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The map label for this gene is phoP [H]

Identifier: 113476774

GI number: 113476774

Start: 4981509

End: 4981874

Strand: Reverse

Name: phoP [H]

Synonym: Tery_3248

Alternate gene names: 113476774

Gene position: 4981874-4981509 (Counterclockwise)

Preceding gene: 113476775

Following gene: 113476773

Centisome position: 64.28

GC content: 38.52

Gene sequence:

>366_bases
ATGAGCAAAGTTCTAGTGGTAGAAGATAGCGTTACCCAAAGAGAAATGATATCACAGCTTCTCAAAAATAGTGGATTAGC
AGTTACCGTTGCTAATGACGGAGTAGAAGCTTTGGGGCGACTAAAAAATACTAAACCCGATATAGTAGTATTAGATATTG
TGATGCCAAAAATGAATGGTTATGAAGTCTGTAGGAGAATAAAATCCGATCCTCAAACTAAGCATATTCCAGTAGTTATG
TGTTCTTCAAAGGGAGAAGAGTTTGATCGTTACTGGGGCTTAAAACAAGGGGCAGATGCCTATATTGCTAAACCATTCCA
GCCCACAGAACTAGTGGGAACAGTTAAGCAATTATTAAGACGCTAA

Upstream 100 bases:

>100_bases
AATTTAGGTAAGCCCAAAAATCAAAAAATCGGAAAATCTTAAGAAATACTTATACTTTAAACTATTAATCAATCCCAGCC
AAAGCTATCAGGAAAAAAAA

Downstream 100 bases:

>100_bases
ACTTAAGAATCTATGATAGGCAATGAAGATTTTTTACCAAGCCAAGGTATAGGGATCCAAGAATTAGAAAATCCTGAAGG
TGAACAACATTTGCGATTTT

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MSKVLVVEDSVTQREMISQLLKNSGLAVTVANDGVEALGRLKNTKPDIVVLDIVMPKMNGYEVCRRIKSDPQTKHIPVVM
CSSKGEEFDRYWGLKQGADAYIAKPFQPTELVGTVKQLLRR

Sequences:

>Translated_121_residues
MSKVLVVEDSVTQREMISQLLKNSGLAVTVANDGVEALGRLKNTKPDIVVLDIVMPKMNGYEVCRRIKSDPQTKHIPVVM
CSSKGEEFDRYWGLKQGADAYIAKPFQPTELVGTVKQLLRR
>Mature_120_residues
SKVLVVEDSVTQREMISQLLKNSGLAVTVANDGVEALGRLKNTKPDIVVLDIVMPKMNGYEVCRRIKSDPQTKHIPVVMC
SSKGEEFDRYWGLKQGADAYIAKPFQPTELVGTVKQLLRR

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=41.1764705882353, Blast_Score=101, Evalue=2e-23,
Organism=Escherichia coli, GI1788394, Length=119, Percent_Identity=37.8151260504202, Blast_Score=93, Evalue=5e-21,
Organism=Escherichia coli, GI1789809, Length=121, Percent_Identity=40.495867768595, Blast_Score=92, Evalue=1e-20,
Organism=Escherichia coli, GI1790860, Length=118, Percent_Identity=36.4406779661017, Blast_Score=89, Evalue=8e-20,
Organism=Escherichia coli, GI2367329, Length=121, Percent_Identity=37.1900826446281, Blast_Score=81, Evalue=2e-17,
Organism=Escherichia coli, GI1786784, Length=119, Percent_Identity=33.6134453781513, Blast_Score=80, Evalue=3e-17,
Organism=Escherichia coli, GI1786911, Length=121, Percent_Identity=33.8842975206612, Blast_Score=74, Evalue=4e-15,
Organism=Escherichia coli, GI87082012, Length=119, Percent_Identity=30.2521008403361, Blast_Score=73, Evalue=6e-15,
Organism=Escherichia coli, GI1790863, Length=118, Percent_Identity=31.3559322033898, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=31.6666666666667, Blast_Score=69, Evalue=7e-14,
Organism=Escherichia coli, GI1787375, Length=119, Percent_Identity=31.0924369747899, Blast_Score=67, Evalue=3e-13,
Organism=Escherichia coli, GI1787229, Length=119, Percent_Identity=28.5714285714286, Blast_Score=63, Evalue=6e-12,
Organism=Escherichia coli, GI1788550, Length=120, Percent_Identity=30, Blast_Score=63, Evalue=6e-12,
Organism=Escherichia coli, GI1789402, Length=119, Percent_Identity=28.5714285714286, Blast_Score=61, Evalue=2e-11,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=33.3333333333333, Blast_Score=60, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 13518; Mature: 13387

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVLVVEDSVTQREMISQLLKNSGLAVTVANDGVEALGRLKNTKPDIVVLDIVMPKMNG
CCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCEEEEEEECCCCCH
YEVCRRIKSDPQTKHIPVVMCSSKGEEFDRYWGLKQGADAYIAKPFQPTELVGTVKQLLR
HHHHHHHHCCCCCCCCCEEEECCCCCHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHC
R
C
>Mature Secondary Structure 
SKVLVVEDSVTQREMISQLLKNSGLAVTVANDGVEALGRLKNTKPDIVVLDIVMPKMNG
CCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCEEEEEEECCCCCH
YEVCRRIKSDPQTKHIPVVMCSSKGEEFDRYWGLKQGADAYIAKPFQPTELVGTVKQLLR
HHHHHHHHCCCCCCCCCEEEECCCCCHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]