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The map label for this gene is pip [H]

Identifier: 113968661

GI number: 113968661

Start: 344065

End: 345021

Strand: Direct

Name: pip [H]

Synonym: Shewmr4_0317

Alternate gene names: 113968661

Gene position: 344065-345021 (Clockwise)

Preceding gene: 113968660

Following gene: 113968662

Centisome position: 7.31

GC content: 49.11

Gene sequence:

>957_bases
ATGATCACTGACGCCCATCAGCTTGCCCCTTTTATCCGCCGTGATTGGCTGATGATGGGCAATGGGCAGCAGTTGCATCT
CGCTCAATATGGTAATCCGCGGGGGATTCCGCTGCTGTATTTGCATGGTGGTCCAGGAGCGGGGGCTTCGGTCAGTGAAC
TGAGTTTATTTAACCCCGAGCACTATTGGATTTTACTTTTAGATCAACGTGGTGCGGGACAATCACTGCCAGCTGGCGAG
TTGGAACATAACCATTTAAATGGGCTTATCTGTGATATTGAGGCGATTCGTATTCACTTAGGCATAGAGCGTTGGTGCCT
AGCGGGTGGCTCATTTGGCGCCACCTTAGCCTTAATTTACAGTGGCTTATTTCCCCATCGAGTGATTGCCCAAGTGCTGT
GGGCAATGTTTATTCCCTCCAAGGCCGGCATTGAATGGCTCTATGCACCCTCGGGCGCGGCGCAGTTATATTCGCAGGCT
TACCGTGAATTTGCTGCACCTTCTATTGGATTGGCGGATTTATTTACGCACTATCAGCTAGGATTGAACGCCCAAGATGA
AGTAATTCGTCATGAATTTGCCCGCCGTTGGATCCAATGGGAATTAATCTTAGCGGGCGTACCAACTGGCCTACCTAAGC
GGCTTACAACGCCGTTATTGGCCTTAGCTCAAATCGAGCTGCACTATGCAAAAAATGATTACTTCAATATGTTCAGCGTA
TTACAACGGGTGACATCTCAAGTCACAGCGCGTACCCTGCTATTACAAGGCACGCAGGATGCTGTCTGTCCGGCACGCTT
ATTAGCCGCATTTTTGGCAAAAATCGACAACCCTAGGATACAAATTCATACCATTGTCGATGGTGGGCATTCGCTGAATA
GTGACATACTCTCACTTGCCGTCACACTCGAGATCCAAGCCATGTGGACTTGGATAAAGCGACAGGAGCTAGCATGA

Upstream 100 bases:

>100_bases
GACAGGCGAACTCGCTGCAACCGCGCCGCAATCGACTACACTGGATAAGCCGTAGCTAAGTTGTTATCCACCAAGACATT
CAGCGAGCCTTATCCCATCT

Downstream 100 bases:

>100_bases
AATTAGCCGTTATCATTGCCGCCATTTTGGGATTAACAGCCTGCGCGGCCACCTCATCCTCTACCCCAGAATCTCAATCC
TCATCTTCTGCGGTCGAATC

Product: prolyl aminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MITDAHQLAPFIRRDWLMMGNGQQLHLAQYGNPRGIPLLYLHGGPGAGASVSELSLFNPEHYWILLLDQRGAGQSLPAGE
LEHNHLNGLICDIEAIRIHLGIERWCLAGGSFGATLALIYSGLFPHRVIAQVLWAMFIPSKAGIEWLYAPSGAAQLYSQA
YREFAAPSIGLADLFTHYQLGLNAQDEVIRHEFARRWIQWELILAGVPTGLPKRLTTPLLALAQIELHYAKNDYFNMFSV
LQRVTSQVTARTLLLQGTQDAVCPARLLAAFLAKIDNPRIQIHTIVDGGHSLNSDILSLAVTLEIQAMWTWIKRQELA

Sequences:

>Translated_318_residues
MITDAHQLAPFIRRDWLMMGNGQQLHLAQYGNPRGIPLLYLHGGPGAGASVSELSLFNPEHYWILLLDQRGAGQSLPAGE
LEHNHLNGLICDIEAIRIHLGIERWCLAGGSFGATLALIYSGLFPHRVIAQVLWAMFIPSKAGIEWLYAPSGAAQLYSQA
YREFAAPSIGLADLFTHYQLGLNAQDEVIRHEFARRWIQWELILAGVPTGLPKRLTTPLLALAQIELHYAKNDYFNMFSV
LQRVTSQVTARTLLLQGTQDAVCPARLLAAFLAKIDNPRIQIHTIVDGGHSLNSDILSLAVTLEIQAMWTWIKRQELA
>Mature_318_residues
MITDAHQLAPFIRRDWLMMGNGQQLHLAQYGNPRGIPLLYLHGGPGAGASVSELSLFNPEHYWILLLDQRGAGQSLPAGE
LEHNHLNGLICDIEAIRIHLGIERWCLAGGSFGATLALIYSGLFPHRVIAQVLWAMFIPSKAGIEWLYAPSGAAQLYSQA
YREFAAPSIGLADLFTHYQLGLNAQDEVIRHEFARRWIQWELILAGVPTGLPKRLTTPLLALAQIELHYAKNDYFNMFSV
LQRVTSQVTARTLLLQGTQDAVCPARLLAAFLAKIDNPRIQIHTIVDGGHSLNSDILSLAVTLEIQAMWTWIKRQELA

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 35368; Mature: 35368

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITDAHQLAPFIRRDWLMMGNGQQLHLAQYGNPRGIPLLYLHGGPGAGASVSELSLFNPE
CCCCHHHHHHHHHHCEEEECCCCEEEEEECCCCCCCEEEEEECCCCCCCCHHHHEEECCC
HYWILLLDQRGAGQSLPAGELEHNHLNGLICDIEAIRIHLGIERWCLAGGSFGATLALIY
EEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEECHHHHHCCCCCHHHHHHHHH
SGLFPHRVIAQVLWAMFIPSKAGIEWLYAPSGAAQLYSQAYREFAAPSIGLADLFTHYQL
HCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHC
GLNAQDEVIRHEFARRWIQWELILAGVPTGLPKRLTTPLLALAQIELHYAKNDYFNMFSV
CCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHEEECCCHHHHHHHH
LQRVTSQVTARTLLLQGTQDAVCPARLLAAFLAKIDNPRIQIHTIVDGGHSLNSDILSLA
HHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHEEEE
VTLEIQAMWTWIKRQELA
EEEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MITDAHQLAPFIRRDWLMMGNGQQLHLAQYGNPRGIPLLYLHGGPGAGASVSELSLFNPE
CCCCHHHHHHHHHHCEEEECCCCEEEEEECCCCCCCEEEEEECCCCCCCCHHHHEEECCC
HYWILLLDQRGAGQSLPAGELEHNHLNGLICDIEAIRIHLGIERWCLAGGSFGATLALIY
EEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEECHHHHHCCCCCHHHHHHHHH
SGLFPHRVIAQVLWAMFIPSKAGIEWLYAPSGAAQLYSQAYREFAAPSIGLADLFTHYQL
HCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHC
GLNAQDEVIRHEFARRWIQWELILAGVPTGLPKRLTTPLLALAQIELHYAKNDYFNMFSV
CCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHEEECCCHHHHHHHH
LQRVTSQVTARTLLLQGTQDAVCPARLLAAFLAKIDNPRIQIHTIVDGGHSLNSDILSLA
HHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHEEEE
VTLEIQAMWTWIKRQELA
EEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]