Click here to switch to the map view.

The map label for this gene is ywrD [H]

Identifier: 113476240

GI number: 113476240

Start: 4080432

End: 4082018

Strand: Reverse

Name: ywrD [H]

Synonym: Tery_2633

Alternate gene names: 113476240

Gene position: 4082018-4080432 (Counterclockwise)

Preceding gene: 113476241

Following gene: 113476239

Centisome position: 52.67

GC content: 39.07

Gene sequence:

>1587_bases
ATGCGTAATTTTCATAAACCCGAAAGATCAGAAGTGTTTTCACAGAATGGAATGATAGCAACTTCTCATCCTCTAGCTGC
CAAAATTGGTCTTGATACCATGTCCCATGGAGGGAACGCCATAGATGCTGCCATCAGCGCCGCTTTGATGCTCACCTTAT
GTGAACCACAAAGTACCGGGCTCTACGGCGATGCCTTTGTCATTTTAAAATCCCAAAAAAGTGATAAACTCATTGGAATA
AACGGCTCCGGGAACTCCCCCAAGGCAATATCTAGTGATCTGCTCCTCCAAAAAGGCTTGAATAAAATTCCCATTAACAG
CGTGCATTCAATTACACTTCCAGGAGCTGTAGCCTTATTTGAGGAATTAGCTCTTAAATTCAGTAATTTAGGGTTAGCAG
AATTATGTAAAGCATCTATTAAATACGCCGAAGAAGGAGTAGTAGTCAGTCCTAGAGTGGCTTTTGACTGGCGCTTAAAT
AATTTGAAATTTTCTCAAACCACCAAAAAATTCTACTTGGTTGATGGTAAAGTGCCTGAAACTGGGTCAATTTTTAGAGC
TCCAAAGCAAGCGGAAGTTTTGAGAAAAATCCAAAAAAATGGCTCAAAAGGGTTTTATCAGTCTGAGGTTACAGAAGATC
TTGTTAAGTCTTTACAAAACTTGGGGGGAGTTCACACTTTAGATGATTTTGCTAACGTGACATTTGAATATGTAGAGCCA
ATTTTCTCCAATTTTCAAGATGGAAGTAAATTATTTGAGCTGCCTCCTAATGGGCAAGGTATAACTGCTATCATGATCCG
GAAACTCATGGAAATTTGCAACATTCAAGAACATTCTCCATATTCTGCTAACAGGGTACACTTAGAGGCAGAGATCGCAA
AGCTTGCATATACTGCCAGAAATGCTTTTATTGGAGATCCTAAGTTTTCCCAAATTAAAGAACACTTCTTTTTAGACTCA
GCTTTTCTGGAAAAAATTGCTCAACAAATATCTCTCAACAAACTAATAGATGGAAGCGGCATCCAATATTTTGATGAAAA
ACCAAAAGATACCGTTTTAATATCTGCTGCAGATAAAGACGGAAACGCTATCTCTTTAATTTTTTCAAATTTTGATTCGT
TTGGTACTGGAAAATGCTCTGAAAAATACGGTCTCATTTTTCATAACCGCGGAGCTAGTTTTGTTCTTGAGAAAAACCAT
CCTAATGAACTTGAAGGAAATAAAAGACCCTTGCATACTATCATACCTGCTATTTTTAAAGGTAAAAATGACATGATCAT
GGCTTTTGGGGTTATGGGTGGAGACTACCAACCTTATGGTCATGCTCGCATTCTTAGTAATCTTTTTGACTACAGTATGG
ACCCGCAGTCAGCAATAAATTTTCCCAGAAGTTTTTTCTTTAACGGGGTTTTAAAACTAGAAGAGGGCTATGACGAAAAC
GTAGCGGAAGCTTTGACAAGCATAGGTCACAAGATAGTAAGACCCATCGCACCAATAGGAGGGGCTCAGTTGGTCATTTG
TGACCCATCGGGAGTCTTAATAGGGGCTTCAGATCCCAGGAAAGATGGTTGTGCTCTTGGAATTTAG

Upstream 100 bases:

>100_bases
TGTTTGAGATGAATTTGCGGAGGGGTCTAATAGAAAAAAATGCATAATTTTTAAATTTAAATGTTTGAGATGAATTTTCA
GAGGGGTCTAATAGAAAAAA

Downstream 100 bases:

>100_bases
GGTTTTCTGATGCACCCGTTAGCATTCGTATAATTAGATAGTTAATTAGGGGTTATAAATTAGGAGGAAAGAGAATTTAG
AAAGTTTGCTCGTTGCTCAA

Product: gamma-glutamyltransferase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MRNFHKPERSEVFSQNGMIATSHPLAAKIGLDTMSHGGNAIDAAISAALMLTLCEPQSTGLYGDAFVILKSQKSDKLIGI
NGSGNSPKAISSDLLLQKGLNKIPINSVHSITLPGAVALFEELALKFSNLGLAELCKASIKYAEEGVVVSPRVAFDWRLN
NLKFSQTTKKFYLVDGKVPETGSIFRAPKQAEVLRKIQKNGSKGFYQSEVTEDLVKSLQNLGGVHTLDDFANVTFEYVEP
IFSNFQDGSKLFELPPNGQGITAIMIRKLMEICNIQEHSPYSANRVHLEAEIAKLAYTARNAFIGDPKFSQIKEHFFLDS
AFLEKIAQQISLNKLIDGSGIQYFDEKPKDTVLISAADKDGNAISLIFSNFDSFGTGKCSEKYGLIFHNRGASFVLEKNH
PNELEGNKRPLHTIIPAIFKGKNDMIMAFGVMGGDYQPYGHARILSNLFDYSMDPQSAINFPRSFFFNGVLKLEEGYDEN
VAEALTSIGHKIVRPIAPIGGAQLVICDPSGVLIGASDPRKDGCALGI

Sequences:

>Translated_528_residues
MRNFHKPERSEVFSQNGMIATSHPLAAKIGLDTMSHGGNAIDAAISAALMLTLCEPQSTGLYGDAFVILKSQKSDKLIGI
NGSGNSPKAISSDLLLQKGLNKIPINSVHSITLPGAVALFEELALKFSNLGLAELCKASIKYAEEGVVVSPRVAFDWRLN
NLKFSQTTKKFYLVDGKVPETGSIFRAPKQAEVLRKIQKNGSKGFYQSEVTEDLVKSLQNLGGVHTLDDFANVTFEYVEP
IFSNFQDGSKLFELPPNGQGITAIMIRKLMEICNIQEHSPYSANRVHLEAEIAKLAYTARNAFIGDPKFSQIKEHFFLDS
AFLEKIAQQISLNKLIDGSGIQYFDEKPKDTVLISAADKDGNAISLIFSNFDSFGTGKCSEKYGLIFHNRGASFVLEKNH
PNELEGNKRPLHTIIPAIFKGKNDMIMAFGVMGGDYQPYGHARILSNLFDYSMDPQSAINFPRSFFFNGVLKLEEGYDEN
VAEALTSIGHKIVRPIAPIGGAQLVICDPSGVLIGASDPRKDGCALGI
>Mature_528_residues
MRNFHKPERSEVFSQNGMIATSHPLAAKIGLDTMSHGGNAIDAAISAALMLTLCEPQSTGLYGDAFVILKSQKSDKLIGI
NGSGNSPKAISSDLLLQKGLNKIPINSVHSITLPGAVALFEELALKFSNLGLAELCKASIKYAEEGVVVSPRVAFDWRLN
NLKFSQTTKKFYLVDGKVPETGSIFRAPKQAEVLRKIQKNGSKGFYQSEVTEDLVKSLQNLGGVHTLDDFANVTFEYVEP
IFSNFQDGSKLFELPPNGQGITAIMIRKLMEICNIQEHSPYSANRVHLEAEIAKLAYTARNAFIGDPKFSQIKEHFFLDS
AFLEKIAQQISLNKLIDGSGIQYFDEKPKDTVLISAADKDGNAISLIFSNFDSFGTGKCSEKYGLIFHNRGASFVLEKNH
PNELEGNKRPLHTIIPAIFKGKNDMIMAFGVMGGDYQPYGHARILSNLFDYSMDPQSAINFPRSFFFNGVLKLEEGYDEN
VAEALTSIGHKIVRPIAPIGGAQLVICDPSGVLIGASDPRKDGCALGI

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=539, Percent_Identity=25.2319109461967, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI73915090, Length=539, Percent_Identity=25.2319109461967, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI73915096, Length=539, Percent_Identity=25.2319109461967, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI73915094, Length=539, Percent_Identity=25.2319109461967, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI113429324, Length=548, Percent_Identity=25.3649635036496, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI113429326, Length=553, Percent_Identity=24.7739602169982, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI109148539, Length=539, Percent_Identity=22.4489795918367, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1789856, Length=531, Percent_Identity=26.9303201506591, Blast_Score=197, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI72000294, Length=446, Percent_Identity=24.4394618834081, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI212646519, Length=446, Percent_Identity=24.4394618834081, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17506189, Length=485, Percent_Identity=23.7113402061856, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193208245, Length=509, Percent_Identity=22.3968565815324, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193208247, Length=509, Percent_Identity=22.3968565815324, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI161077878, Length=541, Percent_Identity=24.0295748613678, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24642670, Length=541, Percent_Identity=24.0295748613678, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24642666, Length=541, Percent_Identity=24.0295748613678, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI45551474, Length=541, Percent_Identity=24.0295748613678, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI161077880, Length=541, Percent_Identity=24.0295748613678, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI18859893, Length=501, Percent_Identity=23.1536926147705, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI161077496, Length=509, Percent_Identity=22.2003929273084, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI18859741, Length=509, Percent_Identity=20.8251473477407, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 57707; Mature: 57707

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNFHKPERSEVFSQNGMIATSHPLAAKIGLDTMSHGGNAIDAAISAALMLTLCEPQSTG
CCCCCCCHHHHHHHCCCEEEECCCCEEEECCHHHCCCCCHHHHHHHHHHHHHEECCCCCC
LYGDAFVILKSQKSDKLIGINGSGNSPKAISSDLLLQKGLNKIPINSVHSITLPGAVALF
CCCCEEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHH
EELALKFSNLGLAELCKASIKYAEEGVVVSPRVAFDWRLNNLKFSQTTKKFYLVDGKVPE
HHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCEEEEEEECCEEECCCCCEEEEEECCCCC
TGSIFRAPKQAEVLRKIQKNGSKGFYQSEVTEDLVKSLQNLGGVHTLDDFANVTFEYVEP
CCCHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IFSNFQDGSKLFELPPNGQGITAIMIRKLMEICNIQEHSPYSANRVHLEAEIAKLAYTAR
HHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHH
NAFIGDPKFSQIKEHFFLDSAFLEKIAQQISLNKLIDGSGIQYFDEKPKDTVLISAADKD
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCC
GNAISLIFSNFDSFGTGKCSEKYGLIFHNRGASFVLEKNHPNELEGNKRPLHTIIPAIFK
CCEEEEEEECCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHC
GKNDMIMAFGVMGGDYQPYGHARILSNLFDYSMDPQSAINFPRSFFFNGVLKLEEGYDEN
CCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHCCEEEECCCCCHH
VAEALTSIGHKIVRPIAPIGGAQLVICDPSGVLIGASDPRKDGCALGI
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MRNFHKPERSEVFSQNGMIATSHPLAAKIGLDTMSHGGNAIDAAISAALMLTLCEPQSTG
CCCCCCCHHHHHHHCCCEEEECCCCEEEECCHHHCCCCCHHHHHHHHHHHHHEECCCCCC
LYGDAFVILKSQKSDKLIGINGSGNSPKAISSDLLLQKGLNKIPINSVHSITLPGAVALF
CCCCEEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHH
EELALKFSNLGLAELCKASIKYAEEGVVVSPRVAFDWRLNNLKFSQTTKKFYLVDGKVPE
HHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCEEEEEEECCEEECCCCCEEEEEECCCCC
TGSIFRAPKQAEVLRKIQKNGSKGFYQSEVTEDLVKSLQNLGGVHTLDDFANVTFEYVEP
CCCHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IFSNFQDGSKLFELPPNGQGITAIMIRKLMEICNIQEHSPYSANRVHLEAEIAKLAYTAR
HHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHH
NAFIGDPKFSQIKEHFFLDSAFLEKIAQQISLNKLIDGSGIQYFDEKPKDTVLISAADKD
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCC
GNAISLIFSNFDSFGTGKCSEKYGLIFHNRGASFVLEKNHPNELEGNKRPLHTIIPAIFK
CCEEEEEEECCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHC
GKNDMIMAFGVMGGDYQPYGHARILSNLFDYSMDPQSAINFPRSFFFNGVLKLEEGYDEN
CCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHCCEEEECCCCCHH
VAEALTSIGHKIVRPIAPIGGAQLVICDPSGVLIGASDPRKDGCALGI
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]