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The map label for this gene is ubiA [H]

Identifier: 113968818

GI number: 113968818

Start: 539931

End: 540791

Strand: Direct

Name: ubiA [H]

Synonym: Shewmr4_0474

Alternate gene names: 113968818

Gene position: 539931-540791 (Clockwise)

Preceding gene: 113968817

Following gene: 113968820

Centisome position: 11.47

GC content: 49.25

Gene sequence:

>861_bases
ATGAATCTAAAGCAGAAGTGGGACGTGTATTCCCGCCTGACTCGACTCGACCGTCCTATCGGCACCTTGTTATTGCTCTG
GCCCTGTTTAATGGCGCTGGTGTTAGCGGCGGGTGGAATGCCCGATATCAAAGTGTTGATTATCTTTATTATCGGTGTGG
TGATCATGCGTGCCTGTGGCTGCATTATTAACGACTATGCCGACCGCGACCTCGACTCCCACGTTGAACGCACTAGATCC
CGTCCCCTCGCCAGTGGCGAAATCAGCACCAAAGAAGCGTTATTGCTGTTTGTGATCTTAGGTCTAGCCGCCTTTGGTTT
AGTCTTACTGCTCAATGGTTTAGTGGTTAAGCTCTCTGTTGTCGGCATTATCCTCACCATTATCTACCCCTTTACTAAGC
GGGTAACGAATATGCCGCAGATGTTTTTGGGCGTGGTGTGGAGTTGGTCGATTCCCATGGCTTATGCGGCGCAAACCGGT
GAAGTGCCCATCGAAGCTTGGTGGTTATTTGCCGCCAATTGGTTTTGGACTGTGGCCTACGACACTATGTACGCCATGGT
CGATAGGGACGATGATTTAAAAGTCGGTATCAAATCGACCGCCATTCTGTTTGGCCAATACGATCGCCAAATCATTGGAT
TATTTCAATTTGCTGCGCTGCTGTGTTTTATCGCAGCGGGTTGGAGTGCCGACCGTGGCCTGCTCTATGGTCTGGGACTA
CTTACCTTTGTTGGTTTTAGCACTTACCAACAGATGTTGATTTTTGGCCGCGAGAGAGCTCCTTGCTTTAAAGCCTTCCT
TAACAATAACTGGGCAGGGTTAGCACTGTTTGTTGGTTTAGGCGCCGATTACCTGTTCTAA

Upstream 100 bases:

>100_bases
ACAGCTTGAGTCTGCACAAATTCGCTTAAAAGGTGGCTAGGGTATATGATGCTTAGCCTAGCAACCGAGATAAAAAATTA
GGTTTGGGAGTAGCTAGTTA

Downstream 100 bases:

>100_bases
ACATTTTCGAGTAAATTTAAGTTTATTTGTGCGCGTTAGAATAACCTAACGCGCACATTAAAGGATATTTACGACTTCCA
GACGTCATTATTCTTGTATC

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MNLKQKWDVYSRLTRLDRPIGTLLLLWPCLMALVLAAGGMPDIKVLIIFIIGVVIMRACGCIINDYADRDLDSHVERTRS
RPLASGEISTKEALLLFVILGLAAFGLVLLLNGLVVKLSVVGIILTIIYPFTKRVTNMPQMFLGVVWSWSIPMAYAAQTG
EVPIEAWWLFAANWFWTVAYDTMYAMVDRDDDLKVGIKSTAILFGQYDRQIIGLFQFAALLCFIAAGWSADRGLLYGLGL
LTFVGFSTYQQMLIFGRERAPCFKAFLNNNWAGLALFVGLGADYLF

Sequences:

>Translated_286_residues
MNLKQKWDVYSRLTRLDRPIGTLLLLWPCLMALVLAAGGMPDIKVLIIFIIGVVIMRACGCIINDYADRDLDSHVERTRS
RPLASGEISTKEALLLFVILGLAAFGLVLLLNGLVVKLSVVGIILTIIYPFTKRVTNMPQMFLGVVWSWSIPMAYAAQTG
EVPIEAWWLFAANWFWTVAYDTMYAMVDRDDDLKVGIKSTAILFGQYDRQIIGLFQFAALLCFIAAGWSADRGLLYGLGL
LTFVGFSTYQQMLIFGRERAPCFKAFLNNNWAGLALFVGLGADYLF
>Mature_286_residues
MNLKQKWDVYSRLTRLDRPIGTLLLLWPCLMALVLAAGGMPDIKVLIIFIIGVVIMRACGCIINDYADRDLDSHVERTRS
RPLASGEISTKEALLLFVILGLAAFGLVLLLNGLVVKLSVVGIILTIIYPFTKRVTNMPQMFLGVVWSWSIPMAYAAQTG
EVPIEAWWLFAANWFWTVAYDTMYAMVDRDDDLKVGIKSTAILFGQYDRQIIGLFQFAALLCFIAAGWSADRGLLYGLGL
LTFVGFSTYQQMLIFGRERAPCFKAFLNNNWAGLALFVGLGADYLF

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=277, Percent_Identity=36.101083032491, Blast_Score=156, Evalue=2e-38,
Organism=Escherichia coli, GI1790473, Length=281, Percent_Identity=52.3131672597865, Blast_Score=281, Evalue=3e-77,
Organism=Escherichia coli, GI1786631, Length=161, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17553718, Length=280, Percent_Identity=35, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI32565247, Length=286, Percent_Identity=34.2657342657343, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17553720, Length=347, Percent_Identity=28.2420749279539, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI32565245, Length=145, Percent_Identity=42.0689655172414, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI32565243, Length=136, Percent_Identity=41.9117647058824, Blast_Score=101, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6324370, Length=297, Percent_Identity=31.3131313131313, Blast_Score=139, Evalue=4e-34,
Organism=Drosophila melanogaster, GI21355567, Length=276, Percent_Identity=40.9420289855072, Blast_Score=184, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 31961; Mature: 31961

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHCCHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA