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The map label for this gene is uvrC [H]

Identifier: 113969890

GI number: 113969890

Start: 1827991

End: 1829820

Strand: Direct

Name: uvrC [H]

Synonym: Shewmr4_1548

Alternate gene names: 113969890

Gene position: 1827991-1829820 (Clockwise)

Preceding gene: 113969889

Following gene: 113969891

Centisome position: 38.84

GC content: 49.4

Gene sequence:

>1830_bases
ATGTCGACAGGTTTTAACGCCCAGAGTTTTTTACGCACAGTTTCATCCTCTGCAGGGGTTTATCGCATGTATGACGTCAA
AGGTGACGTCATCTATGTGGGTAAAGCTAAAGATCTTAAGAAGCGCTTATCCTCCTATTTTCGTAAAAACCTTGGGAATG
TGAAAACCCAGGCGCTGGTGTCCCATATCCATCATATCGATGTGACGCTGACCCACAGTGAGACCGATGCGCTGCTGCTT
GAAAATGACTATATCAAGCAGTACATGCCCAAATACAATGTGTTACTGCGGGACGATAAGTCATACCCTTATATTTTCTT
GAGTCAACACGAGCATCCACGCCTTGCATACCATCGCGGGCCGCAGCGGGAGAAGGGCTATTACTTTGGGCCTTATCCCA
ATGGCGGCGCGGTGCGCGAAAGTTTGCACTTGATGCAAAAGCTGTTTCCTATTCGCCAGTGTGATGATCTCTATTATAAA
TCCCGCACTCGTCCCTGCCTGCAATACCAGTTATCCCGTTGCAGCGCGCCTTGCGTCGGTAAGGTCAGTAATGCGGAGTA
TGATGAGCAGGTTAAACTCGCCAGTTTGTTCCTAAAGGGAAAAGATAAGCAAGTTATCAGTGAGCTCGTGGCTAAGATGG
AAGAGGCCGCCGAGCAGCAAGCCTATGAGCAAGCCGCGCGCTTTCGCGATCAAATTATGGCGCTGCGCCGCGTGGCCGAG
CAGCAAGAAGTCTCGGGCAATACCGGGGATATGGATGTTATCGGCGTGCATTACGCCTCGGGCATCGCTTGTTTTCACCT
GTTATTTATCCGCGAAGGTAAAATTTTTGGTAGCCGCAGCTATTATCCAACGGTGCCCGCGCAAACGGATATTGAAGAAG
TCTTACGTTCCTTCCTGCTACAGTTTTATTTAAATGCCGATATTCAACGCACCATTCCTAAGGAAGTGGTGATAAGCCAT
CACTTTGAAGAATTGCATGAGCTAGAGGCGGCCGTCTCTGAGGCGTTAAACAAAAAGTTCAGCATCAAAACCAATGTGCG
CGCCGATAGGGCAAGCTTTTTGCGCCTTGCGCTAACTAATGCCACCAATGCGGTGATGACGCGTCTGTCCCATAAAAACA
CCGTTGAACAACGTTTTGTCTTGTTGGAGGAGATTCTCGAACTCAATGCGCCGATCCAGCGCATGGAGTGTTTCGATATC
AGCCATACCATGGGGGAGAGTACGGTAGCCTCTTGCGTGGTGTTTAACCGCGAGGGGCCACATAAGGCCGAATACCGACG
TTACAATATCGAAGGCATTACGCCCGGCGATGATTATGCCGCGATGAAACAAGCCATTAGTCGTCGATTTGATAAAATCG
ATGCCAGCGGCAAAATTCCTGACATCTTATTTATCGACGGTGGTTTGGGTCAGCTGCGTATCGCGCAGCAAATAGTGGAT
GAGAAATTCGTCAATTTAGATAAAGCGCCGCAACTGATTGGGGTGGCAAAGGGAGAGAGCCGTAAACCTGGGCTTGAAAC
CTTAATCTTTGGCGATACTGAAAGTAGCTTTTCCCTTGAAGATGACTCGCCAGCGCTGCACCTTATTCAACATATTCGCG
ATGAGTCTCACCGCTTTGCGATTACAGGCCATCGCAATCGGCGCCAGAAAACCCGTAACACCTCGACGCTCGAATCCATT
CCCGGCATTGGTCCTAAGCGGCGCAAGGCGTTATTGCAACATCTTGGTGGTTTACAGGAAGTGAAGGGCGCGAGTGTGGC
CGAATTAGCGAAAGTGCCTGGTATTAGCATAGAAATGGCACAAACCATTCATGATGCATTGCGAGGGTGA

Upstream 100 bases:

>100_bases
GTGTCAATGGTTCTAGCATTAATTAAGTGTTAGTTGTGAGTGTGAAGACGATTTATCAAATTGTGTTGAAGACGGTGAGT
AAAAGAGTGGGTGTATAACG

Downstream 100 bases:

>100_bases
TAAATTTAAGGCAAGATTGGCGCTGCTTTTGACTAACTGGTTCGATCATGCCGTTTAACTTACCTATAGCATTAACCCTT
TTCAGGCTTTTTTTACTGCC

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MSTGFNAQSFLRTVSSSAGVYRMYDVKGDVIYVGKAKDLKKRLSSYFRKNLGNVKTQALVSHIHHIDVTLTHSETDALLL
ENDYIKQYMPKYNVLLRDDKSYPYIFLSQHEHPRLAYHRGPQREKGYYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYK
SRTRPCLQYQLSRCSAPCVGKVSNAEYDEQVKLASLFLKGKDKQVISELVAKMEEAAEQQAYEQAARFRDQIMALRRVAE
QQEVSGNTGDMDVIGVHYASGIACFHLLFIREGKIFGSRSYYPTVPAQTDIEEVLRSFLLQFYLNADIQRTIPKEVVISH
HFEELHELEAAVSEALNKKFSIKTNVRADRASFLRLALTNATNAVMTRLSHKNTVEQRFVLLEEILELNAPIQRMECFDI
SHTMGESTVASCVVFNREGPHKAEYRRYNIEGITPGDDYAAMKQAISRRFDKIDASGKIPDILFIDGGLGQLRIAQQIVD
EKFVNLDKAPQLIGVAKGESRKPGLETLIFGDTESSFSLEDDSPALHLIQHIRDESHRFAITGHRNRRQKTRNTSTLESI
PGIGPKRRKALLQHLGGLQEVKGASVAELAKVPGISIEMAQTIHDALRG

Sequences:

>Translated_609_residues
MSTGFNAQSFLRTVSSSAGVYRMYDVKGDVIYVGKAKDLKKRLSSYFRKNLGNVKTQALVSHIHHIDVTLTHSETDALLL
ENDYIKQYMPKYNVLLRDDKSYPYIFLSQHEHPRLAYHRGPQREKGYYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYK
SRTRPCLQYQLSRCSAPCVGKVSNAEYDEQVKLASLFLKGKDKQVISELVAKMEEAAEQQAYEQAARFRDQIMALRRVAE
QQEVSGNTGDMDVIGVHYASGIACFHLLFIREGKIFGSRSYYPTVPAQTDIEEVLRSFLLQFYLNADIQRTIPKEVVISH
HFEELHELEAAVSEALNKKFSIKTNVRADRASFLRLALTNATNAVMTRLSHKNTVEQRFVLLEEILELNAPIQRMECFDI
SHTMGESTVASCVVFNREGPHKAEYRRYNIEGITPGDDYAAMKQAISRRFDKIDASGKIPDILFIDGGLGQLRIAQQIVD
EKFVNLDKAPQLIGVAKGESRKPGLETLIFGDTESSFSLEDDSPALHLIQHIRDESHRFAITGHRNRRQKTRNTSTLESI
PGIGPKRRKALLQHLGGLQEVKGASVAELAKVPGISIEMAQTIHDALRG
>Mature_608_residues
STGFNAQSFLRTVSSSAGVYRMYDVKGDVIYVGKAKDLKKRLSSYFRKNLGNVKTQALVSHIHHIDVTLTHSETDALLLE
NDYIKQYMPKYNVLLRDDKSYPYIFLSQHEHPRLAYHRGPQREKGYYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYKS
RTRPCLQYQLSRCSAPCVGKVSNAEYDEQVKLASLFLKGKDKQVISELVAKMEEAAEQQAYEQAARFRDQIMALRRVAEQ
QEVSGNTGDMDVIGVHYASGIACFHLLFIREGKIFGSRSYYPTVPAQTDIEEVLRSFLLQFYLNADIQRTIPKEVVISHH
FEELHELEAAVSEALNKKFSIKTNVRADRASFLRLALTNATNAVMTRLSHKNTVEQRFVLLEEILELNAPIQRMECFDIS
HTMGESTVASCVVFNREGPHKAEYRRYNIEGITPGDDYAAMKQAISRRFDKIDASGKIPDILFIDGGLGQLRIAQQIVDE
KFVNLDKAPQLIGVAKGESRKPGLETLIFGDTESSFSLEDDSPALHLIQHIRDESHRFAITGHRNRRQKTRNTSTLESIP
GIGPKRRKALLQHLGGLQEVKGASVAELAKVPGISIEMAQTIHDALRG

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=610, Percent_Identity=57.8688524590164, Blast_Score=733, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 68900; Mature: 68768

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGFNAQSFLRTVSSSAGVYRMYDVKGDVIYVGKAKDLKKRLSSYFRKNLGNVKTQALV
CCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHCCHHHHHHH
SHIHHIDVTLTHSETDALLLENDYIKQYMPKYNVLLRDDKSYPYIFLSQHEHPRLAYHRG
HHHHHEEEEEEECCCCEEEEECHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCHHHCCC
PQREKGYYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYKSRTRPCLQYQLSRCSAPCVG
CCCCCCEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
KVSNAEYDEQVKLASLFLKGKDKQVISELVAKMEEAAEQQAYEQAARFRDQIMALRRVAE
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQEVSGNTGDMDVIGVHYASGIACFHLLFIREGKIFGSRSYYPTVPAQTDIEEVLRSFLL
HHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHH
QFYLNADIQRTIPKEVVISHHFEELHELEAAVSEALNKKFSIKTNVRADRASFLRLALTN
HHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHH
ATNAVMTRLSHKNTVEQRFVLLEEILELNAPIQRMECFDISHTMGESTVASCVVFNREGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHEEEECCCCC
HKAEYRRYNIEGITPGDDYAAMKQAISRRFDKIDASGKIPDILFIDGGLGQLRIAQQIVD
CCCHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHH
EKFVNLDKAPQLIGVAKGESRKPGLETLIFGDTESSFSLEDDSPALHLIQHIRDESHRFA
HHHHCCCCCCCEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
ITGHRNRRQKTRNTSTLESIPGIGPKRRKALLQHLGGLQEVKGASVAELAKVPGISIEMA
EECCCHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHCCCCCHHHH
QTIHDALRG
HHHHHHHCC
>Mature Secondary Structure 
STGFNAQSFLRTVSSSAGVYRMYDVKGDVIYVGKAKDLKKRLSSYFRKNLGNVKTQALV
CCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHCCHHHHHHH
SHIHHIDVTLTHSETDALLLENDYIKQYMPKYNVLLRDDKSYPYIFLSQHEHPRLAYHRG
HHHHHEEEEEEECCCCEEEEECHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCHHHCCC
PQREKGYYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYKSRTRPCLQYQLSRCSAPCVG
CCCCCCEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
KVSNAEYDEQVKLASLFLKGKDKQVISELVAKMEEAAEQQAYEQAARFRDQIMALRRVAE
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQEVSGNTGDMDVIGVHYASGIACFHLLFIREGKIFGSRSYYPTVPAQTDIEEVLRSFLL
HHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHH
QFYLNADIQRTIPKEVVISHHFEELHELEAAVSEALNKKFSIKTNVRADRASFLRLALTN
HHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHH
ATNAVMTRLSHKNTVEQRFVLLEEILELNAPIQRMECFDISHTMGESTVASCVVFNREGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHEEEECCCCC
HKAEYRRYNIEGITPGDDYAAMKQAISRRFDKIDASGKIPDILFIDGGLGQLRIAQQIVD
CCCHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHH
EKFVNLDKAPQLIGVAKGESRKPGLETLIFGDTESSFSLEDDSPALHLIQHIRDESHRFA
HHHHCCCCCCCEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
ITGHRNRRQKTRNTSTLESIPGIGPKRRKALLQHLGGLQEVKGASVAELAKVPGISIEMA
EECCCHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHCCCCCHHHH
QTIHDALRG
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA