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The map label for this gene is hlyB [H]

Identifier: 113969168

GI number: 113969168

Start: 962790

End: 964454

Strand: Direct

Name: hlyB [H]

Synonym: Shewmr4_0824

Alternate gene names: 113969168

Gene position: 962790-964454 (Clockwise)

Preceding gene: 113969167

Following gene: 113969170

Centisome position: 20.46

GC content: 48.35

Gene sequence:

>1665_bases
ATGTCGAATTTAAGCCTGCGTAATAAATTACTGCTGTTATCTTTGTTTCCCCTCATTTTGACCCTATTTGTGCTCATGAC
CGTCTCCTACTATGTGGAACAGGAATCCCTCGCGGAAGAAGTGGTGACCTTTAGGACTAAGCTGGTGGGCGAACGTAAAC
AACAAATTAAAGAAGCTACCGAAATTGCCGCCGGAATCGTGAAATACCAACTGTCTCTCAAGGAAAATGGCAATGTAAAT
CAAGCCCTGCGTGATATTCGTTTTGGCAGCGCGGGTTACTTCTTTATGTATGACTCACAAGGGAAAAATATTTTCCACGC
TCTGATGCCAAACTTAGAGGGGCAAAACAAAATCGATATGACTGACCCCCGTGGCACTAAGATCATTGTCGGTTTGCTGG
ATGCGGCAAAACGGGGAGACGGTAACTTTTCCTACTATTATCAAAAGCCTAATACTAATGAACAAATTGAGAAGATAAGC
TATGTGATGATGGTTCCTGGCACCGACTGGATGTTAGGTACTGGAGCTTATATCGACGATATCGAAGCGGTTGTCGAGGA
TTATCGCCAAACCGTAACTGAGCAGATGGACGAAAAATCTTTCATGATCTTATTGATCGCCCTTGCGCTCACAGGGATCA
CGGCCTTTATCATCATGATGGCAGCCCATCGTATGGTCGTACCGATTAAACACATGGCGGATAATCTTAATGATATTGCC
AAGGGGGAAGGGGACTTAACCAAACGCTTAAGTGTTAAGGGAGCAGATGAGATTGCCCAATTAGGTCAAGCCTTTAACTT
GTTCGTCGATAAGCTGCAAAACATTATCGGCGATGTAGCGAATGCGACGGCGAAAGTAAAATCCGCCGCCAACGCGATTC
ACGACCAAACCAAAGTGATGTCAAGGCAGCTACTTAGCCACAACAACGAAACAGACCAAGTGGTGACGGCCATTACCGAG
ATGTCGTCTACTGCGAGTGAAGTGGCGCAAAATACCACTCAAGTGGCCGAGGCGACCCACGCGGCGACGGGTGATGTAGC
CAATGCTCAGCGCTGCGTCGATGCCTCACTCGAAGAGATTGCAGGTCTTATGGCGCAAATCAATAATGCCGCTGGCAGCA
TTAAATCCTTAAGTGAGCAATCGCAAAAGATTAACAGTGTCTTGTCGGTAATCGGTGGCATTGCCGAGCAAACCAACCTG
CTGGCCCTCAACGCGGCGATTGAAGCAGCCCGCGCCGGTGAACAGGGTCGAGGCTTTGCCGTGGTGGCCGATGAAGTGCG
TAATCTTGCCAGCCGTACTCAGGCAAGTACCTTAGAAATCAACGAAATGCTTTCAGAACTCCACAAGCTGGTGGCCTTAG
CGGTAAAAACCATGGATGAAAGCCAACAGAGCTGCGTGCGCTCGGTGGATTCTTCCCGCGCTATTTCGGAAAGCTTAGGC
TCAGTGACATCGGCGGTGACTGCGATTAACGATATGAGTACCCAAATTGCGACGGCGGCGACCGAGCAAAGTTCAGTGAC
CGAAGAAATCAACCGTAACGTTTATGCCATCCAAGAAATCGTTAACGAGCTGCTGCACTCCAGTGAAGATGCGGCCAAGG
TGAGTCAAACCGTGTCTCAGGAAGGGGTTAACCTGGGTAAATTGGTGGGACAGTTTAAGATTTAA

Upstream 100 bases:

>100_bases
TACAATATTTGTTAAGTCAAACCCAAAGATGTTGCACTGTTTTGGCTATACTTCAGACATATTAAAAAAAATAAGCTCGA
TCACCCTGGAGTAAGCAAGC

Downstream 100 bases:

>100_bases
CTCGGCTAATTAAACAAGTTAATTAAGTTAGCGAATAAAGACGGGAGACAGTGTCTCCCGTTTTTTATGTTTATCTTTGG
GCTTAATTTTATGCTTGCAA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MSNLSLRNKLLLLSLFPLILTLFVLMTVSYYVEQESLAEEVVTFRTKLVGERKQQIKEATEIAAGIVKYQLSLKENGNVN
QALRDIRFGSAGYFFMYDSQGKNIFHALMPNLEGQNKIDMTDPRGTKIIVGLLDAAKRGDGNFSYYYQKPNTNEQIEKIS
YVMMVPGTDWMLGTGAYIDDIEAVVEDYRQTVTEQMDEKSFMILLIALALTGITAFIIMMAAHRMVVPIKHMADNLNDIA
KGEGDLTKRLSVKGADEIAQLGQAFNLFVDKLQNIIGDVANATAKVKSAANAIHDQTKVMSRQLLSHNNETDQVVTAITE
MSSTASEVAQNTTQVAEATHAATGDVANAQRCVDASLEEIAGLMAQINNAAGSIKSLSEQSQKINSVLSVIGGIAEQTNL
LALNAAIEAARAGEQGRGFAVVADEVRNLASRTQASTLEINEMLSELHKLVALAVKTMDESQQSCVRSVDSSRAISESLG
SVTSAVTAINDMSTQIATAATEQSSVTEEINRNVYAIQEIVNELLHSSEDAAKVSQTVSQEGVNLGKLVGQFKI

Sequences:

>Translated_554_residues
MSNLSLRNKLLLLSLFPLILTLFVLMTVSYYVEQESLAEEVVTFRTKLVGERKQQIKEATEIAAGIVKYQLSLKENGNVN
QALRDIRFGSAGYFFMYDSQGKNIFHALMPNLEGQNKIDMTDPRGTKIIVGLLDAAKRGDGNFSYYYQKPNTNEQIEKIS
YVMMVPGTDWMLGTGAYIDDIEAVVEDYRQTVTEQMDEKSFMILLIALALTGITAFIIMMAAHRMVVPIKHMADNLNDIA
KGEGDLTKRLSVKGADEIAQLGQAFNLFVDKLQNIIGDVANATAKVKSAANAIHDQTKVMSRQLLSHNNETDQVVTAITE
MSSTASEVAQNTTQVAEATHAATGDVANAQRCVDASLEEIAGLMAQINNAAGSIKSLSEQSQKINSVLSVIGGIAEQTNL
LALNAAIEAARAGEQGRGFAVVADEVRNLASRTQASTLEINEMLSELHKLVALAVKTMDESQQSCVRSVDSSRAISESLG
SVTSAVTAINDMSTQIATAATEQSSVTEEINRNVYAIQEIVNELLHSSEDAAKVSQTVSQEGVNLGKLVGQFKI
>Mature_553_residues
SNLSLRNKLLLLSLFPLILTLFVLMTVSYYVEQESLAEEVVTFRTKLVGERKQQIKEATEIAAGIVKYQLSLKENGNVNQ
ALRDIRFGSAGYFFMYDSQGKNIFHALMPNLEGQNKIDMTDPRGTKIIVGLLDAAKRGDGNFSYYYQKPNTNEQIEKISY
VMMVPGTDWMLGTGAYIDDIEAVVEDYRQTVTEQMDEKSFMILLIALALTGITAFIIMMAAHRMVVPIKHMADNLNDIAK
GEGDLTKRLSVKGADEIAQLGQAFNLFVDKLQNIIGDVANATAKVKSAANAIHDQTKVMSRQLLSHNNETDQVVTAITEM
SSTASEVAQNTTQVAEATHAATGDVANAQRCVDASLEEIAGLMAQINNAAGSIKSLSEQSQKINSVLSVIGGIAEQTNLL
ALNAAIEAARAGEQGRGFAVVADEVRNLASRTQASTLEINEMLSELHKLVALAVKTMDESQQSCVRSVDSSRAISESLGS
VTSAVTAINDMSTQIATAATEQSSVTEEINRNVYAIQEIVNELLHSSEDAAKVSQTVSQEGVNLGKLVGQFKI

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=312, Percent_Identity=32.0512820512821, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1787690, Length=355, Percent_Identity=27.887323943662, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1788195, Length=297, Percent_Identity=29.6296296296296, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1788194, Length=341, Percent_Identity=28.7390029325513, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1789453, Length=338, Percent_Identity=27.810650887574, Blast_Score=93, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 60102; Mature: 59971

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLSLRNKLLLLSLFPLILTLFVLMTVSYYVEQESLAEEVVTFRTKLVGERKQQIKEAT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIAAGIVKYQLSLKENGNVNQALRDIRFGSAGYFFMYDSQGKNIFHALMPNLEGQNKIDM
HHHHHHHHHHEECCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCC
TDPRGTKIIVGLLDAAKRGDGNFSYYYQKPNTNEQIEKISYVMMVPGTDWMLGTGAYIDD
CCCCCCEEEEEEHHHHCCCCCCEEEEEECCCCHHHHHHHHEEEEECCCCCEEECCCHHHH
IEAVVEDYRQTVTEQMDEKSFMILLIALALTGITAFIIMMAAHRMVVPIKHMADNLNDIA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KGEGDLTKRLSVKGADEIAQLGQAFNLFVDKLQNIIGDVANATAKVKSAANAIHDQTKVM
CCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRQLLSHNNETDQVVTAITEMSSTASEVAQNTTQVAEATHAATGDVANAQRCVDASLEEI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AGLMAQINNAAGSIKSLSEQSQKINSVLSVIGGIAEQTNLLALNAAIEAARAGEQGRGFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEE
VVADEVRNLASRTQASTLEINEMLSELHKLVALAVKTMDESQQSCVRSVDSSRAISESLG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVTSAVTAINDMSTQIATAATEQSSVTEEINRNVYAIQEIVNELLHSSEDAAKVSQTVSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
EGVNLGKLVGQFKI
CCCHHHHHHHHCCC
>Mature Secondary Structure 
SNLSLRNKLLLLSLFPLILTLFVLMTVSYYVEQESLAEEVVTFRTKLVGERKQQIKEAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIAAGIVKYQLSLKENGNVNQALRDIRFGSAGYFFMYDSQGKNIFHALMPNLEGQNKIDM
HHHHHHHHHHEECCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCC
TDPRGTKIIVGLLDAAKRGDGNFSYYYQKPNTNEQIEKISYVMMVPGTDWMLGTGAYIDD
CCCCCCEEEEEEHHHHCCCCCCEEEEEECCCCHHHHHHHHEEEEECCCCCEEECCCHHHH
IEAVVEDYRQTVTEQMDEKSFMILLIALALTGITAFIIMMAAHRMVVPIKHMADNLNDIA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KGEGDLTKRLSVKGADEIAQLGQAFNLFVDKLQNIIGDVANATAKVKSAANAIHDQTKVM
CCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRQLLSHNNETDQVVTAITEMSSTASEVAQNTTQVAEATHAATGDVANAQRCVDASLEEI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AGLMAQINNAAGSIKSLSEQSQKINSVLSVIGGIAEQTNLLALNAAIEAARAGEQGRGFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEE
VVADEVRNLASRTQASTLEINEMLSELHKLVALAVKTMDESQQSCVRSVDSSRAISESLG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVTSAVTAINDMSTQIATAATEQSSVTEEINRNVYAIQEIVNELLHSSEDAAKVSQTVSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
EGVNLGKLVGQFKI
CCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]