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The map label for this gene is pabA [H]

Identifier: 113968951

GI number: 113968951

Start: 699488

End: 700099

Strand: Direct

Name: pabA [H]

Synonym: Shewmr4_0607

Alternate gene names: 113968951

Gene position: 699488-700099 (Clockwise)

Preceding gene: 113968950

Following gene: 113968952

Centisome position: 14.86

GC content: 48.37

Gene sequence:

>612_bases
ATGTTGCTAATGATCGACAATTACGACTCTTTCACCTTTAACTTAGTGCAGTATTTTCAGCAGTTAGGGCAAGAGATTGT
GGTTAAACGCAATGATGAAATCAGCTTAGCGGAAATCGAGGCGCTGGCACCGAGCCATTTAGTCATCTCTCCCGGGCCTT
GTTCGCCCAATGAAGCGGGGATTTCCCTCGCGGCGATTGAGCATTTTGCCACTCGTTTACCTATCCTGGGTGTGTGTTTA
GGGCATCAAGCCATGGCGCAGGTGTTTGGTGCTAAGGTTGTGCGAGCGCAGCGAGTGATGCATGGCAAAGTCAGTGCGAT
TGGCCATACAGGCGAGCGCTTATTCAAAGGGTTAAATCAACCATTAACTGTAACACGCTACCATTCATTGTTGGTCGATG
CTGTCCCTGAGGGATTTGTGTTAGATGCTTGGTTTGACGACCCAACCCATGGACGCGAAATTATGGCCATGAGTCATAAG
CAGCTGCCACTCTTTGGTGTGCAATTTCACCCCGAGTCAATTTTGACCGAGCAAGGCCATGAATTGTTGGCAAACTTCTT
GTCTCAATCTGCTCTTACTTGCGGTCATAAGAGCAGCTCGTCATTTGAGTAG

Upstream 100 bases:

>100_bases
TTGCCATAAAGGCTTAATCCGCGAGGTGGGCTGTGGTAGCATTTGCGCCGCATTTCATTCATGGATTGCATCGACTACCA
TTTGAGCTAATGGATTTTGT

Downstream 100 bases:

>100_bases
AATAACTACACTTCATTCCTCGTTTCGCGAGCACATGCTTGTCAGAACGAACAAAATTTAATCTCGAAACGTCAACACGC
CCTAAGCTTTGTTACAAGAT

Product: aminodeoxychorismate synthase, glutamine amidotransferase subunit

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MLLMIDNYDSFTFNLVQYFQQLGQEIVVKRNDEISLAEIEALAPSHLVISPGPCSPNEAGISLAAIEHFATRLPILGVCL
GHQAMAQVFGAKVVRAQRVMHGKVSAIGHTGERLFKGLNQPLTVTRYHSLLVDAVPEGFVLDAWFDDPTHGREIMAMSHK
QLPLFGVQFHPESILTEQGHELLANFLSQSALTCGHKSSSSFE

Sequences:

>Translated_203_residues
MLLMIDNYDSFTFNLVQYFQQLGQEIVVKRNDEISLAEIEALAPSHLVISPGPCSPNEAGISLAAIEHFATRLPILGVCL
GHQAMAQVFGAKVVRAQRVMHGKVSAIGHTGERLFKGLNQPLTVTRYHSLLVDAVPEGFVLDAWFDDPTHGREIMAMSHK
QLPLFGVQFHPESILTEQGHELLANFLSQSALTCGHKSSSSFE
>Mature_203_residues
MLLMIDNYDSFTFNLVQYFQQLGQEIVVKRNDEISLAEIEALAPSHLVISPGPCSPNEAGISLAAIEHFATRLPILGVCL
GHQAMAQVFGAKVVRAQRVMHGKVSAIGHTGERLFKGLNQPLTVTRYHSLLVDAVPEGFVLDAWFDDPTHGREIMAMSHK
QLPLFGVQFHPESILTEQGHELLANFLSQSALTCGHKSSSSFE

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=149, Percent_Identity=32.2147651006711, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789760, Length=189, Percent_Identity=65.6084656084656, Blast_Score=258, Evalue=1e-70,
Organism=Escherichia coli, GI1787517, Length=190, Percent_Identity=41.5789473684211, Blast_Score=149, Evalue=9e-38,
Organism=Escherichia coli, GI1788854, Length=194, Percent_Identity=27.319587628866, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI133901714, Length=150, Percent_Identity=32.6666666666667, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71992717, Length=150, Percent_Identity=32.6666666666667, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71992710, Length=150, Percent_Identity=32.6666666666667, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322638, Length=202, Percent_Identity=43.5643564356436, Blast_Score=166, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324361, Length=212, Percent_Identity=32.0754716981132, Blast_Score=82, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6323873, Length=145, Percent_Identity=30.3448275862069, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281365319, Length=143, Percent_Identity=30.0699300699301, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 22319; Mature: 22319

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLMIDNYDSFTFNLVQYFQQLGQEIVVKRNDEISLAEIEALAPSHLVISPGPCSPNEAG
CEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHCCCCEEEEECCCCCCCCCC
ISLAAIEHFATRLPILGVCLGHQAMAQVFGAKVVRAQRVMHGKVSAIGHTGERLFKGLNQ
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
PLTVTRYHSLLVDAVPEGFVLDAWFDDPTHGREIMAMSHKQLPLFGVQFHPESILTEQGH
CEEHHHHHHHHHHHCCCCEEEEEECCCCCCCHHEEHHCCCCCCEEEEEECCHHHHHHHHH
ELLANFLSQSALTCGHKSSSSFE
HHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLLMIDNYDSFTFNLVQYFQQLGQEIVVKRNDEISLAEIEALAPSHLVISPGPCSPNEAG
CEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHCCCCEEEEECCCCCCCCCC
ISLAAIEHFATRLPILGVCLGHQAMAQVFGAKVVRAQRVMHGKVSAIGHTGERLFKGLNQ
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
PLTVTRYHSLLVDAVPEGFVLDAWFDDPTHGREIMAMSHKQLPLFGVQFHPESILTEQGH
CEEHHHHHHHHHHHCCCCEEEEEECCCCCCCHHEEHHCCCCCCEEEEEECCHHHHHHHHH
ELLANFLSQSALTCGHKSSSSFE
HHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3894673 [H]