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The map label for this gene is clpB [H]

Identifier: 113476064

GI number: 113476064

Start: 3755804

End: 3758281

Strand: Direct

Name: clpB [H]

Synonym: Tery_2437

Alternate gene names: 113476064

Gene position: 3755804-3758281 (Clockwise)

Preceding gene: 113476063

Following gene: 113476068

Centisome position: 48.46

GC content: 43.06

Gene sequence:

>2478_bases
ATGTTTGAACGCTTCACGGAAAAAGCAATCAAAGTGATAATGCTGGCCCAAGAAGAGGCTCGTCGCTTGGGACATAACTT
TGTAGGGACAGAACAAATCCTCCTGGGTCTCATTGGAGAGGGAACAGGGGTAGCAGCTAAAGTTCTCAAATCTATGGGTG
TTAATCTCAAAGATGCTCGAATTGAAGTAGAAAAGATAATTGGCCGTGGTTCGGGATTTGTGGCAGTAGAAATCCCATTT
ACTCCCAGAGCTAAAAGGGTTTTAGAGCTATCTTTGGAAGAAGCACGGCAATTAGGGCATAACTATATTGGCACAGAGCA
TCTACTATTGGGTTTAATTCGAGAAGGAGAAGGAGTAGCTGCAAGAGTTCTAGAAAATTTAGGAGTAGACCTCACTAAAG
TCCGGACTCAGGTGATTAGAATGTTAGGTGAAACAGCAGAAGTTACTGCTGGTGGTGGGGGTGGACGCACAAAAACTCCT
ACTCTTGATGAGTTTGGTTCAAATCTGACTCAAATGGCATCTGAAGGTAAATTAGACCCAGTGGTGGGAAGGCAAACAGA
AATAGAACGAGTAATTCAAATTTTAGGTCGTAGAACTAAGAATAATCCAGTTTTGATTGGGGAACCTGGTGTGGGAAAAA
CGGCGATCGCTGAGGGTTTGGCACAACGCATTGCTAATAATGATATACCGGATATTCTGGAAGAAAAGCGGGTGGTTACT
CTAGATATTGGTCTATTGGTTGCTGGTACTAAATACCGGGGTGAGTTTGAGGAACGTCTGAAGAAAATTATGGATGAAAT
TCGCTCTGCGGGTAATGTCATCCTAGTTATTGATGAGGTCCATACTCTGATTGGAGCTGGTGCTGCGGAAGGGGCCATTG
ATGCTGCGAATATTTTGAAGCCTGCTTTGGCTCGTGGGGAGTTACAGTGCATAGGGGCAACGACCCTCGATGAGTATCGG
AAACATATTGAAAGGGATGCAGCTCTGGAACGTCGTTTTCAACCAGTAATGGTGGGCGAACCTTCTGTTGATGAAACTAT
TGAGATCTTATATGGTTTAAGAGAACGTTACGAACAGCATCATAAATTAAAAATTTTGGATACTGCTTTGGAAGCTGCTG
CTAAGTTATCAGACCGTTATATTAGCGATCGCTATTTGCCGGATAAAGCTATTGACCTGATAGATGAAGCTGGTTCTCGT
GTCCGTTTGATTAATTCTCAACTACCTCCTGCAGCGAAGGAACTGGATAAGGAGTTGCGTAGCATTCTGAAAGAAAAGGA
TGAGGCGGTTCGTTCTCAGGATTTTGATAAGGCGGGAGAGTTGCGTGACCGGGAAATGGAAATCAAATCTGAAATTCGTT
CTCTTGCTCAAAATAAAAAGCTCGACTCTACTAATGAAGATGATTCTCCAATGGTGACTGAGGAGGATATTGCTCATATT
GTGGCAAGTTGGACTGGTGTTCCGGTGAATAAGTTAACTGAGTCTGAATCTGAGAAACTTCTGCACATGGAGGATACTCT
ACACCAACGTTTGATTGGTCAGGAGGAAGCTGTCAAGGCAGTGTCTCGTGCTATTCGTCGGGCAAGAGTGGGATTGAAAA
ACCCTAACCGACCTATTGCTAGTTTTGTTTTCTCTGGACCGACTGGGGTTGGTAAGACAGAACTGACTAAGGCGTTAGCT
GCATATTTCTTTGGTTCTGAGGAAGCGATGATCCGTTTGGATATGTCGGAATATATGGAACGTCATACTGTTTCTAAGTT
GATTGGTTCTCCTCCTGGTTATGTGGGTTATAATGAGGGTGGTCAGTTAACTGAGGCAGTTCGTCGTCGCCCTTATACTG
TGGTGCTATTTGATGAAATTGAAAAGGCACACCCTGATGTATTCAATATGCTGTTGCAAATTTTGGAAGATGGTCGCCTG
ACTGATGCGAAGGGTAGGACTGTTGATTTTAAGAATACCTTGATTATTATGACTTCTAATATCGGTTCTAAGGTCATTGA
GAAAGGTGGCGGTGGTCTTGGTTTTGAGTTCTCAGAAAATGAGGCTGATGCTCAGTATAACCGAATTCGCAATTTAGTGA
ATGAGGAGTTGAAACAGTATTTCCGTCCAGAGTTTCTTAACCGTTTGGATGAGATTATTGTGTTCCGTCAGTTGACTAAG
GATGAAGTTAAGGAAATTTCTGTTATTCTGCTCAAAGAAGTGTTTAGTAGGTTGACAGAGAAAGGTATTAAGTTAGAAAT
TACTGATCGTTTCCAGGAGCGGTTGGTTGAGGAAGGTTATAATCCTAGTTATGGGGCAAGACCTTTGCGTCGGGCAATTA
TGCGTTTGCTTGAGGATAGTTTGGCTGAGGAAATTCTGGCTGGCAAGATCAATGAGGGCGATACTGCTGTGGTTGATGTT
GGGGAAAGTGGTCAGATTATAGTTTCTAAGGGTGAAGAAAAAGAAAAACGAGAGTTGGTACCTCAAGGTGCTGAATAG

Upstream 100 bases:

>100_bases
AAGTATTTCTAGTCTAAATAACGAGAAGTGAAAAACAGCCTTGGTATACAATGTCACGCTAGAATAAGCTTAAGAGCAAT
TTAAGAGATAGGAACTAATT

Downstream 100 bases:

>100_bases
GAGTTAGTTTCTTTCGCTAAATTAGTCAATATCTAATGTTGAAACGGCAGTAAGTTTAAATTTACTGCCGTTTCGAGGTA
TTATATTATTTCGGAAGTAT

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 825; Mature: 825

Protein sequence:

>825_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDARIEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLTKVRTQVIRMLGETAEVTAGGGGGRTKTP
TLDEFGSNLTQMASEGKLDPVVGRQTEIERVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIANNDIPDILEEKRVVT
LDIGLLVAGTKYRGEFEERLKKIMDEIRSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDEYR
KHIERDAALERRFQPVMVGEPSVDETIEILYGLRERYEQHHKLKILDTALEAAAKLSDRYISDRYLPDKAIDLIDEAGSR
VRLINSQLPPAAKELDKELRSILKEKDEAVRSQDFDKAGELRDREMEIKSEIRSLAQNKKLDSTNEDDSPMVTEEDIAHI
VASWTGVPVNKLTESESEKLLHMEDTLHQRLIGQEEAVKAVSRAIRRARVGLKNPNRPIASFVFSGPTGVGKTELTKALA
AYFFGSEEAMIRLDMSEYMERHTVSKLIGSPPGYVGYNEGGQLTEAVRRRPYTVVLFDEIEKAHPDVFNMLLQILEDGRL
TDAKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSENEADAQYNRIRNLVNEELKQYFRPEFLNRLDEIIVFRQLTK
DEVKEISVILLKEVFSRLTEKGIKLEITDRFQERLVEEGYNPSYGARPLRRAIMRLLEDSLAEEILAGKINEGDTAVVDV
GESGQIIVSKGEEKEKRELVPQGAE

