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The map label for this gene is cheA [H]

Identifier: 113969645

GI number: 113969645

Start: 1508460

End: 1510742

Strand: Direct

Name: cheA [H]

Synonym: Shewmr4_1302

Alternate gene names: 113969645

Gene position: 1508460-1510742 (Clockwise)

Preceding gene: 113969644

Following gene: 113969646

Centisome position: 32.05

GC content: 49.45

Gene sequence:

>2283_bases
ATGGCCTTTGATGTAGATGAAGAGATACTCCAGGACTTTTTAATTGAAGCGGGCGAAATTCTTGAGTTGCTGCAAGAGCA
GCTGGTCGCGCTTGAAAACAATCCTGATGATACTAACTTGCTAAATGCCATTTTCAGGGGGTTTCATACTGTAAAGGGCG
GTGCGGGTTTCCTTAGTCTCACTCCCATGGTGGATGTCTGTCACGAAGCAGAAAACACCTTCGATTTATTACGCACAGGC
AAGCGCAGTGTCTCCGCCGAGTTAATGGACATCATTCTTCAAGCTGTCGATGCGATTAACACTATGTTTGCTCAAACCCA
ACAAGGCGAGCAACAAGATCCCGCCGATCCTGCATTATTGGCTAAATTAAAAATGCTGAGCTCCGGTGAGCCGCTTCCTT
CCGAATCAGGCCAAAGTCATGCCGAAGCTGAGTCACTGCCTGAACCAGAACCTGTTATAGAAACTGTGGTTGAAGTCGCC
GCAGTTGAAGAAATGCCGATTGAGAAGTCAGAGCTATCAGATTCCAGTATTGATGAAATCGATGAAGCGGAGTTTGAAGC
ATTACTCGATGCACTGCACGGCGCCGGAAAAGGCCCCGGAGTTTCTGCGCCACAAGCAGATGCTGCCCCTGCGGTGCAAA
ATGTCAGCAAACCTCAAGCGACATCCGCAAGCGCTAGCGATGATATTACCGATGACGAGTTTGAAGCGCTGCTCGATGAG
CTGCACGGTTCTGGCAAGTTTAAAGGTAAAGTGGAAGAGCCTGCCAAGCCAAAAGTTGAAGCAGTTGTCGCTGCACCAAA
GCCTGCCGCTCCAGCTGTTGATTCGGACGAAATCACTGAAGATGAGTTTGAGCGTCTCCTCGATGAATTACACGGTAAAG
GCGGTGCACCTGCAAAAGTGACTGCGAAAGCCGAATCTGCTCCAGCTAAAACCGAGCCCGCTAAAGCGCCTCCAAGTGCC
GTCGCGCCTTCAACGCCTGCCGCTCCTAAAGCCAGTGTTGCTGCACCAGCAACACCTCCTGCGGTAAAAGCCAAAACTGA
TGTGGCGGTTGCTGAAAAAGCCCCTGCTAAAGCAGCGGCAGCAGCCTCTGCTAACGTACCTCAAGGCGAGACAACTGTTC
GCGTCGATACCGCGAGACTCGACCAAATCATGAACATGGTCGGTGAGTTAGTGTTAGTGCGTAACCGCTTATTGAGTTTA
GGCATTAGTCGTGATGACGAAGAAATGTCTAAGGCGCTAGCGAATTTAGACTTGGTGACAGCAGATTTGCAGGGCGCTGT
GATGAAAACGCGCATGCAACCCATCAAGAAAGTCTTTGGTCGCTTCCCTCGGGTTGTACGCGATTTAGCTCGTACTCTGA
ATAAAGAAATTGATTTAGTCCTCGTGGGCGAAGAGACCGACCTCGATAAAAACTTAGTTGAGGCGCTCGCTGATCCGTTA
GTGCACTTAGTGCGAAACTCGGTAGATCATGGCATTGAGATGCCTAATGACCGTGAGGCCAGCGGCAAACCAAGAACAGG
CACCATCACTCTGTCTGCAAGCCAAGAGGGTGACCATATCCTGCTGAAAATCGAAGACGATGGCGCGGGTATGGATCCTG
AAAAGTTAAAGCAAATTGCCATCAAGCGTGGGGTACTCGATGAGGATACCGCGGCGCGGATGACTGACAGTGAAGCTTAT
AACCTGATTTTTGCGCCTGGCTTCTCGACGAAAGTGGAGATTTCAGATATTTCCGGCCGTGGTGTTGGGATGGACGTGGT
GAAAACCCGTATTACCCAACTTAACGGAACCGTGCATATCGACTCGATGAAAGGCAAAGGCACCATACTTGAGATTAAAG
TGCCGCTGACCTTGGCGATTATGCCGACCTTAATGGTAGACGTTGCCAAGCAGGTGTTTGCATTGCCCTTATCCAGTGTG
AATGAGATTTTCCATCTCGATCTCACCAAGACCAATATTGTCGATGGACAACTCACTGTGATTGTCCGCAACAAGGCCGT
ACCGCTTTTCTATCTGGAGCAGTGGTTACATCGCAATAGAACCAGCTTTAAACATGGTGACAAGAAACACGGCCATGTGG
TGATTGTACAACTGGGGATGATGCAAATTGGTTTTGTTGTTGATGCTTTAATTGGACAAGAAGAAGTGGTGATTAAACCC
TTGGGAGCATTGTTGCATGGCACGCCGGGTATGGCGGGGGCGACAATCACATCCGACGGTGGCATTGCCCTCATCTTGGA
TGTCCCAGGATTATTAAAGCACTATGCGAAAAATAAAAGTTAG

Upstream 100 bases:

>100_bases
ACCGATAATGAATGCCGAGCTTCGTCAAGACGTCGTTACCGGTCAAGATGAAGTCGATGATCTGCTATCGAGTCTGGGTT
TCTAACTGGGAGTCAATTTG

Downstream 100 bases:

>100_bases
TTTCCAATAAGGAATGGAATGGCCATTAAAGTATTAGTCGTTGATGACTCAAGTTTTTTTAGACGACGTGTTAGTGAAAT
AGTCAATCAAGATCCTGAAC

Product: CheA signal transduction histidine kinases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 760; Mature: 759

Protein sequence:

>760_residues
MAFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTNLLNAIFRGFHTVKGGAGFLSLTPMVDVCHEAENTFDLLRTG
KRSVSAELMDIILQAVDAINTMFAQTQQGEQQDPADPALLAKLKMLSSGEPLPSESGQSHAEAESLPEPEPVIETVVEVA
AVEEMPIEKSELSDSSIDEIDEAEFEALLDALHGAGKGPGVSAPQADAAPAVQNVSKPQATSASASDDITDDEFEALLDE
LHGSGKFKGKVEEPAKPKVEAVVAAPKPAAPAVDSDEITEDEFERLLDELHGKGGAPAKVTAKAESAPAKTEPAKAPPSA
VAPSTPAAPKASVAAPATPPAVKAKTDVAVAEKAPAKAAAAASANVPQGETTVRVDTARLDQIMNMVGELVLVRNRLLSL
GISRDDEEMSKALANLDLVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARTLNKEIDLVLVGEETDLDKNLVEALADPL
VHLVRNSVDHGIEMPNDREASGKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKQIAIKRGVLDEDTAARMTDSEAY
NLIFAPGFSTKVEISDISGRGVGMDVVKTRITQLNGTVHIDSMKGKGTILEIKVPLTLAIMPTLMVDVAKQVFALPLSSV
NEIFHLDLTKTNIVDGQLTVIVRNKAVPLFYLEQWLHRNRTSFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKP
LGALLHGTPGMAGATITSDGGIALILDVPGLLKHYAKNKS

Sequences:

>Translated_760_residues
MAFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTNLLNAIFRGFHTVKGGAGFLSLTPMVDVCHEAENTFDLLRTG
KRSVSAELMDIILQAVDAINTMFAQTQQGEQQDPADPALLAKLKMLSSGEPLPSESGQSHAEAESLPEPEPVIETVVEVA
AVEEMPIEKSELSDSSIDEIDEAEFEALLDALHGAGKGPGVSAPQADAAPAVQNVSKPQATSASASDDITDDEFEALLDE
LHGSGKFKGKVEEPAKPKVEAVVAAPKPAAPAVDSDEITEDEFERLLDELHGKGGAPAKVTAKAESAPAKTEPAKAPPSA
VAPSTPAAPKASVAAPATPPAVKAKTDVAVAEKAPAKAAAAASANVPQGETTVRVDTARLDQIMNMVGELVLVRNRLLSL
GISRDDEEMSKALANLDLVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARTLNKEIDLVLVGEETDLDKNLVEALADPL
VHLVRNSVDHGIEMPNDREASGKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKQIAIKRGVLDEDTAARMTDSEAY
NLIFAPGFSTKVEISDISGRGVGMDVVKTRITQLNGTVHIDSMKGKGTILEIKVPLTLAIMPTLMVDVAKQVFALPLSSV
NEIFHLDLTKTNIVDGQLTVIVRNKAVPLFYLEQWLHRNRTSFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKP
LGALLHGTPGMAGATITSDGGIALILDVPGLLKHYAKNKS
>Mature_759_residues
AFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTNLLNAIFRGFHTVKGGAGFLSLTPMVDVCHEAENTFDLLRTGK
RSVSAELMDIILQAVDAINTMFAQTQQGEQQDPADPALLAKLKMLSSGEPLPSESGQSHAEAESLPEPEPVIETVVEVAA
VEEMPIEKSELSDSSIDEIDEAEFEALLDALHGAGKGPGVSAPQADAAPAVQNVSKPQATSASASDDITDDEFEALLDEL
HGSGKFKGKVEEPAKPKVEAVVAAPKPAAPAVDSDEITEDEFERLLDELHGKGGAPAKVTAKAESAPAKTEPAKAPPSAV
APSTPAAPKASVAAPATPPAVKAKTDVAVAEKAPAKAAAAASANVPQGETTVRVDTARLDQIMNMVGELVLVRNRLLSLG
ISRDDEEMSKALANLDLVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARTLNKEIDLVLVGEETDLDKNLVEALADPLV
HLVRNSVDHGIEMPNDREASGKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKQIAIKRGVLDEDTAARMTDSEAYN
LIFAPGFSTKVEISDISGRGVGMDVVKTRITQLNGTVHIDSMKGKGTILEIKVPLTLAIMPTLMVDVAKQVFALPLSSVN
EIFHLDLTKTNIVDGQLTVIVRNKAVPLFYLEQWLHRNRTSFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKPL
GALLHGTPGMAGATITSDGGIALILDVPGLLKHYAKNKS

