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The map label for this gene is topA [H]

Identifier: 113969926

GI number: 113969926

Start: 1873183

End: 1875867

Strand: Direct

Name: topA [H]

Synonym: Shewmr4_1585

Alternate gene names: 113969926

Gene position: 1873183-1875867 (Clockwise)

Preceding gene: 113969924

Following gene: 113969928

Centisome position: 39.8

GC content: 48.68

Gene sequence:

>2685_bases
ATGGAGCCAATTTCCACCTTCTTGAGATTTTTTGGCGCAAATCAAACTATGGGTAAATCGCTAGTTATTGTCGAATCACC
GGCCAAAGCTAAGACCATTAATAAATATCTTGGCAAAGAATTCATCGTTAAATCGAGCGTAGGTCACATCCGTGATCTAC
CTACATCTTCTTCATCTGACGGCACTGAAAAGGTGAAATCCGCCGCAGAAGTCAAGAAGATGTCGCCAGAAGAAAAGGCG
CGATACAAAAAGGTGAAAGAACATCAAGCGCTGGTATCGCGTATGGGCGTTAACCCTGAAAAGGGCTGGGCGGCTAAATA
TCAAATCCTACCGGGTAAAGAGAAAGTTGTTAAAGAGCTACAAGCTTTAGCCGATTCTGCTGACCAAATTTATCTCGCAA
CGGACTTAGACCGTGAAGGGGAAGCCATTGCCTGGCACTTGCAAGAGGTGATTGGTGGCGACTCTTCACGGTATCAGCGC
GTGGTGTTTAACGAGATAACCAAATCTGCGATTCAAGAAGCCTTTAGTAAACCTTCAGCCCTTGACACCAATATGGTCAA
TGCCCAACAGGCACGACGCTTTTTAGATCGCGTCGTCGGCTTTATGGTATCACCGCTGTTGTGGAAGAAGGTTGCCCGCG
GTTTATCGGCTGGACGGGTGCAATCTGTGGCTGTGCGCCTAGTGGTTGAACGTGAAAGCGAAATCAAAGCCTTCGTCCCA
GAAGAATTTTGGGATGTGCATGCTCAGCTGAATACGCCTGCCAGCGAAGCGCTGCGCATGGAAGTGGTTAAGTACTTAGA
CTCAGCCTTTGAGCCAACAAATGAGCAGCAAGCATTAGCCGCCGTTCAGGCCTTATCTTCAGCCAGCTTTAAAGTCATTG
CCCGCGAAGATAAAGCCACCCAGAGTAAACCTTCGGCTCCTTTTATTACCTCCACCTTGCAGCAAGCGGCCAGTACTCGC
TTAGGCTTTGGGGTGAAGAAAACCATGATGATGGCGCAGCGTTTGTACGAAGCGGGTCACATCACTTATATGCGTACCGA
CTCCACAAACCTAAGCCAAGAAGCTTTAGACAGTGTGCGTGAGATGATTGGCAAGGAATACGGCGCCAAGTATTTACCTG
CCGAACCGATTCGTTACGGCTCTAAGGAAGGTGCACAAGAGGCGCACGAAGCGATTCGTCCTTCAAATGTGAACGTCGAA
GCCGCAGCTTTAACTGATATGGAACGTGATGCGCAGCGCCTTTACGAGCTTATTTGGCGTCAGTTTGTCTCTTGTCAGAT
GACACCTGCTCAATACGATGCGACTAAACTCACGGTAAACGCGGGCGATTACGAACTGAAAGCGACTGGACGTATCCTGC
GTTTTGACGGTTGGACCCGTGTTCAAACAGCGCTGAAAAAGAAAAACGAAGAAGACAACACACTGCCCTCGGTGAACGAA
GGTGATCTGTTGTCTCTGGTCGAATTAGAGCCCAAACAGCACTTTACCAAGCCGCCCGCCAGATACAGCGAAGCGTCATT
GGTGAAAGAGTTAGAGAAGCGTGGCATTGGCCGGCCATCAACCTATGCCACCATTATTTCGACGATTCAAGAACGGGGTT
ATGTCAAAGTTGAAAACCGCCGTTTCTATGCCGAGAAAATGGGTGAAATCGTTAGCGAACGCCTCGTCGGTAGTTTTGCC
GAGCTGATGAGCTATGATTTTACCGCCAGCATGGAACAGACTCTCGATGATGTTGCCAAAGGTGAACTGGATTGGAAAAA
AGTCCTCGATGGCTTCTATGCCGACTTCACTAAGCAATTAGAGAAGGCTGAGTTAGCACCGGAAGAGGGCGGTATGCGCC
TCAATCAAATGGTGATGACTAATATCAAGTGTCCGACTTGCGGCCGTTCAATGGGGATCCGGACTGGCACAACAGGGGTA
TTCCTTGGTTGTTCGGGCTACGAGTTGCCACCAAAAGAACGCTGCAAAACTACCATGAACTTAACGCCAGGCATTGAAGC
GATAAGCGACAGTGAGGATGCCGAGACCGATGCACTGCGTGCCAAGCACCGCTGTGGTATTTGCGGCACGGCGATGGACA
GTTATCTTATCGACGAAAAACGCAAACTGCATGTTTGTGGTAATAACCCTGTTTGTGAGGGCTATGAGGTCGAAGAAGGG
CAATTTAAGATCAAAGGTTACGAAGGTCCATTAATCGAATGTGACCGTTGCGGCCATGATATGGAACTGAAAAACGGTCG
TTTTGGTAAGTATTTCGGTTGTACTAATTCGGAATGTAAGAATACTCGTAAGTTACTGAAAAACGGTGAAGCGGCACCAC
CAAAAGAAGATCCTATCTATCTGCCAGAGCTGAAATGCAGCAAGTCTGATGCGCATTTTGTGCTACGTGATGGCGCGGCA
GGGATTTTTTTAGCGGCCAGTACTTTCCCTAAATCACGGGAAACCCGCGCACCACTGGTTGAAGAGTTAGTGAAATACCG
TGAACTGTTATGGCCTAAGTATCAGTATCTTGCCGATGCACCTATCGCCGATGATGAGGGCAACAAAGCGGCGGTTAAGT
TTAGCCGTAAGACCAAAGAGCAATACGTGGCGACCGAAGTTGGCGGTAAAGCAACCGGGTGGTCGGCTCATTATGTGAAT
GGTAAATGGGTGACAGAATCGACGGCGAAGAAAGCCAAGAAATAG

Upstream 100 bases:

>100_bases
ATATTATTTTTTTACATTTTTTCAACTTTGATTAAAAAGTGACTCGCTGGTACGTATAAAAGAGGGATTAGCTTGAAACT
CTCAGTGCAACCCTCTATAT

Downstream 100 bases:

>100_bases
TTCCTCGATAATCGTACTATTGTTTGTGTATTTGCAAATGGGCTCACTTTAAGTGGGCCCGTTTTGTTATCTATGCCCGC
AAGATTAAACAGCAATAAAG

Product: DNA topoisomerase I

Products: NA

Alternate protein names: DNA topoisomerase I; Omega-protein; Relaxing enzyme; Swivelase; Untwisting enzyme [H]

Number of amino acids: Translated: 894; Mature: 894

Protein sequence:

>894_residues
MEPISTFLRFFGANQTMGKSLVIVESPAKAKTINKYLGKEFIVKSSVGHIRDLPTSSSSDGTEKVKSAAEVKKMSPEEKA
RYKKVKEHQALVSRMGVNPEKGWAAKYQILPGKEKVVKELQALADSADQIYLATDLDREGEAIAWHLQEVIGGDSSRYQR
VVFNEITKSAIQEAFSKPSALDTNMVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERESEIKAFVP
EEFWDVHAQLNTPASEALRMEVVKYLDSAFEPTNEQQALAAVQALSSASFKVIAREDKATQSKPSAPFITSTLQQAASTR
LGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEALDSVREMIGKEYGAKYLPAEPIRYGSKEGAQEAHEAIRPSNVNVE
AAALTDMERDAQRLYELIWRQFVSCQMTPAQYDATKLTVNAGDYELKATGRILRFDGWTRVQTALKKKNEEDNTLPSVNE
GDLLSLVELEPKQHFTKPPARYSEASLVKELEKRGIGRPSTYATIISTIQERGYVKVENRRFYAEKMGEIVSERLVGSFA
ELMSYDFTASMEQTLDDVAKGELDWKKVLDGFYADFTKQLEKAELAPEEGGMRLNQMVMTNIKCPTCGRSMGIRTGTTGV
FLGCSGYELPPKERCKTTMNLTPGIEAISDSEDAETDALRAKHRCGICGTAMDSYLIDEKRKLHVCGNNPVCEGYEVEEG
QFKIKGYEGPLIECDRCGHDMELKNGRFGKYFGCTNSECKNTRKLLKNGEAAPPKEDPIYLPELKCSKSDAHFVLRDGAA
GIFLAASTFPKSRETRAPLVEELVKYRELLWPKYQYLADAPIADDEGNKAAVKFSRKTKEQYVATEVGGKATGWSAHYVN
GKWVTESTAKKAKK

Sequences:

>Translated_894_residues
MEPISTFLRFFGANQTMGKSLVIVESPAKAKTINKYLGKEFIVKSSVGHIRDLPTSSSSDGTEKVKSAAEVKKMSPEEKA
RYKKVKEHQALVSRMGVNPEKGWAAKYQILPGKEKVVKELQALADSADQIYLATDLDREGEAIAWHLQEVIGGDSSRYQR
VVFNEITKSAIQEAFSKPSALDTNMVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERESEIKAFVP
EEFWDVHAQLNTPASEALRMEVVKYLDSAFEPTNEQQALAAVQALSSASFKVIAREDKATQSKPSAPFITSTLQQAASTR
LGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEALDSVREMIGKEYGAKYLPAEPIRYGSKEGAQEAHEAIRPSNVNVE
AAALTDMERDAQRLYELIWRQFVSCQMTPAQYDATKLTVNAGDYELKATGRILRFDGWTRVQTALKKKNEEDNTLPSVNE
GDLLSLVELEPKQHFTKPPARYSEASLVKELEKRGIGRPSTYATIISTIQERGYVKVENRRFYAEKMGEIVSERLVGSFA
ELMSYDFTASMEQTLDDVAKGELDWKKVLDGFYADFTKQLEKAELAPEEGGMRLNQMVMTNIKCPTCGRSMGIRTGTTGV
FLGCSGYELPPKERCKTTMNLTPGIEAISDSEDAETDALRAKHRCGICGTAMDSYLIDEKRKLHVCGNNPVCEGYEVEEG
QFKIKGYEGPLIECDRCGHDMELKNGRFGKYFGCTNSECKNTRKLLKNGEAAPPKEDPIYLPELKCSKSDAHFVLRDGAA
GIFLAASTFPKSRETRAPLVEELVKYRELLWPKYQYLADAPIADDEGNKAAVKFSRKTKEQYVATEVGGKATGWSAHYVN
GKWVTESTAKKAKK
>Mature_894_residues
MEPISTFLRFFGANQTMGKSLVIVESPAKAKTINKYLGKEFIVKSSVGHIRDLPTSSSSDGTEKVKSAAEVKKMSPEEKA
RYKKVKEHQALVSRMGVNPEKGWAAKYQILPGKEKVVKELQALADSADQIYLATDLDREGEAIAWHLQEVIGGDSSRYQR
VVFNEITKSAIQEAFSKPSALDTNMVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERESEIKAFVP
EEFWDVHAQLNTPASEALRMEVVKYLDSAFEPTNEQQALAAVQALSSASFKVIAREDKATQSKPSAPFITSTLQQAASTR
LGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEALDSVREMIGKEYGAKYLPAEPIRYGSKEGAQEAHEAIRPSNVNVE
AAALTDMERDAQRLYELIWRQFVSCQMTPAQYDATKLTVNAGDYELKATGRILRFDGWTRVQTALKKKNEEDNTLPSVNE
GDLLSLVELEPKQHFTKPPARYSEASLVKELEKRGIGRPSTYATIISTIQERGYVKVENRRFYAEKMGEIVSERLVGSFA
ELMSYDFTASMEQTLDDVAKGELDWKKVLDGFYADFTKQLEKAELAPEEGGMRLNQMVMTNIKCPTCGRSMGIRTGTTGV
FLGCSGYELPPKERCKTTMNLTPGIEAISDSEDAETDALRAKHRCGICGTAMDSYLIDEKRKLHVCGNNPVCEGYEVEEG
QFKIKGYEGPLIECDRCGHDMELKNGRFGKYFGCTNSECKNTRKLLKNGEAAPPKEDPIYLPELKCSKSDAHFVLRDGAA
GIFLAASTFPKSRETRAPLVEELVKYRELLWPKYQYLADAPIADDEGNKAAVKFSRKTKEQYVATEVGGKATGWSAHYVN
GKWVTESTAKKAKK

Specific function: The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another [H]

COG id: COG0550

COG function: function code L; Topoisomerase IA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Toprim domain [H]

Homologues:

Organism=Homo sapiens, GI4507635, Length=500, Percent_Identity=28.4, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI10835218, Length=577, Percent_Identity=25.4766031195841, Blast_Score=130, Evalue=5e-30,
Organism=Escherichia coli, GI1787529, Length=870, Percent_Identity=71.264367816092, Blast_Score=1300, Evalue=0.0,
Organism=Escherichia coli, GI1788061, Length=565, Percent_Identity=24.6017699115044, Blast_Score=119, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI32563869, Length=655, Percent_Identity=23.6641221374046, Blast_Score=129, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17555378, Length=513, Percent_Identity=25.7309941520468, Blast_Score=122, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323263, Length=497, Percent_Identity=25.5533199195171, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24640096, Length=502, Percent_Identity=26.0956175298805, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24585251, Length=590, Percent_Identity=24.7457627118644, Blast_Score=122, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003601
- InterPro:   IPR013497
- InterPro:   IPR013824
- InterPro:   IPR013825
- InterPro:   IPR000380
- InterPro:   IPR003602
- InterPro:   IPR013498
- InterPro:   IPR005733
- InterPro:   IPR013263
- InterPro:   IPR006171 [H]

Pfam domain/function: PF08272 Topo_Zn_Ribbon; PF01131 Topoisom_bac; PF01751 Toprim; PF01396 zf-C4_Topoisom [H]

EC number: =5.99.1.2 [H]

