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The map label for this gene is bfrD [H]

Identifier: 114330397

GI number: 114330397

Start: 375433

End: 377643

Strand: Reverse

Name: bfrD [H]

Synonym: Neut_0374

Alternate gene names: 114330397

Gene position: 377643-375433 (Counterclockwise)

Preceding gene: 114330400

Following gene: 114330396

Centisome position: 14.19

GC content: 50.97

Gene sequence:

>2211_bases
ATGCCACAACCACCCAAAACATTACTCCCCCTCGGCGCTGCCCTGATGGCCGGCGGGCTGTCAATCAGCGCTTTTGCAGC
AGAAGGAGATGATTACCCCAAAAAAACGCCTGTTCTCCCTACCATCAAGGTAGAAGCAGGTGCCGAAGCTGAAAAAGACG
GGTACCGTGCCACCACCACCCGTGTCGGCAAAACGTTGCAGGATCCGCACGACATCCCTCAGGCGGTGACGACCGTCACC
AACCAGTTGATGGAAGACCAACAAGTCAGCTCGCTCAAGGATGCGCTGCGCAATGTTGCCGGCCTGACTTTCAACGCTGC
CGAGGGTGGACGTTCTGGCGACAATATGATGTTGCGTGGCTTCTATACCTTTGGTGATATTTATCTGGATGGCATTCGCG
ATACGGCGCAGTACAATCGTGAAACTTTCTATCTGGAACAAATCGATGTACTGCGTGGTGCCGGAGCAATGATGTTTGGG
CGTGGTCAGGCCGGTGGTGTTATCAACCAGGTCAGCAAAGTGCCGCATCTGGGAGACAGGGGGAAAATTACCGGTAGTGT
GGGCATGTACGGTTACTACGAGATGACCGGTGATTTCAACAAACAGATTACTGACACCATCGCCTTCCGCTTCAATGGAA
TGAAACGGTTTGATGGCGGCTGGCGTAAAAACCCGGCAGCCAATGACAGACCGACACTGGAACGGGACGGGGTCGCCGCC
AGCTTGGGGATCGGGCTTAACACCGACAACGAACTTATTCTGAGCCATATCTACACCACAGTAGATGACAAGCCGGATTA
CGGTGTGAACTTCGACAGCACAACACGCAAACCACAAGAAAAATTTCCAGTGAAATATTACTGGGGTACCAACAGTAATT
TTGACAAAGGTACAGTTAATATCTCAACCGCCACCTTTACCCATCATTTCTCGCCTGCCAGTGAATGGCGCACGCAGGTA
CGTTATGCGGACTATGAACGCAGTTACTGGGCACGTACCCCCAGCCTGACTATTGCCCCCAATGCCGAAGGCAAGGTATG
TAACACACCCACATCGTGTAATGGCGGCCCAACCCGCACCATGAATTACAAAACCATAACGGTACAGACAGACTATAACC
ATCGATTCCATTTGTTTGGTATGAATCACGATTTCCTGCTGGGCGGGGAATATCTCAATGAAGACAGCTTCCGTCATTCT
CTACAAAACTTCAGTGGAACCACGTCAGCCAATCCGCCTCTGTTCCGGCCTTACAAAGCCAACTCAGCAGGAATTCCAGT
CGAATTTAATTCCGATACTTACGCAGTATATGTACAGGATACGGTTGAATTTATCCCCAAATGGAAACTCACACTGGGAG
GAAGACGCGATGAAATGCGGGCAACATATTCCAGCGCGACCTCTCCCAAGCTGAATTATGGTCAATGGAGTACACGCGCA
GCACTGTCCTACCACTTTTCCGATCAATCCCATCTTTATATGGCGTCCAGCAGCTCATTCAGCCCGACAGCCGATTTGTA
TCAACTCACCGTTCAACCTCTGCCACCGGAACGCAGTAATGTCAAAGAAATTGGCGCCAAATGGCTACTGTTTGATGGTG
ACCTCGCATTGCGTACAGCACTCTATCATGCAGAAAAAAAATGGGAGCGTAATACCGATCTGGAATCCACTGCGGCAATT
CTTACCAAAAAGCGCCGTACAAACGGCATTGAACTGGAACTGGCAGGCCGTATTACACCCAACTGGGAAGTATTCTCCGG
GCTTGCTCTGATGGATCCGGAGATTCTGGAAGTTGCTGAAAACGTCAACGCCACAACAGGTGTTCTGACTTCAGCCAACC
CGGAATATAAAGGCAAACGTCCGCGCAACACCCCGCCCTACACATTTAACCTGTGGACCACTTACAGGCTGCCTTATGGC
TGGAAAATAGGCGGCGGTGTCGAGGTCAAAGGCAAGCGTTACGGTTACAATCCAAGTGGCGCCGGCCCAATCCCTACCTT
GCCAGGTGAAACCAAGTTCCATCCGAACACTGCACCTGCCTACATGCGCTGGGATGCGATGGTGGCCTATGAACAACCGA
AATGGGCTATGCGGCTGAATGTACAGAACGTGTTCAACACAACCTATTATGATGCCATCTATGACAACGGCCCATTTACT
ATCCCTGGCCAGCGTCGCAGAGTTATCATGACAGCCGAATACAAATTCTGA

Upstream 100 bases:

>100_bases
TCGAATTGTTCACGACTGATGTCGCTCGGGTAACTTCTTCTCATCTTCCGAGTTTCTCATACTCCCCTAGACTTTGAACA
GGTTCTTAGAAGGAAATTAA

Downstream 100 bases:

>100_bases
TTTAGTCCTAACCGAAAATATAATCAAGTGCTGCTGACGATCGACAATGTATTAACTGAAGAGGAGCTCGCAGCAGCAAG
CAGTCTGTTAGCTGAATCTG

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: Virulence-associated outer membrane protein Vir-90 [H]

Number of amino acids: Translated: 736; Mature: 735

Protein sequence:

>736_residues
MPQPPKTLLPLGAALMAGGLSISAFAAEGDDYPKKTPVLPTIKVEAGAEAEKDGYRATTTRVGKTLQDPHDIPQAVTTVT
NQLMEDQQVSSLKDALRNVAGLTFNAAEGGRSGDNMMLRGFYTFGDIYLDGIRDTAQYNRETFYLEQIDVLRGAGAMMFG
RGQAGGVINQVSKVPHLGDRGKITGSVGMYGYYEMTGDFNKQITDTIAFRFNGMKRFDGGWRKNPAANDRPTLERDGVAA
SLGIGLNTDNELILSHIYTTVDDKPDYGVNFDSTTRKPQEKFPVKYYWGTNSNFDKGTVNISTATFTHHFSPASEWRTQV
RYADYERSYWARTPSLTIAPNAEGKVCNTPTSCNGGPTRTMNYKTITVQTDYNHRFHLFGMNHDFLLGGEYLNEDSFRHS
LQNFSGTTSANPPLFRPYKANSAGIPVEFNSDTYAVYVQDTVEFIPKWKLTLGGRRDEMRATYSSATSPKLNYGQWSTRA
ALSYHFSDQSHLYMASSSSFSPTADLYQLTVQPLPPERSNVKEIGAKWLLFDGDLALRTALYHAEKKWERNTDLESTAAI
LTKKRRTNGIELELAGRITPNWEVFSGLALMDPEILEVAENVNATTGVLTSANPEYKGKRPRNTPPYTFNLWTTYRLPYG
WKIGGGVEVKGKRYGYNPSGAGPIPTLPGETKFHPNTAPAYMRWDAMVAYEQPKWAMRLNVQNVFNTTYYDAIYDNGPFT
IPGQRRRVIMTAEYKF

Sequences:

