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The map label for this gene is cysQ [H]

Identifier: 114330196

GI number: 114330196

Start: 167783

End: 168601

Strand: Direct

Name: cysQ [H]

Synonym: Neut_0165

Alternate gene names: 114330196

Gene position: 167783-168601 (Clockwise)

Preceding gene: 114330194

Following gene: 114330197

Centisome position: 6.31

GC content: 49.69

Gene sequence:

>819_bases
ATGTGGTTGGTTACGAAATATAATTTCATTATGCAAAAAATTGATCTTACCGCCTTGCTGACAGAATTGTTGCCGATTAT
TCAGGCGGCAGGTGACGCTATCATGGCAGTATACCGGGCCGGGGAGATTGATTTTCAGCAGAAGGCTGATCAAAGTCCGG
TTACCCGAGCTGATCTGGCAGCGCATGATGGGTTGATGCAACGCTTGAAGTTACTGATAGCGGGCTGCCCGGTCGTATCG
GAGGAAGATAAGACATCCCATCAATATCGGGATGATAAAAATCGTTTTTGGTTGATTGATCCGCTTGATGGCACTCGGGA
ATTTATTAACCACAATGGCGAATTTACCGTGAACATCGCTTTGATTGAAGAAGGCCGCAGTGTACTCGGCGCTGTATATG
CGCCTGCTATGGATTGTATGTATTGGGGTGGTCCAGGTTTGGGAGCATTTAGAAGAACGGAATCAGGTACCCAGACGATT
TGCGTGAGTTCGGGAGAGCCTGAAGATATTTGCCGTGTGGTAGCGAGCAGAAGCCATCTCGATGCCGGAACGCAGGCGTT
TATAGATCGCCTGGGAGAAGTGCTGTTGTTACAAGTTGGCAGTTCCTTGAAATTTTGTCGCGTGGCAGAAGGCATGGCAG
ATATTTATCCGCGCCTTGCACCAACCAGCGAATGGGATACCGCAGCTGCTCAGGCTATTCTGGAGGGAGCGGGTGGCAAG
GTGATCGACCTAGATGGGCGAGCATTGCGTTACGGCAAATCAGGCGTACTGAATCCGGCATTCATTGCCGTGCGCGATGT
TGCATTGATTCCTGTTTGA

Upstream 100 bases:

>100_bases
TCTACGCAAATGAGAACGTGCAGTCTGTCAGATTGAGTGGATGTTATTAGCGGTTTGGTTGTTAAAGTCTCTTCCTGATG
CATTATTTGTTAGCAGGCTG

Downstream 100 bases:

>100_bases
TTGGCTGTGGACAGTTCAGGGATGGCTGGGGACGAATTGAGTGGTTTGCTTGATCAACAAGTAGCCGTTCTGATGTGCAC
ATACAATGGTGCACATTACT

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MWLVTKYNFIMQKIDLTALLTELLPIIQAAGDAIMAVYRAGEIDFQQKADQSPVTRADLAAHDGLMQRLKLLIAGCPVVS
EEDKTSHQYRDDKNRFWLIDPLDGTREFINHNGEFTVNIALIEEGRSVLGAVYAPAMDCMYWGGPGLGAFRRTESGTQTI
CVSSGEPEDICRVVASRSHLDAGTQAFIDRLGEVLLLQVGSSLKFCRVAEGMADIYPRLAPTSEWDTAAAQAILEGAGGK
VIDLDGRALRYGKSGVLNPAFIAVRDVALIPV

Sequences:

>Translated_272_residues
MWLVTKYNFIMQKIDLTALLTELLPIIQAAGDAIMAVYRAGEIDFQQKADQSPVTRADLAAHDGLMQRLKLLIAGCPVVS
EEDKTSHQYRDDKNRFWLIDPLDGTREFINHNGEFTVNIALIEEGRSVLGAVYAPAMDCMYWGGPGLGAFRRTESGTQTI
CVSSGEPEDICRVVASRSHLDAGTQAFIDRLGEVLLLQVGSSLKFCRVAEGMADIYPRLAPTSEWDTAAAQAILEGAGGK
VIDLDGRALRYGKSGVLNPAFIAVRDVALIPV
>Mature_272_residues
MWLVTKYNFIMQKIDLTALLTELLPIIQAAGDAIMAVYRAGEIDFQQKADQSPVTRADLAAHDGLMQRLKLLIAGCPVVS
EEDKTSHQYRDDKNRFWLIDPLDGTREFINHNGEFTVNIALIEEGRSVLGAVYAPAMDCMYWGGPGLGAFRRTESGTQTI
CVSSGEPEDICRVVASRSHLDAGTQAFIDRLGEVLLLQVGSSLKFCRVAEGMADIYPRLAPTSEWDTAAAQAILEGAGGK
VIDLDGRALRYGKSGVLNPAFIAVRDVALIPV

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI116812595, Length=277, Percent_Identity=26.3537906137184, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1790659, Length=245, Percent_Identity=46.9387755102041, Blast_Score=196, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI71995897, Length=280, Percent_Identity=25.7142857142857, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71995905, Length=283, Percent_Identity=25.7950530035336, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29643; Mature: 29643

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLVTKYNFIMQKIDLTALLTELLPIIQAAGDAIMAVYRAGEIDFQQKADQSPVTRADLA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHCCCCCCCHHHHH
AHDGLMQRLKLLIAGCPVVSEEDKTSHQYRDDKNRFWLIDPLDGTREFINHNGEFTVNIA
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEEEECCCHHHHHHCCCCCEEEEEE
LIEEGRSVLGAVYAPAMDCMYWGGPGLGAFRRTESGTQTICVSSGEPEDICRVVASRSHL
EEECCHHHHHHHHHHHHHHHEECCCCCCCHHCCCCCCEEEEECCCCHHHHHHHHHHHCCC
DAGTQAFIDRLGEVLLLQVGSSLKFCRVAEGMADIYPRLAPTSEWDTAAAQAILEGAGGK
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCC
VIDLDGRALRYGKSGVLNPAFIAVRDVALIPV
EEECCCCEEECCCCCCCCHHHHHHHHEEECCC
>Mature Secondary Structure
MWLVTKYNFIMQKIDLTALLTELLPIIQAAGDAIMAVYRAGEIDFQQKADQSPVTRADLA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHCCCCCCCHHHHH
AHDGLMQRLKLLIAGCPVVSEEDKTSHQYRDDKNRFWLIDPLDGTREFINHNGEFTVNIA
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEEEECCCHHHHHHCCCCCEEEEEE
LIEEGRSVLGAVYAPAMDCMYWGGPGLGAFRRTESGTQTICVSSGEPEDICRVVASRSHL
EEECCHHHHHHHHHHHHHHHEECCCCCCCHHCCCCCCEEEEECCCCHHHHHHHHHHHCCC
DAGTQAFIDRLGEVLLLQVGSSLKFCRVAEGMADIYPRLAPTSEWDTAAAQAILEGAGGK
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCC
VIDLDGRALRYGKSGVLNPAFIAVRDVALIPV
EEECCCCEEECCCCCCCCHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]