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The map label for this gene is sdaC [H]

Identifier: 113969105

GI number: 113969105

Start: 887781

End: 889073

Strand: Direct

Name: sdaC [H]

Synonym: Shewmr4_0761

Alternate gene names: 113969105

Gene position: 887781-889073 (Clockwise)

Preceding gene: 113969104

Following gene: 113969107

Centisome position: 18.86

GC content: 48.88

Gene sequence:

>1293_bases
ATGCAAAAAGATGCGATCAGTGTTCTCGAAACACCTCAAAGCACGCAAGAAAACACAACAAGACACTTACCATGGACGCG
CCAAGACACGACTTGGATGCTAAGTTTATTTGGCACCGCTGTGGGGGCGGGCATTCTATTTCTTCCAATCAATGCGGGCA
TGGGCGGTTTTTGGCCCTTAGTCTTGATGGCCATTATCATTGGGCCTATGACCTATCTCGCGCACCGTGGCCTATCGCGC
TTCGTATGTTCATCGAGCATTCCCGGCAGTGACATTACCCAAGTGGTCGAAGAACACTTTGGGATTGGCGCGGGCAAGGC
GATTACGCTGCTGTATTTTTTAGCGATTTATCCCATCGTATTGATCTACGGCGTGGGGATCACTAATACCGTCGACAGCT
TTATCGTCAACCAATTGGGCATGGCTTCACCGCCACGTTTTTTGCTGTCTGGCATTTTGATTTTCGGCATGATGGCTGTG
ATGGTCTCTGGTGAGCAATTTATGCTGAAGGTGACTCAGTTGCTGGTGTATCCGCTGGTGGGCATTTTAGCCTTTATGTC
CATCTATCTGGTCCCAGAGTGGAAAATGGATGCGCTGCAAGTCGTGCCAGAAACGGGCGCCTTTTTAGGCACAGTATGGT
TAACCATTCCTGTACTGGTGTTTGCCTTTAATCATTCTCCGGCGATTTCGCAATTTTCGGTTTCCCTTAAGCGTGACCAT
GGGGCCAACGCGGCCCGTAAGGCCGATGTGATCCTGCGTAATACCTCGATGATGTTAGTCGGCTTTGTGATGTTATTCGT
GTTCTCCTGCGTCTTGTCACTGTCGCCAGAACAGTTGGCTGAAGCGAAGTCGAAGAACCTGCCGATTTTATCTTACCTTG
CGAACGTGCATGACAGTGGTTTTGTCAGCTATTTCGGGCCTTTCATCGCGTTTGTGGCGATTGTATCTTCTTTCTTTGGC
CACTACATGGGGGCGACTGAGGGCATGAAGGGCATTATCGTTAAGCAGCTGCGTTCAAGTAACAAACAAATCAGTGAGAA
CAAGCTGAACAATTTTATCTTAGTGTTTATGTTTGCCACGATTTGGGCCGTTGCGATTATAAACCCAAGTATTTTGGGAA
TGATCGAGGCGCTGGGCGGCCCGATTATTGCGGCGATTTTGTACTTAATGCCAATGTATGCCGTGTACAAAGTGCCGGCG
CTGAAGGCTTATCGAAACCGCATCAGCAACGTATTTGTGATTATTGCGGGCCTACTGGCGATGACCGCCATTCTGTTTGG
TCTCCTGAGATAA

Upstream 100 bases:

>100_bases
TTTCATTACTTAAAATAGTGTTAGATCAACTTTTGCTAAAGCTTTTTCGTTATCCTTACGTCGAATTTTTTATGCGGTAT
CACCGTAAGGTAATTTTAAT

Downstream 100 bases:

>100_bases
GCTTGAGATTTATTGCCGTTTGAAATGAAGGATCGGGTTATGCCCGATCCTTTTTTATTACTTCTCTTCGTACATCAGAT
AGTAACTCTGCTTCATCCCT

Product: amino acid transporter, transmembrane

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MQKDAISVLETPQSTQENTTRHLPWTRQDTTWMLSLFGTAVGAGILFLPINAGMGGFWPLVLMAIIIGPMTYLAHRGLSR
FVCSSSIPGSDITQVVEEHFGIGAGKAITLLYFLAIYPIVLIYGVGITNTVDSFIVNQLGMASPPRFLLSGILIFGMMAV
MVSGEQFMLKVTQLLVYPLVGILAFMSIYLVPEWKMDALQVVPETGAFLGTVWLTIPVLVFAFNHSPAISQFSVSLKRDH
GANAARKADVILRNTSMMLVGFVMLFVFSCVLSLSPEQLAEAKSKNLPILSYLANVHDSGFVSYFGPFIAFVAIVSSFFG
HYMGATEGMKGIIVKQLRSSNKQISENKLNNFILVFMFATIWAVAIINPSILGMIEALGGPIIAAILYLMPMYAVYKVPA
LKAYRNRISNVFVIIAGLLAMTAILFGLLR

Sequences:

>Translated_430_residues
MQKDAISVLETPQSTQENTTRHLPWTRQDTTWMLSLFGTAVGAGILFLPINAGMGGFWPLVLMAIIIGPMTYLAHRGLSR
FVCSSSIPGSDITQVVEEHFGIGAGKAITLLYFLAIYPIVLIYGVGITNTVDSFIVNQLGMASPPRFLLSGILIFGMMAV
MVSGEQFMLKVTQLLVYPLVGILAFMSIYLVPEWKMDALQVVPETGAFLGTVWLTIPVLVFAFNHSPAISQFSVSLKRDH
GANAARKADVILRNTSMMLVGFVMLFVFSCVLSLSPEQLAEAKSKNLPILSYLANVHDSGFVSYFGPFIAFVAIVSSFFG
HYMGATEGMKGIIVKQLRSSNKQISENKLNNFILVFMFATIWAVAIINPSILGMIEALGGPIIAAILYLMPMYAVYKVPA
LKAYRNRISNVFVIIAGLLAMTAILFGLLR
>Mature_430_residues
MQKDAISVLETPQSTQENTTRHLPWTRQDTTWMLSLFGTAVGAGILFLPINAGMGGFWPLVLMAIIIGPMTYLAHRGLSR
FVCSSSIPGSDITQVVEEHFGIGAGKAITLLYFLAIYPIVLIYGVGITNTVDSFIVNQLGMASPPRFLLSGILIFGMMAV
MVSGEQFMLKVTQLLVYPLVGILAFMSIYLVPEWKMDALQVVPETGAFLGTVWLTIPVLVFAFNHSPAISQFSVSLKRDH
GANAARKADVILRNTSMMLVGFVMLFVFSCVLSLSPEQLAEAKSKNLPILSYLANVHDSGFVSYFGPFIAFVAIVSSFFG
HYMGATEGMKGIIVKQLRSSNKQISENKLNNFILVFMFATIWAVAIINPSILGMIEALGGPIIAAILYLMPMYAVYKVPA
LKAYRNRISNVFVIIAGLLAMTAILFGLLR

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=427, Percent_Identity=55.0351288056206, Blast_Score=455, Evalue=1e-129,
Organism=Escherichia coli, GI1789504, Length=443, Percent_Identity=41.9864559819413, Blast_Score=341, Evalue=6e-95,
Organism=Escherichia coli, GI1789211, Length=408, Percent_Identity=35.5392156862745, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1789961, Length=400, Percent_Identity=27, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI145693183, Length=434, Percent_Identity=24.8847926267281, Blast_Score=126, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 46976; Mature: 46976

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKDAISVLETPQSTQENTTRHLPWTRQDTTWMLSLFGTAVGAGILFLPINAGMGGFWPL
CCCHHHHHHCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHH
VLMAIIIGPMTYLAHRGLSRFVCSSSIPGSDITQVVEEHFGIGAGKAITLLYFLAIYPIV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LIYGVGITNTVDSFIVNQLGMASPPRFLLSGILIFGMMAVMVSGEQFMLKVTQLLVYPLV
HHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GILAFMSIYLVPEWKMDALQVVPETGAFLGTVWLTIPVLVFAFNHSPAISQFSVSLKRDH
HHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
GANAARKADVILRNTSMMLVGFVMLFVFSCVLSLSPEQLAEAKSKNLPILSYLANVHDSG
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCC
FVSYFGPFIAFVAIVSSFFGHYMGATEGMKGIIVKQLRSSNKQISENKLNNFILVFMFAT
HHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IWAVAIINPSILGMIEALGGPIIAAILYLMPMYAVYKVPALKAYRNRISNVFVIIAGLLA
HHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTAILFGLLR
HHHHHHHHCC
>Mature Secondary Structure
MQKDAISVLETPQSTQENTTRHLPWTRQDTTWMLSLFGTAVGAGILFLPINAGMGGFWPL
CCCHHHHHHCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHH
VLMAIIIGPMTYLAHRGLSRFVCSSSIPGSDITQVVEEHFGIGAGKAITLLYFLAIYPIV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LIYGVGITNTVDSFIVNQLGMASPPRFLLSGILIFGMMAVMVSGEQFMLKVTQLLVYPLV
HHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GILAFMSIYLVPEWKMDALQVVPETGAFLGTVWLTIPVLVFAFNHSPAISQFSVSLKRDH
HHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
GANAARKADVILRNTSMMLVGFVMLFVFSCVLSLSPEQLAEAKSKNLPILSYLANVHDSG
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCC
FVSYFGPFIAFVAIVSSFFGHYMGATEGMKGIIVKQLRSSNKQISENKLNNFILVFMFAT
HHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IWAVAIINPSILGMIEALGGPIIAAILYLMPMYAVYKVPALKAYRNRISNVFVIIAGLLA
HHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTAILFGLLR
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]