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The map label for this gene is ptrB [H]

Identifier: 113968481

GI number: 113968481

Start: 153435

End: 155570

Strand: Direct

Name: ptrB [H]

Synonym: Shewmr4_0136

Alternate gene names: 113968481

Gene position: 153435-155570 (Clockwise)

Preceding gene: 113968478

Following gene: 113968482

Centisome position: 3.26

GC content: 50.94

Gene sequence:

>2136_bases
ATGCGCACTCTGCTGCTTACTTTAGGTCTCGCTATGCTATTACCCGGTTGCTCCACTCCAAAAGGGCAAGTCTCTGCGCC
CGTTGCGGAAAAAATTCCCCATGTGATGACCTTGCACGGGGTCACGCGCACCGACGATTACTACTGGATGCGCGACGATA
AACGCCAAGATCCTAAGGTCTTGGCGCATCTGAATGCCGAAAATCGTTACACCCAAGCCTACTTTAAGCCGCTTAAGTCA
TTACAGGATGGGTTGTTTAACGAACTGACTGGGCGCTTAGTGGCCGACGAGTCGAGCGTGCCTTACCAATGGCACCAGCA
CAGCTATTACCGCCGCTACCAAGAGGGCGGCGAATATCCGCTGATCGCCCGCAAAGGCAGTGACGGGATTGAGCAAATGA
TGCTGGACGTGAATGAGCGCGCTAAGGGCCATGAGTTTTATGGTTTAGGTGGCGTCAGCGTCAGCCCGGATGAAACCATG
TTGGCCTTCGGTGAGGATGTCTTAAGCCGCCGCGTGTATAACATCTACTTTAAAGATATTGAGTCCGGCGCCATGATCAC
CGATGTGCTTGAAAACACAGAGGGACGCATCGTTTGGGGCAATGACAATCGCCATGTGTTTTATATCGCCAAAGATCTGC
AAACCCTGCTGGGTTACCGCGTGTATCGCCACGAACTCGGCACGCCACAATCGCGCGATGTGTTGGTGTATGAGGAGCAA
GACGATGCTTACTACATCTCCCTCGGCAAGAGTTTAGACGAGTCGCAAATTGTGCTGTTCCACGAGAGCACCACAACCAG
CGAAGTGTCTGTGCTGGATGCTAACGATCCCCTAAGCCTGTTCAAACCTGTGCTGGCGCGGGAAGAAGGCCATGAATACA
GCGTCTCGAAACTGGGCGACAGCTATTACATTCTCACCAACTGGCAGGCGACTAACTTCCGTTTGATGAAAGTGGCGATT
AAGGATGCCGCCGATAAGTCCAAATGGCAGGAAGTGGTTGCCCATAATCCCAATGCGCGCATCGAAGACGAGCTGGTGCT
AAAGGATTACCTGATTATTCAAACCCGTGAAAATGGTCTGACACGCATTAAAGTGATGCCATTCAATGGTCAAAAGCCCT
TTGAGCTGAGTTTTGACGAGCCCGCCTATGTGCTCGGTTTAGATGTTAACGCCCAGCAAGATAGCGATAAGTTACGGATT
TTCTACTCGAGCCTGACTACGCCCGAGGCGATTTATGAGTACCACTTAAGCAATCCCGATAGACGCGATCTGCTTAAGCA
GGAGCAAGTGCTCGGCGGCTTCGATGCCAGCCAATACCGCGCCGAACGTTTATTTGTCACCGCCCGCGATGGCGCTAAGG
TGCCAGTGTCCTTGGTGTATCGTAAGGATAAGTTCAACAAAGACGGCACCAACCCTCTGTACCAATATGGTTATGGTTCA
TATGGTTACACAGTAGAGCCTGACTTTTCGTCGTCGGTTATCAGTTTGCTCGACCGCGGCTTTGTATATGCCATCGCCCA
TGTGCGCGGCAGCGAAATGTTAGGTCGCCCTTGGTACGATGCGGGTAAGTTGCTGAATAAAAAGAATACCTTTAATGACT
TTATCGATGTCACCACCGCCTTAACCGAGCAAGGTTATGGCGATAAAAATAAAGTGGTGGCCTCGGGCGGCAGTGCTGGC
GGGCTGTTAATGGGCGCGATTGCCAATATGGCGCCTGAAAAGTACTTTGCCATTGCAGCACATGTGCCCTTTGTGGATGT
GGTCACGACCATGCTCGATGAGTCAATTCCGCTCACCACCAACGAGTACGATGAATGGGGTAATCCAAACGAGAAAACCT
ATTTCGACTATATGCTCAGCTACTCGCCCTACGACAATGTTGCCGACCATGAGTACCCACACCTGTTGGTCACCACAGGT
TTGCATGATTCGCAGGTGCAGTATTTCGAGCCAGCTAAATGGGTAGCAAAACTGCGTGAAGTGCAAAATAAATGGTACAA
ACTGGACGATAAGGTGTTGTTATTCGACGTTAATATGGATGCTGGACACGGTGGTAAGAGTGGCCGTTACCGCCAGTATC
AAGACACAGCGCAGGAATATGCCTTCTTCTTAAGCCTGCTCGGCATGACTAAGTAG

Upstream 100 bases:

>100_bases
CGCAACAAGCGCTAGCTTGGGTATATCATATCCGGCACATTAACTTATTGGCTTGCCGTCGTGCCCCACGATGGTGTTTG
AACGTCACAAGGACGTATAA

Downstream 100 bases:

>100_bases
GCGCCAACGGGTGACCGATTTAGTGATTGAAGCCGCTAATTCAACTCCCTCGGCTAGCCCCCAAAAAGGGGCTAGCCAAG
CGCCAGCTGTTAACCAAACT

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 711; Mature: 711

Protein sequence:

>711_residues
MRTLLLTLGLAMLLPGCSTPKGQVSAPVAEKIPHVMTLHGVTRTDDYYWMRDDKRQDPKVLAHLNAENRYTQAYFKPLKS
LQDGLFNELTGRLVADESSVPYQWHQHSYYRRYQEGGEYPLIARKGSDGIEQMMLDVNERAKGHEFYGLGGVSVSPDETM
LAFGEDVLSRRVYNIYFKDIESGAMITDVLENTEGRIVWGNDNRHVFYIAKDLQTLLGYRVYRHELGTPQSRDVLVYEEQ
DDAYYISLGKSLDESQIVLFHESTTTSEVSVLDANDPLSLFKPVLAREEGHEYSVSKLGDSYYILTNWQATNFRLMKVAI
KDAADKSKWQEVVAHNPNARIEDELVLKDYLIIQTRENGLTRIKVMPFNGQKPFELSFDEPAYVLGLDVNAQQDSDKLRI
FYSSLTTPEAIYEYHLSNPDRRDLLKQEQVLGGFDASQYRAERLFVTARDGAKVPVSLVYRKDKFNKDGTNPLYQYGYGS
YGYTVEPDFSSSVISLLDRGFVYAIAHVRGSEMLGRPWYDAGKLLNKKNTFNDFIDVTTALTEQGYGDKNKVVASGGSAG
GLLMGAIANMAPEKYFAIAAHVPFVDVVTTMLDESIPLTTNEYDEWGNPNEKTYFDYMLSYSPYDNVADHEYPHLLVTTG
LHDSQVQYFEPAKWVAKLREVQNKWYKLDDKVLLFDVNMDAGHGGKSGRYRQYQDTAQEYAFFLSLLGMTK

Sequences:

>Translated_711_residues
MRTLLLTLGLAMLLPGCSTPKGQVSAPVAEKIPHVMTLHGVTRTDDYYWMRDDKRQDPKVLAHLNAENRYTQAYFKPLKS
LQDGLFNELTGRLVADESSVPYQWHQHSYYRRYQEGGEYPLIARKGSDGIEQMMLDVNERAKGHEFYGLGGVSVSPDETM
LAFGEDVLSRRVYNIYFKDIESGAMITDVLENTEGRIVWGNDNRHVFYIAKDLQTLLGYRVYRHELGTPQSRDVLVYEEQ
DDAYYISLGKSLDESQIVLFHESTTTSEVSVLDANDPLSLFKPVLAREEGHEYSVSKLGDSYYILTNWQATNFRLMKVAI
KDAADKSKWQEVVAHNPNARIEDELVLKDYLIIQTRENGLTRIKVMPFNGQKPFELSFDEPAYVLGLDVNAQQDSDKLRI
FYSSLTTPEAIYEYHLSNPDRRDLLKQEQVLGGFDASQYRAERLFVTARDGAKVPVSLVYRKDKFNKDGTNPLYQYGYGS
YGYTVEPDFSSSVISLLDRGFVYAIAHVRGSEMLGRPWYDAGKLLNKKNTFNDFIDVTTALTEQGYGDKNKVVASGGSAG
GLLMGAIANMAPEKYFAIAAHVPFVDVVTTMLDESIPLTTNEYDEWGNPNEKTYFDYMLSYSPYDNVADHEYPHLLVTTG
LHDSQVQYFEPAKWVAKLREVQNKWYKLDDKVLLFDVNMDAGHGGKSGRYRQYQDTAQEYAFFLSLLGMTK
>Mature_711_residues
MRTLLLTLGLAMLLPGCSTPKGQVSAPVAEKIPHVMTLHGVTRTDDYYWMRDDKRQDPKVLAHLNAENRYTQAYFKPLKS
LQDGLFNELTGRLVADESSVPYQWHQHSYYRRYQEGGEYPLIARKGSDGIEQMMLDVNERAKGHEFYGLGGVSVSPDETM
LAFGEDVLSRRVYNIYFKDIESGAMITDVLENTEGRIVWGNDNRHVFYIAKDLQTLLGYRVYRHELGTPQSRDVLVYEEQ
DDAYYISLGKSLDESQIVLFHESTTTSEVSVLDANDPLSLFKPVLAREEGHEYSVSKLGDSYYILTNWQATNFRLMKVAI
KDAADKSKWQEVVAHNPNARIEDELVLKDYLIIQTRENGLTRIKVMPFNGQKPFELSFDEPAYVLGLDVNAQQDSDKLRI
FYSSLTTPEAIYEYHLSNPDRRDLLKQEQVLGGFDASQYRAERLFVTARDGAKVPVSLVYRKDKFNKDGTNPLYQYGYGS
YGYTVEPDFSSSVISLLDRGFVYAIAHVRGSEMLGRPWYDAGKLLNKKNTFNDFIDVTTALTEQGYGDKNKVVASGGSAG
GLLMGAIANMAPEKYFAIAAHVPFVDVVTTMLDESIPLTTNEYDEWGNPNEKTYFDYMLSYSPYDNVADHEYPHLLVTTG
LHDSQVQYFEPAKWVAKLREVQNKWYKLDDKVLLFDVNMDAGHGGKSGRYRQYQDTAQEYAFFLSLLGMTK

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=711, Percent_Identity=24.6132208157525, Blast_Score=200, Evalue=5e-51,
Organism=Homo sapiens, GI284172438, Length=451, Percent_Identity=28.159645232816, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI284172431, Length=451, Percent_Identity=28.159645232816, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI284172420, Length=451, Percent_Identity=28.159645232816, Blast_Score=161, Evalue=3e-39,
Organism=Homo sapiens, GI284172413, Length=451, Percent_Identity=28.159645232816, Blast_Score=161, Evalue=3e-39,
Organism=Homo sapiens, GI70778815, Length=451, Percent_Identity=28.159645232816, Blast_Score=161, Evalue=3e-39,
Organism=Homo sapiens, GI108860686, Length=285, Percent_Identity=29.1228070175439, Blast_Score=124, Evalue=5e-28,
Organism=Homo sapiens, GI108860692, Length=215, Percent_Identity=33.0232558139535, Blast_Score=118, Evalue=2e-26,
Organism=Escherichia coli, GI1788150, Length=684, Percent_Identity=47.3684210526316, Blast_Score=639, Evalue=0.0,
Organism=Drosophila melanogaster, GI24583414, Length=730, Percent_Identity=25.8904109589041, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI221510989, Length=702, Percent_Identity=23.6467236467236, Blast_Score=171, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 80960; Mature: 80960

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLLLTLGLAMLLPGCSTPKGQVSAPVAEKIPHVMTLHGVTRTDDYYWMRDDKRQDPKV
CCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCEEEECCCEECCCEEEECCCCCCCCCE
LAHLNAENRYTQAYFKPLKSLQDGLFNELTGRLVADESSVPYQWHQHSYYRRYQEGGEYP
EEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHCCCCEE
LIARKGSDGIEQMMLDVNERAKGHEFYGLGGVSVSPDETMLAFGEDVLSRRVYNIYFKDI
EEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHEEEEEEC
ESGAMITDVLENTEGRIVWGNDNRHVFYIAKDLQTLLGYRVYRHELGTPQSRDVLVYEEQ
CCCCHHHHHHHCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
DDAYYISLGKSLDESQIVLFHESTTTSEVSVLDANDPLSLFKPVLAREEGHEYSVSKLGD
CCEEEEEECCCCCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEHHHCCC
SYYILTNWQATNFRLMKVAIKDAADKSKWQEVVAHNPNARIEDELVLKDYLIIQTRENGL
CEEEEEECCCCCEEEEEEEEHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCC
TRIKVMPFNGQKPFELSFDEPAYVLGLDVNAQQDSDKLRIFYSSLTTPEAIYEYHLSNPD
EEEEEEECCCCCCEEECCCCCEEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHCCCCC
RRDLLKQEQVLGGFDASQYRAERLFVTARDGAKVPVSLVYRKDKFNKDGTNPLYQYGYGS
HHHHHHHHHHHCCCCHHHHEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHCCCCC
YGYTVEPDFSSSVISLLDRGFVYAIAHVRGSEMLGRPWYDAGKLLNKKNTFNDFIDVTTA
CCCEECCCCCHHHHHHHHCCCEEEEEEECCCHHCCCCCHHHHHHHCCCCCHHHHHHHHHH
LTEQGYGDKNKVVASGGSAGGLLMGAIANMAPEKYFAIAAHVPFVDVVTTMLDESIPLTT
HHHCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCC
NEYDEWGNPNEKTYFDYMLSYSPYDNVADHEYPHLLVTTGLHDSQVQYFEPAKWVAKLRE
CCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHCCHHHHHHHHHH
VQNKWYKLDDKVLLFDVNMDAGHGGKSGRYRQYQDTAQEYAFFLSLLGMTK
HHHHHEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRTLLLTLGLAMLLPGCSTPKGQVSAPVAEKIPHVMTLHGVTRTDDYYWMRDDKRQDPKV
CCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCEEEECCCEECCCEEEECCCCCCCCCE
LAHLNAENRYTQAYFKPLKSLQDGLFNELTGRLVADESSVPYQWHQHSYYRRYQEGGEYP
EEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHCCCCEE
LIARKGSDGIEQMMLDVNERAKGHEFYGLGGVSVSPDETMLAFGEDVLSRRVYNIYFKDI
EEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHEEEEEEC
ESGAMITDVLENTEGRIVWGNDNRHVFYIAKDLQTLLGYRVYRHELGTPQSRDVLVYEEQ
CCCCHHHHHHHCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
DDAYYISLGKSLDESQIVLFHESTTTSEVSVLDANDPLSLFKPVLAREEGHEYSVSKLGD
CCEEEEEECCCCCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEHHHCCC
SYYILTNWQATNFRLMKVAIKDAADKSKWQEVVAHNPNARIEDELVLKDYLIIQTRENGL
CEEEEEECCCCCEEEEEEEEHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCC
TRIKVMPFNGQKPFELSFDEPAYVLGLDVNAQQDSDKLRIFYSSLTTPEAIYEYHLSNPD
EEEEEEECCCCCCEEECCCCCEEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHCCCCC
RRDLLKQEQVLGGFDASQYRAERLFVTARDGAKVPVSLVYRKDKFNKDGTNPLYQYGYGS
HHHHHHHHHHHCCCCHHHHEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHCCCCC
YGYTVEPDFSSSVISLLDRGFVYAIAHVRGSEMLGRPWYDAGKLLNKKNTFNDFIDVTTA
CCCEECCCCCHHHHHHHHCCCEEEEEEECCCHHCCCCCHHHHHHHCCCCCHHHHHHHHHH
LTEQGYGDKNKVVASGGSAGGLLMGAIANMAPEKYFAIAAHVPFVDVVTTMLDESIPLTT
HHHCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCC
NEYDEWGNPNEKTYFDYMLSYSPYDNVADHEYPHLLVTTGLHDSQVQYFEPAKWVAKLRE
CCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHCCHHHHHHHHHH
VQNKWYKLDDKVLLFDVNMDAGHGGKSGRYRQYQDTAQEYAFFLSLLGMTK
HHHHHEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]