Sequences:

>Translated_825_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDARIEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLTKVRTQVIRMLGETAEVTAGGGGGRTKTP
TLDEFGSNLTQMASEGKLDPVVGRQTEIERVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIANNDIPDILEEKRVVT
LDIGLLVAGTKYRGEFEERLKKIMDEIRSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDEYR
KHIERDAALERRFQPVMVGEPSVDETIEILYGLRERYEQHHKLKILDTALEAAAKLSDRYISDRYLPDKAIDLIDEAGSR
VRLINSQLPPAAKELDKELRSILKEKDEAVRSQDFDKAGELRDREMEIKSEIRSLAQNKKLDSTNEDDSPMVTEEDIAHI
VASWTGVPVNKLTESESEKLLHMEDTLHQRLIGQEEAVKAVSRAIRRARVGLKNPNRPIASFVFSGPTGVGKTELTKALA
AYFFGSEEAMIRLDMSEYMERHTVSKLIGSPPGYVGYNEGGQLTEAVRRRPYTVVLFDEIEKAHPDVFNMLLQILEDGRL
TDAKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSENEADAQYNRIRNLVNEELKQYFRPEFLNRLDEIIVFRQLTK
DEVKEISVILLKEVFSRLTEKGIKLEITDRFQERLVEEGYNPSYGARPLRRAIMRLLEDSLAEEILAGKINEGDTAVVDV
GESGQIIVSKGEEKEKRELVPQGAE
>Mature_825_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDARIEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLTKVRTQVIRMLGETAEVTAGGGGGRTKTP
TLDEFGSNLTQMASEGKLDPVVGRQTEIERVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIANNDIPDILEEKRVVT
LDIGLLVAGTKYRGEFEERLKKIMDEIRSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDEYR
KHIERDAALERRFQPVMVGEPSVDETIEILYGLRERYEQHHKLKILDTALEAAAKLSDRYISDRYLPDKAIDLIDEAGSR
VRLINSQLPPAAKELDKELRSILKEKDEAVRSQDFDKAGELRDREMEIKSEIRSLAQNKKLDSTNEDDSPMVTEEDIAHI
VASWTGVPVNKLTESESEKLLHMEDTLHQRLIGQEEAVKAVSRAIRRARVGLKNPNRPIASFVFSGPTGVGKTELTKALA
AYFFGSEEAMIRLDMSEYMERHTVSKLIGSPPGYVGYNEGGQLTEAVRRRPYTVVLFDEIEKAHPDVFNMLLQILEDGRL
TDAKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSENEADAQYNRIRNLVNEELKQYFRPEFLNRLDEIIVFRQLTK
DEVKEISVILLKEVFSRLTEKGIKLEITDRFQERLVEEGYNPSYGARPLRRAIMRLLEDSLAEEILAGKINEGDTAVVDV
GESGQIIVSKGEEKEKRELVPQGAE

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=298, Percent_Identity=39.9328859060403, Blast_Score=206, Evalue=9e-53,
Organism=Escherichia coli, GI1788943, Length=868, Percent_Identity=46.889400921659, Blast_Score=740, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=821, Percent_Identity=37.7588306942753, Blast_Score=527, Evalue=1e-150,
Organism=Saccharomyces cerevisiae, GI6320464, Length=712, Percent_Identity=48.0337078651685, Blast_Score=634, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=901, Percent_Identity=36.7369589345172, Blast_Score=551, Evalue=1e-157,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 91708; Mature: 91708

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDAR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHH
IEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
ARVLENLGVDLTKVRTQVIRMLGETAEVTAGGGGGRTKTPTLDEFGSNLTQMASEGKLDP
HHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHCCHHHHHHHCCCCCC
VVGRQTEIERVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIANNDIPDILEEKRVVT
CCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHCCCEEE
LDIGLLVAGTKYRGEFEERLKKIMDEIRSAGNVILVIDEVHTLIGAGAAEGAIDAANILK
EEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCHHHHHHH
PALARGELQCIGATTLDEYRKHIERDAALERRFQPVMVGEPSVDETIEILYGLRERYEQH
HHHHCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHH
HKLKILDTALEAAAKLSDRYISDRYLPDKAIDLIDEAGSRVRLINSQLPPAAKELDKELR
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHH
SILKEKDEAVRSQDFDKAGELRDREMEIKSEIRSLAQNKKLDSTNEDDSPMVTEEDIAHI
HHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
VASWTGVPVNKLTESESEKLLHMEDTLHQRLIGQEEAVKAVSRAIRRARVGLKNPNRPIA
HHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHH
SFVFSGPTGVGKTELTKALAAYFFGSEEAMIRLDMSEYMERHTVSKLIGSPPGYVGYNEG
HHEECCCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCC
GQLTEAVRRRPYTVVLFDEIEKAHPDVFNMLLQILEDGRLTDAKGRTVDFKNTLIIMTSN
CHHHHHHHHCCCEEEEEHHHHHHCHHHHHHHHHHHHCCCEECCCCCEEECCCEEEEEECC
IGSKVIEKGGGGLGFEFSENEADAQYNRIRNLVNEELKQYFRPEFLNRLDEIIVFRQLTK
CCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
DEVKEISVILLKEVFSRLTEKGIKLEITDRFQERLVEEGYNPSYGARPLRRAIMRLLEDS
HHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LAEEILAGKINEGDTAVVDVGESGQIIVSKGEEKEKRELVPQGAE
HHHHHHHCCCCCCCEEEEEECCCCCEEEECCCCHHHHHCCCCCCC
>Mature Secondary Structure
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDAR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHH
IEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
ARVLENLGVDLTKVRTQVIRMLGETAEVTAGGGGGRTKTPTLDEFGSNLTQMASEGKLDP
HHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHCCHHHHHHHCCCCCC
VVGRQTEIERVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIANNDIPDILEEKRVVT
CCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHCCCEEE
LDIGLLVAGTKYRGEFEERLKKIMDEIRSAGNVILVIDEVHTLIGAGAAEGAIDAANILK
EEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCHHHHHHH
PALARGELQCIGATTLDEYRKHIERDAALERRFQPVMVGEPSVDETIEILYGLRERYEQH
HHHHCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHH
HKLKILDTALEAAAKLSDRYISDRYLPDKAIDLIDEAGSRVRLINSQLPPAAKELDKELR
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHH
SILKEKDEAVRSQDFDKAGELRDREMEIKSEIRSLAQNKKLDSTNEDDSPMVTEEDIAHI
HHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
VASWTGVPVNKLTESESEKLLHMEDTLHQRLIGQEEAVKAVSRAIRRARVGLKNPNRPIA
HHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHH
SFVFSGPTGVGKTELTKALAAYFFGSEEAMIRLDMSEYMERHTVSKLIGSPPGYVGYNEG
HHEECCCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCC
GQLTEAVRRRPYTVVLFDEIEKAHPDVFNMLLQILEDGRLTDAKGRTVDFKNTLIIMTSN
CHHHHHHHHCCCEEEEEHHHHHHCHHHHHHHHHHHHCCCEECCCCCEEECCCEEEEEECC
IGSKVIEKGGGGLGFEFSENEADAQYNRIRNLVNEELKQYFRPEFLNRLDEIIVFRQLTK
CCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
DEVKEISVILLKEVFSRLTEKGIKLEITDRFQERLVEEGYNPSYGARPLRRAIMRLLEDS
HHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LAEEILAGKINEGDTAVVDVGESGQIIVSKGEEKEKRELVPQGAE
HHHHHHHCCCCCCCEEEEEECCCCCEEEECCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]