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The map label for this gene is nqrA [H]

Identifier: 113969280

GI number: 113969280

Start: 1094012

End: 1095346

Strand: Direct

Name: nqrA [H]

Synonym: Shewmr4_0936

Alternate gene names: 113969280

Gene position: 1094012-1095346 (Clockwise)

Preceding gene: 113969279

Following gene: 113969281

Centisome position: 23.25

GC content: 47.04

Gene sequence:

>1335_bases
ATGATTACAATTAAGAAAGGATTGGAACTGCCTATAGCAGGCGGACCAGAGCAAGTTATCCATAATGGCCCAGCCATTAA
ACATGTAGCTACTTTGGGTGAAGAGTATATTGGCTTACGTCCAACGATGAAGATCAAAGTGGGCGATAAAGTACAAAAAG
GTCAGGTGATTTTCGAAGATAAGAAAAATCCTGGCGTAAAATATACGGCTTTAGCCAGTGGTACTATATTAGACATTAAC
CGGGGCGCCCAGCGTGTGCTGCAGTCTGTTGTTATTCAAGTAGAAGGTAACGAAAGTGTTTCCTTTGCTAAGTATGACGC
CACTGCTCTCGATACGCTTGACTCGCAACTGGTCCGTGACAACCTGATCGAATCAGGCTTATGGACTGCATTGCGTACAC
GTCCTTTCAGCAAAGTGCCTGCCGTAGATTCTTCTGCCGCTGGTATTTTCGTCACCGCTATTGATACGCAACCCCATGCC
GCCGATCCTGTTGTAGTGATCCGTGAGCATAAAGAAGATTTTGCTAATGGTCTTAAGGTCTTAGCAAGACTTACCGAAGG
TAAAGTTTACCTTTGTAAAGCGCCTGGCGCCGATATTCCTGCCGCTAATGCCCAAGTTGAAGAATTTGCCGGTGTTCACC
CAGCGGGTCTTGTTGGTACTCATATCCATTTCCTACTTCCAGCTTCTGCAAAACGTACTGTTTGGCATGTCGGTTACCAA
GATGTAATAGCCATTGGTCAGCTATTTACTACTGGTCAACTGAATACCGAACGTGTGGTCGCAATTGCCGGTCCTAAAGC
GGCTAAGCCTCGTTTGGTTCGCACTGTTTTAGGTGCAAGCATGACTGAATTGCTCGCGGGCGAAACCTTAGACGGTAACG
TACGTGTTGTTTCAGGTTCTGTGCTGAATGGCCGTACTGCTGTAGGTCCTCAAGGATATTTAGGTCGTTACCACGCGCAG
GTGAGTCTGTTAGAAGAAGGCACTGAAAAAGAATTGTTTGGTTGGGTGTTACCTGGCTCAAACAAATTCTCTATCACCCG
TGCATTCCTTGGCCACTTAAGCGCTTCTCGTCTGTTTAGCATGACAACGAGCACTGGTGGTTCAGACCGCGCTATGGTGC
CAATCGGCAACTACGAGCGTGTAATGCCATTGGATATTCTTCCTACTATGTTGCTGCGTGACCTGATCTCAGGTGACTTT
GACGGTGCTGCCACTTTAGGCGCGTTAGAGTTGGATGAAGAAGATCTCGCACTGTGTACGTTCGTATGTCCAGGCAAATA
TGACTACGGTTCATATCTGCGTGACTGTTTAGATACGATCGAGAGGGAAGGCTAA

Upstream 100 bases:

>100_bases
AAATCTGCGCTAGCTCAATGCAGTAGGTTTTGTTTAAAACCTCAGTATTTAGCAGGAACGCGGCGCATTGTCTTTCCTTC
AAAACGTAGTGCTTGTGGAT

Downstream 100 bases:

>100_bases
TGAGCTTGAAAGATTTTTTCGAACGTATTGAACCCGACTTTGAAAAAGGCGGTAAATACGAAAAGTTTTATGCCCTGTTC
GAAGCGGCATACACCATTTT

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MITIKKGLELPIAGGPEQVIHNGPAIKHVATLGEEYIGLRPTMKIKVGDKVQKGQVIFEDKKNPGVKYTALASGTILDIN
RGAQRVLQSVVIQVEGNESVSFAKYDATALDTLDSQLVRDNLIESGLWTALRTRPFSKVPAVDSSAAGIFVTAIDTQPHA
ADPVVVIREHKEDFANGLKVLARLTEGKVYLCKAPGADIPAANAQVEEFAGVHPAGLVGTHIHFLLPASAKRTVWHVGYQ
DVIAIGQLFTTGQLNTERVVAIAGPKAAKPRLVRTVLGASMTELLAGETLDGNVRVVSGSVLNGRTAVGPQGYLGRYHAQ
VSLLEEGTEKELFGWVLPGSNKFSITRAFLGHLSASRLFSMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLISGDF
DGAATLGALELDEEDLALCTFVCPGKYDYGSYLRDCLDTIEREG

Sequences:

>Translated_444_residues
MITIKKGLELPIAGGPEQVIHNGPAIKHVATLGEEYIGLRPTMKIKVGDKVQKGQVIFEDKKNPGVKYTALASGTILDIN
RGAQRVLQSVVIQVEGNESVSFAKYDATALDTLDSQLVRDNLIESGLWTALRTRPFSKVPAVDSSAAGIFVTAIDTQPHA
ADPVVVIREHKEDFANGLKVLARLTEGKVYLCKAPGADIPAANAQVEEFAGVHPAGLVGTHIHFLLPASAKRTVWHVGYQ
DVIAIGQLFTTGQLNTERVVAIAGPKAAKPRLVRTVLGASMTELLAGETLDGNVRVVSGSVLNGRTAVGPQGYLGRYHAQ
VSLLEEGTEKELFGWVLPGSNKFSITRAFLGHLSASRLFSMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLISGDF
DGAATLGALELDEEDLALCTFVCPGKYDYGSYLRDCLDTIEREG
>Mature_444_residues
MITIKKGLELPIAGGPEQVIHNGPAIKHVATLGEEYIGLRPTMKIKVGDKVQKGQVIFEDKKNPGVKYTALASGTILDIN
RGAQRVLQSVVIQVEGNESVSFAKYDATALDTLDSQLVRDNLIESGLWTALRTRPFSKVPAVDSSAAGIFVTAIDTQPHA
ADPVVVIREHKEDFANGLKVLARLTEGKVYLCKAPGADIPAANAQVEEFAGVHPAGLVGTHIHFLLPASAKRTVWHVGYQ
DVIAIGQLFTTGQLNTERVVAIAGPKAAKPRLVRTVLGASMTELLAGETLDGNVRVVSGSVLNGRTAVGPQGYLGRYHAQ
VSLLEEGTEKELFGWVLPGSNKFSITRAFLGHLSASRLFSMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLISGDF
DGAATLGALELDEEDLALCTFVCPGKYDYGSYLRDCLDTIEREG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008703
- InterPro:   IPR022615 [H]

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB [H]

EC number: NA

Molecular weight: Translated: 47598; Mature: 47598

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIKKGLELPIAGGPEQVIHNGPAIKHVATLGEEYIGLRPTMKIKVGDKVQKGQVIFED
CEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEC
KKNPGVKYTALASGTILDINRGAQRVLQSVVIQVEGNESVSFAKYDATALDTLDSQLVRD
CCCCCEEEEEEECCEEEECCHHHHHHHHHHEEEEECCCCEEEEECCCHHHHHHHHHHHHH
NLIESGLWTALRTRPFSKVPAVDSSAAGIFVTAIDTQPHAADPVVVIREHKEDFANGLKV
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCHHHHHHHHHH
LARLTEGKVYLCKAPGADIPAANAQVEEFAGVHPAGLVGTHIHFLLPASAKRTVWHVGYQ
HHHHCCCCEEEEECCCCCCCCCCCCHHHHCCCCCCCHHHCEEEEEECCCCCCEEEECCHH
DVIAIGQLFTTGQLNTERVVAIAGPKAAKPRLVRTVLGASMTELLAGETLDGNVRVVSGS
HHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHCCHHHHHHCCCCCCCCEEEEECC
VLNGRTAVGPQGYLGRYHAQVSLLEEGTEKELFGWVLPGSNKFSITRAFLGHLSASRLFS
EECCCCCCCCCCCCHHHHHEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHEE
MTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLISGDFDGAATLGALELDEEDLALCT
EEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEE
FVCPGKYDYGSYLRDCLDTIEREG
EECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITIKKGLELPIAGGPEQVIHNGPAIKHVATLGEEYIGLRPTMKIKVGDKVQKGQVIFED
CEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEC
KKNPGVKYTALASGTILDINRGAQRVLQSVVIQVEGNESVSFAKYDATALDTLDSQLVRD
CCCCCEEEEEEECCEEEECCHHHHHHHHHHEEEEECCCCEEEEECCCHHHHHHHHHHHHH
NLIESGLWTALRTRPFSKVPAVDSSAAGIFVTAIDTQPHAADPVVVIREHKEDFANGLKV
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCHHHHHHHHHH
LARLTEGKVYLCKAPGADIPAANAQVEEFAGVHPAGLVGTHIHFLLPASAKRTVWHVGYQ
HHHHCCCCEEEEECCCCCCCCCCCCHHHHCCCCCCCHHHCEEEEEECCCCCCEEEECCHH
DVIAIGQLFTTGQLNTERVVAIAGPKAAKPRLVRTVLGASMTELLAGETLDGNVRVVSGS
HHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHCCHHHHHHCCCCCCCCEEEEECC
VLNGRTAVGPQGYLGRYHAQVSLLEEGTEKELFGWVLPGSNKFSITRAFLGHLSASRLFS
EECCCCCCCCCCCCHHHHHEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHEE
MTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLISGDFDGAATLGALELDEEDLALCT
EEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEE
FVCPGKYDYGSYLRDCLDTIEREG
EECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA