Click here to switch to the map view.

The map label for this gene is speA [H]

Identifier: 113969899

GI number: 113969899

Start: 1837558

End: 1839471

Strand: Direct

Name: speA [H]

Synonym: Shewmr4_1557

Alternate gene names: 113969899

Gene position: 1837558-1839471 (Clockwise)

Preceding gene: 113969898

Following gene: 113969900

Centisome position: 39.04

GC content: 47.13

Gene sequence:

>1914_bases
ATGAATGATTGGTCTATTGATGCTGCTCGTGCTGGGTACAACGTTACCCACTGGAGCCAAGGGTTTTATGGGATCAGCGA
CCAAGGTGAGGTGACAGTGTCGCCGGATCCTAAGAATCCTGATCACAAGATTGGCTTAAATGAGCTAGCAAAAGACATGG
TTAAAGCGGGGGTCGCTTTACCTGTATTAGTTCGTTTCCCGCAAATTCTGCACCACAGAGTGAACAGTTTGTGCCAAGCA
TTCGACCAAGCGATACAAAAATATGAGTATCAGGCGGACTATTTGCTGGTTTACCCCATTAAAGTAAACCAACAAAAAAC
TGTGGTAGAAGAGATCCTTGCGAGCCAAGCATCAAAAGAAGTTCCACAATTAGGCCTAGAAGCCGGCAGTAAGCCAGAAT
TAATGGCCGTACTGGCCATGGCGCAAAAAGCCAGTTCAGTGATTGTATGTAACGGTTATAAAGATAACGAATACATCCGT
TTAGCCTTAATTGGTGAAAAGTTAGGCCATAAGGTCTACATCGTTTTAGAAAAACTGTCTGAGCTGAAGATGGTGTTGGC
CGAATCTAAGCGCTTAGGGGTGAAACCTCGCTTAGGTCTACGTGCGCGCCTTGCATTCCAAGGTAAAGGCAAGTGGCAAG
CCAGCGGTGGCGAAAAGTCTAAGTTCGGTTTATCTGCGGCGCAGATTTTAACTGTGGTAGATCAGTTAAAAGAAAACGAC
ATGTTGGATTCGCTGCAGTTATTGCACTTCCACTTAGGTTCGCAAATCGCGAACATCCGCGATATTCGTCAGGGTGTGAG
TGAAGCGGCGCGTTTCTACTGTGAATTACGCGAGTTAGGCGCCAGCATCAACTGCTTCGACGTCGGCGGTGGTTTAGCGG
TGGATTACGACGGCACACGTAGCCAAAGTAACAACTCAATGAACTATGGCTTAAGCGAATACGCCAATAACATCGTTAAC
GTGCTTACCGATATCTGTAATGAATACGAGCAACCTATGCCACGTATTATTTCAGAATCAGGCCGTCACTTAACGGCGCA
CCATGCAGTGCTGATCACCGACGTGATTGGTACTGAAGCCTATCAGGTAGAAGATATCCAGCCGCCAGCGGAAGAATCGC
CACAACTGCTGCACAACATGTGGCAATCGTGGACTGAGTTGAGCGGCCGCGCTGATCAACGTGCACTGATTGAGATTTAC
CACGATAGCCAAAGCGACTTGCAAGAAGCGCAATCACTGTTTGCCTTGGGTCAATTAAGCTTGGCGGAGCGTGCGTGGGC
TGAACAGGCAAACCTGCGTGTTTGTCACGAAGTGCAAGGTTTGTTAAGCACCAAAAACCGTTACCACAGACCGATCATCG
ATGAGTTAAACGAAAAGTTAGCCGATAAGTTCTTCGTTAACTTCTCACTATTCCAATCGTTACCGGATGCTTGGGGTATC
GATCAGGTGTTCCCTGTACTGCCGCTGTCAGGTTTAGACAAAGCGCCAGAGCGCCGCGCTGTTATGTTGGACATTACCTG
TGACTCTGACGGTATTGTTGACCAATACGTAGACGGTCAAGGGATTGAAACCACGCTGCCAGTTCCGGCTTGGAGCGCAG
AGAGCCCTTACTTGATGGGCTTCTTTATGGTGGGCGCATATCAGGAAATTTTAGGCGATATGCACAACCTGTTTGGTGAT
ACTAACTCTGCGGTGGTCAGCATCGAAGAAAACGGTATGACTAATATTGAGTCGGTACTTGCCGGTGACACAGTCGCTGA
CGTACTTCGTTATGTTAACTTAGATGCGGTCGACTTTATGCGCACCTACGAAGAGTTAGTGAACCAGCATATTGTTGAAG
AAGAACGCGCGCAAATTTTAGAAGAATTACAAGTGGGCCTAAAAGGTTACACTTATTTAGAAGATTTTTCTTAA

Upstream 100 bases:

>100_bases
TTCAGGTAAGCTTGTGTTTTACCTGGGTTTGTCGAACGGGCGGTCGTGCAAGATTGCAATGGCCGTTTAACCCATTTTTT
TATAGACGGGCTAAATAAAA

Downstream 100 bases:

>100_bases
TATTGAGTGTGTTAAAAAAGTCAGCCTAGGGTAACTTAGGCTGACTTTTGTTTTTTATAGCCCGTTGTTTTTTGCTCGCG
AGTTGCATGGCTGTCACCTT

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MNDWSIDAARAGYNVTHWSQGFYGISDQGEVTVSPDPKNPDHKIGLNELAKDMVKAGVALPVLVRFPQILHHRVNSLCQA
FDQAIQKYEYQADYLLVYPIKVNQQKTVVEEILASQASKEVPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDNEYIR
LALIGEKLGHKVYIVLEKLSELKMVLAESKRLGVKPRLGLRARLAFQGKGKWQASGGEKSKFGLSAAQILTVVDQLKEND
MLDSLQLLHFHLGSQIANIRDIRQGVSEAARFYCELRELGASINCFDVGGGLAVDYDGTRSQSNNSMNYGLSEYANNIVN
VLTDICNEYEQPMPRIISESGRHLTAHHAVLITDVIGTEAYQVEDIQPPAEESPQLLHNMWQSWTELSGRADQRALIEIY
HDSQSDLQEAQSLFALGQLSLAERAWAEQANLRVCHEVQGLLSTKNRYHRPIIDELNEKLADKFFVNFSLFQSLPDAWGI
DQVFPVLPLSGLDKAPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPAWSAESPYLMGFFMVGAYQEILGDMHNLFGD
TNSAVVSIEENGMTNIESVLAGDTVADVLRYVNLDAVDFMRTYEELVNQHIVEEERAQILEELQVGLKGYTYLEDFS

Sequences:

>Translated_637_residues
MNDWSIDAARAGYNVTHWSQGFYGISDQGEVTVSPDPKNPDHKIGLNELAKDMVKAGVALPVLVRFPQILHHRVNSLCQA
FDQAIQKYEYQADYLLVYPIKVNQQKTVVEEILASQASKEVPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDNEYIR
LALIGEKLGHKVYIVLEKLSELKMVLAESKRLGVKPRLGLRARLAFQGKGKWQASGGEKSKFGLSAAQILTVVDQLKEND
MLDSLQLLHFHLGSQIANIRDIRQGVSEAARFYCELRELGASINCFDVGGGLAVDYDGTRSQSNNSMNYGLSEYANNIVN
VLTDICNEYEQPMPRIISESGRHLTAHHAVLITDVIGTEAYQVEDIQPPAEESPQLLHNMWQSWTELSGRADQRALIEIY
HDSQSDLQEAQSLFALGQLSLAERAWAEQANLRVCHEVQGLLSTKNRYHRPIIDELNEKLADKFFVNFSLFQSLPDAWGI
DQVFPVLPLSGLDKAPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPAWSAESPYLMGFFMVGAYQEILGDMHNLFGD
TNSAVVSIEENGMTNIESVLAGDTVADVLRYVNLDAVDFMRTYEELVNQHIVEEERAQILEELQVGLKGYTYLEDFS
>Mature_637_residues
MNDWSIDAARAGYNVTHWSQGFYGISDQGEVTVSPDPKNPDHKIGLNELAKDMVKAGVALPVLVRFPQILHHRVNSLCQA
FDQAIQKYEYQADYLLVYPIKVNQQKTVVEEILASQASKEVPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDNEYIR
LALIGEKLGHKVYIVLEKLSELKMVLAESKRLGVKPRLGLRARLAFQGKGKWQASGGEKSKFGLSAAQILTVVDQLKEND
MLDSLQLLHFHLGSQIANIRDIRQGVSEAARFYCELRELGASINCFDVGGGLAVDYDGTRSQSNNSMNYGLSEYANNIVN
VLTDICNEYEQPMPRIISESGRHLTAHHAVLITDVIGTEAYQVEDIQPPAEESPQLLHNMWQSWTELSGRADQRALIEIY
HDSQSDLQEAQSLFALGQLSLAERAWAEQANLRVCHEVQGLLSTKNRYHRPIIDELNEKLADKFFVNFSLFQSLPDAWGI
DQVFPVLPLSGLDKAPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPAWSAESPYLMGFFMVGAYQEILGDMHNLFGD
TNSAVVSIEENGMTNIESVLAGDTVADVLRYVNLDAVDFMRTYEELVNQHIVEEERAQILEELQVGLKGYTYLEDFS

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=624, Percent_Identity=57.3717948717949, Blast_Score=740, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 71020; Mature: 71020

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDWSIDAARAGYNVTHWSQGFYGISDQGEVTVSPDPKNPDHKIGLNELAKDMVKAGVAL
CCCCCCCHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCHH
PVLVRFPQILHHRVNSLCQAFDQAIQKYEYQADYLLVYPIKVNQQKTVVEEILASQASKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
VPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDNEYIRLALIGEKLGHKVYIVLEKLS
HHHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECHHHCCEEEHHHHHHH
ELKMVLAESKRLGVKPRLGLRARLAFQGKGKWQASGGEKSKFGLSAAQILTVVDQLKEND
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEECCCCCCCHHCHHHHHHHHHHHHHHHCC
MLDSLQLLHFHLGSQIANIRDIRQGVSEAARFYCELRELGASINCFDVGGGLAVDYDGTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCCCC
SQSNNSMNYGLSEYANNIVNVLTDICNEYEQPMPRIISESGRHLTAHHAVLITDVIGTEA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEHHHEEEEHHHCCCC
YQVEDIQPPAEESPQLLHNMWQSWTELSGRADQRALIEIYHDSQSDLQEAQSLFALGQLS
EEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEHHEECCCHHHHHHHHHHHHHHHHH
LAERAWAEQANLRVCHEVQGLLSTKNRYHRPIIDELNEKLADKFFVNFSLFQSLPDAWGI
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DQVFPVLPLSGLDKAPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPAWSAESPYLMG
HHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHCCCCCCCCEECCCCCCCCCCCHHHH
FFMVGAYQEILGDMHNLFGDTNSAVVSIEENGMTNIESVLAGDTVADVLRYVNLDAVDFM
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHCCHHHHHH
RTYEELVNQHIVEEERAQILEELQVGLKGYTYLEDFS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNDWSIDAARAGYNVTHWSQGFYGISDQGEVTVSPDPKNPDHKIGLNELAKDMVKAGVAL
CCCCCCCHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCHH
PVLVRFPQILHHRVNSLCQAFDQAIQKYEYQADYLLVYPIKVNQQKTVVEEILASQASKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
VPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDNEYIRLALIGEKLGHKVYIVLEKLS
HHHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECHHHCCEEEHHHHHHH
ELKMVLAESKRLGVKPRLGLRARLAFQGKGKWQASGGEKSKFGLSAAQILTVVDQLKEND
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEECCCCCCCHHCHHHHHHHHHHHHHHHCC
MLDSLQLLHFHLGSQIANIRDIRQGVSEAARFYCELRELGASINCFDVGGGLAVDYDGTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCCCC
SQSNNSMNYGLSEYANNIVNVLTDICNEYEQPMPRIISESGRHLTAHHAVLITDVIGTEA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEHHHEEEEHHHCCCC
YQVEDIQPPAEESPQLLHNMWQSWTELSGRADQRALIEIYHDSQSDLQEAQSLFALGQLS
EEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEHHEECCCHHHHHHHHHHHHHHHHH
LAERAWAEQANLRVCHEVQGLLSTKNRYHRPIIDELNEKLADKFFVNFSLFQSLPDAWGI
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DQVFPVLPLSGLDKAPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPAWSAESPYLMG
HHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHCCCCCCCCEECCCCCCCCCCCHHHH
FFMVGAYQEILGDMHNLFGDTNSAVVSIEENGMTNIESVLAGDTVADVLRYVNLDAVDFM
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHCCHHHHHH
RTYEELVNQHIVEEERAQILEELQVGLKGYTYLEDFS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA