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The map label for this gene is dsbE [H]

Identifier: 114330089

GI number: 114330089

Start: 58168

End: 58692

Strand: Reverse

Name: dsbE [H]

Synonym: Neut_0058

Alternate gene names: 114330089

Gene position: 58692-58168 (Counterclockwise)

Preceding gene: 114330090

Following gene: 114330088

Centisome position: 2.21

GC content: 52.57

Gene sequence:

>525_bases
ATGAGCCGCTTTGTATGGCCGTTGGTCGGCTTTATCGTACTCGTTGGCTTCCTGGCTTTCGGTTTGACCCTCAAGCCCAG
CGAAGTCCCTTCGCCTTTTATTAACAAGCCGGCACCAAGCTTCACCTTGCCCCAGTTGGCATCCCCAGAAGACACGTTTT
CACCAGAAGCCATGAAAGGCAAAGTGTGGCTGCTGAATGTGTGGGCCTCCTGGTGTTATGCCTGCCTTGAAGAGCATCCC
GTGATTACGGCGTTGGCTAAAACACATGGGGTACCCATTGTCGGCCTTAACTACAAAGATATACGCGGGGAAGCTATTTC
GTGGTTGGAACGCCATGGCAATGGATATGTGTTGTCCGTATCCGATACGCAAGGGCGCGTGGGCATCGACTATGGCGTTT
ATGGCGTGCCCGAGACCTTTGTTATCGATAAGGACGGCTTCATTCGTTACAAGCATATCGGTGCAGTAACCGATAGTGCG
GTACGCGACACGATACTACCGCTGATACGGGAGCTTGAGCAATGA

Upstream 100 bases:

>100_bases
TTTTGATGGCGCTGGGTGGGTTGTTAGCTATTAGTGATCGTCGTTATCGACTTAAGCGCCGCGAACGTAAGGCTGCTTTG
GTCGCAGCAGGAGCCACAGC

Downstream 100 bases:

>100_bases
AACGTTGGTGGCTGACATTATTGTGCGCGGTCATCGCCTTGCCATCGTGGGCGGATAACGGCGCGGCGGAAAAGCGCATG
TTGGATATTGCTGGCGAGCT

Product: periplasmic protein thiol--disulphide oxidoreductase DsbE

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CcmG [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MSRFVWPLVGFIVLVGFLAFGLTLKPSEVPSPFINKPAPSFTLPQLASPEDTFSPEAMKGKVWLLNVWASWCYACLEEHP
VITALAKTHGVPIVGLNYKDIRGEAISWLERHGNGYVLSVSDTQGRVGIDYGVYGVPETFVIDKDGFIRYKHIGAVTDSA
VRDTILPLIRELEQ

Sequences:

>Translated_174_residues
MSRFVWPLVGFIVLVGFLAFGLTLKPSEVPSPFINKPAPSFTLPQLASPEDTFSPEAMKGKVWLLNVWASWCYACLEEHP
VITALAKTHGVPIVGLNYKDIRGEAISWLERHGNGYVLSVSDTQGRVGIDYGVYGVPETFVIDKDGFIRYKHIGAVTDSA
VRDTILPLIRELEQ
>Mature_173_residues
SRFVWPLVGFIVLVGFLAFGLTLKPSEVPSPFINKPAPSFTLPQLASPEDTFSPEAMKGKVWLLNVWASWCYACLEEHPV
ITALAKTHGVPIVGLNYKDIRGEAISWLERHGNGYVLSVSDTQGRVGIDYGVYGVPETFVIDKDGFIRYKHIGAVTDSAV
RDTILPLIRELEQ

Specific function: Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=168, Percent_Identity=41.6666666666667, Blast_Score=134, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 19275; Mature: 19144

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFVWPLVGFIVLVGFLAFGLTLKPSEVPSPFINKPAPSFTLPQLASPEDTFSPEAMKG
CCCHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KVWLLNVWASWCYACLEEHPVITALAKTHGVPIVGLNYKDIRGEAISWLERHGNGYVLSV
CEEEEHHHHHHHHHHHHCCCCEEEHHHHCCCCEEECCHHHHHHHHHHHHHHCCCEEEEEE
SDTQGRVGIDYGVYGVPETFVIDKDGFIRYKHIGAVTDSAVRDTILPLIRELEQ
ECCCCCEEECCCCCCCCCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRFVWPLVGFIVLVGFLAFGLTLKPSEVPSPFINKPAPSFTLPQLASPEDTFSPEAMKG
CCHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KVWLLNVWASWCYACLEEHPVITALAKTHGVPIVGLNYKDIRGEAISWLERHGNGYVLSV
CEEEEHHHHHHHHHHHHCCCCEEEHHHHCCCCEEECCHHHHHHHHHHHHHHCCCEEEEEE
SDTQGRVGIDYGVYGVPETFVIDKDGFIRYKHIGAVTDSAVRDTILPLIRELEQ
ECCCCCEEECCCCCCCCCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA