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The map label for this gene is ycfH [H]

Identifier: 113970004

GI number: 113970004

Start: 1963806

End: 1964606

Strand: Direct

Name: ycfH [H]

Synonym: Shewmr4_1664

Alternate gene names: 113970004

Gene position: 1963806-1964606 (Clockwise)

Preceding gene: 113970003

Following gene: 113970006

Centisome position: 41.73

GC content: 49.44

Gene sequence:

>801_bases
GTGGAAATTGCTGTGCTTATCGATTCACATTGCCATCTCGATCGCCTGAAAGCGGCGCCCGATCAACAAACCTTAGAACT
CATTCTCGCTAACGCTAAGGCGCGCGGTGTCGACTATATGCTCTGTGTCAATGTGCGCCAGCAGGGATTCGAGTCGATGC
GTGACAAGGTTGCTGCTTTCGAGCAAGTGTTTTTATCTTCGGGCGTGCATCCGCTGGATGTGAAAGACGGCCTCGATGTT
GAGCAAATTCGCCGTTTTGCGATGGATCCGAAAGTGGTGGCTATTGGTGAAACCGGCTTAGATTATTTTTATGCCGATGA
AACCAAAGCCCTGCAACAACAGTGTTTTGAGCAACAAATAGCCTTGGCGGTTGAAGTCAATAAGCCGCTGATTGTGCATA
CCCGTGATGCCCGTGAAGACACCATCAACATGCTCAAAGCGGGGCAGGCGGACAAAGTCGGTGGCGTGTTGCATTGCTTT
ACGGAAAACTGGGAAATGGCCAAGGCGGCGATTGACTTAGGTTTTTATATTTCCGTTTCAGGCATTGTGACCTTTAAAAA
TGCTGGTGAGTTAAGAACCGTGATCCGCAAAGTGCCTAAAGATCGTTTATTGGTGGAAACCGATTCGCCTTATCTTGCGC
CTATTCCACACCGTGGACAGGAGAATCAACCTGCCTATGTGCGTGATGTGGCCGAGTTTGTCGCAGAGCTGCGCGCAGAG
CGTTACGAAGAGCTTGCCGAGTACACCAGTGAGAACTTCTTTAATTTGTTTAAAGATGCGGCCCGTTTAATCGGCCGATA
A

Upstream 100 bases:

>100_bases
TTATCCCGAGCTCAGGTTATTTAGTGCTGAGTGATGCCTTAGCGGAATTTGACCTCGATCCCATCGCTGAGTATCCTTGT
GCTCCTTTTTGTTTCTCTGT

Downstream 100 bases:

>100_bases
GACGTGTAGCATTTGCTTGAGTCCGCAAAGACTAAGCCTTAACTTACGCGTTGTGAGTAAAGTGCTAGTCGGTGAAGTTT
GCTCCATAAATAAAAGCTGA

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MEIAVLIDSHCHLDRLKAAPDQQTLELILANAKARGVDYMLCVNVRQQGFESMRDKVAAFEQVFLSSGVHPLDVKDGLDV
EQIRRFAMDPKVVAIGETGLDYFYADETKALQQQCFEQQIALAVEVNKPLIVHTRDAREDTINMLKAGQADKVGGVLHCF
TENWEMAKAAIDLGFYISVSGIVTFKNAGELRTVIRKVPKDRLLVETDSPYLAPIPHRGQENQPAYVRDVAEFVAELRAE
RYEELAEYTSENFFNLFKDAARLIGR

Sequences:

>Translated_266_residues
MEIAVLIDSHCHLDRLKAAPDQQTLELILANAKARGVDYMLCVNVRQQGFESMRDKVAAFEQVFLSSGVHPLDVKDGLDV
EQIRRFAMDPKVVAIGETGLDYFYADETKALQQQCFEQQIALAVEVNKPLIVHTRDAREDTINMLKAGQADKVGGVLHCF
TENWEMAKAAIDLGFYISVSGIVTFKNAGELRTVIRKVPKDRLLVETDSPYLAPIPHRGQENQPAYVRDVAEFVAELRAE
RYEELAEYTSENFFNLFKDAARLIGR
>Mature_266_residues
MEIAVLIDSHCHLDRLKAAPDQQTLELILANAKARGVDYMLCVNVRQQGFESMRDKVAAFEQVFLSSGVHPLDVKDGLDV
EQIRRFAMDPKVVAIGETGLDYFYADETKALQQQCFEQQIALAVEVNKPLIVHTRDAREDTINMLKAGQADKVGGVLHCF
TENWEMAKAAIDLGFYISVSGIVTFKNAGELRTVIRKVPKDRLLVETDSPYLAPIPHRGQENQPAYVRDVAEFVAELRAE
RYEELAEYTSENFFNLFKDAARLIGR

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=278, Percent_Identity=29.4964028776978, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI110349734, Length=278, Percent_Identity=29.4964028776978, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI226061853, Length=285, Percent_Identity=29.1228070175439, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI226061614, Length=265, Percent_Identity=29.4339622641509, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI225903424, Length=128, Percent_Identity=37.5, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI225903439, Length=193, Percent_Identity=29.5336787564767, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI14042943, Length=193, Percent_Identity=29.5336787564767, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI226061595, Length=235, Percent_Identity=29.7872340425532, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1787342, Length=259, Percent_Identity=55.5984555984556, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI48994985, Length=237, Percent_Identity=32.4894514767932, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082439, Length=263, Percent_Identity=31.1787072243346, Blast_Score=117, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17559024, Length=267, Percent_Identity=28.4644194756554, Blast_Score=117, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71980746, Length=269, Percent_Identity=29.368029739777, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=292, Percent_Identity=27.3972602739726, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17565396, Length=147, Percent_Identity=32.6530612244898, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221330018, Length=290, Percent_Identity=28.9655172413793, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24586117, Length=290, Percent_Identity=28.9655172413793, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24648690, Length=291, Percent_Identity=27.4914089347079, Blast_Score=84, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29978; Mature: 29978

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIAVLIDSHCHLDRLKAAPDQQTLELILANAKARGVDYMLCVNVRQQGFESMRDKVAAF
CEEEEEECCCCCHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHH
EQVFLSSGVHPLDVKDGLDVEQIRRFAMDPKVVAIGETGLDYFYADETKALQQQCFEQQI
HHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCEEECCHHHHHHHHHHHHHH
ALAVEVNKPLIVHTRDAREDTINMLKAGQADKVGGVLHCFTENWEMAKAAIDLGFYISVS
EEEEECCCCEEEEECCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHCEEEEEE
GIVTFKNAGELRTVIRKVPKDRLLVETDSPYLAPIPHRGQENQPAYVRDVAEFVAELRAE
EEEEECCCHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
RYEELAEYTSENFFNLFKDAARLIGR
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIAVLIDSHCHLDRLKAAPDQQTLELILANAKARGVDYMLCVNVRQQGFESMRDKVAAF
CEEEEEECCCCCHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHH
EQVFLSSGVHPLDVKDGLDVEQIRRFAMDPKVVAIGETGLDYFYADETKALQQQCFEQQI
HHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCEEECCHHHHHHHHHHHHHH
ALAVEVNKPLIVHTRDAREDTINMLKAGQADKVGGVLHCFTENWEMAKAAIDLGFYISVS
EEEEECCCCEEEEECCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHCEEEEEE
GIVTFKNAGELRTVIRKVPKDRLLVETDSPYLAPIPHRGQENQPAYVRDVAEFVAELRAE
EEEEECCCHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
RYEELAEYTSENFFNLFKDAARLIGR
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]