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The map label for this gene is nadB [H]

Identifier: 113476069

GI number: 113476069

Start: 3767797

End: 3769512

Strand: Direct

Name: nadB [H]

Synonym: Tery_2445

Alternate gene names: 113476069

Gene position: 3767797-3769512 (Clockwise)

Preceding gene: 113476068

Following gene: 113476071

Centisome position: 48.62

GC content: 42.6

Gene sequence:

>1716_bases
ATGCCAAGATTAAATTCTCCAAGTATTTTTCCTCACTTTGACATTATAGTGGTAGGTTCAGGTGCTGCCGGACTTTATGC
GGCTCTTTGTTTACCTGTTCATCTCCGAGTCGCCTTGGTTACTAAAAATACTATAAACATGGGTTCAAGTAACTATGCTC
AGGGAGGTATTGCTGCTGCCATTGATCCTGCGGATAACCCCATCTTGCATCTAGAAGATACTCTCAAAGCAGGTGTAGGT
TTATGTGACCAGGAAGCAGTAAGGTTTATGGTGGACAATGCGGCCAGAGCGATCGCTCATTTAGTAGAAATGGGAGTTGC
CTTCGACCGCAAAGGAAAAAAACTGGCAATGACTCTCGAAGCTGCTCACTCTCATCCCCGGGTGCTTCATTCAGCAGATA
CCACAGGTAGAGCTATTATTGATACACTCGTTATTGAAGCTCAAGAACGTCCAAATATTCAGATAATTTCCCAGGCAGTA
GCATTAAATTTGTGGTTAGCCACACAAAAGGCTCGGGTTCAAGGTATTAGTCTTCTTCACGAAGGTAAAATCCAGTGGTT
AAAATCCTCTGTAGTGGTTTTAGCAACAGGTGGAGGCGGTCAAATATTTGCCCAAACTACTAATCCTGAGGTGAGTACGG
GGGATGGAATTGCTATAGCGTGGCGTGCCGGGGCAGTTTTGCGAGATTTGGAATTTTTCCAATTTCATCCTACTGCCTTA
ATTAAACCAGGAGCACCTCGTTTTCTCATTAGTGAAGCTGTTCGTGGAGAAGGAGCGCACCTAATAGACAATAAGGGAAA
CCGCTTTGCCTTTGAGTATCATCCGGCTGGAGAGTTAGCTCCTAGAGATGTTGTCAGTAGAGCTATTTTCCATCATTTGC
ACAAAACTGCTACCAAGCCTACCAATGCTCATGTTTATTTGGACTTGCGAGCCATTGACTCAGACCGCGTTCGCGACAGA
TTTCCCAATATTATCAATGTCTGTCAAAAATGGGGTATTGATGTTTTTCAAGAACCTATTCCGGTTGCTCCTGCTGCTCA
TTATTGGATGGGTGGAGTGGCTTGCGATCTAATGAGTCAGACTTCAATTCCCGGACTATATGCAATTGGGGAAACAGCAA
GTACAGGAGTTCACGGAGCAAATCGTTTAGCTAGCAATTCTTTGTTAGAATGTTTAGTATTTGCTTCTCAACTATCTCAG
ATTGAAATTGAGCCAAATTTGGTGGCACCTGATGCTGATATTTTTCAGGTAAGTTCTAATTGGAATATGGAAATGGAACA
GATAGAGGCTATCCGACAAATGTTACCAAGTTTAATGTGGGAAAGTGCAGGAATTTCTCGTAAAGGAGAGTCATTAAGTC
AGGCACTATATCAGGTGGCGCGCTGGCGAGATAGTTTAGCAAGTTTTGAGATAGTTAAGTTTTTAGCTAATCTCTTGCCT
AACCAGACGATAAAATTAAATTCGACTAATGCTGAAGAGCAGTTGCGGATAACAGCAGAAACACTCAATATTTTAGACTT
GGGTTATTTAATTCTTAAAAGTGCTGCATGGCGAACTGAAAGCAGAGGTGGGCATTATCGCAGTGATTATCCAAAAACTT
CTAATGATTGGAAACTACATACTTTGGTTCAGGGCGATCGCTTATTAACTGGTTTTCCAAATGCCTCGCCCCCTGGCCAA
GAGAGAGGGTCTTCAGTCAACATTGAAAAATTTTGA

Upstream 100 bases:

>100_bases
TAACTTCTATTATAAATATTCCCTAAAATCAACTTTAGAAAAGACTTGTTCAAAAAATGTTGTACAGGAATTTATTCTAT
ACAAAAATATACTTTTACAG

Downstream 100 bases:

>100_bases
ATACAGGACTTACGCTGGTGCACTACACCAGCGTAAGTCCTGTAATAGTTACAGAGTTGAGATCTAGTTGACTTCATAAG
AGGGAATTGGATGTGTTGGC

Product: L-aspartate oxidase

Products: NA

Alternate protein names: LASPO; Quinolinate synthase B [H]

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MPRLNSPSIFPHFDIIVVGSGAAGLYAALCLPVHLRVALVTKNTINMGSSNYAQGGIAAAIDPADNPILHLEDTLKAGVG
LCDQEAVRFMVDNAARAIAHLVEMGVAFDRKGKKLAMTLEAAHSHPRVLHSADTTGRAIIDTLVIEAQERPNIQIISQAV
ALNLWLATQKARVQGISLLHEGKIQWLKSSVVVLATGGGGQIFAQTTNPEVSTGDGIAIAWRAGAVLRDLEFFQFHPTAL
IKPGAPRFLISEAVRGEGAHLIDNKGNRFAFEYHPAGELAPRDVVSRAIFHHLHKTATKPTNAHVYLDLRAIDSDRVRDR
FPNIINVCQKWGIDVFQEPIPVAPAAHYWMGGVACDLMSQTSIPGLYAIGETASTGVHGANRLASNSLLECLVFASQLSQ
IEIEPNLVAPDADIFQVSSNWNMEMEQIEAIRQMLPSLMWESAGISRKGESLSQALYQVARWRDSLASFEIVKFLANLLP
NQTIKLNSTNAEEQLRITAETLNILDLGYLILKSAAWRTESRGGHYRSDYPKTSNDWKLHTLVQGDRLLTGFPNASPPGQ
ERGSSVNIEKF

Sequences:

>Translated_571_residues
MPRLNSPSIFPHFDIIVVGSGAAGLYAALCLPVHLRVALVTKNTINMGSSNYAQGGIAAAIDPADNPILHLEDTLKAGVG
LCDQEAVRFMVDNAARAIAHLVEMGVAFDRKGKKLAMTLEAAHSHPRVLHSADTTGRAIIDTLVIEAQERPNIQIISQAV
ALNLWLATQKARVQGISLLHEGKIQWLKSSVVVLATGGGGQIFAQTTNPEVSTGDGIAIAWRAGAVLRDLEFFQFHPTAL
IKPGAPRFLISEAVRGEGAHLIDNKGNRFAFEYHPAGELAPRDVVSRAIFHHLHKTATKPTNAHVYLDLRAIDSDRVRDR
FPNIINVCQKWGIDVFQEPIPVAPAAHYWMGGVACDLMSQTSIPGLYAIGETASTGVHGANRLASNSLLECLVFASQLSQ
IEIEPNLVAPDADIFQVSSNWNMEMEQIEAIRQMLPSLMWESAGISRKGESLSQALYQVARWRDSLASFEIVKFLANLLP
NQTIKLNSTNAEEQLRITAETLNILDLGYLILKSAAWRTESRGGHYRSDYPKTSNDWKLHTLVQGDRLLTGFPNASPPGQ
ERGSSVNIEKF
>Mature_570_residues
PRLNSPSIFPHFDIIVVGSGAAGLYAALCLPVHLRVALVTKNTINMGSSNYAQGGIAAAIDPADNPILHLEDTLKAGVGL
CDQEAVRFMVDNAARAIAHLVEMGVAFDRKGKKLAMTLEAAHSHPRVLHSADTTGRAIIDTLVIEAQERPNIQIISQAVA
LNLWLATQKARVQGISLLHEGKIQWLKSSVVVLATGGGGQIFAQTTNPEVSTGDGIAIAWRAGAVLRDLEFFQFHPTALI
KPGAPRFLISEAVRGEGAHLIDNKGNRFAFEYHPAGELAPRDVVSRAIFHHLHKTATKPTNAHVYLDLRAIDSDRVRDRF
PNIINVCQKWGIDVFQEPIPVAPAAHYWMGGVACDLMSQTSIPGLYAIGETASTGVHGANRLASNSLLECLVFASQLSQI
EIEPNLVAPDADIFQVSSNWNMEMEQIEAIRQMLPSLMWESAGISRKGESLSQALYQVARWRDSLASFEIVKFLANLLPN
QTIKLNSTNAEEQLRITAETLNILDLGYLILKSAAWRTESRGGHYRSDYPKTSNDWKLHTLVQGDRLLTGFPNASPPGQE
RGSSVNIEKF

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=551, Percent_Identity=30.4900181488203, Blast_Score=216, Evalue=3e-56,
Organism=Escherichia coli, GI1788928, Length=548, Percent_Identity=38.6861313868613, Blast_Score=355, Evalue=3e-99,
Organism=Escherichia coli, GI1786942, Length=544, Percent_Identity=31.6176470588235, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1790597, Length=531, Percent_Identity=30.5084745762712, Blast_Score=226, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17505833, Length=553, Percent_Identity=31.8264014466546, Blast_Score=223, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17550100, Length=544, Percent_Identity=32.9044117647059, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI71986328, Length=459, Percent_Identity=29.4117647058824, Blast_Score=118, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6322701, Length=531, Percent_Identity=32.9566854990584, Blast_Score=214, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6322416, Length=532, Percent_Identity=32.8947368421053, Blast_Score=209, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6322511, Length=471, Percent_Identity=29.5116772823779, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320788, Length=482, Percent_Identity=27.5933609958506, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17137288, Length=550, Percent_Identity=31.0909090909091, Blast_Score=215, Evalue=5e-56,
Organism=Drosophila melanogaster, GI24655642, Length=550, Percent_Identity=31.0909090909091, Blast_Score=215, Evalue=5e-56,
Organism=Drosophila melanogaster, GI24655647, Length=550, Percent_Identity=31.0909090909091, Blast_Score=215, Evalue=5e-56,
Organism=Drosophila melanogaster, GI24663005, Length=540, Percent_Identity=31.4814814814815, Blast_Score=204, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 62336; Mature: 62205

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLNSPSIFPHFDIIVVGSGAAGLYAALCLPVHLRVALVTKNTINMGSSNYAQGGIAAA
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHEEEEEEEECEECCCCCCCCCCCEEEE
IDPADNPILHLEDTLKAGVGLCDQEAVRFMVDNAARAIAHLVEMGVAFDRKGKKLAMTLE
ECCCCCCEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
AAHSHPRVLHSADTTGRAIIDTLVIEAQERPNIQIISQAVALNLWLATQKARVQGISLLH
CCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHEEEEECHHHHHHHHHHHH
EGKIQWLKSSVVVLATGGGGQIFAQTTNPEVSTGDGIAIAWRAGAVLRDLEFFQFHPTAL
HCHHHEEECCEEEEEECCCCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHEECCCEE
IKPGAPRFLISEAVRGEGAHLIDNKGNRFAFEYHPAGELAPRDVVSRAIFHHLHKTATKP
ECCCCCHHHHHHHHCCCCCEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
TNAHVYLDLRAIDSDRVRDRFPNIINVCQKWGIDVFQEPIPVAPAAHYWMGGVACDLMSQ
CCCEEEEEEEECCCHHHHHHCHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHH
TSIPGLYAIGETASTGVHGANRLASNSLLECLVFASQLSQIEIEPNLVAPDADIFQVSSN
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCEECCCCCEEEECCC
WNMEMEQIEAIRQMLPSLMWESAGISRKGESLSQALYQVARWRDSLASFEIVKFLANLLP
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NQTIKLNSTNAEEQLRITAETLNILDLGYLILKSAAWRTESRGGHYRSDYPKTSNDWKLH
CCEEEECCCCCHHHEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEE
TLVQGDRLLTGFPNASPPGQERGSSVNIEKF
EEEECCEEEECCCCCCCCCHHCCCCCCCCCC
>Mature Secondary Structure 
PRLNSPSIFPHFDIIVVGSGAAGLYAALCLPVHLRVALVTKNTINMGSSNYAQGGIAAA
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHEEEEEEEECEECCCCCCCCCCCEEEE
IDPADNPILHLEDTLKAGVGLCDQEAVRFMVDNAARAIAHLVEMGVAFDRKGKKLAMTLE
ECCCCCCEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
AAHSHPRVLHSADTTGRAIIDTLVIEAQERPNIQIISQAVALNLWLATQKARVQGISLLH
CCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHEEEEECHHHHHHHHHHHH
EGKIQWLKSSVVVLATGGGGQIFAQTTNPEVSTGDGIAIAWRAGAVLRDLEFFQFHPTAL
HCHHHEEECCEEEEEECCCCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHEECCCEE
IKPGAPRFLISEAVRGEGAHLIDNKGNRFAFEYHPAGELAPRDVVSRAIFHHLHKTATKP
ECCCCCHHHHHHHHCCCCCEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
TNAHVYLDLRAIDSDRVRDRFPNIINVCQKWGIDVFQEPIPVAPAAHYWMGGVACDLMSQ
CCCEEEEEEEECCCHHHHHHCHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHH
TSIPGLYAIGETASTGVHGANRLASNSLLECLVFASQLSQIEIEPNLVAPDADIFQVSSN
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCEECCCCCEEEECCC
WNMEMEQIEAIRQMLPSLMWESAGISRKGESLSQALYQVARWRDSLASFEIVKFLANLLP
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NQTIKLNSTNAEEQLRITAETLNILDLGYLILKSAAWRTESRGGHYRSDYPKTSNDWKLH
CCEEEECCCCCHHHEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEE
TLVQGDRLLTGFPNASPPGQERGSSVNIEKF
EEEECCEEEECCCCCCCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]