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The map label for this gene is uvrC

Identifier: 113476857

GI number: 113476857

Start: 5124169

End: 5126037

Strand: Reverse

Name: uvrC

Synonym: Tery_3342

Alternate gene names: 113476857

Gene position: 5126037-5124169 (Counterclockwise)

Preceding gene: 113476858

Following gene: 113476856

Centisome position: 66.14

GC content: 37.83

Gene sequence:

>1869_bases
ATGATAACTCAAATTTTACCTATAATAAAAGACTCTGAACGTTTAGAAAATAGACTCAAAGAGATTCCCCAAACTCCGGG
AGTTTATCTCATGCGTGATCGTAGCGATCGCATCCTTTATATTGGTAAATCTAAAAAACTTAGAAACCGAGTTCGTTCCT
ATTTTCGAGATGGAAAAAATCACACTCATCGTATCAGTTTAATGATACAACAAATCGTTGAAATTGAATTTATTGTCACA
GATACAGAAGCTGAAGCTTTAGCATTAGAAGCTAATCTTGTTAAGCAACATCAACCATATTTTAATGTCTTACTCAAGGA
TGATAAAAAATATCCCTATCTTTGTATAACTTGGTCGGAAGATTATCCGAGAATTTTTATTACTAGAAAACGCAGATTAG
GTAAAGCTAAAGACCGTTATTATGGTCCTTATGTGGATACTAGATTACTCCGAAATACTCTACATTTAGTTAAACGAATT
TTTCCCCTACGTCAAAGACCAAAACCTTTATTTAAGGACCGCTCTTGTCTGAATTATGATATTGGTCGTTGCCCTGGAGT
TTGTCAGGAGTTAATTACTCCAGAGGAATATCATAAAATTGTGCAAAGAGTGGCAATGATTTTTCAAGGTCGAACTGGAG
AATTAATTGATATTTTAAATACTCAAATGGAAAAAGAAGCGGAAGCGCTAAATTTTGAAAAAGCAGCATTTATTCGTGAC
CAAATTAGAGGTTTAAATTCTTTAAATGCTGATCAAAAAGTTTCTTTACCAGATGATAGAGTTTCTAGAGATGCAATTGC
TTTGGCGGGAAATCATCAAATTGCTTGTGTTCAACTATTCCAAATTCGGGCAGGAAAATTAGTAGGTAGGTTGGGATTTA
TTGCTGAAATTCCTGATTTAGGAACTGCAGAAAATCAGGAGTTGGGAGTAATTTTGCAGCGGGTTTTAGAATCCCATTAT
CAAATAGTAGAATCTGTAGAAATTCCTACGGAAATTATTGTGCAAAATGAGTTGCCGGAGAGTAATTTTTTGCAAAATTG
GTTAACAGAAAAGAAGGGTAAAAAAGTAGAAATTTTTGTACCTCAACGCCAGGGGAAAGCTGAATTAATTGAGATGGTAA
AAAAGAATGCTGAGTATGAGTTATTGCGGTTGGCAAAAATGAGCGATCGCAATAATGAAGCGATGACAGATTTAGCAGAA
ATCTTAGATTTACCAGAGTTACCTCACCGGATAGAGGGTTATGATATTTCCCACATTCAAGGTTCGGATGCGGTGGCATC
ACGGGTAGTGTTTATTGACGGTTTGCCAGCAAAACAACATTATCGACATTATAAAATTAAAAACCCAGAAGTGCGTTCCG
GTCATTCTGATGATTTTGCCAGTATGGCTGAGGTTATTGGGCGACGGTTTCGTGACTATGAAAAACAAACTACTACAGAC
AAACCAGATTTAATTATGATAGATGGTGGGAAAGGGCAACTGTCAGCAGTAGTGGCAGTGATGGAAGAGATGAATATATT
AGAAGAAGTGCGGGTGGTGAGTTTGGCAAAACAACGGGAGGAGATTTTTTTGCCTGGGGAGTCTGAACCTTTAAGAACTG
ATGCGGAACAACCGGGGGTGCAGTTGTTGCGGAGGCTGCGGGATGAGGCTCATAGATTTGCTGTGAGTTTTCATCGGGAT
AGAAGAAGTCAGAGGATGAAGCGATCGCGTTTAGATGAGATTCCTGGTTTAGGGCAACATCGACAAAAGTTGTTATTGGG
GCATTTTCATTCTGTTGATTATATTAGGATGGCAACGGTGGAACAGTTGGCAGAAGTGTCGGGAGTCGGACCTAAGTTGG
CACAACAGATTTATGATTATTTTCATTAA

Upstream 100 bases:

>100_bases
AAAATTTACTATTTCTAACTTCCTACTTTAGTAGGAGTTACTATTAACTGAAAAAGCTCATAACTGCAATAGTAATAACT
TAAAAATCTGATAACTGAGT

Downstream 100 bases:

>100_bases
AATAGGGAGTAGGAAACTCAAATTTTCAGGGTTTACAGAAAGGCGTCAAATGTAGTGTAAAAGTCTCAAATAATTACCTT
AAACACTATATATAGGAGCA

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MITQILPIIKDSERLENRLKEIPQTPGVYLMRDRSDRILYIGKSKKLRNRVRSYFRDGKNHTHRISLMIQQIVEIEFIVT
DTEAEALALEANLVKQHQPYFNVLLKDDKKYPYLCITWSEDYPRIFITRKRRLGKAKDRYYGPYVDTRLLRNTLHLVKRI
FPLRQRPKPLFKDRSCLNYDIGRCPGVCQELITPEEYHKIVQRVAMIFQGRTGELIDILNTQMEKEAEALNFEKAAFIRD
QIRGLNSLNADQKVSLPDDRVSRDAIALAGNHQIACVQLFQIRAGKLVGRLGFIAEIPDLGTAENQELGVILQRVLESHY
QIVESVEIPTEIIVQNELPESNFLQNWLTEKKGKKVEIFVPQRQGKAELIEMVKKNAEYELLRLAKMSDRNNEAMTDLAE
ILDLPELPHRIEGYDISHIQGSDAVASRVVFIDGLPAKQHYRHYKIKNPEVRSGHSDDFASMAEVIGRRFRDYEKQTTTD
KPDLIMIDGGKGQLSAVVAVMEEMNILEEVRVVSLAKQREEIFLPGESEPLRTDAEQPGVQLLRRLRDEAHRFAVSFHRD
RRSQRMKRSRLDEIPGLGQHRQKLLLGHFHSVDYIRMATVEQLAEVSGVGPKLAQQIYDYFH

Sequences:

>Translated_622_residues
MITQILPIIKDSERLENRLKEIPQTPGVYLMRDRSDRILYIGKSKKLRNRVRSYFRDGKNHTHRISLMIQQIVEIEFIVT
DTEAEALALEANLVKQHQPYFNVLLKDDKKYPYLCITWSEDYPRIFITRKRRLGKAKDRYYGPYVDTRLLRNTLHLVKRI
FPLRQRPKPLFKDRSCLNYDIGRCPGVCQELITPEEYHKIVQRVAMIFQGRTGELIDILNTQMEKEAEALNFEKAAFIRD
QIRGLNSLNADQKVSLPDDRVSRDAIALAGNHQIACVQLFQIRAGKLVGRLGFIAEIPDLGTAENQELGVILQRVLESHY
QIVESVEIPTEIIVQNELPESNFLQNWLTEKKGKKVEIFVPQRQGKAELIEMVKKNAEYELLRLAKMSDRNNEAMTDLAE
ILDLPELPHRIEGYDISHIQGSDAVASRVVFIDGLPAKQHYRHYKIKNPEVRSGHSDDFASMAEVIGRRFRDYEKQTTTD
KPDLIMIDGGKGQLSAVVAVMEEMNILEEVRVVSLAKQREEIFLPGESEPLRTDAEQPGVQLLRRLRDEAHRFAVSFHRD
RRSQRMKRSRLDEIPGLGQHRQKLLLGHFHSVDYIRMATVEQLAEVSGVGPKLAQQIYDYFH
>Mature_622_residues
MITQILPIIKDSERLENRLKEIPQTPGVYLMRDRSDRILYIGKSKKLRNRVRSYFRDGKNHTHRISLMIQQIVEIEFIVT
DTEAEALALEANLVKQHQPYFNVLLKDDKKYPYLCITWSEDYPRIFITRKRRLGKAKDRYYGPYVDTRLLRNTLHLVKRI
FPLRQRPKPLFKDRSCLNYDIGRCPGVCQELITPEEYHKIVQRVAMIFQGRTGELIDILNTQMEKEAEALNFEKAAFIRD
QIRGLNSLNADQKVSLPDDRVSRDAIALAGNHQIACVQLFQIRAGKLVGRLGFIAEIPDLGTAENQELGVILQRVLESHY
QIVESVEIPTEIIVQNELPESNFLQNWLTEKKGKKVEIFVPQRQGKAELIEMVKKNAEYELLRLAKMSDRNNEAMTDLAE
ILDLPELPHRIEGYDISHIQGSDAVASRVVFIDGLPAKQHYRHYKIKNPEVRSGHSDDFASMAEVIGRRFRDYEKQTTTD
KPDLIMIDGGKGQLSAVVAVMEEMNILEEVRVVSLAKQREEIFLPGESEPLRTDAEQPGVQLLRRLRDEAHRFAVSFHRD
RRSQRMKRSRLDEIPGLGQHRQKLLLGHFHSVDYIRMATVEQLAEVSGVGPKLAQQIYDYFH

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain

Homologues:

Organism=Escherichia coli, GI87081999, Length=613, Percent_Identity=34.257748776509, Blast_Score=338, Evalue=4e-94,
Organism=Escherichia coli, GI1788037, Length=187, Percent_Identity=31.5508021390374, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UVRC_TRIEI (Q10Z79)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_722918.1
- ProteinModelPortal:   Q10Z79
- STRING:   Q10Z79
- GeneID:   4243513
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_3342
- NMPDR:   fig|203124.1.peg.2847
- eggNOG:   COG0322
- HOGENOM:   HBG566029
- OMA:   DVLYVGK
- PhylomeDB:   Q10Z79
- ProtClustDB:   PRK00558
- BioCyc:   TERY203124:TERY_3342-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00203
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305
- SMART:   SM00465
- SMART:   SM00278
- TIGRFAMs:   TIGR00194

Pfam domain/function: PF01541 GIY-YIG; PF00633 HHH; PF02151 UVR; PF08459 UvrC_HhH_N; SSF47781 RuvA_2_like; SSF46600 UvrB_C; SSF82771 UvrC_N

EC number: NA

Molecular weight: Translated: 72018; Mature: 72018

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50151 UVR; PS50164 UVRC_1; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITQILPIIKDSERLENRLKEIPQTPGVYLMRDRSDRILYIGKSKKLRNRVRSYFRDGKN
CCCHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHCCCC
HTHRISLMIQQIVEIEFIVTDTEAEALALEANLVKQHQPYFNVLLKDDKKYPYLCITWSE
CHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHCCCHHEEEEECCCCCCEEEEEECC
DYPRIFITRKRRLGKAKDRYYGPYVDTRLLRNTLHLVKRIFPLRQRPKPLFKDRSCLNYD
CCCEEEEEEHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCC
IGRCPGVCQELITPEEYHKIVQRVAMIFQGRTGELIDILNTQMEKEAEALNFEKAAFIRD
CCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHH
QIRGLNSLNADQKVSLPDDRVSRDAIALAGNHQIACVQLFQIRAGKLVGRLGFIAEIPDL
HHHCCCCCCCCCCCCCCCHHHCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCC
GTAENQELGVILQRVLESHYQIVESVEIPTEIIVQNELPESNFLQNWLTEKKGKKVEIFV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHHCCCCEEEEEE
PQRQGKAELIEMVKKNAEYELLRLAKMSDRNNEAMTDLAEILDLPELPHRIEGYDISHIQ
CCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GSDAVASRVVFIDGLPAKQHYRHYKIKNPEVRSGHSDDFASMAEVIGRRFRDYEKQTTTD
CCHHHHHEEEEEECCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
KPDLIMIDGGKGQLSAVVAVMEEMNILEEVRVVSLAKQREEIFLPGESEPLRTDAEQPGV
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCHHH
QLLRRLRDEAHRFAVSFHRDRRSQRMKRSRLDEIPGLGQHRQKLLLGHFHSVDYIRMATV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHH
EQLAEVSGVGPKLAQQIYDYFH
HHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MITQILPIIKDSERLENRLKEIPQTPGVYLMRDRSDRILYIGKSKKLRNRVRSYFRDGKN
CCCHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHCCCC
HTHRISLMIQQIVEIEFIVTDTEAEALALEANLVKQHQPYFNVLLKDDKKYPYLCITWSE
CHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHCCCHHEEEEECCCCCCEEEEEECC
DYPRIFITRKRRLGKAKDRYYGPYVDTRLLRNTLHLVKRIFPLRQRPKPLFKDRSCLNYD
CCCEEEEEEHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCC
IGRCPGVCQELITPEEYHKIVQRVAMIFQGRTGELIDILNTQMEKEAEALNFEKAAFIRD
CCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHH
QIRGLNSLNADQKVSLPDDRVSRDAIALAGNHQIACVQLFQIRAGKLVGRLGFIAEIPDL
HHHCCCCCCCCCCCCCCCHHHCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCC
GTAENQELGVILQRVLESHYQIVESVEIPTEIIVQNELPESNFLQNWLTEKKGKKVEIFV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHHCCCCEEEEEE
PQRQGKAELIEMVKKNAEYELLRLAKMSDRNNEAMTDLAEILDLPELPHRIEGYDISHIQ
CCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GSDAVASRVVFIDGLPAKQHYRHYKIKNPEVRSGHSDDFASMAEVIGRRFRDYEKQTTTD
CCHHHHHEEEEEECCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
KPDLIMIDGGKGQLSAVVAVMEEMNILEEVRVVSLAKQREEIFLPGESEPLRTDAEQPGV
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCHHH
QLLRRLRDEAHRFAVSFHRDRRSQRMKRSRLDEIPGLGQHRQKLLLGHFHSVDYIRMATV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHH
EQLAEVSGVGPKLAQQIYDYFH
HHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA