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The map label for this gene is cfa [H]

Identifier: 113969514

GI number: 113969514

Start: 1376457

End: 1377713

Strand: Direct

Name: cfa [H]

Synonym: Shewmr4_1170

Alternate gene names: 113969514

Gene position: 1376457-1377713 (Clockwise)

Preceding gene: 113969513

Following gene: 113969515

Centisome position: 29.25

GC content: 49.8

Gene sequence:

>1257_bases
ATGGAAAACACTGCATCGCAATCTTCTGTTATTACGGCAAAATTGCCTGACAGTCTGGCCCGTAAGCTACTGCTTAAAGC
ATTAGAAAATCTCCCCCACGGCTGTTTAACCTTAGTGGAGGGCGACAAGAGCTATCGCTTTGGTGAGCATCACAGTGATT
TGCATGCCACCCTGGTGGTGAAGCATCCTAGCTTCTATCGCCAAGCGATGTTTTCGGGCTCCATTGGCGCCGGTGAAAGC
TATATCCAAGGTCATTGGACTAGCCCAGATCTCACTAAGGTGGTGCAACTGTTTGCCCGCAATCTGCCCTTGCTCGATAA
GATTGAGGCGAAATTTGGTTGGCTGACAGGATCGGTTAACCGTATGAAACATATGCTGAATCGTAACTCACAGCAGGGCT
CTAAACGTAATATCTTGGCCCATTACGACTTAGGTAATGCCTTGTATGAGCAGTTTTTAGATCGCGAAATGTTGTACTCC
AGCGCTCTTTATCCCGATAGCGGAGCGAGTCTGGAACAAGCGCAGCTGCATAAACTGAAAACCATTTGTGAGCGGCTCGA
CCTACAACCTGGGCAGACCTTACTCGAAATCGGAACGGGGTGGGGCGCCTTAGCCATTTACGCAGCTAAACATTATGGCG
TGCACGTGACGACCACAACGATTTCGGATGCGCAATATGCTTACGCGAAAGCGCGAGTCGAACGGGAAGGCTTAAGCGAT
AGCATCACCTTATTGACTGAGGATTACCGTAATCTCGGTGGCACTTACGACAGACTAGTGTCTATCGAGATGATAGAAGC
CGTTGGCCATGAGTACCTGCCGGGGTTCTTTAAAAAGCTCGAATCCCTACTCAAACCCCATGGCCGCATGTTATTGCAGG
CTATCACCATCGCCGACCAACGTTACGACAGTTATCGCAAAGGTGTTGATTTTATTCAGCGATATATTTTCCCTGGCGGT
TGCTTACCTTCGGTGCACCAAATGGTTGGACACTTGGCCAAGCGCACCGATATGCAGGTGTGGTCGATTGATGATATGGG
CCTCGATTATGCCAAGACTTTAAGGGACTGGCATAACAACTTCGACCGCGCCATCGAGCAAGTGCAAGCCCTTGGCTATG
GCGACGACTTTATCCGCATGTGGAAGTTTTACTTAAGTTATTGCGAAGGAGGCTTTTTAGAGCGCACCACGAGCACAGTG
CATTTGGTTGCGGTGCGCCCAGACTACCGTTTGCCGAATGCGGTGAGCGGCAACTAA

Upstream 100 bases:

>100_bases
ATGACGCTGAAAATTTTCGGCGGAATTTATTGGCAGGCGTTAAAGCTGTTCTTTAAGCGCGTACCTTTTGTGCCACATCC
TGCCCAAGTGGAGAAATAAA

Downstream 100 bases:

>100_bases
GGTGGTGATGAGATGTCCTCTATGGCGAGAAATATACTCAATATCTCAAAGTATCAGGGCTTTATACTCTATAACGCCTT
GAGTTTTCAATGTGTGTGGT

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MENTASQSSVITAKLPDSLARKLLLKALENLPHGCLTLVEGDKSYRFGEHHSDLHATLVVKHPSFYRQAMFSGSIGAGES
YIQGHWTSPDLTKVVQLFARNLPLLDKIEAKFGWLTGSVNRMKHMLNRNSQQGSKRNILAHYDLGNALYEQFLDREMLYS
SALYPDSGASLEQAQLHKLKTICERLDLQPGQTLLEIGTGWGALAIYAAKHYGVHVTTTTISDAQYAYAKARVEREGLSD
SITLLTEDYRNLGGTYDRLVSIEMIEAVGHEYLPGFFKKLESLLKPHGRMLLQAITIADQRYDSYRKGVDFIQRYIFPGG
CLPSVHQMVGHLAKRTDMQVWSIDDMGLDYAKTLRDWHNNFDRAIEQVQALGYGDDFIRMWKFYLSYCEGGFLERTTSTV
HLVAVRPDYRLPNAVSGN

Sequences:

>Translated_418_residues
MENTASQSSVITAKLPDSLARKLLLKALENLPHGCLTLVEGDKSYRFGEHHSDLHATLVVKHPSFYRQAMFSGSIGAGES
YIQGHWTSPDLTKVVQLFARNLPLLDKIEAKFGWLTGSVNRMKHMLNRNSQQGSKRNILAHYDLGNALYEQFLDREMLYS
SALYPDSGASLEQAQLHKLKTICERLDLQPGQTLLEIGTGWGALAIYAAKHYGVHVTTTTISDAQYAYAKARVEREGLSD
SITLLTEDYRNLGGTYDRLVSIEMIEAVGHEYLPGFFKKLESLLKPHGRMLLQAITIADQRYDSYRKGVDFIQRYIFPGG
CLPSVHQMVGHLAKRTDMQVWSIDDMGLDYAKTLRDWHNNFDRAIEQVQALGYGDDFIRMWKFYLSYCEGGFLERTTSTV
HLVAVRPDYRLPNAVSGN
>Mature_418_residues
MENTASQSSVITAKLPDSLARKLLLKALENLPHGCLTLVEGDKSYRFGEHHSDLHATLVVKHPSFYRQAMFSGSIGAGES
YIQGHWTSPDLTKVVQLFARNLPLLDKIEAKFGWLTGSVNRMKHMLNRNSQQGSKRNILAHYDLGNALYEQFLDREMLYS
SALYPDSGASLEQAQLHKLKTICERLDLQPGQTLLEIGTGWGALAIYAAKHYGVHVTTTTISDAQYAYAKARVEREGLSD
SITLLTEDYRNLGGTYDRLVSIEMIEAVGHEYLPGFFKKLESLLKPHGRMLLQAITIADQRYDSYRKGVDFIQRYIFPGG
CLPSVHQMVGHLAKRTDMQVWSIDDMGLDYAKTLRDWHNNFDRAIEQVQALGYGDDFIRMWKFYLSYCEGGFLERTTSTV
HLVAVRPDYRLPNAVSGN

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=364, Percent_Identity=36.5384615384615, Blast_Score=197, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI133904226, Length=366, Percent_Identity=36.0655737704918, Blast_Score=206, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 47235; Mature: 47235

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTASQSSVITAKLPDSLARKLLLKALENLPHGCLTLVEGDKSYRFGEHHSDLHATLVV
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEEE
KHPSFYRQAMFSGSIGAGESYIQGHWTSPDLTKVVQLFARNLPLLDKIEAKFGWLTGSVN
ECCHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHH
RMKHMLNRNSQQGSKRNILAHYDLGNALYEQFLDREMLYSSALYPDSGASLEQAQLHKLK
HHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
TICERLDLQPGQTLLEIGTGWGALAIYAAKHYGVHVTTTTISDAQYAYAKARVEREGLSD
HHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHCCEEEEEEEECCHHHHHHHHHHHHCCCCC
SITLLTEDYRNLGGTYDRLVSIEMIEAVGHEYLPGFFKKLESLLKPHGRMLLQAITIADQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHCHHHHHHHHHHHCHHHHHHHHHHHHHHH
RYDSYRKGVDFIQRYIFPGGCLPSVHQMVGHLAKRTDMQVWSIDDMGLDYAKTLRDWHNN
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHH
FDRAIEQVQALGYGDDFIRMWKFYLSYCEGGFLERTTSTVHLVAVRPDYRLPNAVSGN
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCCEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MENTASQSSVITAKLPDSLARKLLLKALENLPHGCLTLVEGDKSYRFGEHHSDLHATLVV
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEEE
KHPSFYRQAMFSGSIGAGESYIQGHWTSPDLTKVVQLFARNLPLLDKIEAKFGWLTGSVN
ECCHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHH
RMKHMLNRNSQQGSKRNILAHYDLGNALYEQFLDREMLYSSALYPDSGASLEQAQLHKLK
HHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
TICERLDLQPGQTLLEIGTGWGALAIYAAKHYGVHVTTTTISDAQYAYAKARVEREGLSD
HHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHCCEEEEEEEECCHHHHHHHHHHHHCCCCC
SITLLTEDYRNLGGTYDRLVSIEMIEAVGHEYLPGFFKKLESLLKPHGRMLLQAITIADQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHCHHHHHHHHHHHCHHHHHHHHHHHHHHH
RYDSYRKGVDFIQRYIFPGGCLPSVHQMVGHLAKRTDMQVWSIDDMGLDYAKTLRDWHNN
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHH
FDRAIEQVQALGYGDDFIRMWKFYLSYCEGGFLERTTSTVHLVAVRPDYRLPNAVSGN
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCCEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]