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The map label for this gene is ftsA [H]

Identifier: 114330268

GI number: 114330268

Start: 253599

End: 254837

Strand: Reverse

Name: ftsA [H]

Synonym: Neut_0241

Alternate gene names: 114330268

Gene position: 254837-253599 (Counterclockwise)

Preceding gene: 114330269

Following gene: 114330267

Centisome position: 9.58

GC content: 50.77

Gene sequence:

>1239_bases
ATGAGTAAAGTCAAGGAAGGCAAGAACATGATTGTCGGTCTTGATATCGGCACATCGAAAATCGTGGCTATTGTCGCCGA
AATCAAGCCTGAGGGTGGCTTCGAGATTATTGGTCTGGGTAGCCATCCCTCGCGAGGTCTGAAAAAAGGCGTGGTGGTCA
ATATTGAAGCAACCGTCAACGCCATTCAGCGTGCGCTTGAGGAAGTTGAACTGATGGCGGGTTGCCGGATTAGTGATGTG
TATGCCGGGATCGCCGGCAACCATATCAAGAGTTTTAATTCACATGGCATGGTGGCAATCAAAGACAAAGAAGTCACCCA
GGCGGATGTGGAAAAAGTAATGGAAACTGCCAAGGCGGTCAATATTCCGGCTGATCAGCAAATACTGCACATTCTGCAAC
AGGAATTTATTATCGACGGCCAGGAAGATGTGCGCGAACCAGTCGGAATGAGTGGTATCCGGCTGGAAGTTAAGGTTCAC
ATCGTAACCGGAGCAGTATCCGCCGCCCAGAATATTGCCAAATGCATCAATCGTTGCGGACTGGATGTGCGGGACCTTAT
CCTGCAGCCACTGGCTTCGGCTACAGCTGTACTTTCCGAAGATGAAAAAGATCTGGGGGTATGCCTGGTTGATATCGGCG
GCGGGACTACTGACATTGCTGTTTTTACAGATGGCTCCATACGACATACCGCAGTAATTCCAGTGGCTGGCGATCAGATC
ACCAATGACATTGCCATGGCATTGCGCACACCGACAAAAGATGCAGAGGATATCAAATGCCGTTATGGCACCGCTTTGCG
TACGCTGGCTGATATCCGGGAGATGGTTGAAGTGCCGGATGTGGGCAATCGTGGCGTTCGCCCGCTGTCGCGACAAACCC
TGGCCGAGGTTATCGAGCCGCGCGTAGAAGAGCTCTATCTGCTGATTCAGGCAGAATTGAGACGTAGTGGTTTCGAACAG
CTGCTTTCATCAGGGATTGTCATCACTGGTGGCAGCAGTTCCATGCTGGGCATGGTTGAACTGGGAGAAGAGATTTTTCA
TATGCCCGTGCGACTTGGGTTACCCGCTTATAACGGCAGCCTGGAAGAAGTTGTGCAGACACCGAGATACTCGACTGCCA
TCGGCCTGGTGATGGCAGGCATGGAAGATCATCTTCATCATCACCAGGCAAAACTGAAGAGCGGCTCCACCAGACAGATT
TTGGCAAAAATGAAAAGCTGGTTCCAGGAAAATTTCTAA

Upstream 100 bases:

>100_bases
TTGCGTTATGCCAACGGGTTTGCTGTTCGCATACACTGAGTTTGTGTATTCAATTCAAGGCAAACAGAGCACCATAACTA
TGAAATCGGGGGATTTTCAA

Downstream 100 bases:

>100_bases
ATTAGATTTAAAAAATGTTCTGTCAACGGAATATTGTTTGAAAATTCACTATGCAATAGGAGAAATGTAATGTTTGAGAT
CACGAATACCGAATCCCAGG

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSKVKEGKNMIVGLDIGTSKIVAIVAEIKPEGGFEIIGLGSHPSRGLKKGVVVNIEATVNAIQRALEEVELMAGCRISDV
YAGIAGNHIKSFNSHGMVAIKDKEVTQADVEKVMETAKAVNIPADQQILHILQQEFIIDGQEDVREPVGMSGIRLEVKVH
IVTGAVSAAQNIAKCINRCGLDVRDLILQPLASATAVLSEDEKDLGVCLVDIGGGTTDIAVFTDGSIRHTAVIPVAGDQI
TNDIAMALRTPTKDAEDIKCRYGTALRTLADIREMVEVPDVGNRGVRPLSRQTLAEVIEPRVEELYLLIQAELRRSGFEQ
LLSSGIVITGGSSSMLGMVELGEEIFHMPVRLGLPAYNGSLEEVVQTPRYSTAIGLVMAGMEDHLHHHQAKLKSGSTRQI
LAKMKSWFQENF

Sequences:

>Translated_412_residues
MSKVKEGKNMIVGLDIGTSKIVAIVAEIKPEGGFEIIGLGSHPSRGLKKGVVVNIEATVNAIQRALEEVELMAGCRISDV
YAGIAGNHIKSFNSHGMVAIKDKEVTQADVEKVMETAKAVNIPADQQILHILQQEFIIDGQEDVREPVGMSGIRLEVKVH
IVTGAVSAAQNIAKCINRCGLDVRDLILQPLASATAVLSEDEKDLGVCLVDIGGGTTDIAVFTDGSIRHTAVIPVAGDQI
TNDIAMALRTPTKDAEDIKCRYGTALRTLADIREMVEVPDVGNRGVRPLSRQTLAEVIEPRVEELYLLIQAELRRSGFEQ
LLSSGIVITGGSSSMLGMVELGEEIFHMPVRLGLPAYNGSLEEVVQTPRYSTAIGLVMAGMEDHLHHHQAKLKSGSTRQI
LAKMKSWFQENF
>Mature_411_residues
SKVKEGKNMIVGLDIGTSKIVAIVAEIKPEGGFEIIGLGSHPSRGLKKGVVVNIEATVNAIQRALEEVELMAGCRISDVY
AGIAGNHIKSFNSHGMVAIKDKEVTQADVEKVMETAKAVNIPADQQILHILQQEFIIDGQEDVREPVGMSGIRLEVKVHI
VTGAVSAAQNIAKCINRCGLDVRDLILQPLASATAVLSEDEKDLGVCLVDIGGGTTDIAVFTDGSIRHTAVIPVAGDQIT
NDIAMALRTPTKDAEDIKCRYGTALRTLADIREMVEVPDVGNRGVRPLSRQTLAEVIEPRVEELYLLIQAELRRSGFEQL
LSSGIVITGGSSSMLGMVELGEEIFHMPVRLGLPAYNGSLEEVVQTPRYSTAIGLVMAGMEDHLHHHQAKLKSGSTRQIL
AKMKSWFQENF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=414, Percent_Identity=47.3429951690821, Blast_Score=387, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 44512; Mature: 44381

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVKEGKNMIVGLDIGTSKIVAIVAEIKPEGGFEIIGLGSHPSRGLKKGVVVNIEATVN
CCCCCCCCCEEEEEECCCHHHEEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEHHHHH
AIQRALEEVELMAGCRISDVYAGIAGNHIKSFNSHGMVAIKDKEVTQADVEKVMETAKAV
HHHHHHHHHHHHHCCCHHHHHHCCCCCHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHC
NIPADQQILHILQQEFIIDGQEDVREPVGMSGIRLEVKVHIVTGAVSAAQNIAKCINRCG
CCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEEEEEEEECHHHHHHHHHHHHHHCC
LDVRDLILQPLASATAVLSEDEKDLGVCLVDIGGGTTDIAVFTDGSIRHTAVIPVAGDQI
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEECCCEEEEEEEEECCCHH
TNDIAMALRTPTKDAEDIKCRYGTALRTLADIREMVEVPDVGNRGVRPLSRQTLAEVIEP
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
RVEELYLLIQAELRRSGFEQLLSSGIVITGGSSSMLGMVELGEEIFHMPVRLGLPAYNGS
HHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCHHHCCCCCCCCC
LEEVVQTPRYSTAIGLVMAGMEDHLHHHQAKLKSGSTRQILAKMKSWFQENF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKVKEGKNMIVGLDIGTSKIVAIVAEIKPEGGFEIIGLGSHPSRGLKKGVVVNIEATVN
CCCCCCCCEEEEEECCCHHHEEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEHHHHH
AIQRALEEVELMAGCRISDVYAGIAGNHIKSFNSHGMVAIKDKEVTQADVEKVMETAKAV
HHHHHHHHHHHHHCCCHHHHHHCCCCCHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHC
NIPADQQILHILQQEFIIDGQEDVREPVGMSGIRLEVKVHIVTGAVSAAQNIAKCINRCG
CCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEEEEEEEECHHHHHHHHHHHHHHCC
LDVRDLILQPLASATAVLSEDEKDLGVCLVDIGGGTTDIAVFTDGSIRHTAVIPVAGDQI
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEECCCEEEEEEEEECCCHH
TNDIAMALRTPTKDAEDIKCRYGTALRTLADIREMVEVPDVGNRGVRPLSRQTLAEVIEP
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
RVEELYLLIQAELRRSGFEQLLSSGIVITGGSSSMLGMVELGEEIFHMPVRLGLPAYNGS
HHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCHHHCCCCCCCCC
LEEVVQTPRYSTAIGLVMAGMEDHLHHHQAKLKSGSTRQILAKMKSWFQENF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]