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The map label for this gene is tadA [H]

Identifier: 113969580

GI number: 113969580

Start: 1438690

End: 1439448

Strand: Direct

Name: tadA [H]

Synonym: Shewmr4_1236

Alternate gene names: 113969580

Gene position: 1438690-1439448 (Clockwise)

Preceding gene: 113969579

Following gene: 113969582

Centisome position: 30.57

GC content: 50.72

Gene sequence:

>759_bases
GTGGAGCAGACAAAACTGAACCCAAAAACCTTGCATGCGAAGACGCTCAGCTCTGATGAACTTGGCGCTGATGAACTTGG
CGCTGATGAACTTGGCTCTGTTGAACTTGGCTCTGTTGAACTTGGCTCTGTTGAACTTGGCTCTGTTGAACTTGGCGCTG
ATGAACTTGGTTGTGATGAAGCTAGTGGTAATGTGTTAATTGGCGAGCAACCTTGTCTCAATCAAGCGAGTCTCAATCAA
GTGGATGTTGAACAACCTCGAGTCGATGAACATTGGATGCGTGTCGCAATGGCCATGGCTGAAAAGGCTGAGGCTGCGGG
TGAAGTACCTGTGGGGGCGGTTTTAGTCAAAGAGGGTCAGCAAATCGCCACTGGATACAACTTGTCTATCAGTGAGCACG
ACCCGTGCGCCCATGCTGAAATTCAGTGTTTGCGAGCAGCGGGACAGACGATTGAAAACTATCGACTCCTCGATACCACT
CTTTACGTTACCCTCGAGCCTTGTGCAATGTGCGCCGGTGCTATGGTGCATAGCCGGATTGCCCGCGTGGTATTTGGGGC
AAAGGATGAGAAGACGGGCGCTGCAGGAACCGTGCTTAACCTCTTGCAGCATCCAGCCTTTAATCATCAAGTTGAGATTA
CATCTGGGGTGTTAGCGCAGGACTGTGCTGACCAATTGAGCCGCTTTTTTAAACGTCGCAGGGAGGAAAAGAAGGCTTTA
AAACAGGCTCAAAAGGCGCAGCAGGGGACGCTATCCTAA

Upstream 100 bases:

>100_bases
GTTTTGATGACATGATGCATTAACGAAAAGGCGCCAAGTGCGCCTTTTTTGTTGGTTATGGGTATAATTGCCCACATTGT
TGATAAAAGAGAATCCTTAA

Downstream 100 bases:

>100_bases
GGAGTTTGGGGACTCGCTTAAGCGTTAGTCTTGGGCTTGGAGAAACGTAAAAAACAGTTTGTGGCGATTCAGCACCCGGC
GATGGCGAATTTTCAATGTG

Product: CMP/dCMP deaminase, zinc-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MEQTKLNPKTLHAKTLSSDELGADELGADELGSVELGSVELGSVELGSVELGADELGCDEASGNVLIGEQPCLNQASLNQ
VDVEQPRVDEHWMRVAMAMAEKAEAAGEVPVGAVLVKEGQQIATGYNLSISEHDPCAHAEIQCLRAAGQTIENYRLLDTT
LYVTLEPCAMCAGAMVHSRIARVVFGAKDEKTGAAGTVLNLLQHPAFNHQVEITSGVLAQDCADQLSRFFKRRREEKKAL
KQAQKAQQGTLS

Sequences:

>Translated_252_residues
MEQTKLNPKTLHAKTLSSDELGADELGADELGSVELGSVELGSVELGSVELGADELGCDEASGNVLIGEQPCLNQASLNQ
VDVEQPRVDEHWMRVAMAMAEKAEAAGEVPVGAVLVKEGQQIATGYNLSISEHDPCAHAEIQCLRAAGQTIENYRLLDTT
LYVTLEPCAMCAGAMVHSRIARVVFGAKDEKTGAAGTVLNLLQHPAFNHQVEITSGVLAQDCADQLSRFFKRRREEKKAL
KQAQKAQQGTLS
>Mature_252_residues
MEQTKLNPKTLHAKTLSSDELGADELGADELGSVELGSVELGSVELGSVELGADELGCDEASGNVLIGEQPCLNQASLNQ
VDVEQPRVDEHWMRVAMAMAEKAEAAGEVPVGAVLVKEGQQIATGYNLSISEHDPCAHAEIQCLRAAGQTIENYRLLDTT
LYVTLEPCAMCAGAMVHSRIARVVFGAKDEKTGAAGTVLNLLQHPAFNHQVEITSGVLAQDCADQLSRFFKRRREEKKAL
KQAQKAQQGTLS

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=152, Percent_Identity=32.2368421052632, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI145693172, Length=157, Percent_Identity=59.8726114649682, Blast_Score=205, Evalue=2e-54,
Organism=Escherichia coli, GI1786616, Length=155, Percent_Identity=31.6129032258064, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17554608, Length=119, Percent_Identity=33.6134453781513, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17541138, Length=148, Percent_Identity=31.0810810810811, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322425, Length=160, Percent_Identity=33.75, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=31.5068493150685, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 27009; Mature: 27009

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTKLNPKTLHAKTLSSDELGADELGADELGSVELGSVELGSVELGSVELGADELGCDE
CCCCCCCCHHEEECCCCCCCCCCHHCCCCCCCCEEECCEEECCEEECCEEECCHHCCCCC
ASGNVLIGEQPCLNQASLNQVDVEQPRVDEHWMRVAMAMAEKAEAAGEVPVGAVLVKEGQ
CCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
QIATGYNLSISEHDPCAHAEIQCLRAAGQTIENYRLLDTTLYVTLEPCAMCAGAMVHSRI
EEECCEEEEECCCCCCHHHHHHHHHHHHHHHHCEEEEEEEEEEEECHHHHHHHHHHHHHH
ARVVFGAKDEKTGAAGTVLNLLQHPAFNHQVEITSGVLAQDCADQLSRFFKRRREEKKAL
HHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHH
KQAQKAQQGTLS
HHHHHHHCCCCC
>Mature Secondary Structure
MEQTKLNPKTLHAKTLSSDELGADELGADELGSVELGSVELGSVELGSVELGADELGCDE
CCCCCCCCHHEEECCCCCCCCCCHHCCCCCCCCEEECCEEECCEEECCEEECCHHCCCCC
ASGNVLIGEQPCLNQASLNQVDVEQPRVDEHWMRVAMAMAEKAEAAGEVPVGAVLVKEGQ
CCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
QIATGYNLSISEHDPCAHAEIQCLRAAGQTIENYRLLDTTLYVTLEPCAMCAGAMVHSRI
EEECCEEEEECCCCCCHHHHHHHHHHHHHHHHCEEEEEEEEEEEECHHHHHHHHHHHHHH
ARVVFGAKDEKTGAAGTVLNLLQHPAFNHQVEITSGVLAQDCADQLSRFFKRRREEKKAL
HHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHH
KQAQKAQQGTLS
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]