>Translated_736_residues
MPQPPKTLLPLGAALMAGGLSISAFAAEGDDYPKKTPVLPTIKVEAGAEAEKDGYRATTTRVGKTLQDPHDIPQAVTTVT
NQLMEDQQVSSLKDALRNVAGLTFNAAEGGRSGDNMMLRGFYTFGDIYLDGIRDTAQYNRETFYLEQIDVLRGAGAMMFG
RGQAGGVINQVSKVPHLGDRGKITGSVGMYGYYEMTGDFNKQITDTIAFRFNGMKRFDGGWRKNPAANDRPTLERDGVAA
SLGIGLNTDNELILSHIYTTVDDKPDYGVNFDSTTRKPQEKFPVKYYWGTNSNFDKGTVNISTATFTHHFSPASEWRTQV
RYADYERSYWARTPSLTIAPNAEGKVCNTPTSCNGGPTRTMNYKTITVQTDYNHRFHLFGMNHDFLLGGEYLNEDSFRHS
LQNFSGTTSANPPLFRPYKANSAGIPVEFNSDTYAVYVQDTVEFIPKWKLTLGGRRDEMRATYSSATSPKLNYGQWSTRA
ALSYHFSDQSHLYMASSSSFSPTADLYQLTVQPLPPERSNVKEIGAKWLLFDGDLALRTALYHAEKKWERNTDLESTAAI
LTKKRRTNGIELELAGRITPNWEVFSGLALMDPEILEVAENVNATTGVLTSANPEYKGKRPRNTPPYTFNLWTTYRLPYG
WKIGGGVEVKGKRYGYNPSGAGPIPTLPGETKFHPNTAPAYMRWDAMVAYEQPKWAMRLNVQNVFNTTYYDAIYDNGPFT
IPGQRRRVIMTAEYKF
>Mature_735_residues
PQPPKTLLPLGAALMAGGLSISAFAAEGDDYPKKTPVLPTIKVEAGAEAEKDGYRATTTRVGKTLQDPHDIPQAVTTVTN
QLMEDQQVSSLKDALRNVAGLTFNAAEGGRSGDNMMLRGFYTFGDIYLDGIRDTAQYNRETFYLEQIDVLRGAGAMMFGR
GQAGGVINQVSKVPHLGDRGKITGSVGMYGYYEMTGDFNKQITDTIAFRFNGMKRFDGGWRKNPAANDRPTLERDGVAAS
LGIGLNTDNELILSHIYTTVDDKPDYGVNFDSTTRKPQEKFPVKYYWGTNSNFDKGTVNISTATFTHHFSPASEWRTQVR
YADYERSYWARTPSLTIAPNAEGKVCNTPTSCNGGPTRTMNYKTITVQTDYNHRFHLFGMNHDFLLGGEYLNEDSFRHSL
QNFSGTTSANPPLFRPYKANSAGIPVEFNSDTYAVYVQDTVEFIPKWKLTLGGRRDEMRATYSSATSPKLNYGQWSTRAA
LSYHFSDQSHLYMASSSSFSPTADLYQLTVQPLPPERSNVKEIGAKWLLFDGDLALRTALYHAEKKWERNTDLESTAAIL
TKKRRTNGIELELAGRITPNWEVFSGLALMDPEILEVAENVNATTGVLTSANPEYKGKRPRNTPPYTFNLWTTYRLPYGW
KIGGGVEVKGKRYGYNPSGAGPIPTLPGETKFHPNTAPAYMRWDAMVAYEQPKWAMRLNVQNVFNTTYYDAIYDNGPFTI
PGQRRRVIMTAEYKF

Specific function: Probably involved in iron transport [H]

COG id: COG4774

COG function: function code P; Outer membrane receptor for monomeric catechols

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787024, Length=734, Percent_Identity=26.566757493188, Blast_Score=196, Evalue=5e-51,
Organism=Escherichia coli, GI1786344, Length=793, Percent_Identity=20.8070617906683, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1787344, Length=786, Percent_Identity=23.4096692111959, Blast_Score=102, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 82228; Mature: 82097

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQPPKTLLPLGAALMAGGLSISAFAAEGDDYPKKTPVLPTIKVEAGAEAEKDGYRATTT
CCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCEEHHH
RVGKTLQDPHDIPQAVTTVTNQLMEDQQVSSLKDALRNVAGLTFNAAEGGRSGDNMMLRG
HHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCEEEEE
FYTFGDIYLDGIRDTAQYNRETFYLEQIDVLRGAGAMMFGRGQAGGVINQVSKVPHLGDR
EEEECEEEEECCHHHHHCCCCEEEEEHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCCC
GKITGSVGMYGYYEMTGDFNKQITDTIAFRFNGMKRFDGGWRKNPAANDRPTLERDGVAA
CEEEECCCCEEEEEECCCCCHHHHHEEEEEECCCHHCCCCCCCCCCCCCCCCCCCCCCEE
SLGIGLNTDNELILSHIYTTVDDKPDYGVNFDSTTRKPQEKFPVKYYWGTNSNFDKGTVN
EEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCEEEEECCCCCCCCCEEE
ISTATFTHHFSPASEWRTQVRYADYERSYWARTPSLTIAPNAEGKVCNTPTSCNGGPTRT
EEEEEEEECCCCHHHHHHHHEECCCCCHHHCCCCCEEECCCCCCCEECCCCCCCCCCCEE
MNYKTITVQTDYNHRFHLFGMNHDFLLGGEYLNEDSFRHSLQNFSGTTSANPPLFRPYKA
EEEEEEEEEECCCCEEEEEECCCCEEECCHHCCCHHHHHHHHHCCCCCCCCCCEECCCCC
NSAGIPVEFNSDTYAVYVQDTVEFIPKWKLTLGGRRDEMRATYSSATSPKLNYGQWSTRA
CCCCCCEEECCCEEEEEEECHHHHCCCEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCEE
ALSYHFSDQSHLYMASSSSFSPTADLYQLTVQPLPPERSNVKEIGAKWLLFDGDLALRTA
EEEEEECCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCHHHHCCEEEEEECCHHHHHH
LYHAEKKWERNTDLESTAAILTKKRRTNGIELELAGRITPNWEVFSGLALMDPEILEVAE
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHCCEECCCHHHHHHHH
NVNATTGVLTSANPEYKGKRPRNTPPYTFNLWTTYRLPYGWKIGGGVEVKGKRYGYNPSG
CCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEECCCEEECCCCCCCCCCC
AGPIPTLPGETKFHPNTAPAYMRWDAMVAYEQPKWAMRLNVQNVFNTTYYDAIYDNGPFT
CCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEEHHHHHCCEEEEEEECCCCEE
IPGQRRRVIMTAEYKF
CCCCCEEEEEEEECCC
>Mature Secondary Structure 
PQPPKTLLPLGAALMAGGLSISAFAAEGDDYPKKTPVLPTIKVEAGAEAEKDGYRATTT
CCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCEEHHH
RVGKTLQDPHDIPQAVTTVTNQLMEDQQVSSLKDALRNVAGLTFNAAEGGRSGDNMMLRG
HHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCEEEEE
FYTFGDIYLDGIRDTAQYNRETFYLEQIDVLRGAGAMMFGRGQAGGVINQVSKVPHLGDR
EEEECEEEEECCHHHHHCCCCEEEEEHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCCC
GKITGSVGMYGYYEMTGDFNKQITDTIAFRFNGMKRFDGGWRKNPAANDRPTLERDGVAA
CEEEECCCCEEEEEECCCCCHHHHHEEEEEECCCHHCCCCCCCCCCCCCCCCCCCCCCEE
SLGIGLNTDNELILSHIYTTVDDKPDYGVNFDSTTRKPQEKFPVKYYWGTNSNFDKGTVN
EEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCEEEEECCCCCCCCCEEE
ISTATFTHHFSPASEWRTQVRYADYERSYWARTPSLTIAPNAEGKVCNTPTSCNGGPTRT
EEEEEEEECCCCHHHHHHHHEECCCCCHHHCCCCCEEECCCCCCCEECCCCCCCCCCCEE
MNYKTITVQTDYNHRFHLFGMNHDFLLGGEYLNEDSFRHSLQNFSGTTSANPPLFRPYKA
EEEEEEEEEECCCCEEEEEECCCCEEECCHHCCCHHHHHHHHHCCCCCCCCCCEECCCCC
NSAGIPVEFNSDTYAVYVQDTVEFIPKWKLTLGGRRDEMRATYSSATSPKLNYGQWSTRA
CCCCCCEEECCCEEEEEEECHHHHCCCEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCEE
ALSYHFSDQSHLYMASSSSFSPTADLYQLTVQPLPPERSNVKEIGAKWLLFDGDLALRTA
EEEEEECCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCHHHHCCEEEEEECCHHHHHH
LYHAEKKWERNTDLESTAAILTKKRRTNGIELELAGRITPNWEVFSGLALMDPEILEVAE
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHCCEECCCHHHHHHHH
NVNATTGVLTSANPEYKGKRPRNTPPYTFNLWTTYRLPYGWKIGGGVEVKGKRYGYNPSG
CCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEECCCEEECCCCCCCCCCC
AGPIPTLPGETKFHPNTAPAYMRWDAMVAYEQPKWAMRLNVQNVFNTTYYDAIYDNGPFT
CCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEEHHHHHCCEEEEEEECCCCEE
IPGQRRRVIMTAEYKF
CCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12910271; 10079522 [H]