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The map label for this gene is pntB [H]

Identifier: 113478078

GI number: 113478078

Start: 7226398

End: 7227804

Strand: Reverse

Name: pntB [H]

Synonym: Tery_4703

Alternate gene names: 113478078

Gene position: 7227804-7226398 (Counterclockwise)

Preceding gene: 113478079

Following gene: 113478077

Centisome position: 93.26

GC content: 42.5

Gene sequence:

>1407_bases
ATGACTGACTTTATACCAACTGGAATTCAGTTAAGCTATCTGGTAGCGGTATCTCTATTTTTTGTAGGCCTGAAAAAGCT
GGGTTCTCCAGCTACGGCCCGGAATGGTAATTTGTTAGCATCAGTAGGAATGTTGATTGCTATTGTAGCAACCCTACTAG
AAAAAGAAGTTTTGAACTATGAGATGATTTTATTGGGTATTGTCATCGGTTCAATTATTGGAGCGATCGCTGCAGTGAAA
GTAGAAATGACTGCCATGCCTCAAATGGTTGGTTTATTCAACGGTTTGGGTGGTGCTGCTTCTGCAATGGTTGCAGTCGG
TGAATTTTGGAGGTTTCTAGCTGTTGGGAGCTCACCCCCATTACCCACTACTATTACGGCATTACTAGGGGTATTAATTG
GTGGGGTAACTTTTACCGGCTCCTTAATTGCTTTTGCCAAACTACAGGGAATTATAAGTGGTTCTCCGATTACTTTCCCA
TTGCAACAACCTGTTAATGCTCTATTATTTGGTGGGTTTATTGTTGCCAGTGTTTATATGTGTGTCACACCATTTAATGT
ACCCGTATTTTTGGCATTGCTAGGTGTGTCTTTGGTATTAGGTATAATGTTTGTGGTTCCCATTGGTGGCGGTGATATGC
CAGTGGTAATTTCTTTGTTGAACTCATTCTCTGGATTAGCTGCTAGTGCTGCTGGTTTTGTGGTGATGAACAATATGTTA
ATCATCGCTGGTGCATTAGTTGGTGCTTCTGGTATTATTCTTACAGTTATCATGTGTAAGGGTATGAACCGTTCCTTAAC
TAATGTACTATTTGCTGCATTTGGTACTGGTGAAGGTGGTAGCGTTGCTGCCGGTACAGGTGGCAAGACTGATAATACGG
TTCGTAGTATTGACCCAGAAGAGGGTGCAATGATGTTGGGTTATGCTCGCTCTGTAGTAATTGTGCCTGGTTATGGTATG
GCCGTTGCTCAAGCTCAACATTCTGTCCGGGAATTATCAGACCAGTTGGAAGGATTAGGGGTTGAGGTTAAATATGCTAT
TCACCCAGTTGCTGGCCGGATGCCTGGACACATGAATGTATTATTAGCAGAAGCAAATGTCCCTTATCCTCAATTATACG
ATATGGATGACATCAATCCTCATTTTGACCAGGCAGATGTGGCCTTAGTGATTGGGGCTAATGATGTGGTAAATCCGGCA
GCTCGTGCGGACCAGAATAGTCCTATATATGGAATGCCAATTCTAGATGTAGATAAGGCTAAGCATACTATTGTGATTAA
ACGCGGCCTCAGCACTGGTTTTGCTGGAGTGGACAATGATTTGTTCTACAAGGACAAGACTATGATGCTGTTTGGCAGTG
CTAAGGATATGGTTGCTAAGTTGGTTTCTGAGGTCAAACAACTTTAA

Upstream 100 bases:

>100_bases
TAGGTTTAATTGCTGTAGTCTTTGCCACCATTAATGTAGTTGGTGGCTTTTTGGTAACGGATAGAATGTTGCAAATGTTT
AAGAAGAAGGAGGCTACATC

Downstream 100 bases:

>100_bases
TATTTAGAATAACTTATTCTATTAATCCTGCCCTATCTATATTTAATGAACAATGCTGAATGCTTCTGCAAGTGTTACTC
AGCAAGCTATTGTTCAGTTT

Product: NAD(P) transhydrogenase subunit beta

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MTDFIPTGIQLSYLVAVSLFFVGLKKLGSPATARNGNLLASVGMLIAIVATLLEKEVLNYEMILLGIVIGSIIGAIAAVK
VEMTAMPQMVGLFNGLGGAASAMVAVGEFWRFLAVGSSPPLPTTITALLGVLIGGVTFTGSLIAFAKLQGIISGSPITFP
LQQPVNALLFGGFIVASVYMCVTPFNVPVFLALLGVSLVLGIMFVVPIGGGDMPVVISLLNSFSGLAASAAGFVVMNNML
IIAGALVGASGIILTVIMCKGMNRSLTNVLFAAFGTGEGGSVAAGTGGKTDNTVRSIDPEEGAMMLGYARSVVIVPGYGM
AVAQAQHSVRELSDQLEGLGVEVKYAIHPVAGRMPGHMNVLLAEANVPYPQLYDMDDINPHFDQADVALVIGANDVVNPA
ARADQNSPIYGMPILDVDKAKHTIVIKRGLSTGFAGVDNDLFYKDKTMMLFGSAKDMVAKLVSEVKQL

Sequences:

>Translated_468_residues
MTDFIPTGIQLSYLVAVSLFFVGLKKLGSPATARNGNLLASVGMLIAIVATLLEKEVLNYEMILLGIVIGSIIGAIAAVK
VEMTAMPQMVGLFNGLGGAASAMVAVGEFWRFLAVGSSPPLPTTITALLGVLIGGVTFTGSLIAFAKLQGIISGSPITFP
LQQPVNALLFGGFIVASVYMCVTPFNVPVFLALLGVSLVLGIMFVVPIGGGDMPVVISLLNSFSGLAASAAGFVVMNNML
IIAGALVGASGIILTVIMCKGMNRSLTNVLFAAFGTGEGGSVAAGTGGKTDNTVRSIDPEEGAMMLGYARSVVIVPGYGM
AVAQAQHSVRELSDQLEGLGVEVKYAIHPVAGRMPGHMNVLLAEANVPYPQLYDMDDINPHFDQADVALVIGANDVVNPA
ARADQNSPIYGMPILDVDKAKHTIVIKRGLSTGFAGVDNDLFYKDKTMMLFGSAKDMVAKLVSEVKQL
>Mature_467_residues
TDFIPTGIQLSYLVAVSLFFVGLKKLGSPATARNGNLLASVGMLIAIVATLLEKEVLNYEMILLGIVIGSIIGAIAAVKV
EMTAMPQMVGLFNGLGGAASAMVAVGEFWRFLAVGSSPPLPTTITALLGVLIGGVTFTGSLIAFAKLQGIISGSPITFPL
QQPVNALLFGGFIVASVYMCVTPFNVPVFLALLGVSLVLGIMFVVPIGGGDMPVVISLLNSFSGLAASAAGFVVMNNMLI
IAGALVGASGIILTVIMCKGMNRSLTNVLFAAFGTGEGGSVAAGTGGKTDNTVRSIDPEEGAMMLGYARSVVIVPGYGMA
VAQAQHSVRELSDQLEGLGVEVKYAIHPVAGRMPGHMNVLLAEANVPYPQLYDMDDINPHFDQADVALVIGANDVVNPAA
RADQNSPIYGMPILDVDKAKHTIVIKRGLSTGFAGVDNDLFYKDKTMMLFGSAKDMVAKLVSEVKQL

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=475, Percent_Identity=43.1578947368421, Blast_Score=322, Evalue=6e-88,
Organism=Homo sapiens, GI122939153, Length=475, Percent_Identity=43.1578947368421, Blast_Score=322, Evalue=6e-88,
Organism=Escherichia coli, GI1787886, Length=451, Percent_Identity=48.3370288248337, Blast_Score=376, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17550456, Length=459, Percent_Identity=44.2265795206972, Blast_Score=341, Evalue=6e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 48613; Mature: 48482

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CEEEEEEECCCCCCCCCCCCEEECCCEEEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDFIPTGIQLSYLVAVSLFFVGLKKLGSPATARNGNLLASVGMLIAIVATLLEKEVLNY
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH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CEEEEEEECCCCCCCCCCCCEEECCCEEEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]