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=421, Percent_Identity=41.0926365795724, Blast_Score=295, Evalue=6e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80963; Mature: 80832

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTNLLNAIFRGFHTVKGGAGFLSL
CCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEH
TPMVDVCHEAENTFDLLRTGKRSVSAELMDIILQAVDAINTMFAQTQQGEQQDPADPALL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
AKLKMLSSGEPLPSESGQSHAEAESLPEPEPVIETVVEVAAVEEMPIEKSELSDSSIDEI
HHHHHHCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHH
DEAEFEALLDALHGAGKGPGVSAPQADAAPAVQNVSKPQATSASASDDITDDEFEALLDE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
LHGSGKFKGKVEEPAKPKVEAVVAAPKPAAPAVDSDEITEDEFERLLDELHGKGGAPAKV
HCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEE
TAKAESAPAKTEPAKAPPSAVAPSTPAAPKASVAAPATPPAVKAKTDVAVAEKAPAKAAA
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHH
AASANVPQGETTVRVDTARLDQIMNMVGELVLVRNRLLSLGISRDDEEMSKALANLDLVT
HHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEE
ADLQGAVMKTRMQPIKKVFGRFPRVVRDLARTLNKEIDLVLVGEETDLDKNLVEALADPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHH
VHLVRNSVDHGIEMPNDREASGKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKQIA
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHH
IKRGVLDEDTAARMTDSEAYNLIFAPGFSTKVEISDISGRGVGMDVVKTRITQLNGTVHI
HHCCCCCCCHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEE
DSMKGKGTILEIKVPLTLAIMPTLMVDVAKQVFALPLSSVNEIFHLDLTKTNIVDGQLTV
ECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEECCCCEEECCEEEE
IVRNKAVPLFYLEQWLHRNRTSFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKP
EEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHH
LGALLHGTPGMAGATITSDGGIALILDVPGLLKHYAKNKS
HHHHHCCCCCCCCCEEECCCCEEEEECCCHHHHHHHCCCC
>Mature Secondary Structure 
AFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTNLLNAIFRGFHTVKGGAGFLSL
CCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEH
TPMVDVCHEAENTFDLLRTGKRSVSAELMDIILQAVDAINTMFAQTQQGEQQDPADPALL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
AKLKMLSSGEPLPSESGQSHAEAESLPEPEPVIETVVEVAAVEEMPIEKSELSDSSIDEI
HHHHHHCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHH
DEAEFEALLDALHGAGKGPGVSAPQADAAPAVQNVSKPQATSASASDDITDDEFEALLDE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
LHGSGKFKGKVEEPAKPKVEAVVAAPKPAAPAVDSDEITEDEFERLLDELHGKGGAPAKV
HCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEE
TAKAESAPAKTEPAKAPPSAVAPSTPAAPKASVAAPATPPAVKAKTDVAVAEKAPAKAAA
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHH
AASANVPQGETTVRVDTARLDQIMNMVGELVLVRNRLLSLGISRDDEEMSKALANLDLVT
HHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEE
ADLQGAVMKTRMQPIKKVFGRFPRVVRDLARTLNKEIDLVLVGEETDLDKNLVEALADPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHH
VHLVRNSVDHGIEMPNDREASGKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKQIA
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHH
IKRGVLDEDTAARMTDSEAYNLIFAPGFSTKVEISDISGRGVGMDVVKTRITQLNGTVHI
HHCCCCCCCHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEE
DSMKGKGTILEIKVPLTLAIMPTLMVDVAKQVFALPLSSVNEIFHLDLTKTNIVDGQLTV
ECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEECCCCEEECCEEEE
IVRNKAVPLFYLEQWLHRNRTSFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKP
EEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHH
LGALLHGTPGMAGATITSDGGIALILDVPGLLKHYAKNKS
HHHHHCCCCCCCCCEEECCCCEEEEECCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]