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The map label for this gene is caiD [C]

Identifier: 113968917

GI number: 113968917

Start: 655625

End: 656431

Strand: Direct

Name: caiD [C]

Synonym: Shewmr4_0573

Alternate gene names: 113968917

Gene position: 655625-656431 (Clockwise)

Preceding gene: 113968914

Following gene: 113968920

Centisome position: 13.93

GC content: 49.94

Gene sequence:

>807_bases
ATGAGTGAGCCTTGCGTGCAAGTAACGATTGAGAATGGCATTGCATATGTCCAGCTCAATCGACCAGAAAAATATAATGC
AATTAACTATTTAATGTTTAGCGAGTTGGATAGAGCGATCAAACGTATTAAATCAAATTCGCAGATTCGACTGGTTATTT
TATCTGGAGCCGGAGGCCATTTTAGCTCGGGGCTGGACGTAAAGAGCGTGATGTCGGCACCGATGCAAGCATTCAAATTG
CTGTTTAAATGGTTGCCTGGCAATGCCAACTTAGCGCAGAGAGTCTCCCTTGGTTGGCAACGTTTACCCGTGCCCGTCAT
CGCGGTGTTAGAAGGCTGCTGCTATGGCGGTGGCATGCAAATCGCATTAGGTGCTGATTTTAGAATAGCGAGCCCTGACA
GCAAGTTATCTATTATGGAAGCCAAATGGGGGCTCGTGCCGGACATGGCAGGCTTAGTGGCGCTGAGGCAAATAATGCCC
AAGGATCAGGCGATGTTACTCAGCCTTACGGCCAAAGTGTTGTCGGGCGAAGAGGCGAGTCGCTTAGGGTTAGTGACTCA
GCTAAGTGATCATCCGATGTTAAGCGCGCAGCAATTGGCTCAGGAACTTCTCAATACTTCCCCCGATGCCGCAGCGGCGA
TCAAGTTGAGCATCAATCGCAGCTGGACGGCTTCGATTCGTGCACTTCTTTGCCGTGAGTCGTGGAGCCAAGTGAGACTG
TTACTCGGTAAAAATCGCGCGATTGCAGCGACGCGTCAGCTAAAGGATCCCAACAAAGCCTATCAAGATCGCCAATCGGG
TTGGTAG

Upstream 100 bases:

>100_bases
TTTTGACGCATGTCAAAATTTAGGCTTATGTTACATCCTTTGGTGAATTATTCCAAACGTGTTAACATTTGTTCTGGCCT
GACCAGTAACGGAATATTTC

Downstream 100 bases:

>100_bases
CAGTGCAATTCTATCTCGATAACGCCCCATAACGGATGACTTAAGCTTTAGAAAGGCTTGCACCTCAATGGGCGCCGCTC
ATACGGGCGGCGAATCCCCT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSEPCVQVTIENGIAYVQLNRPEKYNAINYLMFSELDRAIKRIKSNSQIRLVILSGAGGHFSSGLDVKSVMSAPMQAFKL
LFKWLPGNANLAQRVSLGWQRLPVPVIAVLEGCCYGGGMQIALGADFRIASPDSKLSIMEAKWGLVPDMAGLVALRQIMP
KDQAMLLSLTAKVLSGEEASRLGLVTQLSDHPMLSAQQLAQELLNTSPDAAAAIKLSINRSWTASIRALLCRESWSQVRL
LLGKNRAIAATRQLKDPNKAYQDRQSGW

Sequences:

>Translated_268_residues
MSEPCVQVTIENGIAYVQLNRPEKYNAINYLMFSELDRAIKRIKSNSQIRLVILSGAGGHFSSGLDVKSVMSAPMQAFKL
LFKWLPGNANLAQRVSLGWQRLPVPVIAVLEGCCYGGGMQIALGADFRIASPDSKLSIMEAKWGLVPDMAGLVALRQIMP
KDQAMLLSLTAKVLSGEEASRLGLVTQLSDHPMLSAQQLAQELLNTSPDAAAAIKLSINRSWTASIRALLCRESWSQVRL
LLGKNRAIAATRQLKDPNKAYQDRQSGW
>Mature_267_residues
SEPCVQVTIENGIAYVQLNRPEKYNAINYLMFSELDRAIKRIKSNSQIRLVILSGAGGHFSSGLDVKSVMSAPMQAFKLL
FKWLPGNANLAQRVSLGWQRLPVPVIAVLEGCCYGGGMQIALGADFRIASPDSKLSIMEAKWGLVPDMAGLVALRQIMPK
DQAMLLSLTAKVLSGEEASRLGLVTQLSDHPMLSAQQLAQELLNTSPDAAAAIKLSINRSWTASIRALLCRESWSQVRLL
LGKNRAIAATRQLKDPNKAYQDRQSGW

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=256, Percent_Identity=28.90625, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI157694516, Length=240, Percent_Identity=26.6666666666667, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI213417737, Length=240, Percent_Identity=26.6666666666667, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI194097323, Length=220, Percent_Identity=26.8181818181818, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI68989263, Length=195, Percent_Identity=26.1538461538462, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI260274832, Length=181, Percent_Identity=29.8342541436464, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI45643119, Length=181, Percent_Identity=29.8342541436464, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI260275230, Length=181, Percent_Identity=29.8342541436464, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI20127408, Length=183, Percent_Identity=27.8688524590164, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI37594471, Length=189, Percent_Identity=27.5132275132275, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4502327, Length=245, Percent_Identity=28.1632653061224, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI37594469, Length=189, Percent_Identity=27.5132275132275, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI157694520, Length=220, Percent_Identity=25.9090909090909, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI31542718, Length=178, Percent_Identity=26.4044943820225, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI221142681, Length=221, Percent_Identity=33.9366515837104, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787660, Length=224, Percent_Identity=32.1428571428571, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790281, Length=176, Percent_Identity=27.8409090909091, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788682, Length=198, Percent_Identity=28.7878787878788, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787659, Length=260, Percent_Identity=25.3846153846154, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082183, Length=219, Percent_Identity=23.2876712328767, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17540714, Length=250, Percent_Identity=29.2, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17536985, Length=210, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17560910, Length=175, Percent_Identity=27.4285714285714, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17558304, Length=296, Percent_Identity=26.0135135135135, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI25145438, Length=256, Percent_Identity=24.21875, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=264, Percent_Identity=22.3484848484848, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25141363, Length=214, Percent_Identity=26.1682242990654, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=250, Percent_Identity=26.8, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508951, Length=250, Percent_Identity=26.8, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=250, Percent_Identity=26.8, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=204, Percent_Identity=26.9607843137255, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24653139, Length=254, Percent_Identity=28.3464566929134, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920382, Length=215, Percent_Identity=24.6511627906977, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19922422, Length=251, Percent_Identity=25.8964143426295, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129971, Length=220, Percent_Identity=24.0909090909091, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24653477, Length=220, Percent_Identity=24.0909090909091, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357171, Length=181, Percent_Identity=24.8618784530387, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19921000, Length=230, Percent_Identity=28.695652173913, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583077, Length=230, Percent_Identity=28.695652173913, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583079, Length=230, Percent_Identity=28.695652173913, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571729, Length=194, Percent_Identity=28.8659793814433, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571730, Length=194, Percent_Identity=28.8659793814433, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29335; Mature: 29203

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPCVQVTIENGIAYVQLNRPEKYNAINYLMFSELDRAIKRIKSNSQIRLVILSGAGGH
CCCCEEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
FSSGLDVKSVMSAPMQAFKLLFKWLPGNANLAQRVSLGWQRLPVPVIAVLEGCCYGGGMQ
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHCCHHHHHHHHHHCCCCCEE
IALGADFRIASPDSKLSIMEAKWGLVPDMAGLVALRQIMPKDQAMLLSLTAKVLSGEEAS
EEECCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHH
RLGLVTQLSDHPMLSAQQLAQELLNTSPDAAAAIKLSINRSWTASIRALLCRESWSQVRL
HHHHHEECCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
LLGKNRAIAATRQLKDPNKAYQDRQSGW
HHCCCCCEEHHHHCCCCHHHHHHHCCCC
>Mature Secondary Structure 
SEPCVQVTIENGIAYVQLNRPEKYNAINYLMFSELDRAIKRIKSNSQIRLVILSGAGGH
CCCEEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
FSSGLDVKSVMSAPMQAFKLLFKWLPGNANLAQRVSLGWQRLPVPVIAVLEGCCYGGGMQ
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHCCHHHHHHHHHHCCCCCEE
IALGADFRIASPDSKLSIMEAKWGLVPDMAGLVALRQIMPKDQAMLLSLTAKVLSGEEAS
EEECCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHH
RLGLVTQLSDHPMLSAQQLAQELLNTSPDAAAAIKLSINRSWTASIRALLCRESWSQVRL
HHHHHEECCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
LLGKNRAIAATRQLKDPNKAYQDRQSGW
HHCCCCCEEHHHHCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA