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The map label for this gene is rmlA1 [C]

Identifier: 114330295

GI number: 114330295

Start: 279608

End: 280414

Strand: Reverse

Name: rmlA1 [C]

Synonym: Neut_0268

Alternate gene names: 114330295

Gene position: 280414-279608 (Counterclockwise)

Preceding gene: 114330296

Following gene: 114330294

Centisome position: 10.54

GC content: 44.98

Gene sequence:

>807_bases
ATGACTGACCAAATTGATGATTTTCCGGGTAAGGCGATCATTCTGAGTGCCGGGCAGGGTAGACGATTATTACCCTTGAC
CGAAGATACTCCTAAATGCCTGTTGCCAGTTTCAGGAAAACCGGTGATTGCTTGGCAGATTGATACCTTACTGGCCAATG
GTATCCAGGAAATCGTAATCGTCGCCGGCTTCCAAATTGGCAAAGTGGAAATGCTGTTAGCCGAACGCTATCCGAATCAT
TCTAATATTCGGGTTGTATTTAATCCTTTCTACGAAGTAGCGGATAATCTGGCCAGTTGCTGGATTGCACGTGAAGAGAT
GAATACCGGATTTCTATTACTGAATGGTGATACGCTGCTGGAAGATAATTTGCTGTCAGGTGTGTTGCGCACACAAATAG
CACCAATTACTTTATGCATTGATTTTAAAGAAAAATTTGATGACGATGACATGAAGGTTCAGCTTGATCTGCTAGGCCAA
GTGAAACAGGTCAGCAAGAAACTGTCTGTAGAGGAAACCAATGCAGAATCAATTGGACTGATTCGTTTCAGCGGGCAAGG
TGCGCGGCTTTTCCGTAATGCAGTGGAGCAGGCATTACGCGAACCGGAGAAACTTGGATCGTGGTATCTGGCTATTATCA
GTGCGTTAGCTAAACAAGGTATAGTAAGCAGCCACTCGGTTGTTGGTAATCACTGGTGTGAAATTGACTTTATTCAGGAT
TTACAGAGGGCGAGAAACTACTTCCCTTGTGTGGAGATTGCTGCAGATCAATCGCAATCTGATCAGTTCCTGCAGGCACC
AGGCTGA

Upstream 100 bases:

>100_bases
GCTATCAGGCATATAGCGGATGAATTGAGAAAAATGAGCGTACTGCTAAATGTGTGAATATATCGAAAGAACCCGTAATT
GAATAGAGCCGGATATAAAA

Downstream 100 bases:

>100_bases
TCTGGAGAAAAGATAGTGAGTATGAAAATATTTAATGGCACCATGCAGAAGTTTGGCGCGCCAGACACAGTTATTTGCCA
GTTTCAGTATTGGAGCGTGC

Product: nucleotidyl transferase

Products: dTDPglucose; Diphosphate [C]

Alternate protein names: Nucleotide Sugar-1-Phosphate Transferase; Nucleotidyltransferase Family Protein; Hemolysin Erythrocyte Lysis; Sugar Nucleotidyltransferase; Glucose-1-Phosphate Cytidylyltransferase; Aminotransferase Class I And II; Sugar Nucleotidyltransferase-Like Protein; LicC Protein; Phosphoenolpyruvate Phosphomutase; Choline Kinase; Cholinephosphate Cytidylyltransferase/Choline Kinase; Nucleotidyl Transferase Superfamily; Glucose-1-Phosphate Thymidylyltransferase; Sugar-Phosphate Nucleotidyl Transferase; Glucose-1-Phosphate Thymidylyltransferase-Like Protein; LicC-Like Protein; Aminotransferase; ADP-Glucose Pyrophosphorylase; Mannose-1-Phosphate Guanyltransferase Protein; CTPPhosphocholine Cytidylyltransferase; Nucleotidyl Transferase WchZ; 2 3-Dimethylmalate Lyase; UDP-N-Acetylglucosamine Pyrophosphorylase Related Protein; Glucose-1-P-Cytidylyltransferase; Cholinephosphate Cytidylyltransferase; Mannose-1-Phosphate Guanylyltransferase; Phosphoenolpyruvate Mutase

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTDQIDDFPGKAIILSAGQGRRLLPLTEDTPKCLLPVSGKPVIAWQIDTLLANGIQEIVIVAGFQIGKVEMLLAERYPNH
SNIRVVFNPFYEVADNLASCWIAREEMNTGFLLLNGDTLLEDNLLSGVLRTQIAPITLCIDFKEKFDDDDMKVQLDLLGQ
VKQVSKKLSVEETNAESIGLIRFSGQGARLFRNAVEQALREPEKLGSWYLAIISALAKQGIVSSHSVVGNHWCEIDFIQD
LQRARNYFPCVEIAADQSQSDQFLQAPG

Sequences:

>Translated_268_residues
MTDQIDDFPGKAIILSAGQGRRLLPLTEDTPKCLLPVSGKPVIAWQIDTLLANGIQEIVIVAGFQIGKVEMLLAERYPNH
SNIRVVFNPFYEVADNLASCWIAREEMNTGFLLLNGDTLLEDNLLSGVLRTQIAPITLCIDFKEKFDDDDMKVQLDLLGQ
VKQVSKKLSVEETNAESIGLIRFSGQGARLFRNAVEQALREPEKLGSWYLAIISALAKQGIVSSHSVVGNHWCEIDFIQD
LQRARNYFPCVEIAADQSQSDQFLQAPG
>Mature_267_residues
TDQIDDFPGKAIILSAGQGRRLLPLTEDTPKCLLPVSGKPVIAWQIDTLLANGIQEIVIVAGFQIGKVEMLLAERYPNHS
NIRVVFNPFYEVADNLASCWIAREEMNTGFLLLNGDTLLEDNLLSGVLRTQIAPITLCIDFKEKFDDDDMKVQLDLLGQV
KQVSKKLSVEETNAESIGLIRFSGQGARLFRNAVEQALREPEKLGSWYLAIISALAKQGIVSSHSVVGNHWCEIDFIQDL
QRARNYFPCVEIAADQSQSDQFLQAPG

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1213

COG function: function code M; Predicted sugar nucleotidyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.24 [C]

Molecular weight: Translated: 29774; Mature: 29643

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQIDDFPGKAIILSAGQGRRLLPLTEDTPKCLLPVSGKPVIAWQIDTLLANGIQEIVI
CCCCCCCCCCCEEEEECCCCCEEECCCCCCCCEEEECCCCEEEEEEHHHHHHCCHHHHHH
VAGFQIGKVEMLLAERYPNHSNIRVVFNPFYEVADNLASCWIAREEMNTGFLLLNGDTLL
HCCCCCCHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCH
EDNLLSGVLRTQIAPITLCIDFKEKFDDDDMKVQLDLLGQVKQVSKKLSVEETNAESIGL
HHHHHHHHHHHCCCEEEEEEECHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCEEEE
IRFSGQGARLFRNAVEQALREPEKLGSWYLAIISALAKQGIVSSHSVVGNHWCEIDFIQD
EEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHH
LQRARNYFPCVEIAADQSQSDQFLQAPG
HHHHHCCCCEEEEECCCCCCCCEECCCC
>Mature Secondary Structure 
TDQIDDFPGKAIILSAGQGRRLLPLTEDTPKCLLPVSGKPVIAWQIDTLLANGIQEIVI
CCCCCCCCCCEEEEECCCCCEEECCCCCCCCEEEECCCCEEEEEEHHHHHHCCHHHHHH
VAGFQIGKVEMLLAERYPNHSNIRVVFNPFYEVADNLASCWIAREEMNTGFLLLNGDTLL
HCCCCCCHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCH
EDNLLSGVLRTQIAPITLCIDFKEKFDDDDMKVQLDLLGQVKQVSKKLSVEETNAESIGL
HHHHHHHHHHHCCCEEEEEEECHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCEEEE
IRFSGQGARLFRNAVEQALREPEKLGSWYLAIISALAKQGIVSSHSVVGNHWCEIDFIQD
EEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHH
LQRARNYFPCVEIAADQSQSDQFLQAPG
HHHHHCCCCEEEEECCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTTP; D-Glucose 1-phosphate; H+ [C]

Specific reaction: dTTP + D-Glucose 1-phosphate + H+ --> dTDPglucose + Diphosphate [C]

General reaction: Nucleotidyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA