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The map label for this gene is gap3 [H]

Identifier: 113968880

GI number: 113968880

Start: 619186

End: 620199

Strand: Direct

Name: gap3 [H]

Synonym: Shewmr4_0536

Alternate gene names: 113968880

Gene position: 619186-620199 (Clockwise)

Preceding gene: 113968879

Following gene: 113968881

Centisome position: 13.16

GC content: 51.68

Gene sequence:

>1014_bases
ATGGCAATCAAAATTGGCATTAATGGTTTCGGGCGTATGGGGCGTTTAGCCCTGCGTGCGGCGTGGGAATGGGATGATGT
TGAGTTTGTGCAGATTAATGATCCTGCTGGGGATGCGGCTACCTTGGCCCATTTGCTTGAGTTCGATTCAGTCCATGGTC
GCTGGCGTTATCCGGTAACGGCGAGTCACGATGGCATTCAAATTCAAGATAAAACCATTCACACTACAGGCAATAAAACG
ATTGCTGAGACCGATTGGTCGGGATGCGATGTGGTGATTGAAGCCTCCGGCGTGATGAAAACCAAAGCCTTGCTACAAGC
CTATTTAGATCAAGGCGTTAAGCGGGTGGTTGTGACCGCACCTGTGAAAGAAGAGGGGGTGTTAAATGTGGTGATGGGCG
TGAACCATCAGCTATACGATCCTACTATCCACCCAATCGTCACTGCCGCATCTTGTACTACCAACTGCCTTGCGCCTGTG
GTGAAAGTGATCCATGAGCAGATCGGCATTAGGCATGGTTCCATGACGACCATCCACGATATTACCAATACCCAGACGAT
TCTCGATGCGCCCCATAAGGATTTACGCCGTGCCCGCGCCTGTGGTTTGAGTTTAATCCCCACCACCACCGGCAGTGCGA
CGGCAATTACCCATATTTTCCCAGAGCTTAAGGGCAAGTTGAATGGCCATGCCGTACGGGTGCCGCTCGCTAATGCGTCC
CTTACCGACTGTGTATTTGAGCTTGAGCGCAGAGTGACTGAAGCAGAAGTGAATGCGTTGCTACAAAGCGCCGCCGAAGG
TGAGCTTAAGGGTATTTTAGGTTATGAGGAGCGGCCGTTAGTGTCGGTTGATTATAAAACCGATCCCCGTTCGAGCATTG
TCGATGCGCTTTCGACCATGGTGGTGAATGGGACTCAGCTAAAACTCTACGTGTGGTACGACAATGAGTGGGGATATGCC
AACCGTACGGCAGAGCTCGCCCGTTTAGTCGGCCAGCTTGATATGCCGCGTTAG

Upstream 100 bases:

>100_bases
GCAATGGTGGTGTTACCGCTTAAGTAACCTATTAGTAGTATTCAGAAAATATAATAATTAGCGACATTAAAATTTTAAAT
TAACTTATTGGAATATCAGC

Downstream 100 bases:

>100_bases
GAGACCATAGTGCCTGCTGCCAAGCTATTTGAACAACTGATGCAATTGCCCGCGGCCGTGCGGCAATATTTGCTGATCAC
CTTCAATTACTGGAGTTTTA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MAIKIGINGFGRMGRLALRAAWEWDDVEFVQINDPAGDAATLAHLLEFDSVHGRWRYPVTASHDGIQIQDKTIHTTGNKT
IAETDWSGCDVVIEASGVMKTKALLQAYLDQGVKRVVVTAPVKEEGVLNVVMGVNHQLYDPTIHPIVTAASCTTNCLAPV
VKVIHEQIGIRHGSMTTIHDITNTQTILDAPHKDLRRARACGLSLIPTTTGSATAITHIFPELKGKLNGHAVRVPLANAS
LTDCVFELERRVTEAEVNALLQSAAEGELKGILGYEERPLVSVDYKTDPRSSIVDALSTMVVNGTQLKLYVWYDNEWGYA
NRTAELARLVGQLDMPR

Sequences:

>Translated_337_residues
MAIKIGINGFGRMGRLALRAAWEWDDVEFVQINDPAGDAATLAHLLEFDSVHGRWRYPVTASHDGIQIQDKTIHTTGNKT
IAETDWSGCDVVIEASGVMKTKALLQAYLDQGVKRVVVTAPVKEEGVLNVVMGVNHQLYDPTIHPIVTAASCTTNCLAPV
VKVIHEQIGIRHGSMTTIHDITNTQTILDAPHKDLRRARACGLSLIPTTTGSATAITHIFPELKGKLNGHAVRVPLANAS
LTDCVFELERRVTEAEVNALLQSAAEGELKGILGYEERPLVSVDYKTDPRSSIVDALSTMVVNGTQLKLYVWYDNEWGYA
NRTAELARLVGQLDMPR
>Mature_336_residues
AIKIGINGFGRMGRLALRAAWEWDDVEFVQINDPAGDAATLAHLLEFDSVHGRWRYPVTASHDGIQIQDKTIHTTGNKTI
AETDWSGCDVVIEASGVMKTKALLQAYLDQGVKRVVVTAPVKEEGVLNVVMGVNHQLYDPTIHPIVTAASCTTNCLAPVV
KVIHEQIGIRHGSMTTIHDITNTQTILDAPHKDLRRARACGLSLIPTTTGSATAITHIFPELKGKLNGHAVRVPLANASL
TDCVFELERRVTEAEVNALLQSAAEGELKGILGYEERPLVSVDYKTDPRSSIVDALSTMVVNGTQLKLYVWYDNEWGYAN
RTAELARLVGQLDMPR

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=327, Percent_Identity=41.8960244648318, Blast_Score=265, Evalue=3e-71,
Organism=Homo sapiens, GI7657116, Length=335, Percent_Identity=39.4029850746269, Blast_Score=244, Evalue=1e-64,
Organism=Escherichia coli, GI1788079, Length=329, Percent_Identity=42.5531914893617, Blast_Score=261, Evalue=3e-71,
Organism=Escherichia coli, GI1789295, Length=327, Percent_Identity=40.6727828746177, Blast_Score=245, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17534677, Length=330, Percent_Identity=41.8181818181818, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17534679, Length=330, Percent_Identity=41.2121212121212, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI32566163, Length=332, Percent_Identity=41.8674698795181, Blast_Score=261, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17568413, Length=332, Percent_Identity=41.8674698795181, Blast_Score=261, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=41.4414414414414, Blast_Score=261, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6321631, Length=333, Percent_Identity=41.1411411411411, Blast_Score=259, Evalue=4e-70,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=40.5405405405405, Blast_Score=258, Evalue=1e-69,
Organism=Drosophila melanogaster, GI17933600, Length=334, Percent_Identity=39.8203592814371, Blast_Score=246, Evalue=1e-65,
Organism=Drosophila melanogaster, GI18110149, Length=334, Percent_Identity=39.8203592814371, Blast_Score=246, Evalue=1e-65,
Organism=Drosophila melanogaster, GI19922412, Length=336, Percent_Identity=39.2857142857143, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI85725000, Length=334, Percent_Identity=39.8203592814371, Blast_Score=245, Evalue=3e-65,
Organism=Drosophila melanogaster, GI22023983, Length=334, Percent_Identity=39.8203592814371, Blast_Score=245, Evalue=3e-65,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36866; Mature: 36734

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKIGINGFGRMGRLALRAAWEWDDVEFVQINDPAGDAATLAHLLEFDSVHGRWRYPVT
CEEEEECCCCCCHHHHHEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEECCEE
ASHDGIQIQDKTIHTTGNKTIAETDWSGCDVVIEASGVMKTKALLQAYLDQGVKRVVVTA
CCCCCEEEECCEEEECCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEC
PVKEEGVLNVVMGVNHQLYDPTIHPIVTAASCTTNCLAPVVKVIHEQIGIRHGSMTTIHD
CCCCCCCEEEEECCCCEECCCCHHHHEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ITNTQTILDAPHKDLRRARACGLSLIPTTTGSATAITHIFPELKGKLNGHAVRVPLANAS
CCCCHHHHCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCH
LTDCVFELERRVTEAEVNALLQSAAEGELKGILGYEERPLVSVDYKTDPRSSIVDALSTM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEECCCCCHHHHHHHHHHH
VVNGTQLKLYVWYDNEWGYANRTAELARLVGQLDMPR
EECCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AIKIGINGFGRMGRLALRAAWEWDDVEFVQINDPAGDAATLAHLLEFDSVHGRWRYPVT
EEEEECCCCCCHHHHHEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEECCEE
ASHDGIQIQDKTIHTTGNKTIAETDWSGCDVVIEASGVMKTKALLQAYLDQGVKRVVVTA
CCCCCEEEECCEEEECCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEC
PVKEEGVLNVVMGVNHQLYDPTIHPIVTAASCTTNCLAPVVKVIHEQIGIRHGSMTTIHD
CCCCCCCEEEEECCCCEECCCCHHHHEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ITNTQTILDAPHKDLRRARACGLSLIPTTTGSATAITHIFPELKGKLNGHAVRVPLANAS
CCCCHHHHCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCH
LTDCVFELERRVTEAEVNALLQSAAEGELKGILGYEERPLVSVDYKTDPRSSIVDALSTM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEECCCCCHHHHHHHHHHH
VVNGTQLKLYVWYDNEWGYANRTAELARLVGQLDMPR
EECCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]