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The map label for this gene is queC

Identifier: 114330320

GI number: 114330320

Start: 301644

End: 302324

Strand: Direct

Name: queC

Synonym: Neut_0293

Alternate gene names: 114330320

Gene position: 301644-302324 (Clockwise)

Preceding gene: 114330319

Following gene: 114330322

Centisome position: 11.34

GC content: 49.34

Gene sequence:

>681_bases
ATGAAAAAAGCAGTTGTGCTGTTATCAGGAGGGCTGGATTCCACTACAACACTTGCTATTGCCAGGGGAAATGGGTTTGC
CTGTTACGCACTCAGTGTTGATTATGGTCAGCGTCATGCTGCCGAGCTAGCTGCTGCAACGCGAATTGGTCAATTACTCC
AGGTTTGTGAACATCAGTTTCTCAAGCTGGATTTGACTGTTCTGGCCAGCTCTGCGCTGACCGATCCTTCTGTTACTGTT
CCGATACATGGCACCAATCGAGGAATTCCAGCCACTTATGTTCCGGCCCGAAACACCATTATGTTGTCGCTGGCGCTGGC
ATGGGCGGAGGTGCTGGGCAGCCAGGATATTTTCATCGGTGTAACAGCTGTTGATTATTCTGGATATCCTGATTGCCGGC
CGGATTATATTGATGCTTTTGAGAAAATGGCGAATCTGGCCACAAAAGCAGGAAGAGAAGGCAATCTTCTAAAGGTGCAT
GCTCCTTTAATTAATCTGCCCAAACATGACATCATTCGTCGCGGCCTGGAGCTTGGAATAGATTACAGTATGACTGTTTC
CTGTTACCAGGCAGATGCAAGCGGGTGGGCTTGCGGTCAGTGTGATGCGTGCCATATCCGCCGAGCTGGTTTTGCAGCGG
CAAATATTCCCGACCCAACATACTACCAGGACAAACGATGA

Upstream 100 bases:

>100_bases
GATATTACAAGATAGATTGCCGGTTCGTTTGCAATTCCAGCTACATAAGTTGCTCTGGGGGGAGTGTGTCGGGCGATAAA
ACAGTAGACGGGTTTGATTC

Downstream 100 bases:

>100_bases
TTACAATCGACTGCGCTCGATGCAGATACCAAGCTGTTTCACCCCTTGAATAACATCCAGTTTTGCTGCACTGACTTTTA
CCCAGGGTGAGCCAAATTCG

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKKAVVLLSGGLDSTTTLAIARGNGFACYALSVDYGQRHAAELAAATRIGQLLQVCEHQFLKLDLTVLASSALTDPSVTV
PIHGTNRGIPATYVPARNTIMLSLALAWAEVLGSQDIFIGVTAVDYSGYPDCRPDYIDAFEKMANLATKAGREGNLLKVH
APLINLPKHDIIRRGLELGIDYSMTVSCYQADASGWACGQCDACHIRRAGFAAANIPDPTYYQDKR

Sequences:

>Translated_226_residues
MKKAVVLLSGGLDSTTTLAIARGNGFACYALSVDYGQRHAAELAAATRIGQLLQVCEHQFLKLDLTVLASSALTDPSVTV
PIHGTNRGIPATYVPARNTIMLSLALAWAEVLGSQDIFIGVTAVDYSGYPDCRPDYIDAFEKMANLATKAGREGNLLKVH
APLINLPKHDIIRRGLELGIDYSMTVSCYQADASGWACGQCDACHIRRAGFAAANIPDPTYYQDKR
>Mature_226_residues
MKKAVVLLSGGLDSTTTLAIARGNGFACYALSVDYGQRHAAELAAATRIGQLLQVCEHQFLKLDLTVLASSALTDPSVTV
PIHGTNRGIPATYVPARNTIMLSLALAWAEVLGSQDIFIGVTAVDYSGYPDCRPDYIDAFEKMANLATKAGREGNLLKVH
APLINLPKHDIIRRGLELGIDYSMTVSCYQADASGWACGQCDACHIRRAGFAAANIPDPTYYQDKR

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=225, Percent_Identity=35.5555555555556, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_NITEC (Q0AJ94)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746542.1
- ProteinModelPortal:   Q0AJ94
- SMR:   Q0AJ94
- STRING:   Q0AJ94
- GeneID:   4272066
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0293
- NMPDR:   fig|335283.3.peg.2248
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- PhylomeDB:   Q0AJ94
- ProtClustDB:   CLSK585226
- BioCyc:   NEUT335283:NEUT_0293-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 24303; Mature: 24303

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAVVLLSGGLDSTTTLAIARGNGFACYALSVDYGQRHAAELAAATRIGQLLQVCEHQF
CCCEEEEEECCCCCCEEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LKLDLTVLASSALTDPSVTVPIHGTNRGIPATYVPARNTIMLSLALAWAEVLGSQDIFIG
HEEHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCCEEEHHHHHHHHHHHCCCCEEEE
VTAVDYSGYPDCRPDYIDAFEKMANLATKAGREGNLLKVHAPLINLPKHDIIRRGLELGI
EEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCEECCCHHHHHHHHHHHCC
DYSMTVSCYQADASGWACGQCDACHIRRAGFAAANIPDPTYYQDKR
CEEEEEEEEEECCCCCCCCCCCHHHHHHCCCEECCCCCCCCCCCCC
>Mature Secondary Structure
MKKAVVLLSGGLDSTTTLAIARGNGFACYALSVDYGQRHAAELAAATRIGQLLQVCEHQF
CCCEEEEEECCCCCCEEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LKLDLTVLASSALTDPSVTVPIHGTNRGIPATYVPARNTIMLSLALAWAEVLGSQDIFIG
HEEHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCCEEEHHHHHHHHHHHCCCCEEEE
VTAVDYSGYPDCRPDYIDAFEKMANLATKAGREGNLLKVHAPLINLPKHDIIRRGLELGI
EEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCEECCCHHHHHHHHHHHCC
DYSMTVSCYQADASGWACGQCDACHIRRAGFAAANIPDPTYYQDKR
CEEEEEEEEEECCCCCCCCCCCHHHHHHCCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA