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The map label for this gene is aer [H]

Identifier: 113968927

GI number: 113968927

Start: 672707

End: 674281

Strand: Direct

Name: aer [H]

Synonym: Shewmr4_0583

Alternate gene names: 113968927

Gene position: 672707-674281 (Clockwise)

Preceding gene: 113968925

Following gene: 113968929

Centisome position: 14.29

GC content: 51.17

Gene sequence:

>1575_bases
ATGAGAAAAAATTTACCAATAACACAGCGGGAATACGACTATCCAGCGGATTGGATTTTACTGTCGACGACGGACACTAA
GAGTCATATCACTTACGCCAATCCATCATTTTGTACCGTTGCGGGATACGAGCTTAGCGCCATGTTGGGGCAACCCCATA
ATATGGTGCGTCATCCCGATATGCCCCCCGAAGCATTTGAAGATCTGTGGAAAACCATCCGAAAAGGCGAGCCTTGGAAA
GGCATAGTCAAAAATCGCTGTGCCAATGGCGACCATTATTGGGTCGACGCCTATGTGTCGCCGATTATGGTCAATGGTCA
GGTGGCCGAATTTCAATCGGTACGCACTAAACCCAGCCGCGACCAGATAAACCGAGCAGAAGCCGTCTATGCCGAATTAA
ATAAGAGTGGTCAAGTTAAGGCATTAAAACGCACCTTAGAAATGCCGACTCAGTTGATGCTACTCGCCTTAGTTGCTCTG
TTGCCCATGCTGTATTTGGCGCTGCAGATTGGAGCGGTGGGATTTGTCGCGCTTGCCATTAGTGCTCTGGCACTTTTTAT
TGGTGGCAATATGATTTTAGGGCGTTATCGGGCGCTGGTCGCTAAGGCGAAGAAAATCTACAACAACCCTTTGATGGCAC
ATATCTATACCGGAAAATCCGATGATCTAGGCGCGATCGATCTGGCGCTGCAAATGCAAACCTCAGAGTTAAAATCCATG
TTAGGTCGCGCCCGCGATTCCTGCGATAAGGTGAGTAAGCAAGCCAAAGTTTCGGCGGCGAAAGGCGAAGAGATTCAAGG
GACAAGCCAGTCACAGCTGGCCGAGATTGAACAAGTCGCGACGGCCATGCAACAGATGACGGCGACACTTGGGGATATGT
CTTCTAACTGTGCCGATGCGGCGAGCGCTTCACAGATGGCGTCGCAGCAGACAATCAATGGCGATAAAACTGTTGTCAGT
ACCATTCAATCGATTCAGGCCATGGCGCAGCAGTTGCAAGAAACCTCGCAGGTGATCACTGAGTTAGAAGGGCATAGCAG
GGATATAGGCACAGTGCTGGATGTGATCCAGGGGATTGCCGAACAGACAAATTTATTGGCACTAAACGCCGCGATTGAAG
CGGCGCGAGCGGGTGAGCAAGGGCGTGGTTTTGCCGTAGTTGCCGATGAGGTGCGGGCATTAGCGCAGCGAACCCATGAT
GCCACCAAGGAAATCCACACAATGATCAACCTGTTGCAGCAGGGCACCCACAAGGCGGTGCGCAGCATGCAAGAAGGAGT
CGATGCCGCCGCTGAATGTATTACCACTGCGGATCTTGCGGGCACGGCGCTGCGTACCATACGTGAAGCTATCACTACCA
TTACGGATATGACCCACCATATTGCCAGTGCGGTAGAGGAGCAATCGAGCGTGGCGAACGAGATGAATCGCAGCGTGGTC
AATGTGTCGCAATTTACCCATTCCAGCCATCAACTCGGCTGTGAAATGGTCAGCATCAATGATGAGGTGATAGGCGAAAT
GGACTCCCATACAGTGCTGGTCGGGCAGTTTTTAAAGCGCAGCTTTAAGGTATAG

Upstream 100 bases:

>100_bases
AAGAGGGATGATGTAGCAGTAACGTGTCATTGGACGCGAGCAAGGATGGATAACTCATGGATGATGGAATAATAAATTTA
TAATAGATCCAAGGGTTATC

Downstream 100 bases:

>100_bases
AGCGTTGTTGCAGTAAAAACGAAATCAAAAGGCAATCAGCGTGCTGATTGCCTTTTCTTTTTTCTGATCTTAAGGCAGCC
GTGATTAATAGCCCTTAGTA

Product: methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MRKNLPITQREYDYPADWILLSTTDTKSHITYANPSFCTVAGYELSAMLGQPHNMVRHPDMPPEAFEDLWKTIRKGEPWK
GIVKNRCANGDHYWVDAYVSPIMVNGQVAEFQSVRTKPSRDQINRAEAVYAELNKSGQVKALKRTLEMPTQLMLLALVAL
LPMLYLALQIGAVGFVALAISALALFIGGNMILGRYRALVAKAKKIYNNPLMAHIYTGKSDDLGAIDLALQMQTSELKSM
LGRARDSCDKVSKQAKVSAAKGEEIQGTSQSQLAEIEQVATAMQQMTATLGDMSSNCADAASASQMASQQTINGDKTVVS
TIQSIQAMAQQLQETSQVITELEGHSRDIGTVLDVIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHD
ATKEIHTMINLLQQGTHKAVRSMQEGVDAAAECITTADLAGTALRTIREAITTITDMTHHIASAVEEQSSVANEMNRSVV
NVSQFTHSSHQLGCEMVSINDEVIGEMDSHTVLVGQFLKRSFKV

Sequences:

>Translated_524_residues
MRKNLPITQREYDYPADWILLSTTDTKSHITYANPSFCTVAGYELSAMLGQPHNMVRHPDMPPEAFEDLWKTIRKGEPWK
GIVKNRCANGDHYWVDAYVSPIMVNGQVAEFQSVRTKPSRDQINRAEAVYAELNKSGQVKALKRTLEMPTQLMLLALVAL
LPMLYLALQIGAVGFVALAISALALFIGGNMILGRYRALVAKAKKIYNNPLMAHIYTGKSDDLGAIDLALQMQTSELKSM
LGRARDSCDKVSKQAKVSAAKGEEIQGTSQSQLAEIEQVATAMQQMTATLGDMSSNCADAASASQMASQQTINGDKTVVS
TIQSIQAMAQQLQETSQVITELEGHSRDIGTVLDVIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHD
ATKEIHTMINLLQQGTHKAVRSMQEGVDAAAECITTADLAGTALRTIREAITTITDMTHHIASAVEEQSSVANEMNRSVV
NVSQFTHSSHQLGCEMVSINDEVIGEMDSHTVLVGQFLKRSFKV
>Mature_524_residues
MRKNLPITQREYDYPADWILLSTTDTKSHITYANPSFCTVAGYELSAMLGQPHNMVRHPDMPPEAFEDLWKTIRKGEPWK
GIVKNRCANGDHYWVDAYVSPIMVNGQVAEFQSVRTKPSRDQINRAEAVYAELNKSGQVKALKRTLEMPTQLMLLALVAL
LPMLYLALQIGAVGFVALAISALALFIGGNMILGRYRALVAKAKKIYNNPLMAHIYTGKSDDLGAIDLALQMQTSELKSM
LGRARDSCDKVSKQAKVSAAKGEEIQGTSQSQLAEIEQVATAMQQMTATLGDMSSNCADAASASQMASQQTINGDKTVVS
TIQSIQAMAQQLQETSQVITELEGHSRDIGTVLDVIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHD
ATKEIHTMINLLQQGTHKAVRSMQEGVDAAAECITTADLAGTALRTIREAITTITDMTHHIASAVEEQSSVANEMNRSVV
NVSQFTHSSHQLGCEMVSINDEVIGEMDSHTVLVGQFLKRSFKV

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=509, Percent_Identity=32.2200392927308, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI2367378, Length=289, Percent_Identity=31.4878892733564, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI1787690, Length=402, Percent_Identity=27.8606965174129, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788195, Length=302, Percent_Identity=29.4701986754967, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1788194, Length=358, Percent_Identity=31.2849162011173, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 57048; Mature: 57048

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKNLPITQREYDYPADWILLSTTDTKSHITYANPSFCTVAGYELSAMLGQPHNMVRHPD
CCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCEEEEECCHHHHHHCCCHHHCCCCC
MPPEAFEDLWKTIRKGEPWKGIVKNRCANGDHYWVDAYVSPIMVNGQVAEFQSVRTKPSR
CCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEECCCEEECCCHHHHHHHCCCCCH
DQINRAEAVYAELNKSGQVKALKRTLEMPTQLMLLALVALLPMLYLALQIGAVGFVALAI
HHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALALFIGGNMILGRYRALVAKAKKIYNNPLMAHIYTGKSDDLGAIDLALQMQTSELKSM
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
LGRARDSCDKVSKQAKVSAAKGEEIQGTSQSQLAEIEQVATAMQQMTATLGDMSSNCADA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ASASQMASQQTINGDKTVVSTIQSIQAMAQQLQETSQVITELEGHSRDIGTVLDVIQGIA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
EQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHDATKEIHTMINLLQQGTHKAV
HHHHEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSMQEGVDAAAECITTADLAGTALRTIREAITTITDMTHHIASAVEEQSSVANEMNRSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVSQFTHSSHQLGCEMVSINDEVIGEMDSHTVLVGQFLKRSFKV
HHHHHHCCHHHCCCEEEECCHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKNLPITQREYDYPADWILLSTTDTKSHITYANPSFCTVAGYELSAMLGQPHNMVRHPD
CCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCEEEEECCHHHHHHCCCHHHCCCCC
MPPEAFEDLWKTIRKGEPWKGIVKNRCANGDHYWVDAYVSPIMVNGQVAEFQSVRTKPSR
CCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEECCCEEECCCHHHHHHHCCCCCH
DQINRAEAVYAELNKSGQVKALKRTLEMPTQLMLLALVALLPMLYLALQIGAVGFVALAI
HHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALALFIGGNMILGRYRALVAKAKKIYNNPLMAHIYTGKSDDLGAIDLALQMQTSELKSM
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
LGRARDSCDKVSKQAKVSAAKGEEIQGTSQSQLAEIEQVATAMQQMTATLGDMSSNCADA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ASASQMASQQTINGDKTVVSTIQSIQAMAQQLQETSQVITELEGHSRDIGTVLDVIQGIA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
EQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHDATKEIHTMINLLQQGTHKAV
HHHHEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSMQEGVDAAAECITTADLAGTALRTIREAITTITDMTHHIASAVEEQSSVANEMNRSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVSQFTHSSHQLGCEMVSINDEVIGEMDSHTVLVGQFLKRSFKV
HHHHHHCCHHHCCCEEEECCHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]