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The map label for this gene is nlpI [H]

Identifier: 113969376

GI number: 113969376

Start: 1203739

End: 1204641

Strand: Direct

Name: nlpI [H]

Synonym: Shewmr4_1032

Alternate gene names: 113969376

Gene position: 1203739-1204641 (Clockwise)

Preceding gene: 113969375

Following gene: 113969377

Centisome position: 25.58

GC content: 46.29

Gene sequence:

>903_bases
ATGAGTCTTAAAATTAGAACCGCTGTTGTTGCTGTGCTGGCGGGTGCCAGTTTGATGTTGGCTGGATGTGCGACCACTAA
GTCTCCCTTAGACAACCAAAATGACGTTGAAGGCAAGTTAGTCATCGCCCCTGTGATGCCTGACTATAAAGTTGAAGTCA
CCCTTGCCAAGCTGAACGAAATTTTATCGGCGGTTGAACTAACAAACGAGCAGCGCGCACGTTTTCATTACGATCGTGGC
GTGATTTACGACAGCGTTGGTTTACGCTTAATGGCGCGCATCGATTTTATGCAGGCGCTTAAACTGCAACCCGACTTAGC
CGATGCCTATAACTTCCTTGGTATTTATTACACCCAAGAAGGTGAATACGATAGTGCCTATGAGGCGTTTGATGGTGTAT
TAGAGCTGTCGCCAAACTATGACTATGCCTACTTGAATCGCGGCATTGCGCTTTATTATGGCGATCGGAACGATCTCGCC
TTAAAAGATATGCAAGCATTTTACGCTGGCGATAATAAAGATGGTTATCGCGCACTGTGGTTATATCTCATTCAGTCAAA
GGATAACGCCGAAGAAGCTAAACGTCAGTTACAGGAACACCGTAAGGGACTGGAAGCCGATGCCTGGTCAACCGTGATTG
TTGATTATTACCTCGGTGCTAAGAGCCGCGAGCAGGTTTTTGCCGACGCCAAGTTAGGCCTGACTCACCCTAAAGAATAT
GCTGAGCGTCTCTGTGAAGCGTATTTCTACCTCGCGAAAATCGAAATTGCCAAGAATCAATACCAAGAGGCAGCGAATTA
TTTCCGTCTTGCCCTCGCGACCAATATCTATGACTTTGTTGAGCACAGATACGCGCGAATTGAGCTAGCTAAAGTTAAAG
GTTTGCTCGAAGGCACAAAATAA

Upstream 100 bases:

>100_bases
AAATTGCGTTTAATGCTATTCCTCAATAGCAGTCCTGAAGTGGGATTGCTATCATGAATGTTCTTCTGCGTGGGTTGGGA
ATCTAAAAAGGTAGAAATGG

Downstream 100 bases:

>100_bases
GCCATATCGCCCGAGGTACATCTCGGGCTTTACCTAGCCAAGTACGCACTGAGGCGCTATAATTTGCGCCTTTTTTAGCG
ATACGAGTGCATAGGTTAAA

Product: lipoprotein NlpI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSLKIRTAVVAVLAGASLMLAGCATTKSPLDNQNDVEGKLVIAPVMPDYKVEVTLAKLNEILSAVELTNEQRARFHYDRG
VIYDSVGLRLMARIDFMQALKLQPDLADAYNFLGIYYTQEGEYDSAYEAFDGVLELSPNYDYAYLNRGIALYYGDRNDLA
LKDMQAFYAGDNKDGYRALWLYLIQSKDNAEEAKRQLQEHRKGLEADAWSTVIVDYYLGAKSREQVFADAKLGLTHPKEY
AERLCEAYFYLAKIEIAKNQYQEAANYFRLALATNIYDFVEHRYARIELAKVKGLLEGTK

Sequences:

>Translated_300_residues
MSLKIRTAVVAVLAGASLMLAGCATTKSPLDNQNDVEGKLVIAPVMPDYKVEVTLAKLNEILSAVELTNEQRARFHYDRG
VIYDSVGLRLMARIDFMQALKLQPDLADAYNFLGIYYTQEGEYDSAYEAFDGVLELSPNYDYAYLNRGIALYYGDRNDLA
LKDMQAFYAGDNKDGYRALWLYLIQSKDNAEEAKRQLQEHRKGLEADAWSTVIVDYYLGAKSREQVFADAKLGLTHPKEY
AERLCEAYFYLAKIEIAKNQYQEAANYFRLALATNIYDFVEHRYARIELAKVKGLLEGTK
>Mature_299_residues
SLKIRTAVVAVLAGASLMLAGCATTKSPLDNQNDVEGKLVIAPVMPDYKVEVTLAKLNEILSAVELTNEQRARFHYDRGV
IYDSVGLRLMARIDFMQALKLQPDLADAYNFLGIYYTQEGEYDSAYEAFDGVLELSPNYDYAYLNRGIALYYGDRNDLAL
KDMQAFYAGDNKDGYRALWLYLIQSKDNAEEAKRQLQEHRKGLEADAWSTVIVDYYLGAKSREQVFADAKLGLTHPKEYA
ERLCEAYFYLAKIEIAKNQYQEAANYFRLALATNIYDFVEHRYARIELAKVKGLLEGTK

Specific function: May be involved in cell division. Overexpression of nlpI results in the loss of the rod morphology and the formation of single prolate ellipsoids and pairs of prolate ellipsoids joined by partial constrictions [H]

COG id: COG4785

COG function: function code R; Lipoprotein NlpI, contains TPR repeats

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1789554, Length=279, Percent_Identity=43.7275985663082, Blast_Score=242, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 34099; Mature: 33968

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKIRTAVVAVLAGASLMLAGCATTKSPLDNQNDVEGKLVIAPVMPDYKVEVTLAKLNE
CCEEHHHHHHHHHHCCHHEEEECCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEHHHHHH
ILSAVELTNEQRARFHYDRGVIYDSVGLRLMARIDFMQALKLQPDLADAYNFLGIYYTQE
HHHHHHHCCCHHHHEEECCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHCEEEEEEECC
GEYDSAYEAFDGVLELSPNYDYAYLNRGIALYYGDRNDLALKDMQAFYAGDNKDGYRALW
CCCCHHHHHHCCEEEECCCCCCHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEE
LYLIQSKDNAEEAKRQLQEHRKGLEADAWSTVIVDYYLGAKSREQVFADAKLGLTHPKEY
EEEEECCCCHHHHHHHHHHHHCCCCCCCHHHEEEHHHCCCCCHHHHHHHCCCCCCCCHHH
AERLCEAYFYLAKIEIAKNQYQEAANYFRLALATNIYDFVEHRYARIELAKVKGLLEGTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLKIRTAVVAVLAGASLMLAGCATTKSPLDNQNDVEGKLVIAPVMPDYKVEVTLAKLNE
CEEHHHHHHHHHHCCHHEEEECCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEHHHHHH
ILSAVELTNEQRARFHYDRGVIYDSVGLRLMARIDFMQALKLQPDLADAYNFLGIYYTQE
HHHHHHHCCCHHHHEEECCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHCEEEEEEECC
GEYDSAYEAFDGVLELSPNYDYAYLNRGIALYYGDRNDLALKDMQAFYAGDNKDGYRALW
CCCCHHHHHHCCEEEECCCCCCHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEE
LYLIQSKDNAEEAKRQLQEHRKGLEADAWSTVIVDYYLGAKSREQVFADAKLGLTHPKEY
EEEEECCCCHHHHHHHHHHHHCCCCCCCHHHEEEHHHCCCCCHHHHHHHCCCCCCCCHHH
AERLCEAYFYLAKIEIAKNQYQEAANYFRLALATNIYDFVEHRYARIELAKVKGLLEGTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]