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The map label for this gene is dapL

Identifier: 113476813

GI number: 113476813

Start: 5050838

End: 5052073

Strand: Reverse

Name: dapL

Synonym: Tery_3293

Alternate gene names: 113476813

Gene position: 5052073-5050838 (Counterclockwise)

Preceding gene: 113476814

Following gene: 113476812

Centisome position: 65.19

GC content: 40.29

Gene sequence:

>1236_bases
ATGGCAACAATTAACGATAACTACCTCAAACTTAAAGCCGGATACTTATTTCCAGAAATAGCTAGACGAGTTAATACATT
TGCTGAAGCACACCCGGAAGCCCAGATCATTAAATTGGGTATTGGGGATGTAACTGAGCCATTGCCAAAAGCTTGTATTC
AGGCTATGACTAAAGCTGTAGCAGAAATGGGCGATCGCTCAACTTTTAAGGGTTATGGCCCAGAGCAAGGTTATGCTTGG
TTGCGCGAAAAAATTGCTGCTCAAGATTTTCAGGGGCGAGGATGTGATATTGATGCCTCGGAAATTTTCATTTCTGATGG
ATCTAAGTGTGATAGTGGTAATATTCTAGATATTATTGGTAATAATAATACTATTGCGGTGACTGATCCAGTATACCCAG
TGTATGTAGATACGAATGTAATGGCGGGTAACACTGGTGCTGTAAATGAGAAAGGGGAGTATGAGGGTTTAGTTTATTTA
CCAATAAGAGCGGAAAATAATTTTACTGCGGAAATTCCTACTCAAAAGGTAGATTTGATTTATTTGTGTTTTCCCAATAA
CCCTACTGGTGCGACTGCCACTAAAGAATATTTGCAAACATGGGTAAATTATGCTAGAGCGAATGATGCCATTATTTTAT
TCGATGCTGCTTACGAAGCATTTATTACCGATGCCAGTCTTCCTCATTCTATTTATGAGATAGAAGGAGCAAAAGAATGT
GCCATTGAATTTCGCTCCTTTTCCAAGAATGCTGGTTTTACAGGTACTCGTTGTGCGTTGACTGTCGTACCCAAAACTCT
GAAAGGGAAAGCTGCTGATGGTAGCGATGTAGAATTATGGAAATTGTGGAACCGTCGCCAGTCTACTAAATTTAATGGAG
TTTCTTATATTGTGCAGCGAGGTGCAGAGGCAGTTTACTCCGAAGAAGGGAAAGCACAGGTTAAGGGGTTGATCCAATTT
TATTTAGAGAATGCGAAAATTATCTGCTCTCAGTTACAAGCAGCAGGTTTAACTGTTTATGGTGGGGTAAATGCGCCTTA
TGTTTGGGTGCAGACTCCTACAGGTTTGTCGAGTTGGGATTTTTTCGATAAGCTGTTGCAAAATTGTAATGTTGTGGGAA
CTCCCGGTTCCGGCTTTGGTGCTGCAGGTGAAGGTTACTTCCGCATTTCTAGTTTTAATAGTCGGGAAAATGTTAATGAA
GCGATGAAACGGATAACTGAGAAATTTAAAGTTTAG

Upstream 100 bases:

>100_bases
TGAATGGTTGGGTTTTACGAGAACCAAAAGTAATGTTGCCTAATTAACAAAGGTTAGGATAATTTGAGATACTGTTACAG
GTGACTTTTATTAATCTACC

Downstream 100 bases:

>100_bases
ACAAGCTATCGCTCTTAACTTACAGAGAAACCGGGTTGAACGAAGAAATTTTCTAAGAGTAATTATAGTCATAAACCCGG
TTTCTTATAATGTTATAAAT

Product: L,L-diaminopimelate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MATINDNYLKLKAGYLFPEIARRVNTFAEAHPEAQIIKLGIGDVTEPLPKACIQAMTKAVAEMGDRSTFKGYGPEQGYAW
LREKIAAQDFQGRGCDIDASEIFISDGSKCDSGNILDIIGNNNTIAVTDPVYPVYVDTNVMAGNTGAVNEKGEYEGLVYL
PIRAENNFTAEIPTQKVDLIYLCFPNNPTGATATKEYLQTWVNYARANDAIILFDAAYEAFITDASLPHSIYEIEGAKEC
AIEFRSFSKNAGFTGTRCALTVVPKTLKGKAADGSDVELWKLWNRRQSTKFNGVSYIVQRGAEAVYSEEGKAQVKGLIQF
YLENAKIICSQLQAAGLTVYGGVNAPYVWVQTPTGLSSWDFFDKLLQNCNVVGTPGSGFGAAGEGYFRISSFNSRENVNE
AMKRITEKFKV

Sequences:

>Translated_411_residues
MATINDNYLKLKAGYLFPEIARRVNTFAEAHPEAQIIKLGIGDVTEPLPKACIQAMTKAVAEMGDRSTFKGYGPEQGYAW
LREKIAAQDFQGRGCDIDASEIFISDGSKCDSGNILDIIGNNNTIAVTDPVYPVYVDTNVMAGNTGAVNEKGEYEGLVYL
PIRAENNFTAEIPTQKVDLIYLCFPNNPTGATATKEYLQTWVNYARANDAIILFDAAYEAFITDASLPHSIYEIEGAKEC
AIEFRSFSKNAGFTGTRCALTVVPKTLKGKAADGSDVELWKLWNRRQSTKFNGVSYIVQRGAEAVYSEEGKAQVKGLIQF
YLENAKIICSQLQAAGLTVYGGVNAPYVWVQTPTGLSSWDFFDKLLQNCNVVGTPGSGFGAAGEGYFRISSFNSRENVNE
AMKRITEKFKV
>Mature_410_residues
ATINDNYLKLKAGYLFPEIARRVNTFAEAHPEAQIIKLGIGDVTEPLPKACIQAMTKAVAEMGDRSTFKGYGPEQGYAWL
REKIAAQDFQGRGCDIDASEIFISDGSKCDSGNILDIIGNNNTIAVTDPVYPVYVDTNVMAGNTGAVNEKGEYEGLVYLP
IRAENNFTAEIPTQKVDLIYLCFPNNPTGATATKEYLQTWVNYARANDAIILFDAAYEAFITDASLPHSIYEIEGAKECA
IEFRSFSKNAGFTGTRCALTVVPKTLKGKAADGSDVELWKLWNRRQSTKFNGVSYIVQRGAEAVYSEEGKAQVKGLIQFY
LENAKIICSQLQAAGLTVYGGVNAPYVWVQTPTGLSSWDFFDKLLQNCNVVGTPGSGFGAAGEGYFRISSFNSRENVNEA
MKRITEKFKV

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily

Homologues:

Organism=Escherichia coli, GI1788722, Length=382, Percent_Identity=26.1780104712042, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPAT_TRIEI (Q10ZC3)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_722874.1
- ProteinModelPortal:   Q10ZC3
- SMR:   Q10ZC3
- STRING:   Q10ZC3
- GeneID:   4243599
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_3293
- NMPDR:   fig|203124.1.peg.2612
- eggNOG:   COG0436
- HOGENOM:   HBG645860
- OMA:   VDLIYLC
- ProtClustDB:   PRK07590
- BioCyc:   TERY203124:TERY_3293-MONOMER
- HAMAP:   MF_01642
- InterPro:   IPR004839
- InterPro:   IPR019942
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- TIGRFAMs:   TIGR03542

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.83

Molecular weight: Translated: 45065; Mature: 44934

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: BINDING 42-42 BINDING 72-72 BINDING 75-75 BINDING 109-109 BINDING 132-132 BINDING 187-187 BINDING 187-187 BINDING 215-215 BINDING 218-218 BINDING 246-246 BINDING 248-248 BINDING 257-257 BINDING 292-292 BINDING 388-388

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATINDNYLKLKAGYLFPEIARRVNTFAEAHPEAQIIKLGIGDVTEPLPKACIQAMTKAV
CCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
AEMGDRSTFKGYGPEQGYAWLREKIAAQDFQGRGCDIDASEIFISDGSKCDSGNILDIIG
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHEEEEECCCCCCCCCEEEEEC
NNNTIAVTDPVYPVYVDTNVMAGNTGAVNEKGEYEGLVYLPIRAENNFTAEIPTQKVDLI
CCCEEEEECCEEEEEEECEEEECCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCCCEE
YLCFPNNPTGATATKEYLQTWVNYARANDAIILFDAAYEAFITDASLPHSIYEIEGAKEC
EEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHCCCCCCCHHEEECCCHHH
AIEFRSFSKNAGFTGTRCALTVVPKTLKGKAADGSDVELWKLWNRRQSTKFNGVSYIVQR
HHHHHHCCCCCCCCCCEEEEEEECHHHCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHH
GAEAVYSEEGKAQVKGLIQFYLENAKIICSQLQAAGLTVYGGVNAPYVWVQTPTGLSSWD
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCHHH
FFDKLLQNCNVVGTPGSGFGAAGEGYFRISSFNSRENVNEAMKRITEKFKV
HHHHHHHCCEEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATINDNYLKLKAGYLFPEIARRVNTFAEAHPEAQIIKLGIGDVTEPLPKACIQAMTKAV
CCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
AEMGDRSTFKGYGPEQGYAWLREKIAAQDFQGRGCDIDASEIFISDGSKCDSGNILDIIG
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHEEEEECCCCCCCCCEEEEEC
NNNTIAVTDPVYPVYVDTNVMAGNTGAVNEKGEYEGLVYLPIRAENNFTAEIPTQKVDLI
CCCEEEEECCEEEEEEECEEEECCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCCCEE
YLCFPNNPTGATATKEYLQTWVNYARANDAIILFDAAYEAFITDASLPHSIYEIEGAKEC
EEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHCCCCCCCHHEEECCCHHH
AIEFRSFSKNAGFTGTRCALTVVPKTLKGKAADGSDVELWKLWNRRQSTKFNGVSYIVQR
HHHHHHCCCCCCCCCCEEEEEEECHHHCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHH
GAEAVYSEEGKAQVKGLIQFYLENAKIICSQLQAAGLTVYGGVNAPYVWVQTPTGLSSWD
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCHHH
FFDKLLQNCNVVGTPGSGFGAAGEGYFRISSFNSRENVNEAMKRITEKFKV
HHHHHHHCCEEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA