Click here to switch to the map view.

The map label for this gene is coaX

Identifier: 114330260

GI number: 114330260

Start: 246286

End: 247059

Strand: Direct

Name: coaX

Synonym: Neut_0233

Alternate gene names: 114330260

Gene position: 246286-247059 (Clockwise)

Preceding gene: 114330259

Following gene: 114330261

Centisome position: 9.26

GC content: 51.42

Gene sequence:

>774_bases
ATGAACGTATCCTCTTTTCTGCTGGCGATTGATTCCGGTAATACTGCTATCAAATGGGGGTTGCACACGGGTGATCAGTG
GCTGGTGCGTGGCAGTGCACTGCAAAGTGAACGCATGGTGCTGAAACAAGCCTGGGCGCTGCTGCCAGCACCACCTGCAT
CGGTGCTGATTTCCAATGTGGCCGGATTACAAGCTGCAGACGATTTAACAGCGTTGTTAAAACCATGGTATGTCCAGCCG
CACTGGATTACGGCAAGTGCCAGTCAATGTGGTGTAACCAGTCGCTATACCAAACCAGAGCAGTTGGGCTGTGACCGCTG
GGCAGCATTGATTGCCGCTTGGTATAGGGTACAGCGAGCGTGCCTGGTCGTGGATGTGGGTACTGCCATGACAGTCGATA
CACTGTCCTCCACGGGTGAATTTCTAGGGGGCATTATCGTACCCGGGCCGGATGCGATGAAACAAGCACTAGCAGGTTGT
GCCGGAACATTAGCAGCACCTGTTTCCAGCTGTTTCCAGAATTTTCCAGTTAATACTGAAAACGCGTTGTACAGCGGCAT
GATTCAGGCATTAAGTGGTGCGCTGGAGCGAATGTATCGCCTGCTTTCCAGCTATTCGGAAAAACAAACCTTGACGGAAG
TTATCATGACGGGTGGCGGTGCTGCGTTGCTGGCTCAGCATATTCACATTCCTCACCGGATTGTCGATAGCTTGGTGCTG
GAGGGGCTGGCTATTATTGCGAAATCGGGTAACTTCGATTACAACAAAAAATAA

Upstream 100 bases:

>100_bases
CTTACAGATCAATACCCCGACAGGTATCGTGCAATTGAGAAGTGGAGAGGTTTCTCTGCGCGGGCTGATCTGATACGGAT
ATCAGAGATTCCCTAATTGA

Downstream 100 bases:

>100_bases
ACATCAGGACAACGCACTATGGTACACCCGCTTTTCAGGCATGCTGAATTCTACACGACAGTCAACCACATCAAGGATTT
GCCGCAAGCAACTGGTGTTG

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MNVSSFLLAIDSGNTAIKWGLHTGDQWLVRGSALQSERMVLKQAWALLPAPPASVLISNVAGLQAADDLTALLKPWYVQP
HWITASASQCGVTSRYTKPEQLGCDRWAALIAAWYRVQRACLVVDVGTAMTVDTLSSTGEFLGGIIVPGPDAMKQALAGC
AGTLAAPVSSCFQNFPVNTENALYSGMIQALSGALERMYRLLSSYSEKQTLTEVIMTGGGAALLAQHIHIPHRIVDSLVL
EGLAIIAKSGNFDYNKK

Sequences:

>Translated_257_residues
MNVSSFLLAIDSGNTAIKWGLHTGDQWLVRGSALQSERMVLKQAWALLPAPPASVLISNVAGLQAADDLTALLKPWYVQP
HWITASASQCGVTSRYTKPEQLGCDRWAALIAAWYRVQRACLVVDVGTAMTVDTLSSTGEFLGGIIVPGPDAMKQALAGC
AGTLAAPVSSCFQNFPVNTENALYSGMIQALSGALERMYRLLSSYSEKQTLTEVIMTGGGAALLAQHIHIPHRIVDSLVL
EGLAIIAKSGNFDYNKK
>Mature_257_residues
MNVSSFLLAIDSGNTAIKWGLHTGDQWLVRGSALQSERMVLKQAWALLPAPPASVLISNVAGLQAADDLTALLKPWYVQP
HWITASASQCGVTSRYTKPEQLGCDRWAALIAAWYRVQRACLVVDVGTAMTVDTLSSTGEFLGGIIVPGPDAMKQALAGC
AGTLAAPVSSCFQNFPVNTENALYSGMIQALSGALERMYRLLSSYSEKQTLTEVIMTGGGAALLAQHIHIPHRIVDSLVL
EGLAIIAKSGNFDYNKK

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_NITEC (Q0AJF4)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746482.1
- ProteinModelPortal:   Q0AJF4
- STRING:   Q0AJF4
- GeneID:   4272249
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0233
- NMPDR:   fig|335283.3.peg.2106
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   RTTIRSR
- ProtClustDB:   PRK13329
- BioCyc:   NEUT335283:NEUT_0233-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27475; Mature: 27475

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: NA

Important sites: ACT_SITE 105-105 BINDING 96-96 BINDING 128-128 BINDING 179-179

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSSFLLAIDSGNTAIKWGLHTGDQWLVRGSALQSERMVLKQAWALLPAPPASVLISNV
CCCCCEEEEEECCCEEEEECCCCCCHHEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AGLQAADDLTALLKPWYVQPHWITASASQCGVTSRYTKPEQLGCDRWAALIAAWYRVQRA
HCCCHHHHHHHHHHCCCCCCCEEECCCHHCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHH
CLVVDVGTAMTVDTLSSTGEFLGGIIVPGPDAMKQALAGCAGTLAAPVSSCFQNFPVNTE
HEEEECCCCHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
NALYSGMIQALSGALERMYRLLSSYSEKQTLTEVIMTGGGAALLAQHIHIPHRIVDSLVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHH
EGLAIIAKSGNFDYNKK
HHHHHEEECCCCCCCCC
>Mature Secondary Structure
MNVSSFLLAIDSGNTAIKWGLHTGDQWLVRGSALQSERMVLKQAWALLPAPPASVLISNV
CCCCCEEEEEECCCEEEEECCCCCCHHEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AGLQAADDLTALLKPWYVQPHWITASASQCGVTSRYTKPEQLGCDRWAALIAAWYRVQRA
HCCCHHHHHHHHHHCCCCCCCEEECCCHHCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHH
CLVVDVGTAMTVDTLSSTGEFLGGIIVPGPDAMKQALAGCAGTLAAPVSSCFQNFPVNTE
HEEEECCCCHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
NALYSGMIQALSGALERMYRLLSSYSEKQTLTEVIMTGGGAALLAQHIHIPHRIVDSLVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHH
EGLAIIAKSGNFDYNKK
HHHHHEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA