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The map label for this gene is fadR [H]

Identifier: 113969910

GI number: 113969910

Start: 1850601

End: 1851326

Strand: Direct

Name: fadR [H]

Synonym: Shewmr4_1568

Alternate gene names: 113969910

Gene position: 1850601-1851326 (Clockwise)

Preceding gene: 113969906

Following gene: 113969914

Centisome position: 39.32

GC content: 45.45

Gene sequence:

>726_bases
ATGATTATCAATGCCAAAGGACCTGCAAGTTTTGCAGAGAAGTATATTGTAAGATCGATTTGGGAAAACAAGTTTCCCCC
AGGGTCCATTTTACCGGCTGAACGTGAGCTTTCTGAATTGATTGGCGTAACACGCACGACACTGCGTGAAGTTTTGCAAC
GCTTAGCCCGTGATGGTTGGTTGAAAATCCAACATGGTAAACCGACTCGGGTAAACAATTTTTGGGAAACCTCAGGCCTT
AACATTCTCGAGACGATTGCAGATCTCAACCCTGAAGGCTTCCCTGTGCTGGTGGACCAATTGCTGTCGGCTCGAACCAA
TGTGAGCGCGATTTATTTCCGTGGTGCACTGCGCAACAGCCCTGACACCGCCGTTGAAGTGTTAGCACAAATTCATCAAT
TAGAAGATACGGCAGAATCCTTCGCCGAGTATGACTACTTATTGCATCATACTTTAGCTTTCTCTTCTGGCAATCCGCTG
TATGTGTTGATCTTAAATGGCTTTAAAGGTCTGTATAGCCGAGTCGGTCGTTACTATTTCAGTAGCCCAGAGGCGCGCCA
GTTAGCGCTGAACTTCTATAAAGAACTGGAAGTATTAGCCAAAGCTAAAAATTATGTTGATGTGCCTGCATTAATGCGCA
CTTACGGTATCAACAGTGGCAAAATGTGGTTGCAATTGCGTGACGATATGCCGACTTCAATTGCCCTGCAAGAAGCCAAC
TCTTAA

Upstream 100 bases:

>100_bases
CGGTGATTTTAAGGTGAGCTGCAGTCAATGGTTTCCATTTTTTACCGCTCTGGTATGATCAGTGACCATTATAAAGCACA
ACAACTGGAAAAGTGGGCTG

Downstream 100 bases:

>100_bases
GTAAAAATGCGCCTTGTTAAACGAAAAAGCCGTTTCATTGAGAAACGGCTTTTTGCTTTTTAGTCAGTGAGATGCTCAAT
CGGCCTTAGGTTGTTCTGGG

Product: fatty acid metabolism regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLKIQHGKPTRVNNFWETSGL
NILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRNSPDTAVEVLAQIHQLEDTAESFAEYDYLLHHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFSSPEARQLALNFYKELEVLAKAKNYVDVPALMRTYGINSGKMWLQLRDDMPTSIALQEAN
S

Sequences:

>Translated_241_residues
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLKIQHGKPTRVNNFWETSGL
NILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRNSPDTAVEVLAQIHQLEDTAESFAEYDYLLHHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFSSPEARQLALNFYKELEVLAKAKNYVDVPALMRTYGINSGKMWLQLRDDMPTSIALQEAN
S
>Mature_241_residues
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLKIQHGKPTRVNNFWETSGL
NILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRNSPDTAVEVLAQIHQLEDTAESFAEYDYLLHHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFSSPEARQLALNFYKELEVLAKAKNYVDVPALMRTYGINSGKMWLQLRDDMPTSIALQEAN
S

Specific function: Multifunctional regulator of fatty acid metabolism [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787436, Length=237, Percent_Identity=61.6033755274262, Blast_Score=311, Evalue=3e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014178
- InterPro:   IPR008920
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07840 FadR_C; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27211; Mature: 27211

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGW
CEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LKIQHGKPTRVNNFWETSGLNILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRNS
EEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHEEEECHHCCC
PDTAVEVLAQIHQLEDTAESFAEYDYLLHHTLAFSSGNPLYVLILNGFKGLYSRVGRYYF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHC
SSPEARQLALNFYKELEVLAKAKNYVDVPALMRTYGINSGKMWLQLRDDMPTSIALQEAN
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCC
S
C
>Mature Secondary Structure
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGW
CEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LKIQHGKPTRVNNFWETSGLNILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRNS
EEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHEEEECHHCCC
PDTAVEVLAQIHQLEDTAESFAEYDYLLHHTLAFSSGNPLYVLILNGFKGLYSRVGRYYF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHC
SSPEARQLALNFYKELEVLAKAKNYVDVPALMRTYGINSGKMWLQLRDDMPTSIALQEAN
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA; DNA [C]

Specific reaction: Activates transcription of at least two genes required for unsaturated fatty acid biosynthesis; activates the iclR gene encoding the transcription regulator of the aceBAKoperon which in turn encodes the glyoxylate shunt enzymes Protein + DNA = Protein-DN

General reaction: NA

Inhibitor: Fatty acyl CoA compounds [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA