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The map label for this gene is bla [H]

Identifier: 113969038

GI number: 113969038

Start: 801850

End: 802647

Strand: Direct

Name: bla [H]

Synonym: Shewmr4_0694

Alternate gene names: 113969038

Gene position: 801850-802647 (Clockwise)

Preceding gene: 113969029

Following gene: 113969040

Centisome position: 17.04

GC content: 47.24

Gene sequence:

>798_bases
ATGCGTGCGTTAGCCTTATCGGCTGTGTTGATGGTGACAACGATGATTGGCATGCCTGCGGTGGCAAAGGAGTGGCAAGA
GAACAAGAGCTGGAATGCTCACTTTAGCGAACATAAAACCCAAGGCGTGGTTGTGCTCTGGAACGAGAATACACAGCAGG
GTTTTACTAACGATCTTAAACGGGCAAACCAAGCATTTTTACCGGCATCGACCTTTAAGATCCCAAACAGTTTAATTGCC
TTGGACTTAGGTGTGGTTAAGGATGAGCATCAGGTCTTTAAATGGGATGGACAGACGCGAGATATCGCCGCATGGAATCG
TGACCATGATTTAATCACCGCGATGAAGTATTCGGTTGTGCCTGTTTATCAAGAATTTGCCCGCCAAATTGGCGAGGCTC
GTATGAATAAAATGCTGCACGCCTTCGATTATGGCAATGAGGATATCTCGGGCAATTTGGACAGTTTTTGGCTCGATGGT
GGTATTCGCATTTCGGCTACCCAGCAAATCGCTTTTTTACGCAAGCTGTACCACAACAAGCTGCACGTTTCTGAGCGTAG
TCAGCGCATCGTGAAACAAGCCATGCTGACCGAGGCAAATGCCGACTATATCATCCGAGCGAAAACCGGCTATTCGGTCA
GAATTGAACCGAAAATCGGTTGGTGGGTTGGCTGGGTCGAACTGGATGATAATGTGTGGTTTTTCGCGACCAATATGGAT
ATGCCTTCCGCTGAGGGCTTAGGGTTACGTCAAAGCATTACGAAAGCAGTGCTGAAACAGGAAAAAATTATTCCTTAG

Upstream 100 bases:

>100_bases
GCCACAATTGGTCAGCAGTTTGCTAGGGAAAGCCCGCCAAGACGGTGCTACTCTTAGCGCCTCATTTTTATGGATTTATT
GCATTAGGCAAGGGGACATT

Downstream 100 bases:

>100_bases
AAGTGGTTAGCGGCGCATTTGTGTAAAATAGCCGTCATATAAGCTGTAAAGATATATGGACAAAATGCTTATGCTTATGC
TGATGCGCTCATAGCTAATT

Product: Beta-lactamase

Products: NA

Alternate protein names: Beta-lactamase PSE-2 [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MRALALSAVLMVTTMIGMPAVAKEWQENKSWNAHFSEHKTQGVVVLWNENTQQGFTNDLKRANQAFLPASTFKIPNSLIA
LDLGVVKDEHQVFKWDGQTRDIAAWNRDHDLITAMKYSVVPVYQEFARQIGEARMNKMLHAFDYGNEDISGNLDSFWLDG
GIRISATQQIAFLRKLYHNKLHVSERSQRIVKQAMLTEANADYIIRAKTGYSVRIEPKIGWWVGWVELDDNVWFFATNMD
MPSAEGLGLRQSITKAVLKQEKIIP

Sequences:

>Translated_265_residues
MRALALSAVLMVTTMIGMPAVAKEWQENKSWNAHFSEHKTQGVVVLWNENTQQGFTNDLKRANQAFLPASTFKIPNSLIA
LDLGVVKDEHQVFKWDGQTRDIAAWNRDHDLITAMKYSVVPVYQEFARQIGEARMNKMLHAFDYGNEDISGNLDSFWLDG
GIRISATQQIAFLRKLYHNKLHVSERSQRIVKQAMLTEANADYIIRAKTGYSVRIEPKIGWWVGWVELDDNVWFFATNMD
MPSAEGLGLRQSITKAVLKQEKIIP
>Mature_265_residues
MRALALSAVLMVTTMIGMPAVAKEWQENKSWNAHFSEHKTQGVVVLWNENTQQGFTNDLKRANQAFLPASTFKIPNSLIA
LDLGVVKDEHQVFKWDGQTRDIAAWNRDHDLITAMKYSVVPVYQEFARQIGEARMNKMLHAFDYGNEDISGNLDSFWLDG
GIRISATQQIAFLRKLYHNKLHVSERSQRIVKQAMLTEANADYIIRAKTGYSVRIEPKIGWWVGWVELDDNVWFFATNMD
MPSAEGLGLRQSITKAVLKQEKIIP

Specific function: Hydrolyzes both carbenicillin and oxacillin [H]

COG id: COG2602

COG function: function code V; Beta-lactamase class D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-D beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR002137
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 30270; Mature: 30270

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS00337 BETA_LACTAMASE_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALALSAVLMVTTMIGMPAVAKEWQENKSWNAHFSEHKTQGVVVLWNENTQQGFTNDLK
CCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHH
RANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIAAWNRDHDLITAMKYSVV
HHCCCCCCCHHHCCCCCEEEEEECEECCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHH
PVYQEFARQIGEARMNKMLHAFDYGNEDISGNLDSFWLDGGIRISATQQIAFLRKLYHNK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEHHHHHHHHHHHHHCC
LHVSERSQRIVKQAMLTEANADYIIRAKTGYSVRIEPKIGWWVGWVELDDNVWFFATNMD
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCEEEEEEEECCCEEEEEECCC
MPSAEGLGLRQSITKAVLKQEKIIP
CCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRALALSAVLMVTTMIGMPAVAKEWQENKSWNAHFSEHKTQGVVVLWNENTQQGFTNDLK
CCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHH
RANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIAAWNRDHDLITAMKYSVV
HHCCCCCCCHHHCCCCCEEEEEECEECCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHH
PVYQEFARQIGEARMNKMLHAFDYGNEDISGNLDSFWLDGGIRISATQQIAFLRKLYHNK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEHHHHHHHHHHHHHCC
LHVSERSQRIVKQAMLTEANADYIIRAKTGYSVRIEPKIGWWVGWVELDDNVWFFATNMD
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCEEEEEEEECCCEEEEEECCC
MPSAEGLGLRQSITKAVLKQEKIIP
CCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3126705; 11188693 [H]