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The map label for this gene is ald2 [H]

Identifier: 113476713

GI number: 113476713

Start: 4847767

End: 4848852

Strand: Reverse

Name: ald2 [H]

Synonym: Tery_3174

Alternate gene names: 113476713

Gene position: 4848852-4847767 (Counterclockwise)

Preceding gene: 113476716

Following gene: 113476712

Centisome position: 62.56

GC content: 40.61

Gene sequence:

>1086_bases
ATGAAAATAGGTATTCCAAAAGAAATTAAGGATCAGGAGTTTCGTGTAGGATTAACCCCTGCAAGTGTTAAGGTCTGTAC
TGAAGCAGGTAATGAAGTATTTATAGAGACAGAAGCTGGTTGGGGCGCAGGTTTTAGTGATAGTGACTATCTTAATGCAG
GCGGGCATATCTTATCAGATACCAGGGACGTTTGGAAGTGTGACATGATAGTTAAGGTTAAGGAACCTCTATCCTCAGAG
TATGAATTTCTCAAATCAGAACAACTGCTATTTACTTATTTACATTTAGCTGCGGATCGGAAGTTAACTAAAAAATTAAT
TGAAAGTGGCGTCACGGCCATCGCCTATGAAACGGTAGAGTTATCTGACCAAAGGCTACCTTTATTAACTCCTATGAGTA
TAATAGCTGGTCGTTTGTCTGTGCAGTTTGGGGCAAGATTTTTGGAAAGACAACAAGGTGGTAGAGGTGTTCTCTTGGGT
GGGGTCCCTGGTGTTACCCCTGGCAAAGTTGTAATTCTGGGAGGAGGAATAGTTGGTACAGAAGCAGCTAAAATTGCTGT
TGGCTTGGGTGCAAAAGTCAAAATTTTGGATATTAATTTGGAAAGGTTGGCTTATTTAGAGACTGTATTTGGCTCAAGGT
TAGAGTTACTATATAGTAGTTCCTCTGCTATAGAAGCAGCAGTCGCAGATTGTGATTTACTTGTAGGGGCAGTTTTAGTT
CCTGGCCGTCGTTCTCCAGTTTTAGTTCCCAAAAGTTTGGTGGAGCAGATGCATTCTGGATCTGTAATTATCGATGTTGC
TGTGGATCAAGGTGGTTGTGTGGAAACTCTACGTCCTACTTCTCATACAAATCCTATCTATCAGGAATTAGGTGTCGTAC
ATTATGGAGTACCTAATATGCCTGGAGCAGTTCCCTGGACAGCTACTCAAGCTTTAAATAATAGTACTTTACCTTATGTA
TTGCAGTTAGCTAACTATGGTAGTAAAGCTTTAGATATGAATCCAGGGTTGGCTAAGGGATTGAATGTTAAAAACCATGT
TTTGGTTCACCCTGCTCTCCGAGAAGTATTTCCTGATTTAAACTAG

Upstream 100 bases:

>100_bases
AACAAATTGTTATCATTTAAGCTAATTAGACCAGATATTTACTCAGACATGATTTTTTGGTCAAAGACATAGTTCCTTGG
TACATAAATGGAGATAGGGA

Downstream 100 bases:

>100_bases
CCAGTTTAATTAACCAATAATTGACATCTTCTGCAAAGCGAAATGATAGAAAGCCCTACATCACTGCGAGACTTTCCTCT
GCCTTTTAGTCGGTTGACAA

Product: L-alanine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MKIGIPKEIKDQEFRVGLTPASVKVCTEAGNEVFIETEAGWGAGFSDSDYLNAGGHILSDTRDVWKCDMIVKVKEPLSSE
YEFLKSEQLLFTYLHLAADRKLTKKLIESGVTAIAYETVELSDQRLPLLTPMSIIAGRLSVQFGARFLERQQGGRGVLLG
GVPGVTPGKVVILGGGIVGTEAAKIAVGLGAKVKILDINLERLAYLETVFGSRLELLYSSSSAIEAAVADCDLLVGAVLV
PGRRSPVLVPKSLVEQMHSGSVIIDVAVDQGGCVETLRPTSHTNPIYQELGVVHYGVPNMPGAVPWTATQALNNSTLPYV
LQLANYGSKALDMNPGLAKGLNVKNHVLVHPALREVFPDLN

Sequences:

>Translated_361_residues
MKIGIPKEIKDQEFRVGLTPASVKVCTEAGNEVFIETEAGWGAGFSDSDYLNAGGHILSDTRDVWKCDMIVKVKEPLSSE
YEFLKSEQLLFTYLHLAADRKLTKKLIESGVTAIAYETVELSDQRLPLLTPMSIIAGRLSVQFGARFLERQQGGRGVLLG
GVPGVTPGKVVILGGGIVGTEAAKIAVGLGAKVKILDINLERLAYLETVFGSRLELLYSSSSAIEAAVADCDLLVGAVLV
PGRRSPVLVPKSLVEQMHSGSVIIDVAVDQGGCVETLRPTSHTNPIYQELGVVHYGVPNMPGAVPWTATQALNNSTLPYV
LQLANYGSKALDMNPGLAKGLNVKNHVLVHPALREVFPDLN
>Mature_361_residues
MKIGIPKEIKDQEFRVGLTPASVKVCTEAGNEVFIETEAGWGAGFSDSDYLNAGGHILSDTRDVWKCDMIVKVKEPLSSE
YEFLKSEQLLFTYLHLAADRKLTKKLIESGVTAIAYETVELSDQRLPLLTPMSIIAGRLSVQFGARFLERQQGGRGVLLG
GVPGVTPGKVVILGGGIVGTEAAKIAVGLGAKVKILDINLERLAYLETVFGSRLELLYSSSSAIEAAVADCDLLVGAVLV
PGRRSPVLVPKSLVEQMHSGSVIIDVAVDQGGCVETLRPTSHTNPIYQELGVVHYGVPNMPGAVPWTATQALNNSTLPYV
LQLANYGSKALDMNPGLAKGLNVKNHVLVHPALREVFPDLN

Specific function: May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=343, Percent_Identity=29.7376093294461, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI122939153, Length=343, Percent_Identity=29.7376093294461, Blast_Score=141, Evalue=8e-34,
Organism=Escherichia coli, GI1787887, Length=368, Percent_Identity=29.3478260869565, Blast_Score=134, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17550456, Length=345, Percent_Identity=27.536231884058, Blast_Score=144, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 38681; Mature: 38681

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00837 ALADH_PNT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGIPKEIKDQEFRVGLTPASVKVCTEAGNEVFIETEAGWGAGFSDSDYLNAGGHILSD
CCCCCCCCCCCCCEEEECCCHHEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCEECC
TRDVWKCDMIVKVKEPLSSEYEFLKSEQLLFTYLHLAADRKLTKKLIESGVTAIAYETVE
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEE
LSDQRLPLLTPMSIIAGRLSVQFGARFLERQQGGRGVLLGGVPGVTPGKVVILGGGIVGT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCEECC
EAAKIAVGLGAKVKILDINLERLAYLETVFGSRLELLYSSSSAIEAAVADCDLLVGAVLV
CHHEEEEECCCEEEEEEECHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHEEC
PGRRSPVLVPKSLVEQMHSGSVIIDVAVDQGGCVETLRPTSHTNPIYQELGVVHYGVPNM
CCCCCCEECCHHHHHHHCCCCEEEEEEECCCCCEECCCCCCCCCHHHHHCCEEEECCCCC
PGAVPWTATQALNNSTLPYVLQLANYGSKALDMNPGLAKGLNVKNHVLVHPALREVFPDL
CCCCCCHHHHHCCCCCCHHHHEEHHCCCCEEECCCCHHHCCCCCCEEEECHHHHHHCCCC
N
C
>Mature Secondary Structure
MKIGIPKEIKDQEFRVGLTPASVKVCTEAGNEVFIETEAGWGAGFSDSDYLNAGGHILSD
CCCCCCCCCCCCCEEEECCCHHEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCEECC
TRDVWKCDMIVKVKEPLSSEYEFLKSEQLLFTYLHLAADRKLTKKLIESGVTAIAYETVE
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEE
LSDQRLPLLTPMSIIAGRLSVQFGARFLERQQGGRGVLLGGVPGVTPGKVVILGGGIVGT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCEECC
EAAKIAVGLGAKVKILDINLERLAYLETVFGSRLELLYSSSSAIEAAVADCDLLVGAVLV
CHHEEEEECCCEEEEEEECHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHEEC
PGRRSPVLVPKSLVEQMHSGSVIIDVAVDQGGCVETLRPTSHTNPIYQELGVVHYGVPNM
CCCCCCEECCHHHHHHHCCCCEEEEEEECCCCCEECCCCCCCCCHHHHHCCEEEECCCCC
PGAVPWTATQALNNSTLPYVLQLANYGSKALDMNPGLAKGLNVKNHVLVHPALREVFPDL
CCCCCCHHHHHCCCCCCHHHHEEHHCCCCEEECCCCHHHCCCCCCEEEECHHHHHHCCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA