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The map label for this gene is hmrR2 [H]

Identifier: 114330099

GI number: 114330099

Start: 68919

End: 69281

Strand: Direct

Name: hmrR2 [H]

Synonym: Neut_0068

Alternate gene names: 114330099

Gene position: 68919-69281 (Clockwise)

Preceding gene: 114330098

Following gene: 114330101

Centisome position: 2.59

GC content: 53.72

Gene sequence:

>363_bases
ATGATCCGATATTATGAACAAACTGGACTGATCCCCCCGGCCAATCGCAGGGAGTCGGGTTATCGCAATTACTCTGCGTC
TGATGTGCACATGCTGCGGTTTATCCGCCGAGGGCGTGATCTTGGCTTCCCGGTGGCACAGATCAATGAACTTTTAGGCC
TCTGGCGTGACAAATCGCGCCAGAGCGCCGAGGTAAAACGTATCGCTACGGCTCACATAACAGAGCTGCGCGAGAAGATC
GACAGCCTGGAACAAATTGCCAGTACGCTTCAGACCCTGATCGAGTGTTGCTCCGGCGATGACCGTCCCGATTGTCCGAT
TTTGGATGACCTCGAGAACACAGCCGATAGACAGCAATTGTAG

Upstream 100 bases:

>100_bases
GCTACCAAATCCTCTCAACTGCCGACGACGGCGTAGTTGGAAAGGAGATATTGAAATGAATATTGGGGAAGTAGCGAAAG
CCTCAGGTGTCTCAGCGAAG

Downstream 100 bases:

>100_bases
CTAGCCCGCTGCGATTGCTGGCTAGTTCGTTGCGGCCCAAATTAAATCATTCGAGATTGAGATAGGGATTATTCGTCGGT
AACTCGTCAAACAAGTGCTT

Product: transcriptional regulator, MerR family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MIRYYEQTGLIPPANRRESGYRNYSASDVHMLRFIRRGRDLGFPVAQINELLGLWRDKSRQSAEVKRIATAHITELREKI
DSLEQIASTLQTLIECCSGDDRPDCPILDDLENTADRQQL

Sequences:

>Translated_120_residues
MIRYYEQTGLIPPANRRESGYRNYSASDVHMLRFIRRGRDLGFPVAQINELLGLWRDKSRQSAEVKRIATAHITELREKI
DSLEQIASTLQTLIECCSGDDRPDCPILDDLENTADRQQL
>Mature_120_residues
MIRYYEQTGLIPPANRRESGYRNYSASDVHMLRFIRRGRDLGFPVAQINELLGLWRDKSRQSAEVKRIATAHITELREKI
DSLEQIASTLQTLIECCSGDDRPDCPILDDLENTADRQQL

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=110, Percent_Identity=38.1818181818182, Blast_Score=92, Evalue=6e-21,
Organism=Escherichia coli, GI1789687, Length=118, Percent_Identity=35.5932203389831, Blast_Score=70, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 13835; Mature: 13835

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRYYEQTGLIPPANRRESGYRNYSASDVHMLRFIRRGRDLGFPVAQINELLGLWRDKSR
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCH
QSAEVKRIATAHITELREKIDSLEQIASTLQTLIECCSGDDRPDCPILDDLENTADRQQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MIRYYEQTGLIPPANRRESGYRNYSASDVHMLRFIRRGRDLGFPVAQINELLGLWRDKSR
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCH
QSAEVKRIATAHITELREKIDSLEQIASTLQTLIECCSGDDRPDCPILDDLENTADRQQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]