Molecular weight: Translated: 99641; Mature: 99641

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS00396 TOPOISOMERASE_I_PROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPISTFLRFFGANQTMGKSLVIVESPAKAKTINKYLGKEFIVKSSVGHIRDLPTSSSSD
CCHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCHHHHHHCCCCHHHCCCCCCCCC
GTEKVKSAAEVKKMSPEEKARYKKVKEHQALVSRMGVNPEKGWAAKYQILPGKEKVVKEL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHH
QALADSADQIYLATDLDREGEAIAWHLQEVIGGDSSRYQRVVFNEITKSAIQEAFSKPSA
HHHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
LDTNMVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERESEIKAFVP
CCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEECCCHHHHCCC
EEFWDVHAQLNTPASEALRMEVVKYLDSAFEPTNEQQALAAVQALSSASFKVIAREDKAT
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCC
QSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEALDSVR
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHH
EMIGKEYGAKYLPAEPIRYGSKEGAQEAHEAIRPSNVNVEAAALTDMERDAQRLYELIWR
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
QFVSCQMTPAQYDATKLTVNAGDYELKATGRILRFDGWTRVQTALKKKNEEDNTLPSVNE
HHHCCCCCCCCCCCEEEEEECCCEEEEECCEEEEECCHHHHHHHHHHCCCCCCCCCCCCC
GDLLSLVELEPKQHFTKPPARYSEASLVKELEKRGIGRPSTYATIISTIQERGYVKVENR
CCEEEEEECCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEECC
RFYAEKMGEIVSERLVGSFAELMSYDFTASMEQTLDDVAKGELDWKKVLDGFYADFTKQL
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EKAELAPEEGGMRLNQMVMTNIKCPTCGRSMGIRTGTTGVFLGCSGYELPPKERCKTTMN
HHHHCCCCCCCCEEHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHCEECC
LTPGIEAISDSEDAETDALRAKHRCGICGTAMDSYLIDEKRKLHVCGNNPVCEGYEVEEG
CCCCCHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCCCCCEEECCC
QFKIKGYEGPLIECDRCGHDMELKNGRFGKYFGCTNSECKNTRKLLKNGEAAPPKEDPIY
EEEEECCCCCEEEHHCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCCCCCEE
LPELKCSKSDAHFVLRDGAAGIFLAASTFPKSRETRAPLVEELVKYRELLWPKYQYLADA
CCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCC
PIADDEGNKAAVKFSRKTKEQYVATEVGGKATGWSAHYVNGKWVTESTAKKAKK
CCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCEEEEECCEEECCHHHHHCCC
>Mature Secondary Structure
MEPISTFLRFFGANQTMGKSLVIVESPAKAKTINKYLGKEFIVKSSVGHIRDLPTSSSSD
CCHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCHHHHHHCCCCHHHCCCCCCCCC
GTEKVKSAAEVKKMSPEEKARYKKVKEHQALVSRMGVNPEKGWAAKYQILPGKEKVVKEL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHH
QALADSADQIYLATDLDREGEAIAWHLQEVIGGDSSRYQRVVFNEITKSAIQEAFSKPSA
HHHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
LDTNMVNAQQARRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVERESEIKAFVP
CCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEECCCHHHHCCC
EEFWDVHAQLNTPASEALRMEVVKYLDSAFEPTNEQQALAAVQALSSASFKVIAREDKAT
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCC
QSKPSAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQEALDSVR
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHH
EMIGKEYGAKYLPAEPIRYGSKEGAQEAHEAIRPSNVNVEAAALTDMERDAQRLYELIWR
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
QFVSCQMTPAQYDATKLTVNAGDYELKATGRILRFDGWTRVQTALKKKNEEDNTLPSVNE
HHHCCCCCCCCCCCEEEEEECCCEEEEECCEEEEECCHHHHHHHHHHCCCCCCCCCCCCC
GDLLSLVELEPKQHFTKPPARYSEASLVKELEKRGIGRPSTYATIISTIQERGYVKVENR
CCEEEEEECCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEECC
RFYAEKMGEIVSERLVGSFAELMSYDFTASMEQTLDDVAKGELDWKKVLDGFYADFTKQL
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EKAELAPEEGGMRLNQMVMTNIKCPTCGRSMGIRTGTTGVFLGCSGYELPPKERCKTTMN
HHHHCCCCCCCCEEHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHCEECC
LTPGIEAISDSEDAETDALRAKHRCGICGTAMDSYLIDEKRKLHVCGNNPVCEGYEVEEG
CCCCCHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCCCCCEEECCC
QFKIKGYEGPLIECDRCGHDMELKNGRFGKYFGCTNSECKNTRKLLKNGEAAPPKEDPIY
EEEEECCCCCEEEHHCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCCCCCEE
LPELKCSKSDAHFVLRDGAAGIFLAASTFPKSRETRAPLVEELVKYRELLWPKYQYLADA
CCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCC
PIADDEGNKAAVKFSRKTKEQYVATEVGGKATGWSAHYVNGKWVTESTAKKAKK
CCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCEEEEECCEEECCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3029379; 9097039; 9278503; 3032952; 8114910; 7779808 [H]