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The map label for this gene is pkn1 [H]

Identifier: 113477941

GI number: 113477941

Start: 7012199

End: 7013062

Strand: Reverse

Name: pkn1 [H]

Synonym: Tery_4550

Alternate gene names: 113477941

Gene position: 7013062-7012199 (Counterclockwise)

Preceding gene: 113477942

Following gene: 113477940

Centisome position: 90.49

GC content: 41.09

Gene sequence:

>864_bases
ATGACTCAACCATCAATATCAGAATCAGAAAAAGGAGACCTATTCACTTTTGAAATTATAAGCGTCAACAACTCTGGCGG
TATTATTCATCGTAGCCAGGGAAACGCCAGACAAAAAATAGAAAACTTAGGTAACGACATTAAATTGGAAATAGTTTATA
CTCCTGGTGGAAGCTTTATCATGGGATCCCCAGAAGATGAAGCCAAAAGAAACCGTAGTGAAGGCCCCCAACATCAAGTA
ACTCTTCAACCCTTTTATATGAGCAAATATCCCATTACTCAAAACCAATACCAGGCAATTATGGGAAATAACCCTTCTAA
GTTCAAAGGTGCAAACCGCCCTGTAGAAAAAGTAAACTGGTACCACGCAACAGAATTTTGTCAAAAGCTATCCGAGAAAA
CCGGGAAGAACTACAGACTACCCAGCGAAAGTCAGTGGGAATATGCTTGCCGTGCAGGAACAACAACACCTTTTTACTTT
GGCGAAACTATAACCTCTGAGTTAGTTAACTACAACAGTAACTACACTTATAGTAACGCACCGAAAGGAAAACATCCTGA
AGAAACAACAAATGTAGGAATTTATCCTCCCAATACCTTTGGTTTATATGATATGCACGGCAATGTGTGGGAGTGGTGTC
AAGATGTTTTGCATAACAACTATGAAGGAGCTCCTACAGATGGAAGTGCTCGGGAAACTGGAAATGACAACTTTTCTCCA
CTGCGAGGAGGATCTTGGAACTTCTATCCTCATCATTGTCGTTCTGCGTCTCGCATCAACGACTATAAGCGCAGCTTCTA
CAAACACTTTATTGGATTTCGTGTAGTATGGAACGCCGGGATGGAAAAGTATGGGAAAGGATAG

Upstream 100 bases:

>100_bases
ACTAATTATAGTATGGAGAATTTCATATCGACAGTACGCTATATATAGCGTACTTGCGTAAGTCCTGATCATATAGAAAT
AATTAATTCTTGTAATTGAA

Downstream 100 bases:

>100_bases
AACTGACACTGACGGGGGAAAGTTTTTGAACACTAATTATCCAAACATGATATAATTAGCATCTCACGGGGTGACAAGCT
AGTTGAAAGCTATATATAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MTQPSISESEKGDLFTFEIISVNNSGGIIHRSQGNARQKIENLGNDIKLEIVYTPGGSFIMGSPEDEAKRNRSEGPQHQV
TLQPFYMSKYPITQNQYQAIMGNNPSKFKGANRPVEKVNWYHATEFCQKLSEKTGKNYRLPSESQWEYACRAGTTTPFYF
GETITSELVNYNSNYTYSNAPKGKHPEETTNVGIYPPNTFGLYDMHGNVWEWCQDVLHNNYEGAPTDGSARETGNDNFSP
LRGGSWNFYPHHCRSASRINDYKRSFYKHFIGFRVVWNAGMEKYGKG

Sequences:

>Translated_287_residues
MTQPSISESEKGDLFTFEIISVNNSGGIIHRSQGNARQKIENLGNDIKLEIVYTPGGSFIMGSPEDEAKRNRSEGPQHQV
TLQPFYMSKYPITQNQYQAIMGNNPSKFKGANRPVEKVNWYHATEFCQKLSEKTGKNYRLPSESQWEYACRAGTTTPFYF
GETITSELVNYNSNYTYSNAPKGKHPEETTNVGIYPPNTFGLYDMHGNVWEWCQDVLHNNYEGAPTDGSARETGNDNFSP
LRGGSWNFYPHHCRSASRINDYKRSFYKHFIGFRVVWNAGMEKYGKG
>Mature_286_residues
TQPSISESEKGDLFTFEIISVNNSGGIIHRSQGNARQKIENLGNDIKLEIVYTPGGSFIMGSPEDEAKRNRSEGPQHQVT
LQPFYMSKYPITQNQYQAIMGNNPSKFKGANRPVEKVNWYHATEFCQKLSEKTGKNYRLPSESQWEYACRAGTTTPFYFG
ETITSELVNYNSNYTYSNAPKGKHPEETTNVGIYPPNTFGLYDMHGNVWEWCQDVLHNNYEGAPTDGSARETGNDNFSPL
RGGSWNFYPHHCRSASRINDYKRSFYKHFIGFRVVWNAGMEKYGKG

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=269, Percent_Identity=26.3940520446097, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI38202250, Length=294, Percent_Identity=24.4897959183673, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI257470977, Length=237, Percent_Identity=24.8945147679325, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 32699; Mature: 32568

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPSISESEKGDLFTFEIISVNNSGGIIHRSQGNARQKIENLGNDIKLEIVYTPGGSFI
CCCCCCCCCCCCCEEEEEEEEECCCCCEEECCCCCHHHHHHHCCCCEEEEEEECCCCCEE
MGSPEDEAKRNRSEGPQHQVTLQPFYMSKYPITQNQYQAIMGNNPSKFKGANRPVEKVNW
ECCCHHHHHHCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCHHCCCCCCCHHHHCH
YHATEFCQKLSEKTGKNYRLPSESQWEYACRAGTTTPFYFGETITSELVNYNSNYTYSNA
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCEECCHHHHHHHHHCCCCCEECCC
PKGKHPEETTNVGIYPPNTFGLYDMHGNVWEWCQDVLHNNYEGAPTDGSARETGNDNFSP
CCCCCCCCCCCCCEECCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
LRGGSWNFYPHHCRSASRINDYKRSFYKHFIGFRVVWNAGMEKYGKG
CCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHEEEHHCHHHHCCC
>Mature Secondary Structure 
TQPSISESEKGDLFTFEIISVNNSGGIIHRSQGNARQKIENLGNDIKLEIVYTPGGSFI
CCCCCCCCCCCCEEEEEEEEECCCCCEEECCCCCHHHHHHHCCCCEEEEEEECCCCCEE
MGSPEDEAKRNRSEGPQHQVTLQPFYMSKYPITQNQYQAIMGNNPSKFKGANRPVEKVNW
ECCCHHHHHHCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCHHCCCCCCCHHHHCH
YHATEFCQKLSEKTGKNYRLPSESQWEYACRAGTTTPFYFGETITSELVNYNSNYTYSNA
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCEECCHHHHHHHHHCCCCCEECCC
PKGKHPEETTNVGIYPPNTFGLYDMHGNVWEWCQDVLHNNYEGAPTDGSARETGNDNFSP
CCCCCCCCCCCCCEECCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
LRGGSWNFYPHHCRSASRINDYKRSFYKHFIGFRVVWNAGMEKYGKG
CCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHEEEHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]