCAATCTCATGACTGAACAACTGGAGGC
CGCACGCACCATCGCACAGCAGCATCAACAGGAAATTGAAAATGCACGTGCCTATCTCGAAAATATTCTGGCCAATCTGT
CATCAGGTGTTATCGTCTTTGATAAAGTATTGAGAATACGTGCAGTCAATCAGAGTGCAGAGCAAATACTGCAAATTCCG
CTGACCAATTTCGAGGGATTAACCATAGAAGAATGCGCCAAACAGGAAGCGGGATTGCGGTTATTGGCCGGGGAAATAAG
AAGCGGCTTTGATTCTGAAGAGGTTGGTGAATGGCAAAGACAAGTATTGCACTTCAATGCAGATAAGGAGCAGGTGCTGC
TTCTGCGAGGCTCTCGCCTACCCCAGGCATCCGGTGGCGGTGTTGTGGTATTCGACGACATCACCAGCCTGTTACAAGTC
CAGCGTACCGTAGCATGGGGAGAAGTAGCACGACGCCTGGCGCATGAGATTAAAAATCCACTTACGCCGATCCAGTTATC
CGCTGAGCGTTTGCAGCATAAGCTGATCAGCAAACTCGACGAGCCAGATGCCAGAATTCTGAAGCGTTCTACAGAAACAA
TCGTGAATCAGGTTGAAGCCCTGAAAAAAATGGTGAACGAATTCCGGGAATACGCACGAGTACCTGAACCCGAGTTATAC
CAGGTAGATATCAACCGGCTGGTACGGGAGATTCTGGCGCTTTATCAGACGACTGACAACACAGAAAACGAATCACCACT
GCCGCCAATCACGATAGAACTAGCAGGAGAGCTTGCCCCTGTCAGAGGAGATCCGGCGAGGTTGCGTCAAGTCATTCACA
ACTTGCTGCAGAACGCGCAAGATGCACTGGCCAATATAAAAGAAGCTGCTATTACTGTGCGGACCAGATCCGTTAATAAC
GGAATCGAGCTGAGTGTGACTGATAATGGCAAAGGATTCCCGGAGCAGGTCAAAACACATGTATTTGAGCCCTATGTCAC
CACCAAACCAAGAGGTACCGGGCTCGGGTTGCCGATTGTCAAAAAAATTGTGGATGAGCACGGTGGCACTGTCAAAATAC
AAAATATTCAGCCGCATGGTGCACAGGTTTCAATCATTCTGCCTGCATTCCTCCACAACAGTTCGCATGTTTCATCTGAG
GCAGCTCATGCCTGA

Upstream 100 bases:

>100_bases
TCAGGACTGGAATCTCATTTCTGAAAAAAAAATCTGGCAGGTTACATTTCCGCCTACCCCTGAAGCTGACAACGAATCTG
ATTATCGTTAGAGCCCGTTT

Downstream 100 bases:

>100_bases
GATGCTCAGTGATCCAATTGCAGATTGCAAAGTAAATCAGTTGGCATTTTCACAAAATTTTGCACAGGCAAAACATGCAA
GGCACAATATAGAGATAACT

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 724; Mature: 724

Protein sequence:

>724_residues
MKYVIFVVAGLSTIMLFLLASAGANTEFFERHYRWLIVSIVIFLLLLIGIVGFLLGRLRRRLKTGVFGSKLALRLLMVFS
LMAILPGALVYGISVQFLGKSIESWFDVKVDRALEGGLTLGQTILDNLLEELQKKARAAAIDLAEPSSFPLTVLNQLLIQ
SQIQEATLFNQDGKVIAFTGLDDTVLFPEIPNTEAMRRIRMQRDYSAVETLANNTLYLRVLVPVNILSANEDIRVLQVLQ
RVPQSIAHNAEIVQAGFSDYQELMLSRQGLTRLYSVTLTLALLLALFSALAGAFLISEKLSAPLGSLAEGTRAVAQGDFS
RRHQIHSTDEFGILTESFNLMTEQLEAARTIAQQHQQEIENARAYLENILANLSSGVIVFDKVLRIRAVNQSAEQILQIP
LTNFEGLTIEECAKQEAGLRLLAGEIRSGFDSEEVGEWQRQVLHFNADKEQVLLLRGSRLPQASGGGVVVFDDITSLLQV
QRTVAWGEVARRLAHEIKNPLTPIQLSAERLQHKLISKLDEPDARILKRSTETIVNQVEALKKMVNEFREYARVPEPELY
QVDINRLVREILALYQTTDNTENESPLPPITIELAGELAPVRGDPARLRQVIHNLLQNAQDALANIKEAAITVRTRSVNN
GIELSVTDNGKGFPEQVKTHVFEPYVTTKPRGTGLGLPIVKKIVDEHGGTVKIQNIQPHGAQVSIILPAFLHNSSHVSSE
AAHA

Sequences:

>Translated_724_residues
MKYVIFVVAGLSTIMLFLLASAGANTEFFERHYRWLIVSIVIFLLLLIGIVGFLLGRLRRRLKTGVFGSKLALRLLMVFS
LMAILPGALVYGISVQFLGKSIESWFDVKVDRALEGGLTLGQTILDNLLEELQKKARAAAIDLAEPSSFPLTVLNQLLIQ
SQIQEATLFNQDGKVIAFTGLDDTVLFPEIPNTEAMRRIRMQRDYSAVETLANNTLYLRVLVPVNILSANEDIRVLQVLQ
RVPQSIAHNAEIVQAGFSDYQELMLSRQGLTRLYSVTLTLALLLALFSALAGAFLISEKLSAPLGSLAEGTRAVAQGDFS
RRHQIHSTDEFGILTESFNLMTEQLEAARTIAQQHQQEIENARAYLENILANLSSGVIVFDKVLRIRAVNQSAEQILQIP
LTNFEGLTIEECAKQEAGLRLLAGEIRSGFDSEEVGEWQRQVLHFNADKEQVLLLRGSRLPQASGGGVVVFDDITSLLQV
QRTVAWGEVARRLAHEIKNPLTPIQLSAERLQHKLISKLDEPDARILKRSTETIVNQVEALKKMVNEFREYARVPEPELY
QVDINRLVREILALYQTTDNTENESPLPPITIELAGELAPVRGDPARLRQVIHNLLQNAQDALANIKEAAITVRTRSVNN
GIELSVTDNGKGFPEQVKTHVFEPYVTTKPRGTGLGLPIVKKIVDEHGGTVKIQNIQPHGAQVSIILPAFLHNSSHVSSE
AAHA
>Mature_724_residues
MKYVIFVVAGLSTIMLFLLASAGANTEFFERHYRWLIVSIVIFLLLLIGIVGFLLGRLRRRLKTGVFGSKLALRLLMVFS
LMAILPGALVYGISVQFLGKSIESWFDVKVDRALEGGLTLGQTILDNLLEELQKKARAAAIDLAEPSSFPLTVLNQLLIQ
SQIQEATLFNQDGKVIAFTGLDDTVLFPEIPNTEAMRRIRMQRDYSAVETLANNTLYLRVLVPVNILSANEDIRVLQVLQ
RVPQSIAHNAEIVQAGFSDYQELMLSRQGLTRLYSVTLTLALLLALFSALAGAFLISEKLSAPLGSLAEGTRAVAQGDFS
RRHQIHSTDEFGILTESFNLMTEQLEAARTIAQQHQQEIENARAYLENILANLSSGVIVFDKVLRIRAVNQSAEQILQIP
LTNFEGLTIEECAKQEAGLRLLAGEIRSGFDSEEVGEWQRQVLHFNADKEQVLLLRGSRLPQASGGGVVVFDDITSLLQV
QRTVAWGEVARRLAHEIKNPLTPIQLSAERLQHKLISKLDEPDARILKRSTETIVNQVEALKKMVNEFREYARVPEPELY
QVDINRLVREILALYQTTDNTENESPLPPITIELAGELAPVRGDPARLRQVIHNLLQNAQDALANIKEAAITVRTRSVNN
GIELSVTDNGKGFPEQVKTHVFEPYVTTKPRGTGLGLPIVKKIVDEHGGTVKIQNIQPHGAQVSIILPAFLHNSSHVSSE
AAHA

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=426, Percent_Identity=26.2910798122066, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=30.8695652173913, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790300, Length=367, Percent_Identity=25.8855585831063, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789808, Length=234, Percent_Identity=25.6410256410256, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=260, Percent_Identity=27.3076923076923, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786600, Length=264, Percent_Identity=25.7575757575758, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1790861, Length=223, Percent_Identity=28.2511210762332, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI145693157, Length=236, Percent_Identity=25.4237288135593, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1786912, Length=223, Percent_Identity=29.1479820627803, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80278; Mature: 80278

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYVIFVVAGLSTIMLFLLASAGANTEFFERHYRWLIVSIVIFLLLLIGIVGFLLGRLRR
CCEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLKTGVFGSKLALRLLMVFSLMAILPGALVYGISVQFLGKSIESWFDVKVDRALEGGLTL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
GQTILDNLLEELQKKARAAAIDLAEPSSFPLTVLNQLLIQSQIQEATLFNQDGKVIAFTG
HHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
LDDTVLFPEIPNTEAMRRIRMQRDYSAVETLANNTLYLRVLVPVNILSANEDIRVLQVLQ
CCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCHHHHHHHH
RVPQSIAHNAEIVQAGFSDYQELMLSRQGLTRLYSVTLTLALLLALFSALAGAFLISEKL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAPLGSLAEGTRAVAQGDFSRRHQIHSTDEFGILTESFNLMTEQLEAARTIAQQHQQEIE
CCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NARAYLENILANLSSGVIVFDKVLRIRAVNQSAEQILQIPLTNFEGLTIEECAKQEAGLR
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHH
LLAGEIRSGFDSEEVGEWQRQVLHFNADKEQVLLLRGSRLPQASGGGVVVFDDITSLLQV
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEHHHHHHHHHH
QRTVAWGEVARRLAHEIKNPLTPIQLSAERLQHKLISKLDEPDARILKRSTETIVNQVEA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LKKMVNEFREYARVPEPELYQVDINRLVREILALYQTTDNTENESPLPPITIELAGELAP
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCC
VRGDPARLRQVIHNLLQNAQDALANIKEAAITVRTRSVNNGIELSVTDNGKGFPEQVKTH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCCCHHHHHHH
VFEPYVTTKPRGTGLGLPIVKKIVDEHGGTVKIQNIQPHGAQVSIILPAFLHNSSHVSSE
HCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEHHHHCCCCCCCCC
AAHA
CCCC
>Mature Secondary Structure
MKYVIFVVAGLSTIMLFLLASAGANTEFFERHYRWLIVSIVIFLLLLIGIVGFLLGRLRR
CCEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLKTGVFGSKLALRLLMVFSLMAILPGALVYGISVQFLGKSIESWFDVKVDRALEGGLTL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
GQTILDNLLEELQKKARAAAIDLAEPSSFPLTVLNQLLIQSQIQEATLFNQDGKVIAFTG
HHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
LDDTVLFPEIPNTEAMRRIRMQRDYSAVETLANNTLYLRVLVPVNILSANEDIRVLQVLQ
CCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCHHHHHHHH
RVPQSIAHNAEIVQAGFSDYQELMLSRQGLTRLYSVTLTLALLLALFSALAGAFLISEKL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAPLGSLAEGTRAVAQGDFSRRHQIHSTDEFGILTESFNLMTEQLEAARTIAQQHQQEIE
CCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NARAYLENILANLSSGVIVFDKVLRIRAVNQSAEQILQIPLTNFEGLTIEECAKQEAGLR
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHH
LLAGEIRSGFDSEEVGEWQRQVLHFNADKEQVLLLRGSRLPQASGGGVVVFDDITSLLQV
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEHHHHHHHHHH
QRTVAWGEVARRLAHEIKNPLTPIQLSAERLQHKLISKLDEPDARILKRSTETIVNQVEA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LKKMVNEFREYARVPEPELYQVDINRLVREILALYQTTDNTENESPLPPITIELAGELAP
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCC
VRGDPARLRQVIHNLLQNAQDALANIKEAAITVRTRSVNNGIELSVTDNGKGFPEQVKTH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCCCHHHHHHH
VFEPYVTTKPRGTGLGLPIVKKIVDEHGGTVKIQNIQPHGAQVSIILPAFLHNSSHVSSE
HCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEHHHHCCCCCCCCC
AAHA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]