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The map label for this gene is xerD [H]

Identifier: 113969139

GI number: 113969139

Start: 929869

End: 930771

Strand: Direct

Name: xerD [H]

Synonym: Shewmr4_0795

Alternate gene names: 113969139

Gene position: 929869-930771 (Clockwise)

Preceding gene: 113969138

Following gene: 113969140

Centisome position: 19.76

GC content: 51.38

Gene sequence:

>903_bases
GTGGCTAAAACCTATCAGTGCGATCCGCTTATCGATGCCTTTCTCGATGATCTTTGGTCCAGTAAGGGCTTAAGTGATAA
CACCTTGAGTGCCTATCGCACCGATTTACGCCATTTTGACCGCTATCAACAGAGCCAAGGCCTGCGGTTAATCGAGGTGG
TGCAAGCCGATGTGCGCGCCTATTTAGCCTACCGAGTCGAACAACAATTTGCCCGCACCAGTAGCGCACGTCTACTTAGC
AGTTTACGGCGTTTTTATACTTATTTATTGCAGACCAAGCAGATTGCTGGCGATCCTATGGCGCTGATCGAATCGCCCAA
ATTGAGTCGGCAATTGCCAGATTCCTTAAGTGAGTCACAGGTCGATAGATTGCTGGCCGAGCCCAATGTGGACGACCCAG
TTGAGTGCCGTGATAAAGCCATGCTTGAACTCTTATATGCGACTGGATTGCGGGTGAGTGAGCTGGTGGGGCTCACTCTG
GAGCAGATGAGTTTGCGCCAAGGTCTAGTGCGGATTGTGGGTAAGGGCGGTAAAGAACGGTTAGTGCCTATGGGCGAGCT
GGCCATTACCGAGGTTGAACGCTACTTAAGCTCTGCGCGCCATGAGTTGTTGGGCAATGTCCAGTCCGATGTGGTATTTC
CATCTAAGCGCTCGCAGATGATGACGCGGCAAACTTTCTGGCATAGGATCAAGCTCTACGCGAGCCGTGCCGGCATCGAA
ACTGAACTTTCACCCCATACCCTGCGCCATGCCTTTGCGACCCACTTACTCAACCATGGCGCCGACCTTAGGGTGGTACA
ATTACTCTTAGGTCACAGTGACTTATCGACGACTCAAATTTATACCCATGTGGCGCGAGCGAGATTACAAGAGCTACATC
AACAGCATCATCCTCGTGGTTAA

Upstream 100 bases:

>100_bases
GCGGTCAGCGCGGCATAAACAAGACGCTGCCACAAGCAGAACAATTGAGTTAATATCAACGGCGTATCCTTAGAATACGC
CGTTTTTTTATGGAGTTTTT

Downstream 100 bases:

>100_bases
GTTGGATCCTTCACAAAACCGCGAATGGTTGAATTTAGTTACAGTATAAATTTGCATTCTATCTAGCTTGTCTGTAACTT
TTTGCCCCCATACAGGGTCT

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MAKTYQCDPLIDAFLDDLWSSKGLSDNTLSAYRTDLRHFDRYQQSQGLRLIEVVQADVRAYLAYRVEQQFARTSSARLLS
SLRRFYTYLLQTKQIAGDPMALIESPKLSRQLPDSLSESQVDRLLAEPNVDDPVECRDKAMLELLYATGLRVSELVGLTL
EQMSLRQGLVRIVGKGGKERLVPMGELAITEVERYLSSARHELLGNVQSDVVFPSKRSQMMTRQTFWHRIKLYASRAGIE
TELSPHTLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVARARLQELHQQHHPRG

Sequences:

>Translated_300_residues
MAKTYQCDPLIDAFLDDLWSSKGLSDNTLSAYRTDLRHFDRYQQSQGLRLIEVVQADVRAYLAYRVEQQFARTSSARLLS
SLRRFYTYLLQTKQIAGDPMALIESPKLSRQLPDSLSESQVDRLLAEPNVDDPVECRDKAMLELLYATGLRVSELVGLTL
EQMSLRQGLVRIVGKGGKERLVPMGELAITEVERYLSSARHELLGNVQSDVVFPSKRSQMMTRQTFWHRIKLYASRAGIE
TELSPHTLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVARARLQELHQQHHPRG
>Mature_299_residues
AKTYQCDPLIDAFLDDLWSSKGLSDNTLSAYRTDLRHFDRYQQSQGLRLIEVVQADVRAYLAYRVEQQFARTSSARLLSS
LRRFYTYLLQTKQIAGDPMALIESPKLSRQLPDSLSESQVDRLLAEPNVDDPVECRDKAMLELLYATGLRVSELVGLTLE
QMSLRQGLVRIVGKGGKERLVPMGELAITEVERYLSSARHELLGNVQSDVVFPSKRSQMMTRQTFWHRIKLYASRAGIET
ELSPHTLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVARARLQELHQQHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=291, Percent_Identity=62.5429553264605, Blast_Score=355, Evalue=2e-99,
Organism=Escherichia coli, GI1790244, Length=280, Percent_Identity=36.0714285714286, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1790768, Length=162, Percent_Identity=32.0987654320988, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790767, Length=173, Percent_Identity=29.4797687861272, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34206; Mature: 34074

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTYQCDPLIDAFLDDLWSSKGLSDNTLSAYRTDLRHFDRYQQSQGLRLIEVVQADVRA
CCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YLAYRVEQQFARTSSARLLSSLRRFYTYLLQTKQIAGDPMALIESPKLSRQLPDSLSESQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHCCCHHHHHH
VDRLLAEPNVDDPVECRDKAMLELLYATGLRVSELVGLTLEQMSLRQGLVRIVGKGGKER
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LVPMGELAITEVERYLSSARHELLGNVQSDVVFPSKRSQMMTRQTFWHRIKLYASRAGIE
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
TELSPHTLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVARARLQELHQQHHPRG
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKTYQCDPLIDAFLDDLWSSKGLSDNTLSAYRTDLRHFDRYQQSQGLRLIEVVQADVRA
CCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YLAYRVEQQFARTSSARLLSSLRRFYTYLLQTKQIAGDPMALIESPKLSRQLPDSLSESQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHCCCHHHHHH
VDRLLAEPNVDDPVECRDKAMLELLYATGLRVSELVGLTLEQMSLRQGLVRIVGKGGKER
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LVPMGELAITEVERYLSSARHELLGNVQSDVVFPSKRSQMMTRQTFWHRIKLYASRAGIE
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
TELSPHTLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVARARLQELHQQHHPRG
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]