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The map label for this gene is aer [H]

Identifier: 113969493

GI number: 113969493

Start: 1351448

End: 1353016

Strand: Direct

Name: aer [H]

Synonym: Shewmr4_1149

Alternate gene names: 113969493

Gene position: 1351448-1353016 (Clockwise)

Preceding gene: 113969487

Following gene: 113969494

Centisome position: 28.72

GC content: 50.41

Gene sequence:

>1569_bases
ATGCAAACACATTCAAAAAATGGTGAAAAACACCTATCCGAAAACGCTATTCTCCTCTCGACAACCGATCTGAAAGGCAA
CATTAAGTATGTCAATCAAACCTTTTCGCAGATCAGTGAATATAGCGTTGCCGAGTTGCAGGGGAGCCCGCATAACATAG
TGCGCCATGGTGATATGCCATCAGCCGCCTTTAAAATGCTTTGGGAACGGATAAGAAGCGGCAAACCTTGGATGGGGATT
GTCAAAAATAGAACAAAAACCGGTGGCTATTACTGGGTGAATGCCTACGTCGCCCCTGTGTACGAAAATGGCAAAATTCA
TGAGTATCAATCCGTTCGCCGCCAAGCAACCCCAGAACAAATCAAGGCGGCCGAGGAAATCTATCAAGGGATCAATCAAG
GACAACAGCCCAAGGCGCTGAAAAAAGACCGCTTAGGATTTCGCGGAAAAATACTCGTGACGATGTTGTTTACCATCGCA
CTAACTGCCTACTTGGCAACGTATTCGCCCATCTTAGCTGCCCTTGCTGGTGGACTACTTGCTTTGGGTCTGTGGTATAT
GCTCATGCAGCCTTTTCAGGCATTAGTACAGGTGGCCAGCAATATTATCGATGATCCCGTTGCTATGGGGGTTTACACCG
GCAGGCAAGATGAAATCGGTAAGCTAGATCTGGCGCTGCGATTTTTGATCACCGAAATTGGCGGCGTAGTGGGCCGAATG
GCGGATTCTGCCAGTGAGATCCAAGAGCAGAGCGTGAATCTGAAACAAACTATCACCAATACTTGGGAACATGCCGATAG
CCAGAGCGCGCAAACCACACAGGCTGCAACGGCGATGGAGCAAATGAGTGCCAGCTTTGCGGAGGTAACGGATAATATCC
ATCGCACCGCATCCGAGATGGTTTCTAGCCATGAGGCGGCGCAGCGTGGTCATTCACGGCTTGAAACCGTTATCGAGGCG
ATACATCAGCTGAGTGTACAGGTGAGCCATTTCTCCGATGTGGTGCAAACGATTGAGCAGGACAGCCAAGCGATTCATCA
AGTGCTAGAAGTGATCCGCGCGATTGCCGATCAAACCAATCTGTTAGCGCTGAATGCCGCGATTGAAGCGGCGCGGGCGG
GGGAAAGCGGTCGCGGTTTTGCGGTCGTTGCCGATGAAGTCCGGCAGTTATCTAGCCGAACCAGCCAGTCGACCTCGCAA
ATTGAACAGATTGTAAGCCGCTTTAAAGACAGTACGCAAAGGGCGGTATCAACTATGACGGCGGGTCAAGAGCAGGTTAA
GCGCTCAGTTTCATTAGCGCAGGATGCCAGCATTGCCTTTGGTGAGTTGTTATCTTCTATCGCTAGAATTAACTCTTTGA
GTGATGATAATGCGGCCGCAATGACTCAGCAGACCTCCGTGGCGGCAGAAATCAGCCGTGCTATCCATGTGATCAGCGAT
TTGGCGCAGCAGAGTTTGCAGCAGACCCAGGATGCGGCGGCCAGGGGAGATCAGGTTTCGCGATTATCGACTAAAACCCA
CCACCTATCGCAGCAATTCTGGCAACAGAGCGTACAACGTAAGTATTAA

Upstream 100 bases:

>100_bases
TTAATTTTTATGCTCTCACTGTGAGCTTAATCAAAGCAGGCGTTCTGTGCTTTTGGCAAAATGCGGCGCAACTTTCACAT
GGAATCCGTTAGTGCGCCCT

Downstream 100 bases:

>100_bases
TCCTTGGTATTCAACTGGTTGGTTTATATTTTTTGTCGATTATAAATCAACCAGTTACTCATTTTTTTAGTTCCCTTATC
GTGTCATTTCTTTGATAAAT

Product: methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MQTHSKNGEKHLSENAILLSTTDLKGNIKYVNQTFSQISEYSVAELQGSPHNIVRHGDMPSAAFKMLWERIRSGKPWMGI
VKNRTKTGGYYWVNAYVAPVYENGKIHEYQSVRRQATPEQIKAAEEIYQGINQGQQPKALKKDRLGFRGKILVTMLFTIA
LTAYLATYSPILAALAGGLLALGLWYMLMQPFQALVQVASNIIDDPVAMGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
ADSASEIQEQSVNLKQTITNTWEHADSQSAQTTQAATAMEQMSASFAEVTDNIHRTASEMVSSHEAAQRGHSRLETVIEA
IHQLSVQVSHFSDVVQTIEQDSQAIHQVLEVIRAIADQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSQSTSQ
IEQIVSRFKDSTQRAVSTMTAGQEQVKRSVSLAQDASIAFGELLSSIARINSLSDDNAAAMTQQTSVAAEISRAIHVISD
LAQQSLQQTQDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY

Sequences:

>Translated_522_residues
MQTHSKNGEKHLSENAILLSTTDLKGNIKYVNQTFSQISEYSVAELQGSPHNIVRHGDMPSAAFKMLWERIRSGKPWMGI
VKNRTKTGGYYWVNAYVAPVYENGKIHEYQSVRRQATPEQIKAAEEIYQGINQGQQPKALKKDRLGFRGKILVTMLFTIA
LTAYLATYSPILAALAGGLLALGLWYMLMQPFQALVQVASNIIDDPVAMGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
ADSASEIQEQSVNLKQTITNTWEHADSQSAQTTQAATAMEQMSASFAEVTDNIHRTASEMVSSHEAAQRGHSRLETVIEA
IHQLSVQVSHFSDVVQTIEQDSQAIHQVLEVIRAIADQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSQSTSQ
IEQIVSRFKDSTQRAVSTMTAGQEQVKRSVSLAQDASIAFGELLSSIARINSLSDDNAAAMTQQTSVAAEISRAIHVISD
LAQQSLQQTQDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY
>Mature_522_residues
MQTHSKNGEKHLSENAILLSTTDLKGNIKYVNQTFSQISEYSVAELQGSPHNIVRHGDMPSAAFKMLWERIRSGKPWMGI
VKNRTKTGGYYWVNAYVAPVYENGKIHEYQSVRRQATPEQIKAAEEIYQGINQGQQPKALKKDRLGFRGKILVTMLFTIA
LTAYLATYSPILAALAGGLLALGLWYMLMQPFQALVQVASNIIDDPVAMGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
ADSASEIQEQSVNLKQTITNTWEHADSQSAQTTQAATAMEQMSASFAEVTDNIHRTASEMVSSHEAAQRGHSRLETVIEA
IHQLSVQVSHFSDVVQTIEQDSQAIHQVLEVIRAIADQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSQSTSQ
IEQIVSRFKDSTQRAVSTMTAGQEQVKRSVSLAQDASIAFGELLSSIARINSLSDDNAAAMTQQTSVAAEISRAIHVISD
LAQQSLQQTQDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=503, Percent_Identity=31.8091451292247, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1788194, Length=340, Percent_Identity=30.8823529411765, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI2367378, Length=339, Percent_Identity=26.8436578171091, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787690, Length=404, Percent_Identity=28.4653465346535, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788195, Length=305, Percent_Identity=25.9016393442623, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 57374; Mature: 57374

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTHSKNGEKHLSENAILLSTTDLKGNIKYVNQTFSQISEYSVAELQGSPHNIVRHGDMP
CCCCCCCCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCC
SAAFKMLWERIRSGKPWMGIVKNRTKTGGYYWVNAYVAPVYENGKIHEYQSVRRQATPEQ
HHHHHHHHHHHHCCCCCCHHHCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHCCHHH
IKAAEEIYQGINQGQQPKALKKDRLGFRGKILVTMLFTIALTAYLATYSPILAALAGGLL
HHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGLWYMLMQPFQALVQVASNIIDDPVAMGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
ADSASEIQEQSVNLKQTITNTWEHADSQSAQTTQAATAMEQMSASFAEVTDNIHRTASEM
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSSHEAAQRGHSRLETVIEAIHQLSVQVSHFSDVVQTIEQDSQAIHQVLEVIRAIADQTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSQSTSQIEQIVSRFKDSTQRAVSTMT
EEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
AGQEQVKRSVSLAQDASIAFGELLSSIARINSLSDDNAAAMTQQTSVAAEISRAIHVISD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LAQQSLQQTQDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQTHSKNGEKHLSENAILLSTTDLKGNIKYVNQTFSQISEYSVAELQGSPHNIVRHGDMP
CCCCCCCCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCC
SAAFKMLWERIRSGKPWMGIVKNRTKTGGYYWVNAYVAPVYENGKIHEYQSVRRQATPEQ
HHHHHHHHHHHHCCCCCCHHHCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHCCHHH
IKAAEEIYQGINQGQQPKALKKDRLGFRGKILVTMLFTIALTAYLATYSPILAALAGGLL
HHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGLWYMLMQPFQALVQVASNIIDDPVAMGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
ADSASEIQEQSVNLKQTITNTWEHADSQSAQTTQAATAMEQMSASFAEVTDNIHRTASEM
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSSHEAAQRGHSRLETVIEAIHQLSVQVSHFSDVVQTIEQDSQAIHQVLEVIRAIADQTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSQSTSQIEQIVSRFKDSTQRAVSTMT
EEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
AGQEQVKRSVSLAQDASIAFGELLSSIARINSLSDDNAAAMTQQTSVAAEISRAIHVISD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LAQQSLQQTQDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]