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The map label for this gene is paiA [H]

Identifier: 114330372

GI number: 114330372

Start: 354356

End: 354919

Strand: Direct

Name: paiA [H]

Synonym: Neut_0349

Alternate gene names: 114330372

Gene position: 354356-354919 (Clockwise)

Preceding gene: 114330371

Following gene: 114330373

Centisome position: 13.32

GC content: 51.06

Gene sequence:

>564_bases
ATGAACAGTAAAATCCGGATACGAATCTGTTCATCTGGTGATGAAGCAGCACTTGCACTGATTGGCCAGGCGACATTTCT
CGAAGCGTTTGCGGGCGTTCTGGAGGGACAAAATATTCTCACGCATTGTGCCAACGCCCATTCTGTTGAGTGTTATCGCA
GCTGGCTAGCCGATAGCCGCTATCAACTCTGGCTGGCCGAAATCAGCCCGGGTCACGCCCCCATTGGTTACATGACTGTC
GCGCCATCGCCGTTTTTGCTGCCGGACAGCTCCTCGCGTGATCTTGAATTGAAACGAATTTATATTTTCAGCAAATTTCA
GGGGCGGGGCCTTGGTAAAAGGCTGCTACAGGAAGCCATTGCCGAATCACGTGCCCGCATGGCGGAGCGTTTGTTACTCG
GTGTATATGAACATAATGATGCCGCCATCGGGTTTTATACCCGCATGGGGTTTCGCAAGGTAGGGACGCGCAAATTCAAC
ATGGGCGGGCTGGAATGTGATGACTACGTCATGGGGCTGACAGTCTTTGCTTCCGAGTCTATCCATTCGGAAAATATATT
GTAA

Upstream 100 bases:

>100_bases
GGGCACAGCCTGATCCGGCCGGAATATCAGAAGGCTGGCAGCATTCTCCCCGAATTTTCAGCCGATGAGCGGAATGAGAA
CGATGAAAATGAGTGGCCAG

Downstream 100 bases:

>100_bases
ACTGCCCATTGGTATGACGTGTATTCATCTCTCATAAAAATAGTCGTGTAATCAATCTAAACGGATAACAACAATATGGC
CAGAAATGTGCAATGCATCA

Product: GCN5-related N-acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MNSKIRIRICSSGDEAALALIGQATFLEAFAGVLEGQNILTHCANAHSVECYRSWLADSRYQLWLAEISPGHAPIGYMTV
APSPFLLPDSSSRDLELKRIYIFSKFQGRGLGKRLLQEAIAESRARMAERLLLGVYEHNDAAIGFYTRMGFRKVGTRKFN
MGGLECDDYVMGLTVFASESIHSENIL

Sequences:

>Translated_187_residues
MNSKIRIRICSSGDEAALALIGQATFLEAFAGVLEGQNILTHCANAHSVECYRSWLADSRYQLWLAEISPGHAPIGYMTV
APSPFLLPDSSSRDLELKRIYIFSKFQGRGLGKRLLQEAIAESRARMAERLLLGVYEHNDAAIGFYTRMGFRKVGTRKFN
MGGLECDDYVMGLTVFASESIHSENIL
>Mature_187_residues
MNSKIRIRICSSGDEAALALIGQATFLEAFAGVLEGQNILTHCANAHSVECYRSWLADSRYQLWLAEISPGHAPIGYMTV
APSPFLLPDSSSRDLELKRIYIFSKFQGRGLGKRLLQEAIAESRARMAERLLLGVYEHNDAAIGFYTRMGFRKVGTRKFN
MGGLECDDYVMGLTVFASESIHSENIL

Specific function: Possesses N1-acetyltransferase activity toward polyamine substrates including spermidine and spermine. Can acetylate both spermidine and spermine. In this way it may function in regulating intracellular polyamine concentrations and/or binding capabilities

COG id: COG0454

COG function: function code KR; Histone acetyltransferase HPA2 and related acetyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: NA

Molecular weight: Translated: 20798; Mature: 20798

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKIRIRICSSGDEAALALIGQATFLEAFAGVLEGQNILTHCANAHSVECYRSWLADSR
CCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHCCCC
YQLWLAEISPGHAPIGYMTVAPSPFLLPDSSSRDLELKRIYIFSKFQGRGLGKRLLQEAI
EEEEEEECCCCCCCEEEEEECCCCEECCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHH
AESRARMAERLLLGVYEHNDAAIGFYTRMGFRKVGTRKFNMGGLECDDYVMGLTVFASES
HHHHHHHHHHHHHHEEECCCCEEEHHHHHCHHHCCCEEECCCCCCCCHHHHHHHEEECCC
IHSENIL
CCCCCCC
>Mature Secondary Structure
MNSKIRIRICSSGDEAALALIGQATFLEAFAGVLEGQNILTHCANAHSVECYRSWLADSR
CCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHCCCC
YQLWLAEISPGHAPIGYMTVAPSPFLLPDSSSRDLELKRIYIFSKFQGRGLGKRLLQEAI
EEEEEEECCCCCCCEEEEEECCCCEECCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHH
AESRARMAERLLLGVYEHNDAAIGFYTRMGFRKVGTRKFNMGGLECDDYVMGLTVFASES
HHHHHHHHHHHHHHEEECCCCEEEHHHHHCHHHCCCEEECCCCCCCCHHHHHHHEEECCC
IHSENIL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2108124; 9384377 [H]